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The map label for this gene is intD [H]

Identifier: 189184134

GI number: 189184134

Start: 1260428

End: 1261567

Strand: Reverse

Name: intD [H]

Synonym: OTT_1227

Alternate gene names: 189184134

Gene position: 1261567-1260428 (Counterclockwise)

Preceding gene: 189184136

Following gene: 189184133

Centisome position: 62.8

GC content: 28.33

Gene sequence:

>1140_bases
ATGGTAGTGATATTATATTTTACACAAATAGCTATAAGTAAAATAAAGCCCCCAAAAGAAAAAAGAGATGTATACAGAGA
TACTAAAGACAAAGGTTTATTTCTAGAAGTATTGTATGGAGGAACTAAAACACTTTATTTAGGGATAACAATTAAAGGAG
TATATAGAAAAATTAAGTTAGGGAATTTTCCAAATATATCTGTTAATTATGCTAGAAAAAAAACGCTGATTTTAAAGGGA
CAAATTGCTAAAGGAATAGATCCTTTAAAAACAAAGAATGCATCAACATTGAAGGAGGTATATGATCTATATATTAATCA
TCGAAAACTCAAAGATAGTAGCAAAATTTTATACAAAGGCATTATGAATAAGTATTTAAAAAACTTGCACTATATTCATG
TTTCTAATATTCGAAAAGAAGATATTTATAAGATATTTAATAATGCAAAAAAAGGTGGTAAATATTCAGCAAACAAAACG
CTTAAGTTAATAAAAGCAATATTGAACATAGCAGTAGAATTAGAATTAATAGAAAAAAATCCAGCTAATGGAATAAAAAT
TCATAAAATGCAAGCAAGAGATAGATATATAACTCTAGAAGAGATGCCAAGATTCTTAGCAGCAGTTGAAGAAGATAAGA
ATCCATACTTAAAATATTTTGTCTATATAAGTTTATATACTGCAGCTCGTAGAAATAATGTATTATCAATGCGTTGGGAA
AATATAAGACTGGAAGAAGGAGTGTGGTATATACCAGAGACTAAGAATGGAGAATCGCAAACAGTGCCATTAATAAATTT
ACTAATAGAAAAATTAAAACAGTATTCATATTCATCAGAAAGTGAGTGGGTATTTCCTGGACAAAGAAGAAATAGCGGAC
ATTTAACGAGCATAAATGTAGCATGGAAAAGAGTTTGTAAAAGAGCTGGATTAAAAAATTTAAGGATACACGATCTTAGA
AGAACTGTTGGTAGTTGGATGGCAAAATTTGGAATGCCAATAGCTGTAATTAGCAAATTGTTAAATCATAATGACCATCA
ATCAACAAAATTTTATATACATCTTAATACAAATGTTGTACGAGATGCAATACAAAAATTTGCTAACGAAATTGCTAAGT
GCACTAATTTACGAGACTAA

Upstream 100 bases:

>100_bases
TTACTGAATTTTTACGAAAAAACTTGCTTTTTCAAAAAAAGCATACAACAGATTGTTTTTCTAATCTTAAATATTAATAG
TTGAATAAAGGTGATTTATT

Downstream 100 bases:

>100_bases
ACATGAAAAATTTAACAATTAATGATGATGCGCCAGACTTTAATATGATTACTACTAGTAATTCAATTATAAATCTAGGT
CATTATGAAGGTAAAAATTT

Product: putative integrase

Products: NA

Alternate protein names: Prophage QSR' integrase [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MVVILYFTQIAISKIKPPKEKRDVYRDTKDKGLFLEVLYGGTKTLYLGITIKGVYRKIKLGNFPNISVNYARKKTLILKG
QIAKGIDPLKTKNASTLKEVYDLYINHRKLKDSSKILYKGIMNKYLKNLHYIHVSNIRKEDIYKIFNNAKKGGKYSANKT
LKLIKAILNIAVELELIEKNPANGIKIHKMQARDRYITLEEMPRFLAAVEEDKNPYLKYFVYISLYTAARRNNVLSMRWE
NIRLEEGVWYIPETKNGESQTVPLINLLIEKLKQYSYSSESEWVFPGQRRNSGHLTSINVAWKRVCKRAGLKNLRIHDLR
RTVGSWMAKFGMPIAVISKLLNHNDHQSTKFYIHLNTNVVRDAIQKFANEIAKCTNLRD

Sequences:

>Translated_379_residues
MVVILYFTQIAISKIKPPKEKRDVYRDTKDKGLFLEVLYGGTKTLYLGITIKGVYRKIKLGNFPNISVNYARKKTLILKG
QIAKGIDPLKTKNASTLKEVYDLYINHRKLKDSSKILYKGIMNKYLKNLHYIHVSNIRKEDIYKIFNNAKKGGKYSANKT
LKLIKAILNIAVELELIEKNPANGIKIHKMQARDRYITLEEMPRFLAAVEEDKNPYLKYFVYISLYTAARRNNVLSMRWE
NIRLEEGVWYIPETKNGESQTVPLINLLIEKLKQYSYSSESEWVFPGQRRNSGHLTSINVAWKRVCKRAGLKNLRIHDLR
RTVGSWMAKFGMPIAVISKLLNHNDHQSTKFYIHLNTNVVRDAIQKFANEIAKCTNLRD
>Mature_379_residues
MVVILYFTQIAISKIKPPKEKRDVYRDTKDKGLFLEVLYGGTKTLYLGITIKGVYRKIKLGNFPNISVNYARKKTLILKG
QIAKGIDPLKTKNASTLKEVYDLYINHRKLKDSSKILYKGIMNKYLKNLHYIHVSNIRKEDIYKIFNNAKKGGKYSANKT
LKLIKAILNIAVELELIEKNPANGIKIHKMQARDRYITLEEMPRFLAAVEEDKNPYLKYFVYISLYTAARRNNVLSMRWE
NIRLEEGVWYIPETKNGESQTVPLINLLIEKLKQYSYSSESEWVFPGQRRNSGHLTSINVAWKRVCKRAGLKNLRIHDLR
RTVGSWMAKFGMPIAVISKLLNHNDHQSTKFYIHLNTNVVRDAIQKFANEIAKCTNLRD

Specific function: Integrase from the cryptic lambdoic prophage DLP12. Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1786748, Length=331, Percent_Identity=25.3776435045317, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693166, Length=291, Percent_Identity=23.0240549828179, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788690, Length=358, Percent_Identity=23.7430167597765, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44044; Mature: 44044

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVILYFTQIAISKIKPPKEKRDVYRDTKDKGLFLEVLYGGTKTLYLGITIKGVYRKIKL
CEEEEEEHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEEECCCEEEEEEEEEEEHHHEEEC
GNFPNISVNYARKKTLILKGQIAKGIDPLKTKNASTLKEVYDLYINHRKLKDSSKILYKG
CCCCCCEEEECCCEEEEEECCHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
IMNKYLKNLHYIHVSNIRKEDIYKIFNNAKKGGKYSANKTLKLIKAILNIAVELELIEKN
HHHHHHHHCEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEECC
PANGIKIHKMQARDRYITLEEMPRFLAAVEEDKNPYLKYFVYISLYTAARRNNVLSMRWE
CCCCEEEEEEECCCCEEEHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHCCCEEEEEEC
NIRLEEGVWYIPETKNGESQTVPLINLLIEKLKQYSYSSESEWVFPGQRRNSGHLTSINV
CEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCEEEEHH
AWKRVCKRAGLKNLRIHDLRRTVGSWMAKFGMPIAVISKLLNHNDHQSTKFYIHLNTNVV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCHHH
RDAIQKFANEIAKCTNLRD
HHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVVILYFTQIAISKIKPPKEKRDVYRDTKDKGLFLEVLYGGTKTLYLGITIKGVYRKIKL
CEEEEEEHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEEECCCEEEEEEEEEEEHHHEEEC
GNFPNISVNYARKKTLILKGQIAKGIDPLKTKNASTLKEVYDLYINHRKLKDSSKILYKG
CCCCCCEEEECCCEEEEEECCHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
IMNKYLKNLHYIHVSNIRKEDIYKIFNNAKKGGKYSANKTLKLIKAILNIAVELELIEKN
HHHHHHHHCEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEECC
PANGIKIHKMQARDRYITLEEMPRFLAAVEEDKNPYLKYFVYISLYTAARRNNVLSMRWE
CCCCEEEEEEECCCCEEEHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHCCCEEEEEEC
NIRLEEGVWYIPETKNGESQTVPLINLLIEKLKQYSYSSESEWVFPGQRRNSGHLTSINV
CEEEECCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCEEEEHH
AWKRVCKRAGLKNLRIHDLRRTVGSWMAKFGMPIAVISKLLNHNDHQSTKFYIHLNTNVV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEEEEECCHHH
RDAIQKFANEIAKCTNLRD
HHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2553674; 2183007; 9278503 [H]