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The map label for this gene is ttdR [H]

Identifier: 189352271

GI number: 189352271

Start: 316495

End: 317403

Strand: Reverse

Name: ttdR [H]

Synonym: BMULJ_03490

Alternate gene names: 189352271

Gene position: 317403-316495 (Counterclockwise)

Preceding gene: 189352277

Following gene: 189352267

Centisome position: 12.83

GC content: 68.76

Gene sequence:

>909_bases
ATGACGGACACCGTGCAGCCGGCCGATCTCGCCTTCTTCTCGACGCTGGCCGCGTCGGGCAGCCTCAGTGCGGCCGCGCG
CGAACTCGGACTGACGGCGGCGGCCGTCAGCAAGCGGCTCACGCAGATGGAGCGGCGCGCGGGCGTCACGCTCGTCAACC
GGACGACGCGTCGCATGATGCTGACGCCCGAAGGCGACGTGTATCTCGACTACGCGCGCCGCATCCTCGATCAGATGGAC
GAGCTCGGCGAACTGCTCGGCAGCGCGAAGCAGCGGCCGAAGGGGCTGCTGCGCGTGAACGCCACGCTCGGCTTCGGGCG
CAGCCATGTCGGTCCGGCGATCTCGCGGTTCGTCGCGCGCTATCCGGAGGTGTCGGTGCAACTGCAGCTGTCGGTGATGC
CGCCGCCGCTCACCGACGACGCGTTCGACGTCTGCATCCGCTTCGGCGAGCCGCCTGACACGCGTGTCGTCGCGCGGCGG
CTTGCGCCGAACCGCCGGCTGCTGTGCGCGGCGCCCGCGTATCTCGCGCGGCACGGCACACCGGGCACGCCGCATGAACT
GACACGGCACAACTGCATCGGCATCCGGCAAGGCGACGAGAACTACGGAATCTGGCGGCTGACGACGGGCCGCGGCGCGG
CCCGTCATACCGAAGCCGTGCGGATCAACGGCAATCTGACGACGAACGACGGCGAAATCGCAGTGAAGTGGGCACTCGAC
GGGCACGGCATCCTGATGCGTGCCGAGTGGGACATCCGCGACTATCTGGCCGACGGGCGCCTCGTCGTCGTGCTGCAGGA
CTACGAAACGCCGAGCGCGGACATCTATGCGGTGTATGCCCAGCGCCATCAGATGTCGACGCGGATCCGCGCGTTCGTCG
ATTTTCTCGCGGCAGAACTGGGCGGCTGA

Upstream 100 bases:

>100_bases
CCTCGATTGATCGTGAGCGTACGGCCACTTTACCGAACCGACAGTGCAGGAACCGGTGCTAGACTCAAAGCATCTTTAAC
TTCCGTTCACGAATCGCGTC

Downstream 100 bases:

>100_bases
CGACAGCATGGTCCGCGCGGCGCAAGGGTCGCTTATGCGGGCGCGGCCGCGGGCGCGCTTCGGCAGCGTCGCGTCGAACC
GAATGCAATGCGCGGCATCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTDTVQPADLAFFSTLAASGSLSAAARELGLTAAAVSKRLTQMERRAGVTLVNRTTRRMMLTPEGDVYLDYARRILDQMD
ELGELLGSAKQRPKGLLRVNATLGFGRSHVGPAISRFVARYPEVSVQLQLSVMPPPLTDDAFDVCIRFGEPPDTRVVARR
LAPNRRLLCAAPAYLARHGTPGTPHELTRHNCIGIRQGDENYGIWRLTTGRGAARHTEAVRINGNLTTNDGEIAVKWALD
GHGILMRAEWDIRDYLADGRLVVVLQDYETPSADIYAVYAQRHQMSTRIRAFVDFLAAELGG

Sequences:

>Translated_302_residues
MTDTVQPADLAFFSTLAASGSLSAAARELGLTAAAVSKRLTQMERRAGVTLVNRTTRRMMLTPEGDVYLDYARRILDQMD
ELGELLGSAKQRPKGLLRVNATLGFGRSHVGPAISRFVARYPEVSVQLQLSVMPPPLTDDAFDVCIRFGEPPDTRVVARR
LAPNRRLLCAAPAYLARHGTPGTPHELTRHNCIGIRQGDENYGIWRLTTGRGAARHTEAVRINGNLTTNDGEIAVKWALD
GHGILMRAEWDIRDYLADGRLVVVLQDYETPSADIYAVYAQRHQMSTRIRAFVDFLAAELGG
>Mature_301_residues
TDTVQPADLAFFSTLAASGSLSAAARELGLTAAAVSKRLTQMERRAGVTLVNRTTRRMMLTPEGDVYLDYARRILDQMDE
LGELLGSAKQRPKGLLRVNATLGFGRSHVGPAISRFVARYPEVSVQLQLSVMPPPLTDDAFDVCIRFGEPPDTRVVARRL
APNRRLLCAAPAYLARHGTPGTPHELTRHNCIGIRQGDENYGIWRLTTGRGAARHTEAVRINGNLTTNDGEIAVKWALDG
HGILMRAEWDIRDYLADGRLVVVLQDYETPSADIYAVYAQRHQMSTRIRAFVDFLAAELGG

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=290, Percent_Identity=39.3103448275862, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=36.4583333333333, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=34.1379310344828, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=31.4878892733564, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1789639, Length=290, Percent_Identity=27.2413793103448, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=28.9655172413793, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1787589, Length=293, Percent_Identity=25.938566552901, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790011, Length=303, Percent_Identity=27.0627062706271, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786448, Length=292, Percent_Identity=23.972602739726, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788706, Length=297, Percent_Identity=25.5892255892256, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI157672245, Length=141, Percent_Identity=31.9148936170213, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789173, Length=303, Percent_Identity=25.4125412541254, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33282; Mature: 33151

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTVQPADLAFFSTLAASGSLSAAARELGLTAAAVSKRLTQMERRAGVTLVNRTTRRMM
CCCCCCCHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEECCCEEEE
LTPEGDVYLDYARRILDQMDELGELLGSAKQRPKGLLRVNATLGFGRSHVGPAISRFVAR
ECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHCCHHHHHHHHH
YPEVSVQLQLSVMPPPLTDDAFDVCIRFGEPPDTRVVARRLAPNRRLLCAAPAYLARHGT
CCCEEEEEEEEECCCCCCCCHHHHHEECCCCCCHHHHHHHHCCCCEEEEECCHHHHHCCC
PGTPHELTRHNCIGIRQGDENYGIWRLTTGRGAARHTEAVRINGNLTTNDGEIAVKWALD
CCCCHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCEEEEECCEEECCCCCEEEEEEEC
GHGILMRAEWDIRDYLADGRLVVVLQDYETPSADIYAVYAQRHQMSTRIRAFVDFLAAEL
CCEEEEEECCCHHHHHCCCEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
GG
CC
>Mature Secondary Structure 
TDTVQPADLAFFSTLAASGSLSAAARELGLTAAAVSKRLTQMERRAGVTLVNRTTRRMM
CCCCCCHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEECCCEEEE
LTPEGDVYLDYARRILDQMDELGELLGSAKQRPKGLLRVNATLGFGRSHVGPAISRFVAR
ECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHCCHHHHHHHHH
YPEVSVQLQLSVMPPPLTDDAFDVCIRFGEPPDTRVVARRLAPNRRLLCAAPAYLARHGT
CCCEEEEEEEEECCCCCCCCHHHHHEECCCCCCHHHHHHHHCCCCEEEEECCHHHHHCCC
PGTPHELTRHNCIGIRQGDENYGIWRLTTGRGAARHTEAVRINGNLTTNDGEIAVKWALD
CCCCHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCEEEEECCEEECCCCCEEEEEEEC
GHGILMRAEWDIRDYLADGRLVVVLQDYETPSADIYAVYAQRHQMSTRIRAFVDFLAAEL
CCEEEEEECCCHHHHHCCCEEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
GG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]