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The map label for this gene is glmS [H]

Identifier: 189352130

GI number: 189352130

Start: 155726

End: 157555

Strand: Reverse

Name: glmS [H]

Synonym: BMULJ_03348

Alternate gene names: 189352130

Gene position: 157555-155726 (Counterclockwise)

Preceding gene: 189352132

Following gene: 189352129

Centisome position: 6.37

GC content: 66.5

Gene sequence:

>1830_bases
ATGTGTGGAATTGTCGGGGCGGTGGCCCAGCGGGACATCCTGCCGAACCTCGTCGACGGCCTGACGCGGCTCGAGTACCG
CGGCTACGACTCGTGCGGCGTCGTGGTCTATCGCGACCGCGCGCTGGCGCGGGCGCGCAGCGTCGATCGCGTCGCCAACC
TGCAGCGCGACATCGCCGCGCAGGCGCTGTCCGGCTACACCGGCATCGCGCATACGCGCTGGGCGACGCACGGCGCGCCC
GTCACGCAGAACGCGCATCCGCATTTCTCGCCGAGCGACACCGACGCACGCATCGCGCTGTCGCACAACGGGATCATCGA
GAACTGCGATCAACTGCGTGCGGAACTCGAAGCGCACGGCTACGTGTTCGCGAGCCAGACCGACAGCGAAGCGATCGCGC
ATCTGATCGACCATCTGTACGACGGCGATCTGTTCGATGCCGTGCAGCGCGCCGCCGCGCGTCTGCGCGGCAGCTACGCG
ATTGCGGTGATGTGCCGCGACGAGCCGCACCGGATCGTCGGCGCGCGCGACGGGATGCCGCTCGTCGTCGGCGTCGGCGA
CGGCGAGAACTTCCTCGCGTCCGATGCGATCGCGCTGTCGGGCATCACCGATCGCATCGCGTATCTGGAGAACGGCGACG
TCGCCGATATCCAGCTGCATCGCTACTGGATCGTCGACGCCGCCGGGCAGCGCGTCGAACGCGCGGTGCAGCGGGTGGCT
GCGCACAGCGGCGCGGCCGATCTCGGCTCGTATCGCTACTACATGCAGAAGGAGATTTTCGAGCAGCCGCAGGCCGTCGC
GGACACGTTGCTCGATGTCACGTCGATCATGCCCGAGCTGTTCGGCGACGGCGCATGGCGCGTGTTCAACGACGTCGATT
CGGTGCTGCTGCTCGCCTGCGGCGGCAGCTACCACGCGGCGCTCACCGCGAAATACTGGATCGAGAGCATCGCAAAGCTG
CCGACCAACGTCGAGATCGCGAGCGAATTCCGCTATCGCGACAACGTGCCGAATCCGCGCACGCTCGTCGTGGCGGTATC
TCAGAGCGGCGAGACGGCCGACGTGCTGGGCGCGGTACACGTCGCGAAGCAGCGCGGGATGATGCAGACGCTTGCGATCT
GCAATGTCGCGACAAGTGCGCTGATGCGCGAATGCGCGCTGCAGTTCGTCACGCGGGCGGGGATCGAGATCGGCGTCGCA
TCGACGAAGGCGTTCACGACACAGCTCGTCGCGCTGTTCCTGCTGACGCTGTCGCTCGCGCAGGTGCGCGGGCGCCTGAG
CGAAGACGACGAGCACGCGCATCTGCGCGCGCTGCGCCACCTGCCCGACGCGATGTCGAAGGTGCTCGCGCTGGAGCCGC
AGATCATGGGCTGGTCGGAACTGCTCGCGCGGCGCGACGACATGCTGTTCCTCGGACGCGGGATGCACTACCCGATCGCG
CTCGAGGGCGCGCTGAAGATGAAGGAGATTTCGTATATCCACGCGGAGGCGTATCCGGCCGGCGAGCTCAAGCACGGGCC
GCTCGCGCTCGTCAGCAACGAGATGCCGGTGATCGCGGTCGCGCCGAACGACATGTTGCTCGAGAAGCTGCGGTCGAACA
TGCACGAGGTCAGCGCGCGCAACGGGAAGCTGTACGTGTTCGCGGACGTGGATTGCGGGTTGTCGCCGAGCGAGGGGATC
GAGGTGATTCGGCTCAATGAGTACTATGGGCCGCTGTCGCCGATCCTGCATACGATTCCGATGCAACTGCTCGCTTATCA
CGCGGCGCTGGCGAGAGGGACGGATATCGATAAGCCGAGGAATTTGGCGAAGTCGGTGACGGTGGAGTGA

Upstream 100 bases:

>100_bases
CATGCCATTTCATTTTCACCAGTATTTTGAAATTTAATTCCACGAGGTCGCCCCTACCATCGCTGTCACGGATTCAGACA
CGACTTTTTGGGAGCGCGAT

Downstream 100 bases:

>100_bases
GGGGGACAGTAACACTCTCGACAGTGCTGTCTCTCTACGCTGCATCGTGGATGTTGACCGTTGCCTCTTTCTGAGAGTGC
TCCGTACTTGCCTTTACTCC

Product: glucosamine-fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MCGIVGAVAQRDILPNLVDGLTRLEYRGYDSCGVVVYRDRALARARSVDRVANLQRDIAAQALSGYTGIAHTRWATHGAP
VTQNAHPHFSPSDTDARIALSHNGIIENCDQLRAELEAHGYVFASQTDSEAIAHLIDHLYDGDLFDAVQRAAARLRGSYA
IAVMCRDEPHRIVGARDGMPLVVGVGDGENFLASDAIALSGITDRIAYLENGDVADIQLHRYWIVDAAGQRVERAVQRVA
AHSGAADLGSYRYYMQKEIFEQPQAVADTLLDVTSIMPELFGDGAWRVFNDVDSVLLLACGGSYHAALTAKYWIESIAKL
PTNVEIASEFRYRDNVPNPRTLVVAVSQSGETADVLGAVHVAKQRGMMQTLAICNVATSALMRECALQFVTRAGIEIGVA
STKAFTTQLVALFLLTLSLAQVRGRLSEDDEHAHLRALRHLPDAMSKVLALEPQIMGWSELLARRDDMLFLGRGMHYPIA
LEGALKMKEISYIHAEAYPAGELKHGPLALVSNEMPVIAVAPNDMLLEKLRSNMHEVSARNGKLYVFADVDCGLSPSEGI
EVIRLNEYYGPLSPILHTIPMQLLAYHAALARGTDIDKPRNLAKSVTVE

Sequences:

>Translated_609_residues
MCGIVGAVAQRDILPNLVDGLTRLEYRGYDSCGVVVYRDRALARARSVDRVANLQRDIAAQALSGYTGIAHTRWATHGAP
VTQNAHPHFSPSDTDARIALSHNGIIENCDQLRAELEAHGYVFASQTDSEAIAHLIDHLYDGDLFDAVQRAAARLRGSYA
IAVMCRDEPHRIVGARDGMPLVVGVGDGENFLASDAIALSGITDRIAYLENGDVADIQLHRYWIVDAAGQRVERAVQRVA
AHSGAADLGSYRYYMQKEIFEQPQAVADTLLDVTSIMPELFGDGAWRVFNDVDSVLLLACGGSYHAALTAKYWIESIAKL
PTNVEIASEFRYRDNVPNPRTLVVAVSQSGETADVLGAVHVAKQRGMMQTLAICNVATSALMRECALQFVTRAGIEIGVA
STKAFTTQLVALFLLTLSLAQVRGRLSEDDEHAHLRALRHLPDAMSKVLALEPQIMGWSELLARRDDMLFLGRGMHYPIA
LEGALKMKEISYIHAEAYPAGELKHGPLALVSNEMPVIAVAPNDMLLEKLRSNMHEVSARNGKLYVFADVDCGLSPSEGI
EVIRLNEYYGPLSPILHTIPMQLLAYHAALARGTDIDKPRNLAKSVTVE
>Mature_609_residues
MCGIVGAVAQRDILPNLVDGLTRLEYRGYDSCGVVVYRDRALARARSVDRVANLQRDIAAQALSGYTGIAHTRWATHGAP
VTQNAHPHFSPSDTDARIALSHNGIIENCDQLRAELEAHGYVFASQTDSEAIAHLIDHLYDGDLFDAVQRAAARLRGSYA
IAVMCRDEPHRIVGARDGMPLVVGVGDGENFLASDAIALSGITDRIAYLENGDVADIQLHRYWIVDAAGQRVERAVQRVA
AHSGAADLGSYRYYMQKEIFEQPQAVADTLLDVTSIMPELFGDGAWRVFNDVDSVLLLACGGSYHAALTAKYWIESIAKL
PTNVEIASEFRYRDNVPNPRTLVVAVSQSGETADVLGAVHVAKQRGMMQTLAICNVATSALMRECALQFVTRAGIEIGVA
STKAFTTQLVALFLLTLSLAQVRGRLSEDDEHAHLRALRHLPDAMSKVLALEPQIMGWSELLARRDDMLFLGRGMHYPIA
LEGALKMKEISYIHAEAYPAGELKHGPLALVSNEMPVIAVAPNDMLLEKLRSNMHEVSARNGKLYVFADVDCGLSPSEGI
EVIRLNEYYGPLSPILHTIPMQLLAYHAALARGTDIDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=688, Percent_Identity=35.3197674418605, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI205277386, Length=686, Percent_Identity=35.7142857142857, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI29570798, Length=201, Percent_Identity=27.8606965174129, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1790167, Length=616, Percent_Identity=50.3246753246753, Blast_Score=584, Evalue=1e-168,
Organism=Escherichia coli, GI87082251, Length=321, Percent_Identity=23.0529595015576, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788651, Length=218, Percent_Identity=29.3577981651376, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17539970, Length=718, Percent_Identity=31.7548746518106, Blast_Score=332, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI17532899, Length=430, Percent_Identity=35.8139534883721, Blast_Score=257, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17532897, Length=430, Percent_Identity=35.8139534883721, Blast_Score=257, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6322745, Length=457, Percent_Identity=36.5426695842451, Blast_Score=254, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6323731, Length=430, Percent_Identity=29.3023255813954, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6323730, Length=207, Percent_Identity=35.7487922705314, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21357745, Length=691, Percent_Identity=34.2981186685962, Blast_Score=353, Evalue=2e-97,
Organism=Drosophila melanogaster, GI28573187, Length=257, Percent_Identity=27.2373540856031, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24659598, Length=199, Percent_Identity=29.6482412060301, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24659604, Length=175, Percent_Identity=29.7142857142857, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 66522; Mature: 66522

