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The map label for this gene is opdE [H]

Identifier: 189352497

GI number: 189352497

Start: 552301

End: 553524

Strand: Reverse

Name: opdE [H]

Synonym: BMULJ_03717

Alternate gene names: 189352497

Gene position: 553524-552301 (Counterclockwise)

Preceding gene: 189352501

Following gene: 189352496

Centisome position: 22.38

GC content: 60.78

Gene sequence:

>1224_bases
ATGTCTACCGAGCTATGTGATACCCCTGCGCGAGAGTTTCCTGCGCAACAGACGTCGCCCACGCAGCCCGCATTCTGGGG
TGGCGTTTTCGCCATGACCATCTGCGTCTTCGCTTTGATTGCGTCCGAGTTTATGCCCGTGAGCCTGCTGACGCCGATGG
CAACGGATTTTCACGTCACCGAGGGCCTTGCGGGGCGTGGCATCGCAATATCGGGAGCATTTGCTGTCTTGACGAGCCTT
TTCATCTCCAGCGTCGCTGGCAGCATGAATCGCAAGACTCTGTTGCTTACGCTGACAGTCTTGATGGCCTTGTCGGGCGC
AGTAATCGCCGTCGCGCCGAACTATGTCACGTATATGGTGGGGCGCGCGTTGATTGGTGTAGTGGTCGGCGGATTCTGGT
CGATGTCCGCGGCGACCGCCATGCGGCTGGTTCCCGCCGCCGACGTTCCACGTGCCCTCGCCATTTTCAATAGTGGGAAC
GCGTTGGCCACGGTTATCGCCGCGCCGCTCGGCAGCTATCTGGGCTCGGTCATCGGTTGGCGTGGTGCGTTCTTCTCTCT
CGTGCCAATCGCGTTGATTGCGCTTGTCTGGCAATGGAAAAGCTTGCCCGAGATGCCCGTCAACGCGCGACGCGCCCAGT
CGGTCAGGATCTTCTCGCTCTTTCGGCGCCGCATCGTGACGCTCGGCATGCTTGCCTCCGGCATGTTCTTCATGGGGCAG
TTCGCGCTTTTCACTTATGTCCGGCCGTTTTTGGAGACGGTGACACGCGTCGATGTTTCCACGCTGTCTTTGATCTTGCT
CGTGATTGGCATCACGGGATTCATTGGTACAGCGCTGATCGGTGGCGTGCTAAAGCGCAGCTTCTACCCGACTCTTATTG
CGATTCCCGTCCTCATGGCGGCAGTCGCGGCCGCACTCATGATTGTCGGCGACCGGACCACTGCCGTGGTCGTGCTGCTC
GGATCATGGGGGCTACTTGCGACCGCTGCTCCAGTCGGCTGGTGGGGCTGGGTTGCCAGAACGTTTCCCGATAACGCGGA
AGCCGGCGGCGGGCTGCTGGTCGCCATCGTGCAACTGGCTATTGCGTCCGGTTCCACCGGAGGGGGCCTGCTCTTCGACA
GTCACGGCTACCGCGGGACCTTTCTCGCAAGTGTCGTGCTGTTGCTGATTGCGGCTTTCCTGACTTTCCTGACGTCCCGC
TCCGACACCGCGTCGGCGAGTTGA

Upstream 100 bases:

>100_bases
GTCGGCTGGAACTCGTACTCGATGCAAAGGGCTGAACCATTAGTCCTCGCGTCGGGGCATGGGCGCCTGCAGCCGCGCTT
CTCGAATCCCTGGATCGCCA

Downstream 100 bases:

>100_bases
TCAACCAATTACGAGGGTTCAAATCATGACGGTCAAAGCATACGGAGCCTATGCCGGCGACAAAGCTCTTGAATCGATGG
ACATCGTCCGCCGCGCGCCG

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSTELCDTPAREFPAQQTSPTQPAFWGGVFAMTICVFALIASEFMPVSLLTPMATDFHVTEGLAGRGIAISGAFAVLTSL
FISSVAGSMNRKTLLLTLTVLMALSGAVIAVAPNYVTYMVGRALIGVVVGGFWSMSAATAMRLVPAADVPRALAIFNSGN
ALATVIAAPLGSYLGSVIGWRGAFFSLVPIALIALVWQWKSLPEMPVNARRAQSVRIFSLFRRRIVTLGMLASGMFFMGQ
FALFTYVRPFLETVTRVDVSTLSLILLVIGITGFIGTALIGGVLKRSFYPTLIAIPVLMAAVAAALMIVGDRTTAVVVLL
GSWGLLATAAPVGWWGWVARTFPDNAEAGGGLLVAIVQLAIASGSTGGGLLFDSHGYRGTFLASVVLLLIAAFLTFLTSR
SDTASAS

