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The map label for this gene is thrB [H]

Identifier: 189352418

GI number: 189352418

Start: 474378

End: 475376

Strand: Reverse

Name: thrB [H]

Synonym: BMULJ_03637

Alternate gene names: 189352418

Gene position: 475376-474378 (Counterclockwise)

Preceding gene: 189352419

Following gene: 189352417

Centisome position: 19.22

GC content: 68.27

Gene sequence:

>999_bases
ATGGCCGTTTTCACCGCTGTTTCCGACTCCGATCTCGCGCAATGGATGCGCCACTACGCACTGGGCGACGTCGTTGCGTT
CCGCGGCATTCCGTCCGGCATCGAGAACAGCAACTTCTTCCTGACGACGACGCGCGGCGAGTACGTGCTGACGATCTTCG
AAAAGCTGACGGCCGAGCAGTTGCCGTTCTACCTCGACCTGATGCGCCATCTCGCCGGCCACGGCGTGCCGGTCCCCGAT
CCGGTGCCGCGCGACGACGGCGCGCTGTTCGGCACGCTGCACGGCAAGCCGGCGGCAATCGTCACGAAGCTCGACGGTGC
GGCCGAACTCGCGCCGGGGGTCGAACACTGCATCGAGGTCGGCCAGATGCTCGCGCGCATGCATCTGGCGGGGCGCGACT
ATCCGCGCCGGCAGCCGAACCTGCGCAGCCTGCCGTGGTGGCAGGAGAACGTGCCGGCGATCGTGCCGTTCGTGACCGAC
GCGCAGCGCGCGCTGCTCGAAGGCGAACTCGCGCATCAGGCGCGCTTCTTCGGCTCTGAAGACTACGCGGCGCTGCCGGG
CGGCCCGTGCCACTGCGATCTGTTCCGCGACAACGTGCTGTTCGCGCACGCGGCGCCCGACACGGGCCACGCGGTGCGGC
TCGGCGGCTTCTTCGACTTCTATTTCGCCGGCTGCGACAAGTGGCTGTTCGACGTCGCGGTCACGGTCAACGACTGGTGC
GTCGACCTCGCGACCGGCGTGCTCGACACCGCGCGCGCCGACGCGCTGCTGCGCGCATACCAGACGGTCCGGCCGTTCAC
GGCCGAGGAGCGCCGTCACTGGAGCGACATGCTGCGCGCCGGCGCGTACCGCTTCTGGGTGTCGCGCCTGTACGACTTCT
ACCTGCCGCGTGCGGCCGAGATGCTGAAGCCGCACGATCCCGGCCATTTCGAACGCATTCTGCGCGAGCGTATCGCCCAT
ACGCCCGCGCTTCCCGAGATCCAAACCGCATGCAACTGA

Upstream 100 bases:

>100_bases
GCCGCGCCGCGTCGCTCCCGGCACGGCGCGCCCGCCTCTCTCCACTCCCGTCGCGACGCGCGCACTGCGCGCGCCGGCAC
ACTGACCACACGCATCTCGC

Downstream 100 bases:

>100_bases
TCGAAGTGCCCGCGAAAACGGGCTATGTCTGGTTCCGACAAGGCATCTGGCTGTTCCGCCGGAATCCGCTCGCGTTCATC
ACGCTGTTCTTCACCTACCT

Product: homoserine kinase

Products: NA

Alternate protein names: HK; HSK [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MAVFTAVSDSDLAQWMRHYALGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFEKLTAEQLPFYLDLMRHLAGHGVPVPD
PVPRDDGALFGTLHGKPAAIVTKLDGAAELAPGVEHCIEVGQMLARMHLAGRDYPRRQPNLRSLPWWQENVPAIVPFVTD
AQRALLEGELAHQARFFGSEDYAALPGGPCHCDLFRDNVLFAHAAPDTGHAVRLGGFFDFYFAGCDKWLFDVAVTVNDWC
VDLATGVLDTARADALLRAYQTVRPFTAEERRHWSDMLRAGAYRFWVSRLYDFYLPRAAEMLKPHDPGHFERILRERIAH
TPALPEIQTACN