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRDILPNLVDGLTRLEYRGYDSCGVVVYRDRALARARSVDRVANLQRDIAA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
QALSGYTGIAHTRWATHGAPVTQNAHPHFSPSDTDARIALSHNGIIENCDQLRAELEAHG
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCC
YVFASQTDSEAIAHLIDHLYDGDLFDAVQRAAARLRGSYAIAVMCRDEPHRIVGARDGMP
EEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCE
LVVGVGDGENFLASDAIALSGITDRIAYLENGDVADIQLHRYWIVDAAGQRVERAVQRVA
EEEEECCCCCHHHHCHHHHCCHHHHHHEECCCCEEEEEEEEEEEEEHHHHHHHHHHHHHH
AHSGAADLGSYRYYMQKEIFEQPQAVADTLLDVTSIMPELFGDGAWRVFNDVDSVLLLAC
HCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEE
GGSYHAALTAKYWIESIAKLPTNVEIASEFRYRDNVPNPRTLVVAVSQSGETADVLGAVH
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHH
VAKQRGMMQTLAICNVATSALMRECALQFVTRAGIEIGVASTKAFTTQLVALFLLTLSLA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHH
QVRGRLSEDDEHAHLRALRHLPDAMSKVLALEPQIMGWSELLARRDDMLFLGRGMHYPIA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCCCCCCEE
LEGALKMKEISYIHAEAYPAGELKHGPLALVSNEMPVIAVAPNDMLLEKLRSNMHEVSAR
ECCCHHHHHHHEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCC
NGKLYVFADVDCGLSPSEGIEVIRLNEYYGPLSPILHTIPMQLLAYHAALARGTDIDKPR
CCEEEEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
NLAKSVTVE
HHHHHCCCC
>Mature Secondary Structure
MCGIVGAVAQRDILPNLVDGLTRLEYRGYDSCGVVVYRDRALARARSVDRVANLQRDIAA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
QALSGYTGIAHTRWATHGAPVTQNAHPHFSPSDTDARIALSHNGIIENCDQLRAELEAHG
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCC
YVFASQTDSEAIAHLIDHLYDGDLFDAVQRAAARLRGSYAIAVMCRDEPHRIVGARDGMP
EEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCCE
LVVGVGDGENFLASDAIALSGITDRIAYLENGDVADIQLHRYWIVDAAGQRVERAVQRVA
EEEEECCCCCHHHHCHHHHCCHHHHHHEECCCCEEEEEEEEEEEEEHHHHHHHHHHHHHH
AHSGAADLGSYRYYMQKEIFEQPQAVADTLLDVTSIMPELFGDGAWRVFNDVDSVLLLAC
HCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEE
GGSYHAALTAKYWIESIAKLPTNVEIASEFRYRDNVPNPRTLVVAVSQSGETADVLGAVH
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHH
VAKQRGMMQTLAICNVATSALMRECALQFVTRAGIEIGVASTKAFTTQLVALFLLTLSLA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHH
QVRGRLSEDDEHAHLRALRHLPDAMSKVLALEPQIMGWSELLARRDDMLFLGRGMHYPIA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEECCCCCCCEE
LEGALKMKEISYIHAEAYPAGELKHGPLALVSNEMPVIAVAPNDMLLEKLRSNMHEVSAR
ECCCHHHHHHHEEEECCCCCCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCC
NGKLYVFADVDCGLSPSEGIEVIRLNEYYGPLSPILHTIPMQLLAYHAALARGTDIDKPR
CCEEEEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
NLAKSVTVE
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]