Sequences:

>Translated_407_residues
MSTELCDTPAREFPAQQTSPTQPAFWGGVFAMTICVFALIASEFMPVSLLTPMATDFHVTEGLAGRGIAISGAFAVLTSL
FISSVAGSMNRKTLLLTLTVLMALSGAVIAVAPNYVTYMVGRALIGVVVGGFWSMSAATAMRLVPAADVPRALAIFNSGN
ALATVIAAPLGSYLGSVIGWRGAFFSLVPIALIALVWQWKSLPEMPVNARRAQSVRIFSLFRRRIVTLGMLASGMFFMGQ
FALFTYVRPFLETVTRVDVSTLSLILLVIGITGFIGTALIGGVLKRSFYPTLIAIPVLMAAVAAALMIVGDRTTAVVVLL
GSWGLLATAAPVGWWGWVARTFPDNAEAGGGLLVAIVQLAIASGSTGGGLLFDSHGYRGTFLASVVLLLIAAFLTFLTSR
SDTASAS
>Mature_406_residues
STELCDTPAREFPAQQTSPTQPAFWGGVFAMTICVFALIASEFMPVSLLTPMATDFHVTEGLAGRGIAISGAFAVLTSLF
ISSVAGSMNRKTLLLTLTVLMALSGAVIAVAPNYVTYMVGRALIGVVVGGFWSMSAATAMRLVPAADVPRALAIFNSGNA
LATVIAAPLGSYLGSVIGWRGAFFSLVPIALIALVWQWKSLPEMPVNARRAQSVRIFSLFRRRIVTLGMLASGMFFMGQF
ALFTYVRPFLETVTRVDVSTLSLILLVIGITGFIGTALIGGVLKRSFYPTLIAIPVLMAAVAAALMIVGDRTTAVVVLLG
SWGLLATAAPVGWWGWVARTFPDNAEAGGGLLVAIVQLAIASGSTGGGLLFDSHGYRGTFLASVVLLLIAAFLTFLTSRS
DTASAS

Specific function: Regulates the expression of oprD which encodes the imipenem-specific porin [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ywfA [H]

Homologues:

Organism=Escherichia coli, GI145693198, Length=387, Percent_Identity=39.5348837209302, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1787947, Length=271, Percent_Identity=28.7822878228782, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787808, Length=230, Percent_Identity=27.8260869565217, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786595, Length=311, Percent_Identity=25.7234726688103, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42687; Mature: 42556

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTELCDTPAREFPAQQTSPTQPAFWGGVFAMTICVFALIASEFMPVSLLTPMATDFHVT
CCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHH
EGLAGRGIAISGAFAVLTSLFISSVAGSMNRKTLLLTLTVLMALSGAVIAVAPNYVTYMV
CCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHH
GRALIGVVVGGFWSMSAATAMRLVPAADVPRALAIFNSGNALATVIAAPLGSYLGSVIGW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
RGAFFSLVPIALIALVWQWKSLPEMPVNARRAQSVRIFSLFRRRIVTLGMLASGMFFMGQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FALFTYVRPFLETVTRVDVSTLSLILLVIGITGFIGTALIGGVLKRSFYPTLIAIPVLMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAAALMIVGDRTTAVVVLLGSWGLLATAAPVGWWGWVARTFPDNAEAGGGLLVAIVQLA
HHHHHHHHHCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
IASGSTGGGLLFDSHGYRGTFLASVVLLLIAAFLTFLTSRSDTASAS
HHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
STELCDTPAREFPAQQTSPTQPAFWGGVFAMTICVFALIASEFMPVSLLTPMATDFHVT
CCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHH
EGLAGRGIAISGAFAVLTSLFISSVAGSMNRKTLLLTLTVLMALSGAVIAVAPNYVTYMV
CCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHH
GRALIGVVVGGFWSMSAATAMRLVPAADVPRALAIFNSGNALATVIAAPLGSYLGSVIGW
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
RGAFFSLVPIALIALVWQWKSLPEMPVNARRAQSVRIFSLFRRRIVTLGMLASGMFFMGQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FALFTYVRPFLETVTRVDVSTLSLILLVIGITGFIGTALIGGVLKRSFYPTLIAIPVLMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAAALMIVGDRTTAVVVLLGSWGLLATAAPVGWWGWVARTFPDNAEAGGGLLVAIVQLA
HHHHHHHHHCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHH
IASGSTGGGLLFDSHGYRGTFLASVVLLLIAAFLTFLTSRSDTASAS
HHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1427017; 10984043 [H]