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The map label for this gene is tas8 [H]

Identifier: 189352495

GI number: 189352495

Start: 550187

End: 551176

Strand: Reverse

Name: tas8 [H]

Synonym: BMULJ_03715

Alternate gene names: 189352495

Gene position: 551176-550187 (Counterclockwise)

Preceding gene: 189352496

Following gene: 189352492

Centisome position: 22.29

GC content: 60.3

Gene sequence:

>990_bases
ATGGAATACAAGCATCTTGGACGAACAGGCCTGAAAATCAGCCGGCTCGCGCTCGGCACCATGAACTTCGGCGAACTGAC
CGATGAAGCCACCAGCTTTGCGATCATGGACGAAGCACTGGGCGCGGGCATCAACTTCTTTGATACCGCGGATGTCTATG
GCGGCCCACAGGCGCCGGATATGGACAAAGGCTACGGCGTTTCAGAAGATATCATCGGCCGTTGGCTCGCTCAGGGCGGT
GGCCGTCGCGAGCGGATCGTGCTCGCGACCAAGGTCTATCAGCCGATGGACACCGGGCCAAATGACCGGCGCCTGTCCGC
TTATCACATTCGTCGCGCGTGTGAGGCGAGCCTGCGCCGGCTCAAGACCGATCACATCGACCTCTACCAGATGCATCATG
TCGATCGCTTCACACCGTGGGACGAGATCTGGCAGGCGATGGAGACACTCATCCGCGACGGCAAAATCACCTATGTCGGC
AGCAGCAACTTCGCCGGCTGGCATATCGCGACGGCGCAATGCACGGCTGCGTCACGCAATTTACTGGGGCTTGCCTCCGA
GCAGAGTCTGTACAACCTGACGCAGCGCGCGATCGAACTGGAAGTGATCCCAGCTCTCCGGCACTTTGGTATTGGCCTCA
TTCCCTGGAGCCCAATCGGCATGGGCTTGCTCGGAGGTGTGCTGAAGAAGCTGGCCGACGGGAGACGAGCGACTGCGCAA
CTTCAGCAGCAGATTGACGAACTGCGTCCGCAGCTCGAAGCCTACGAAGCGCTGTGTGCACAGTTGAACGAGGCCCCATC
GGACGTTGCGCTTGCCTGGCTGCTTCACAACCCTGCAGTGACGGCTGCCATTAGCGGCCCACGGACGGTGGAGCAACTGC
GCCAAAACCTTAGGGCGCCGTCGCTTACGCTCTCGGCTGAAACACTTGCCAAGCTTGATGCGATCTGGCCAGGTCCCGGT
GGAGAAGCACCCGAGGCATATGCGTGGTAA

Upstream 100 bases:

>100_bases
GGCGATGTGAAATACCGCTTCGTCATTGACAGCTCGTCGCTGGCTCAGTGACCCATCGATTCAGACCGCGGATTCGTTTT
GAAACATCGGAGCTTGAGCT

Downstream 100 bases:

>100_bases
GGATGCAACATAGCGTCTAACGACGATACACGACTGGGCATATTTCGTCGGCATGCTCCGATTTCAAAGGGAAATTATCG
GTGTCAGCGGATTCCAGCGG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MEYKHLGRTGLKISRLALGTMNFGELTDEATSFAIMDEALGAGINFFDTADVYGGPQAPDMDKGYGVSEDIIGRWLAQGG
GRRERIVLATKVYQPMDTGPNDRRLSAYHIRRACEASLRRLKTDHIDLYQMHHVDRFTPWDEIWQAMETLIRDGKITYVG
SSNFAGWHIATAQCTAASRNLLGLASEQSLYNLTQRAIELEVIPALRHFGIGLIPWSPIGMGLLGGVLKKLADGRRATAQ
LQQQIDELRPQLEAYEALCAQLNEAPSDVALAWLLHNPAVTAAISGPRTVEQLRQNLRAPSLTLSAETLAKLDAIWPGPG
GEAPEAYAW

Sequences:

