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The map label for this gene is nahR [H]

Identifier: 189352033

GI number: 189352033

Start: 49163

End: 50059

Strand: Direct

Name: nahR [H]

Synonym: BMULJ_03250

Alternate gene names: 189352033

Gene position: 49163-50059 (Clockwise)

Preceding gene: 189352032

Following gene: 189352048

Centisome position: 1.99

GC content: 66.11

Gene sequence:

>897_bases
ATGCGCCTATCGAAGATTGATCTGAACCTGTTCGTCGTATTCGACGCGATCTACAACAAGCGCAACCTGACGCGTGCGGC
CGAACTGCTGAACCTCACGCAGCCTGCCGTCAGCAATGCGCTCGCGCGGATGCGCAAGACGCTGAACGATCCGCTGTTCG
TCAGCACGCCGGCCGGGATGATGCCGACGCCGTTCGCGGAGAACATCGTCGGGCGCGTGCGCGAGGCGTTGCAGCTGCTC
GATTCGAGCGTGCATGAAGGCGACGTGTTCGATCCGGCGTCGTCGGAGCGCGTGTTCCGGCTGAGCATGAGCGACCTGAC
CGAAGCGCTGCTGCTGCCCGCGCTCGGCGAACTGCTGCAGCGGCAGGCGCCCGGCATGCACGTGCGCAGCTATACGATGG
ATCGCCGCGAAATCGCGACGGCGCTCGCGAACGGCACCGTCGACATCGCGATCGACGCGCCGCTGCTCGGCGATCCGCAT
CTGCATCAGGCGCCGCTCGTGCGCGACCGCTATGCGTGCATGATCCGCGACGGTCATCCGTTCAAGGGCGACACGCTGAC
GATGGACGACTATCTCGCGATGGGGCACATCCACGTGTCGAGCCGCCGCAAGGGCAGCGGGCACGTCGATGCGGAGCTGA
CGCGACTCGGGCTGCGCCGGAACATCCAGATGCGTGTGCAGCACTACATGGTCGCGCCGCTGATCGCGATGCGCGGCGAT
CTCGCGCTGACCGCGCCGCTGCGGCTGCTGCAGCGCTATCCGGCGCGCATTCTCGAACTGCCGTTCGAGATGCCGGGCCT
CGAATACTTCTGCTACTGGCATCGCAGCGCGGATCAGGATCAGGCGAACCGGTGGCTGCGCGAGCGGCTCGCGGAGTTGA
TGCGCGATATGGGGTGA

Upstream 100 bases:

>100_bases
GAGCGTTGCAGGCGGCGCCGCGCACGACGGCGCCGCCGCGGGAGCGAACATGGACGAACGGGCGGCGCGCGCCGTAAGAT
GCCGGCGAGGAGGCTTCGCG

Downstream 100 bases:

>100_bases
CAGGCGCGCTTACAGAACCGACATCGATTCGGTGAGGTTCTGCTTCATGTAGTCGAGGAAGCGCTTCTGGAACAACATCG
TGTGTTCGTGCGCGGCTTTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MRLSKIDLNLFVVFDAIYNKRNLTRAAELLNLTQPAVSNALARMRKTLNDPLFVSTPAGMMPTPFAENIVGRVREALQLL
DSSVHEGDVFDPASSERVFRLSMSDLTEALLLPALGELLQRQAPGMHVRSYTMDRREIATALANGTVDIAIDAPLLGDPH
LHQAPLVRDRYACMIRDGHPFKGDTLTMDDYLAMGHIHVSSRRKGSGHVDAELTRLGLRRNIQMRVQHYMVAPLIAMRGD
LALTAPLRLLQRYPARILELPFEMPGLEYFCYWHRSADQDQANRWLRERLAELMRDMG

Sequences:

>Translated_298_residues
MRLSKIDLNLFVVFDAIYNKRNLTRAAELLNLTQPAVSNALARMRKTLNDPLFVSTPAGMMPTPFAENIVGRVREALQLL
DSSVHEGDVFDPASSERVFRLSMSDLTEALLLPALGELLQRQAPGMHVRSYTMDRREIATALANGTVDIAIDAPLLGDPH
LHQAPLVRDRYACMIRDGHPFKGDTLTMDDYLAMGHIHVSSRRKGSGHVDAELTRLGLRRNIQMRVQHYMVAPLIAMRGD
LALTAPLRLLQRYPARILELPFEMPGLEYFCYWHRSADQDQANRWLRERLAELMRDMG
>Mature_298_residues
MRLSKIDLNLFVVFDAIYNKRNLTRAAELLNLTQPAVSNALARMRKTLNDPLFVSTPAGMMPTPFAENIVGRVREALQLL
DSSVHEGDVFDPASSERVFRLSMSDLTEALLLPALGELLQRQAPGMHVRSYTMDRREIATALANGTVDIAIDAPLLGDPH
LHQAPLVRDRYACMIRDGHPFKGDTLTMDDYLAMGHIHVSSRRKGSGHVDAELTRLGLRRNIQMRVQHYMVAPLIAMRGD
LALTAPLRLLQRYPARILELPFEMPGLEYFCYWHRSADQDQANRWLRERLAELMRDMG

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=299, Percent_Identity=30.1003344481605, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790147, Length=311, Percent_Identity=27.3311897106109, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87081766, Length=191, Percent_Identity=25.6544502617801, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786820, Length=300, Percent_Identity=22.3333333333333, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33754; Mature: 33754

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSKIDLNLFVVFDAIYNKRNLTRAAELLNLTQPAVSNALARMRKTLNDPLFVSTPAGM
CCCEEEECEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
MPTPFAENIVGRVREALQLLDSSVHEGDVFDPASSERVFRLSMSDLTEALLLPALGELLQ
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
RQAPGMHVRSYTMDRREIATALANGTVDIAIDAPLLGDPHLHQAPLVRDRYACMIRDGHP
HCCCCCEEHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHCCEEEEEECCCC
FKGDTLTMDDYLAMGHIHVSSRRKGSGHVDAELTRLGLRRNIQMRVQHYMVAPLIAMRGD
CCCCEEEHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
LALTAPLRLLQRYPARILELPFEMPGLEYFCYWHRSADQDQANRWLRERLAELMRDMG
EEHHHHHHHHHHCCHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLSKIDLNLFVVFDAIYNKRNLTRAAELLNLTQPAVSNALARMRKTLNDPLFVSTPAGM
CCCEEEECEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
MPTPFAENIVGRVREALQLLDSSVHEGDVFDPASSERVFRLSMSDLTEALLLPALGELLQ
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHH
RQAPGMHVRSYTMDRREIATALANGTVDIAIDAPLLGDPHLHQAPLVRDRYACMIRDGHP
HCCCCCEEHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHCCEEEEEECCCC
FKGDTLTMDDYLAMGHIHVSSRRKGSGHVDAELTRLGLRRNIQMRVQHYMVAPLIAMRGD
CCCCEEEHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
LALTAPLRLLQRYPARILELPFEMPGLEYFCYWHRSADQDQANRWLRERLAELMRDMG
EEHHHHHHHHHHCCHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]