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The map label for this gene is hflK [H]

Identifier: 189184224

GI number: 189184224

Start: 1334825

End: 1335880

Strand: Direct

Name: hflK [H]

Synonym: OTT_1317

Alternate gene names: 189184224

Gene position: 1334825-1335880 (Clockwise)

Preceding gene: 189184222

Following gene: 189184225

Centisome position: 66.44

GC content: 30.59

Gene sequence:

>1056_bases
ATGAAATCACCCTGGGACAATATGGATGATGCAAAAAATATATTTTTAAAAAAAAGTAAAAATAATTTTTTTCTACCTGT
AAATTTTAGTTTTAGCATTAAAACTATGCTAATTTTAATATTTACCATAGTTGTAATTTGGTTATTATCAGGTGTTTATA
AGGTTAATGAAGGGGAGGAAGCTATAGTTATTAGATTTGGTGAATATGTTCGCAAAGCCTATCCTGGATTAAATTATCAT
CTTCCTCATCCTCTAGAAAGGGTAATAATCGAAAGAGTAAAGATGTCAAGACAAACAGAAGTTGGATATAGTTCTGGGCA
ATCTAGAAGAGAGACTAATACTAGTAATGGTAACTATATGGTTTATTCTTATCGACTCAATAATAGAACTATAAATAATC
AACACTTAGGAGAAAGCAGCACTATGTTGACAGGAGATGAGAATATTGTAGAGTTGAATTGTAATGTTAGGTGGCATATT
AAGGATTTGTATTCATTTGTTTTTAATGTTGCTTTTCCGGAGGAGACTGTTAAAATAGTGGCAGAAAGTGCTATTAGAGA
GGTAATTAGTGAAACGCCAATTGCTTCAATTTTATCAAATCAAAAACAGGAAATAGCAGATAAAATTGAAAAATTAATTC
AGCAAATTTTGAATCAATATTCAATTGGTATCGAAATAGAAAAGGTTCAATTATTAAAGGCTGAGCCGCCATCAGAAGTT
ATTGATGCTTATCGTGATGTACAAACTTCAAGAGCTGATAAAGAGCGAGAAATAAATCAAGCTCAAGCTTATAGAAATGA
TAAGATACCTGAAGCTAGAGGAAAGGCAGCTAAGTTGATTGAAGAAGCCAAAGGATATAAGCAAGCAACAGTTTCTAAGG
CGTTAGGAGAGGCTAAGAAATTTAATGCAATATTAGTAGAATATAAGTTAAACAAAGAAATTACTAAAGAACGGTTATAT
CTTAATACTATTGAAACAATATTACAAGGTAGCAAAAAAATTATTATAAGCGATGAGAGTAAATTATTGCCTCATATGGG
TATATCGCTTAAATAA

Upstream 100 bases:

>100_bases
GATTGAAATATTTTTTTTAACTTGCTGTATTAAGTAATATATAAATTTGCAACAGTAACAAGTGTTAAGTAAAACGTTTA
TTAGAATAAAATAGGTTTTT

Downstream 100 bases:

>100_bases
ATATAAGTAGTAAGGTTTAAATCATGACGATAAAAAAAGTGTACTTAACAATTGTTATAGCTGTTGTAGCAGTACTAGCG
ATATTTAATTCTGTGTTTCA

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MKSPWDNMDDAKNIFLKKSKNNFFLPVNFSFSIKTMLILIFTIVVIWLLSGVYKVNEGEEAIVIRFGEYVRKAYPGLNYH
LPHPLERVIIERVKMSRQTEVGYSSGQSRRETNTSNGNYMVYSYRLNNRTINNQHLGESSTMLTGDENIVELNCNVRWHI
KDLYSFVFNVAFPEETVKIVAESAIREVISETPIASILSNQKQEIADKIEKLIQQILNQYSIGIEIEKVQLLKAEPPSEV
IDAYRDVQTSRADKEREINQAQAYRNDKIPEARGKAAKLIEEAKGYKQATVSKALGEAKKFNAILVEYKLNKEITKERLY
LNTIETILQGSKKIIISDESKLLPHMGISLK