>Translated_329_residues
MEYKHLGRTGLKISRLALGTMNFGELTDEATSFAIMDEALGAGINFFDTADVYGGPQAPDMDKGYGVSEDIIGRWLAQGG
GRRERIVLATKVYQPMDTGPNDRRLSAYHIRRACEASLRRLKTDHIDLYQMHHVDRFTPWDEIWQAMETLIRDGKITYVG
SSNFAGWHIATAQCTAASRNLLGLASEQSLYNLTQRAIELEVIPALRHFGIGLIPWSPIGMGLLGGVLKKLADGRRATAQ
LQQQIDELRPQLEAYEALCAQLNEAPSDVALAWLLHNPAVTAAISGPRTVEQLRQNLRAPSLTLSAETLAKLDAIWPGPG
GEAPEAYAW
>Mature_329_residues
MEYKHLGRTGLKISRLALGTMNFGELTDEATSFAIMDEALGAGINFFDTADVYGGPQAPDMDKGYGVSEDIIGRWLAQGG
GRRERIVLATKVYQPMDTGPNDRRLSAYHIRRACEASLRRLKTDHIDLYQMHHVDRFTPWDEIWQAMETLIRDGKITYVG
SSNFAGWHIATAQCTAASRNLLGLASEQSLYNLTQRAIELEVIPALRHFGIGLIPWSPIGMGLLGGVLKKLADGRRATAQ
LQQQIDELRPQLEAYEALCAQLNEAPSDVALAWLLHNPAVTAAISGPRTVEQLRQNLRAPSLTLSAETLAKLDAIWPGPG
GEAPEAYAW

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=330, Percent_Identity=30, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI27436962, Length=330, Percent_Identity=30, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI27436966, Length=330, Percent_Identity=29.6969696969697, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI27436969, Length=330, Percent_Identity=30.6060606060606, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI4504825, Length=328, Percent_Identity=30.4878048780488, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI27436971, Length=330, Percent_Identity=29.3939393939394, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI41327764, Length=303, Percent_Identity=29.3729372937294, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI223718702, Length=303, Percent_Identity=27.7227722772277, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI41152114, Length=303, Percent_Identity=27.7227722772277, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI223718708, Length=163, Percent_Identity=30.6748466257669, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87081735, Length=333, Percent_Identity=35.4354354354354, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1789199, Length=352, Percent_Identity=30.6818181818182, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=27.8787878787879, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1788070, Length=332, Percent_Identity=30.421686746988, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788081, Length=333, Percent_Identity=28.5285285285285, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787674, Length=319, Percent_Identity=26.3322884012539, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994888, Length=308, Percent_Identity=25.3246753246753, Blast_Score=71, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=30.2670623145401, Blast_Score=145, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6319958, Length=313, Percent_Identity=27.4760383386581, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6323998, Length=330, Percent_Identity=26.6666666666667, Blast_Score=116, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6319951, Length=331, Percent_Identity=26.2839879154079, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6322615, Length=248, Percent_Identity=28.2258064516129, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24640980, Length=345, Percent_Identity=29.2753623188406, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI45549126, Length=345, Percent_Identity=29.2753623188406, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24646155, Length=318, Percent_Identity=26.1006289308176, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24646159, Length=266, Percent_Identity=27.0676691729323, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644950, Length=331, Percent_Identity=27.190332326284, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36206; Mature: 36206

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYKHLGRTGLKISRLALGTMNFGELTDEATSFAIMDEALGAGINFFDTADVYGGPQAPD
CCCCCCCCCCCEEHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
MDKGYGVSEDIIGRWLAQGGGRRERIVLATKVYQPMDTGPNDRRLSAYHIRRACEASLRR
CCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LKTDHIDLYQMHHVDRFTPWDEIWQAMETLIRDGKITYVGSSNFAGWHIATAQCTAASRN
HHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHCC
LLGLASEQSLYNLTQRAIELEVIPALRHFGIGLIPWSPIGMGLLGGVLKKLADGRRATAQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHH
LQQQIDELRPQLEAYEALCAQLNEAPSDVALAWLLHNPAVTAAISGPRTVEQLRQNLRAP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEHHHHCCCCEEEECCCCHHHHHHHHHCCCC
SLTLSAETLAKLDAIWPGPGGEAPEAYAW
CEEECHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEYKHLGRTGLKISRLALGTMNFGELTDEATSFAIMDEALGAGINFFDTADVYGGPQAPD
CCCCCCCCCCCEEHHHEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
MDKGYGVSEDIIGRWLAQGGGRRERIVLATKVYQPMDTGPNDRRLSAYHIRRACEASLRR
CCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LKTDHIDLYQMHHVDRFTPWDEIWQAMETLIRDGKITYVGSSNFAGWHIATAQCTAASRN
HHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHCC
LLGLASEQSLYNLTQRAIELEVIPALRHFGIGLIPWSPIGMGLLGGVLKKLADGRRATAQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHH
LQQQIDELRPQLEAYEALCAQLNEAPSDVALAWLLHNPAVTAAISGPRTVEQLRQNLRAP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEHHHHCCCCEEEECCCCHHHHHHHHHCCCC
SLTLSAETLAKLDAIWPGPGGEAPEAYAW
CEEECHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]