Click here to switch to the map view.

The map label for this gene is pphA [H]

Identifier: 189352397

GI number: 189352397

Start: 454631

End: 455362

Strand: Reverse

Name: pphA [H]

Synonym: BMULJ_03616

Alternate gene names: 189352397

Gene position: 455362-454631 (Counterclockwise)

Preceding gene: 189352399

Following gene: 189352394

Centisome position: 18.41

GC content: 72.27

Gene sequence:

>732_bases
ATGAGCGCTTCCGCCCTCCTCCATCGTCATCCGGCCAACGTCGCGGGCCGCGACTTCGTCGTCGGCGATCTGCACGGCTG
CGTCGATGCGCTGCGCGCACTGCTGCGCGAGGTGCGCTTCGATCCGGCGCGCGACCGGCTGTTCTCGGTCGGCGATCTCG
TCGACCGCGGGCCGGCATCCGAAACCGCGCTCGAGCTGCTCGATCGCCCGTGGTGTCACGTCGTGCGCGGCAATCACGAA
GAAGTGCTGAGCCTCGTCGCGCGCGGCAAGCTGCCGGCCGACGCATGGCGCGGCATCGGCGGCGACTGGGGCGCCGATCT
GCCGCCCGAGCGGCTGCGCGCGTACGCGGCGCGCGTCGACGCGCTGCCGCTCGTGCGCGTGATCGGCGAAGGCGCGACGC
GCTTCAACGTGCTGCATGCGGAATTCTTCGGCTCGGACGCCGATCTAGATACCGGCGACTATCCGCCCGACGTGCGCGAG
CGGCTGATCTGGGGCCGCGATCTCGTGCAGGGACTCGTCGATCCGGGCTGGCAGGCCGGCCTGTCGCTGACCTGCAGCGG
CCATACGCCGGTGCGCGTGCCGCAGCGGATCGGCGCGCAATGGTTCATCGATACGGGTGCGTTCGCACCGGCCGGCCGGC
TGACGCTCGCCGAGCCGCGCACGGGACAGACGTGGTCGATCACGCAGGCCGCCGCACGCGAACGCGGAGCGGCCGCGTGG
CCGCTGCCGTGA

Upstream 100 bases:

>100_bases
CTCCGGCACGACGAAACGACGCTCCTTACTTCCCGCGCTACGATCGATCTTCGGCACTCGCATGGGCGTTGGACCTGCAA
ACACGCCCTAAGATAAAGGC

Downstream 100 bases:

>100_bases
GACTCACAGGGCGGACCGCAGAACGACCGTCCGGCCGGACGCCGACACCGCATCGAATGCACGGGCGGCGCGACGCCCGC
GCATGCTCGCACCTACCCGA

Product: serine/threonine protein phosphatase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSASALLHRHPANVAGRDFVVGDLHGCVDALRALLREVRFDPARDRLFSVGDLVDRGPASETALELLDRPWCHVVRGNHE
EVLSLVARGKLPADAWRGIGGDWGADLPPERLRAYAARVDALPLVRVIGEGATRFNVLHAEFFGSDADLDTGDYPPDVRE
RLIWGRDLVQGLVDPGWQAGLSLTCSGHTPVRVPQRIGAQWFIDTGAFAPAGRLTLAEPRTGQTWSITQAAARERGAAAW
PLP

Sequences:

>Translated_243_residues
MSASALLHRHPANVAGRDFVVGDLHGCVDALRALLREVRFDPARDRLFSVGDLVDRGPASETALELLDRPWCHVVRGNHE
EVLSLVARGKLPADAWRGIGGDWGADLPPERLRAYAARVDALPLVRVIGEGATRFNVLHAEFFGSDADLDTGDYPPDVRE
RLIWGRDLVQGLVDPGWQAGLSLTCSGHTPVRVPQRIGAQWFIDTGAFAPAGRLTLAEPRTGQTWSITQAAARERGAAAW
PLP
>Mature_242_residues
SASALLHRHPANVAGRDFVVGDLHGCVDALRALLREVRFDPARDRLFSVGDLVDRGPASETALELLDRPWCHVVRGNHEE
VLSLVARGKLPADAWRGIGGDWGADLPPERLRAYAARVDALPLVRVIGEGATRFNVLHAEFFGSDADLDTGDYPPDVRER
LIWGRDLVQGLVDPGWQAGLSLTCSGHTPVRVPQRIGAQWFIDTGAFAPAGRLTLAEPRTGQTWSITQAAARERGAAAWP
LP

Specific function: Can hydrolyze phosphorylated Ser-, Thr- or Tyr- substrates in vitro. The natural substrate is unknown [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPP phosphatase family. PP-1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081988, Length=211, Percent_Identity=33.6492890995261, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1789090, Length=207, Percent_Identity=31.8840579710145, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 26411; Mature: 26280

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00125 SER_THR_PHOSPHATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASALLHRHPANVAGRDFVVGDLHGCVDALRALLREVRFDPARDRLFSVGDLVDRGPAS
CCCCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCH
ETALELLDRPWCHVVRGNHEEVLSLVARGKLPADAWRGIGGDWGADLPPERLRAYAARVD
HHHHHHHCCCCCEECCCCHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ALPLVRVIGEGATRFNVLHAEFFGSDADLDTGDYPPDVRERLIWGRDLVQGLVDPGWQAG
HHHHHHHHCCCCHHHEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
LSLTCSGHTPVRVPQRIGAQWFIDTGAFAPAGRLTLAEPRTGQTWSITQAAARERGAAAW
EEEEECCCCCCCCHHHCCCEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCCC
PLP
CCC
>Mature Secondary Structure 
SASALLHRHPANVAGRDFVVGDLHGCVDALRALLREVRFDPARDRLFSVGDLVDRGPAS
CCCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCH
ETALELLDRPWCHVVRGNHEEVLSLVARGKLPADAWRGIGGDWGADLPPERLRAYAARVD
HHHHHHHCCCCCEECCCCHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ALPLVRVIGEGATRFNVLHAEFFGSDADLDTGDYPPDVRERLIWGRDLVQGLVDPGWQAG
HHHHHHHHCCCCHHHEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
LSLTCSGHTPVRVPQRIGAQWFIDTGAFAPAGRLTLAEPRTGQTWSITQAAARERGAAAW
EEEEECCCCCCCCHHHCCCEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCCC
PLP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11717262; 11677609 [H]