Sequences:

>Translated_332_residues
MAVFTAVSDSDLAQWMRHYALGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFEKLTAEQLPFYLDLMRHLAGHGVPVPD
PVPRDDGALFGTLHGKPAAIVTKLDGAAELAPGVEHCIEVGQMLARMHLAGRDYPRRQPNLRSLPWWQENVPAIVPFVTD
AQRALLEGELAHQARFFGSEDYAALPGGPCHCDLFRDNVLFAHAAPDTGHAVRLGGFFDFYFAGCDKWLFDVAVTVNDWC
VDLATGVLDTARADALLRAYQTVRPFTAEERRHWSDMLRAGAYRFWVSRLYDFYLPRAAEMLKPHDPGHFERILRERIAH
TPALPEIQTACN
>Mature_331_residues
AVFTAVSDSDLAQWMRHYALGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFEKLTAEQLPFYLDLMRHLAGHGVPVPDP
VPRDDGALFGTLHGKPAAIVTKLDGAAELAPGVEHCIEVGQMLARMHLAGRDYPRRQPNLRSLPWWQENVPAIVPFVTDA
QRALLEGELAHQARFFGSEDYAALPGGPCHCDLFRDNVLFAHAAPDTGHAVRLGGFFDFYFAGCDKWLFDVAVTVNDWCV
DLATGVLDTARADALLRAYQTVRPFTAEERRHWSDMLRAGAYRFWVSRLYDFYLPRAAEMLKPHDPGHFERILRERIAHT
PALPEIQTACN

Specific function: Unknown

COG id: COG2334

COG function: function code R; Putative homoserine kinase type II (protein kinase fold)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudomonas-type thrB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002575
- InterPro:   IPR005280
- InterPro:   IPR011009 [H]

Pfam domain/function: PF01636 APH [H]

EC number: =2.7.1.39 [H]

Molecular weight: Translated: 37207; Mature: 37076

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFTAVSDSDLAQWMRHYALGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFEKLTAEQ
CEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
LPFYLDLMRHLAGHGVPVPDPVPRDDGALFGTLHGKPAAIVTKLDGAAELAPGVEHCIEV
CCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCHHHHCHHHHHHHHH
GQMLARMHLAGRDYPRRQPNLRSLPWWQENVPAIVPFVTDAQRALLEGELAHQARFFGSE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCC
DYAALPGGPCHCDLFRDNVLFAHAAPDTGHAVRLGGFFDFYFAGCDKWLFDVAVTVNDWC
CCCCCCCCCEEEEEECCCEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
VDLATGVLDTARADALLRAYQTVRPFTAEERRHWSDMLRAGAYRFWVSRLYDFYLPRAAE
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLKPHDPGHFERILRERIAHTPALPEIQTACN
HCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCC
>Mature Secondary Structure 
AVFTAVSDSDLAQWMRHYALGDVVAFRGIPSGIENSNFFLTTTRGEYVLTIFEKLTAEQ
EEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
LPFYLDLMRHLAGHGVPVPDPVPRDDGALFGTLHGKPAAIVTKLDGAAELAPGVEHCIEV
CCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCHHHHCHHHHHHHHH
GQMLARMHLAGRDYPRRQPNLRSLPWWQENVPAIVPFVTDAQRALLEGELAHQARFFGSE
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCC
DYAALPGGPCHCDLFRDNVLFAHAAPDTGHAVRLGGFFDFYFAGCDKWLFDVAVTVNDWC
CCCCCCCCCEEEEEECCCEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
VDLATGVLDTARADALLRAYQTVRPFTAEERRHWSDMLRAGAYRFWVSRLYDFYLPRAAE
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLKPHDPGHFERILRERIAHTPALPEIQTACN
HCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA