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The map label for this gene is luxQ [H]

Identifier: 189352080

GI number: 189352080

Start: 96426

End: 98231

Strand: Reverse

Name: luxQ [H]

Synonym: BMULJ_03297

Alternate gene names: 189352080

Gene position: 98231-96426 (Counterclockwise)

Preceding gene: 189352081

Following gene: 189352077

Centisome position: 3.97

GC content: 68.55

Gene sequence:

>1806_bases
ATGACACGCCGCCGATGGCGTAACCGGAAGGTCATCCTCGTTCTCGGCTCGGTCTGGCTGCTCGGGTTCGCCGCGTGGGC
GTTCCTGCTGTGGGACCTGCTCGCGACGTCGGTCAACGAAGGCGTGCTCGAAGGGCCGCGCGAGGGCGTGTTCTGGACGG
CCGCGCAATACCGCAACGTCTATACGCGCTTCAACCGCCAGCTGATCCTCTACGCCACGCATCAGGACGACGACTTCGAC
AAGCTGCAGATGCAGCTCGACAGCCTCTCCGTGTCGTTCGGCTTTCTCGAGCGGCCGTCCGAAGTGTCCGAATACTGGCT
GCGCATCCCGAGCGCGCGCGGCGAGATCGCGACACTCGGCGCCTTCATGGCGCAACTGAAGCGCGACGTGCCGAAGCTGC
GCGACGCGCCGCAGCAAGCGCCGCGCGTGCTGGCCGACGTCGACGCATACTGGCCGCGCGTCAACGGTCTCGCGAACGAC
TTCCGCGCAATCGAAATGGCGCAGCGCGACTTCACGTTCCACCAGCTGCGTGCGAAGCAGCGGACGATCCTGCTGCTCGG
CGGCGTGCTCGGCGTGCTGCTGTGCGCGTTGTTCGCGCTGCTGTTCTATACGATGCGCACGCGCGACGCGTTGCTCGAAC
GGCAGAACGCGGCACTCGATGCCGAGCGGCAAGCCTCCGATCGCGCGTTCGAGATGATCGAGGCGAAAAACGCGTTTCTC
GGCATGGTCAGCCACGAACTGCGCACGCCGCTGCAGGCGATTTGCGGGTCGATCGAGATCCTCCTCGCGCGCCCGCAGTC
CGACGCGAACCTGAAGACGATCCGGCGGCTGCAGAATTCGGCGGCGTCGCTCGAAGCGCTCGTCAAGGATCTGACCGACT
ACATCAAGCTGCGCTCGACGAAACGGCTCGCCGATGCGGAAACGGTCGGCATCGCTTCGCTGCTCGCCGACGTGCTCGAT
CCGCTGCGTGCGAAAGTCGACGCGAAAGGGCTCGCGCTTTCATCGCACGTCGCGCCTGCGGATCTCGCCGTGCGCTCCGA
CCGGAAGCTGCTGCGACAGGTGCTCGCGAATCTCGTCGAGAACGCGGTCAAGTACACGCACCGCGGCTCGATCGCCGTGT
CGATCACGCGCGCCGACGCGCCGGCCGGCCCGCAACTGAGGATCGCCGTGCGCGACACCGGCGTCGGCATCGCGAAGGCG
CATCTGTCGAAGATCTTCGAGCCGTTCTATCGCGCGAACGATGCGGTCGGGCTCAGCGTCGACGGCATCGGGATGGGGCT
CGCCGTCGTGCGCGAAATCGTCACGACGCTGCGCGGGCGCGTCGAGGTGCATAGCGTCGCCGGCCAGGGCAGCGAATTCG
TCGTGACGGTGCCGGTCGACGTGCCGGGCGCGGCCGACAGCGCGCACGAAGCGCCGGCCGGTGCGGCGCCCGCCGCGCTG
CGCGACACGCGCGCGCTGATCGTCGACGACAACGACAACGCGCGCGAAACGCTCGGTGCGATGCTCGCGACGCTCGGCAT
CGACGCCGATCTGTGCGGCACCGGCCGCGAAGGCCTCGCGCGCGCGGCCGAGATCGCCTACGACGTCGTGATACTCGATC
TGGAGCTGCCCGACATCAGCGGTGTCGACGTCGCGCGCCGGCTGCGCGCGGCGCGTGCACCCGGCGCGCGCCGCCCGGCG
ATCCTCGGCGTCACGGCGTACGAGTCGCTGGCGCTCGGCGAGAACCGGCAGGCGTTCGACGAATACGTTCCGAAGCCCGT
GCATCTGCGCGAACTCGGCGCGGCGATCGAGCGGCTGCTCGGCTGA

Upstream 100 bases:

>100_bases
CGCTGTGGATCATGTATCCGCGCGACCAGTTTCCGGACGAGCTGAAGACGCCGCTCGGCGAAGCGAAATTCGCATGGCAG
GTCGTCGGGCTGACGGTGAA

Downstream 100 bases:

>100_bases
CGCCGCCGCGCGCGTCCATCGCACGCCGCCCGCCGCCGCCGCGCGCCCGCGTGCGGCTCACTCGCCGATCAGATGCAGCA
CGACGTCGCGCCGATGCGCG

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MTRRRWRNRKVILVLGSVWLLGFAAWAFLLWDLLATSVNEGVLEGPREGVFWTAAQYRNVYTRFNRQLILYATHQDDDFD
KLQMQLDSLSVSFGFLERPSEVSEYWLRIPSARGEIATLGAFMAQLKRDVPKLRDAPQQAPRVLADVDAYWPRVNGLAND
FRAIEMAQRDFTFHQLRAKQRTILLLGGVLGVLLCALFALLFYTMRTRDALLERQNAALDAERQASDRAFEMIEAKNAFL
GMVSHELRTPLQAICGSIEILLARPQSDANLKTIRRLQNSAASLEALVKDLTDYIKLRSTKRLADAETVGIASLLADVLD
PLRAKVDAKGLALSSHVAPADLAVRSDRKLLRQVLANLVENAVKYTHRGSIAVSITRADAPAGPQLRIAVRDTGVGIAKA
HLSKIFEPFYRANDAVGLSVDGIGMGLAVVREIVTTLRGRVEVHSVAGQGSEFVVTVPVDVPGAADSAHEAPAGAAPAAL
RDTRALIVDDNDNARETLGAMLATLGIDADLCGTGREGLARAAEIAYDVVILDLELPDISGVDVARRLRAARAPGARRPA
ILGVTAYESLALGENRQAFDEYVPKPVHLRELGAAIERLLG

Sequences:

>Translated_601_residues
MTRRRWRNRKVILVLGSVWLLGFAAWAFLLWDLLATSVNEGVLEGPREGVFWTAAQYRNVYTRFNRQLILYATHQDDDFD
KLQMQLDSLSVSFGFLERPSEVSEYWLRIPSARGEIATLGAFMAQLKRDVPKLRDAPQQAPRVLADVDAYWPRVNGLAND
FRAIEMAQRDFTFHQLRAKQRTILLLGGVLGVLLCALFALLFYTMRTRDALLERQNAALDAERQASDRAFEMIEAKNAFL
GMVSHELRTPLQAICGSIEILLARPQSDANLKTIRRLQNSAASLEALVKDLTDYIKLRSTKRLADAETVGIASLLADVLD
PLRAKVDAKGLALSSHVAPADLAVRSDRKLLRQVLANLVENAVKYTHRGSIAVSITRADAPAGPQLRIAVRDTGVGIAKA
HLSKIFEPFYRANDAVGLSVDGIGMGLAVVREIVTTLRGRVEVHSVAGQGSEFVVTVPVDVPGAADSAHEAPAGAAPAAL
RDTRALIVDDNDNARETLGAMLATLGIDADLCGTGREGLARAAEIAYDVVILDLELPDISGVDVARRLRAARAPGARRPA
ILGVTAYESLALGENRQAFDEYVPKPVHLRELGAAIERLLG
>Mature_600_residues
TRRRWRNRKVILVLGSVWLLGFAAWAFLLWDLLATSVNEGVLEGPREGVFWTAAQYRNVYTRFNRQLILYATHQDDDFDK
LQMQLDSLSVSFGFLERPSEVSEYWLRIPSARGEIATLGAFMAQLKRDVPKLRDAPQQAPRVLADVDAYWPRVNGLANDF
RAIEMAQRDFTFHQLRAKQRTILLLGGVLGVLLCALFALLFYTMRTRDALLERQNAALDAERQASDRAFEMIEAKNAFLG
MVSHELRTPLQAICGSIEILLARPQSDANLKTIRRLQNSAASLEALVKDLTDYIKLRSTKRLADAETVGIASLLADVLDP
LRAKVDAKGLALSSHVAPADLAVRSDRKLLRQVLANLVENAVKYTHRGSIAVSITRADAPAGPQLRIAVRDTGVGIAKAH
LSKIFEPFYRANDAVGLSVDGIGMGLAVVREIVTTLRGRVEVHSVAGQGSEFVVTVPVDVPGAADSAHEAPAGAAPAALR
DTRALIVDDNDNARETLGAMLATLGIDADLCGTGREGLARAAEIAYDVVILDLELPDISGVDVARRLRAARAPGARRPAI
LGVTAYESLALGENRQAFDEYVPKPVHLRELGAAIERLLG

