| Definition | Orientia tsutsugamushi str. Ikeda, complete genome. |
|---|---|
| Accession | NC_010793 |
| Length | 2,008,987 |
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The map label for this gene is spoT [H]
Identifier: 189184384
GI number: 189184384
Start: 1504318
End: 1504734
Strand: Direct
Name: spoT [H]
Synonym: OTT_1477
Alternate gene names: 189184384
Gene position: 1504318-1504734 (Clockwise)
Preceding gene: 189184383
Following gene: 189184385
Centisome position: 74.88
GC content: 30.7
Gene sequence:
>417_bases TTGGAAGTAGCCTGCACAGTAGCAGAATACAGCTTTGAAACTGATACGATTATTACAGCAATACTACATGATACCATCAA AGATACAACATTAACTAAAGAAAAAATTGCTAAGGTGTTTGGTGTAAAGATTGCAGAACAGGTTTTTGACCTTACCAGAA TTAGGAATAATAAAAAAATCAGTTCTAGAGAAATGATTAAAATATTGCGTCAGCAAAACAAAAAAGATTTGTTATTAATC AAATTATGCGACCGGTTACATAACATTCAAACTGTATTCATAAAATCTGATGAAAAAAGACAAAAAATCATCATTGAAAC TGAGCAAGAATTTATACCTCTTGCTCGACACCTTAAACTATCAAAGATTGCTGACAAGTTAAGTGGATACTGTTTACTTA ATACTTATCTGGAATAA
Upstream 100 bases:
>100_bases ATATATTAATCTTTATGAAGTTACAAAGGCAATAAAATATGCTAAAAAATATCATGGCAAGCAAAAGAGAGATACATGAG AGCAATATTATATACATCCA
Downstream 100 bases:
>100_bases ATGCTAATTCAAAAGCACAACAATATTAGACCTCTTTCGAAACTGGTTAAAGTAGTTCAAAATTATAAATGCTAAAGATC AAATTAAATCTAAGACCTAA
Product: RelA/SpoT-related protein
Products: NA
Alternate protein names: Penta-phosphate guanosine-3'-pyrophosphohydrolase; (ppGpp)ase [H]
Number of amino acids: Translated: 138; Mature: 138
Protein sequence:
>138_residues MEVACTVAEYSFETDTIITAILHDTIKDTTLTKEKIAKVFGVKIAEQVFDLTRIRNNKKISSREMIKILRQQNKKDLLLI KLCDRLHNIQTVFIKSDEKRQKIIIETEQEFIPLARHLKLSKIADKLSGYCLLNTYLE
Sequences:
>Translated_138_residues MEVACTVAEYSFETDTIITAILHDTIKDTTLTKEKIAKVFGVKIAEQVFDLTRIRNNKKISSREMIKILRQQNKKDLLLI KLCDRLHNIQTVFIKSDEKRQKIIIETEQEFIPLARHLKLSKIADKLSGYCLLNTYLE >Mature_138_residues MEVACTVAEYSFETDTIITAILHDTIKDTTLTKEKIAKVFGVKIAEQVFDLTRIRNNKKISSREMIKILRQQNKKDLLLI KLCDRLHNIQTVFIKSDEKRQKIIIETEQEFIPLARHLKLSKIADKLSGYCLLNTYLE
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the degradation of ppGpp into G
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HD domain [H]
Homologues:
Organism=Escherichia coli, GI1790082, Length=133, Percent_Identity=34.5864661654135, Blast_Score=73, Evalue=6e-15,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR012675 - InterPro: IPR003607 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =3.1.7.2 [H]
Molecular weight: Translated: 16066; Mature: 16066
Theoretical pI: Translated: 9.49; Mature: 9.49
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.2 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 2.2 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEVACTVAEYSFETDTIITAILHDTIKDTTLTKEKIAKVFGVKIAEQVFDLTRIRNNKKI CCEEEEEHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC SSREMIKILRQQNKKDLLLIKLCDRLHNIQTVFIKSDEKRQKIIIETEQEFIPLARHLKL CHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHH SKIADKLSGYCLLNTYLE HHHHHHHCCEEEEEECCC >Mature Secondary Structure MEVACTVAEYSFETDTIITAILHDTIKDTTLTKEKIAKVFGVKIAEQVFDLTRIRNNKKI CCEEEEEHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC SSREMIKILRQQNKKDLLLIKLCDRLHNIQTVFIKSDEKRQKIIIETEQEFIPLARHLKL CHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHH SKIADKLSGYCLLNTYLE HHHHHHHCCEEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9537320 [H]