Sequences:

>Translated_351_residues
MKSPWDNMDDAKNIFLKKSKNNFFLPVNFSFSIKTMLILIFTIVVIWLLSGVYKVNEGEEAIVIRFGEYVRKAYPGLNYH
LPHPLERVIIERVKMSRQTEVGYSSGQSRRETNTSNGNYMVYSYRLNNRTINNQHLGESSTMLTGDENIVELNCNVRWHI
KDLYSFVFNVAFPEETVKIVAESAIREVISETPIASILSNQKQEIADKIEKLIQQILNQYSIGIEIEKVQLLKAEPPSEV
IDAYRDVQTSRADKEREINQAQAYRNDKIPEARGKAAKLIEEAKGYKQATVSKALGEAKKFNAILVEYKLNKEITKERLY
LNTIETILQGSKKIIISDESKLLPHMGISLK
>Mature_351_residues
MKSPWDNMDDAKNIFLKKSKNNFFLPVNFSFSIKTMLILIFTIVVIWLLSGVYKVNEGEEAIVIRFGEYVRKAYPGLNYH
LPHPLERVIIERVKMSRQTEVGYSSGQSRRETNTSNGNYMVYSYRLNNRTINNQHLGESSTMLTGDENIVELNCNVRWHI
KDLYSFVFNVAFPEETVKIVAESAIREVISETPIASILSNQKQEIADKIEKLIQQILNQYSIGIEIEKVQLLKAEPPSEV
IDAYRDVQTSRADKEREINQAQAYRNDKIPEARGKAAKLIEEAKGYKQATVSKALGEAKKFNAILVEYKLNKEITKERLY
LNTIETILQGSKKIIISDESKLLPHMGISLK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=294, Percent_Identity=29.2517006802721, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 40227; Mature: 40227

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSPWDNMDDAKNIFLKKSKNNFFLPVNFSFSIKTMLILIFTIVVIWLLSGVYKVNEGEE
CCCCCCCCCHHHHEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
AIVIRFGEYVRKAYPGLNYHLPHPLERVIIERVKMSRQTEVGYSSGQSRRETNTSNGNYM
EEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEE
VYSYRLNNRTINNQHLGESSTMLTGDENIVELNCNVRWHIKDLYSFVFNVAFPEETVKIV
EEEEEECCCEECCCCCCCCCCEEECCCCEEEEECCEEEEHHHHHHHHHHHCCCHHHHHHH
AESAIREVISETPIASILSNQKQEIADKIEKLIQQILNQYSIGIEIEKVQLLKAEPPSEV
HHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHH
IDAYRDVQTSRADKEREINQAQAYRNDKIPEARGKAAKLIEEAKGYKQATVSKALGEAKK
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
FNAILVEYKLNKEITKERLYLNTIETILQGSKKIIISDESKLLPHMGISLK
CCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCCC
>Mature Secondary Structure
MKSPWDNMDDAKNIFLKKSKNNFFLPVNFSFSIKTMLILIFTIVVIWLLSGVYKVNEGEE
CCCCCCCCCHHHHEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
AIVIRFGEYVRKAYPGLNYHLPHPLERVIIERVKMSRQTEVGYSSGQSRRETNTSNGNYM
EEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEE
VYSYRLNNRTINNQHLGESSTMLTGDENIVELNCNVRWHIKDLYSFVFNVAFPEETVKIV
EEEEEECCCEECCCCCCCCCCEEECCCCEEEEECCEEEEHHHHHHHHHHHCCCHHHHHHH
AESAIREVISETPIASILSNQKQEIADKIEKLIQQILNQYSIGIEIEKVQLLKAEPPSEV
HHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCHHH
IDAYRDVQTSRADKEREINQAQAYRNDKIPEARGKAAKLIEEAKGYKQATVSKALGEAKK
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
FNAILVEYKLNKEITKERLYLNTIETILQGSKKIIISDESKLLPHMGISLK
CCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]