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=372, Percent_Identity=31.7204301075269, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1788713, Length=339, Percent_Identity=26.8436578171091, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=30.7692307692308, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081816, Length=384, Percent_Identity=28.90625, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1789149, Length=256, Percent_Identity=32.421875, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=29.3333333333333, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1786783, Length=315, Percent_Identity=24.4444444444444, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=27.1929824561404, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1790436, Length=311, Percent_Identity=26.6881028938907, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=29.2576419213974, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082128, Length=240, Percent_Identity=27.5, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1790861, Length=221, Percent_Identity=30.316742081448, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788549, Length=227, Percent_Identity=27.3127753303965, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=271, Percent_Identity=28.4132841328413, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787894, Length=245, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1790551, Length=218, Percent_Identity=27.5229357798165, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=124, Percent_Identity=37.0967741935484, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789808, Length=259, Percent_Identity=23.5521235521236, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65724; Mature: 65593

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRRWRNRKVILVLGSVWLLGFAAWAFLLWDLLATSVNEGVLEGPREGVFWTAAQYRNV
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEHHHHHHH
YTRFNRQLILYATHQDDDFDKLQMQLDSLSVSFGFLERPSEVSEYWLRIPSARGEIATLG
HHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHH
AFMAQLKRDVPKLRDAPQQAPRVLADVDAYWPRVNGLANDFRAIEMAQRDFTFHQLRAKQ
HHHHHHHHHCHHHHCCHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHCCHHHHHHHHH
RTILLLGGVLGVLLCALFALLFYTMRTRDALLERQNAALDAERQASDRAFEMIEAKNAFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GMVSHELRTPLQAICGSIEILLARPQSDANLKTIRRLQNSAASLEALVKDLTDYIKLRST
HHHHHHHHCHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRLADAETVGIASLLADVLDPLRAKVDAKGLALSSHVAPADLAVRSDRKLLRQVLANLVE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
NAVKYTHRGSIAVSITRADAPAGPQLRIAVRDTGVGIAKAHLSKIFEPFYRANDAVGLSV
HHHHHHCCCCEEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEE
DGIGMGLAVVREIVTTLRGRVEVHSVAGQGSEFVVTVPVDVPGAADSAHEAPAGAAPAAL
CCCCHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHH
RDTRALIVDDNDNARETLGAMLATLGIDADLCGTGREGLARAAEIAYDVVILDLELPDIS
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEEEEEECCCCC
GVDVARRLRAARAPGARRPAILGVTAYESLALGENRQAFDEYVPKPVHLRELGAAIERLL
CHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHC
G
C
>Mature Secondary Structure 
TRRRWRNRKVILVLGSVWLLGFAAWAFLLWDLLATSVNEGVLEGPREGVFWTAAQYRNV
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEHHHHHHH
YTRFNRQLILYATHQDDDFDKLQMQLDSLSVSFGFLERPSEVSEYWLRIPSARGEIATLG
HHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHH
AFMAQLKRDVPKLRDAPQQAPRVLADVDAYWPRVNGLANDFRAIEMAQRDFTFHQLRAKQ
HHHHHHHHHCHHHHCCHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHCCHHHHHHHHH
RTILLLGGVLGVLLCALFALLFYTMRTRDALLERQNAALDAERQASDRAFEMIEAKNAFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GMVSHELRTPLQAICGSIEILLARPQSDANLKTIRRLQNSAASLEALVKDLTDYIKLRST
HHHHHHHHCHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRLADAETVGIASLLADVLDPLRAKVDAKGLALSSHVAPADLAVRSDRKLLRQVLANLVE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
NAVKYTHRGSIAVSITRADAPAGPQLRIAVRDTGVGIAKAHLSKIFEPFYRANDAVGLSV
HHHHHHCCCCEEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEE
DGIGMGLAVVREIVTTLRGRVEVHSVAGQGSEFVVTVPVDVPGAADSAHEAPAGAAPAAL
CCCCHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHH
RDTRALIVDDNDNARETLGAMLATLGIDADLCGTGREGLARAAEIAYDVVILDLELPDIS
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEEEEEECCCCC
GVDVARRLRAARAPGARRPAILGVTAYESLALGENRQAFDEYVPKPVHLRELGAAIERLL
CHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]