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The map label for this gene is dnaB [H]

Identifier: 189184127

GI number: 189184127

Start: 1252352

End: 1252975

Strand: Direct

Name: dnaB [H]

Synonym: OTT_1220

Alternate gene names: 189184127

Gene position: 1252352-1252975 (Clockwise)

Preceding gene: 189184126

Following gene: 189184128

Centisome position: 62.34

GC content: 31.25

Gene sequence:

>624_bases
ATGGGTAAAACTGCTTTAGGAGTTAACTTAGCAATAAATGCTTGTAAATATTTTCTTACTCAAAAAAATACTAAAGATAA
TGTAGTGCAATCAGTTGGCTTATTTTCTTTAGAAATGTCATCTCAGCAAATCTCAACTCGAATTCTTTCTATAGAATCAG
AAATTAATAGCTCTGCATTATTTAATGGAAAAATAGGTGAACAAGATGTTGATAAGTTGAAGACTGTACAAGATGAAATA
CAAAAGTGGAATTTTTTTATAGATGACGCTCCGGCAATCTCAATATCTGCAATTAGATCTCGAGCTCGTAGACTTAAACG
TACTCATAATTTAGCAATATTATTTATTGATTATTTACAGCTAATAAAAATTGATTCCAGAGGAAGTCAGTATAATCGAG
TACAGGAGATTTCTGAAATTACTCAGAGCTTAAAAGCTCTTGCAAAAGAACTTAATATTCCAGTAGTAGAACAAAGGTCA
GATAAAAAGCATATTCTCTCAGATATGAGAGAATCAGGCTCCATTGAACAAGATGCCGATATTGTAATGCTTATATATCG
GATAGTAGGTATTCTAAATTTGGCAATATTGTTAAAAACTCTCAGCAAGGTTAATAAACGCTAG

Upstream 100 bases:

>100_bases
AAACTCTATTAATGGCATTAGTAGTGGACTACTTGATCTTGATTCAAAGCTTGGAGGGTTTAAAAATTCTGACTTAATAA
TATTAGCTGGCAGGCCTTCA

Downstream 100 bases:

>100_bases
ATTATGCATAAGATGAAAAAATGCTGGTCAAAAAAAATTACAGCAAAATTTTACTCATTAACACCAGAGATATGCAACTC
AAGATTGGTTTTTTTAACAT

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MGKTALGVNLAINACKYFLTQKNTKDNVVQSVGLFSLEMSSQQISTRILSIESEINSSALFNGKIGEQDVDKLKTVQDEI
QKWNFFIDDAPAISISAIRSRARRLKRTHNLAILFIDYLQLIKIDSRGSQYNRVQEISEITQSLKALAKELNIPVVEQRS
DKKHILSDMRESGSIEQDADIVMLIYRIVGILNLAILLKTLSKVNKR

Sequences:

>Translated_207_residues
MGKTALGVNLAINACKYFLTQKNTKDNVVQSVGLFSLEMSSQQISTRILSIESEINSSALFNGKIGEQDVDKLKTVQDEI
QKWNFFIDDAPAISISAIRSRARRLKRTHNLAILFIDYLQLIKIDSRGSQYNRVQEISEITQSLKALAKELNIPVVEQRS
DKKHILSDMRESGSIEQDADIVMLIYRIVGILNLAILLKTLSKVNKR
>Mature_206_residues
GKTALGVNLAINACKYFLTQKNTKDNVVQSVGLFSLEMSSQQISTRILSIESEINSSALFNGKIGEQDVDKLKTVQDEIQ
KWNFFIDDAPAISISAIRSRARRLKRTHNLAILFIDYLQLIKIDSRGSQYNRVQEISEITQSLKALAKELNIPVVEQRSD
KKHILSDMRESGSIEQDADIVMLIYRIVGILNLAILLKTLSKVNKR

Specific function: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins [

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=198, Percent_Identity=42.9292929292929, Blast_Score=143, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 23365; Mature: 23234

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKTALGVNLAINACKYFLTQKNTKDNVVQSVGLFSLEMSSQQISTRILSIESEINSSAL
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
FNGKIGEQDVDKLKTVQDEIQKWNFFIDDAPAISISAIRSRARRLKRTHNLAILFIDYLQ
ECCCCCHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LIKIDSRGSQYNRVQEISEITQSLKALAKELNIPVVEQRSDKKHILSDMRESGSIEQDAD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHH
IVMLIYRIVGILNLAILLKTLSKVNKR
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GKTALGVNLAINACKYFLTQKNTKDNVVQSVGLFSLEMSSQQISTRILSIESEINSSAL
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
FNGKIGEQDVDKLKTVQDEIQKWNFFIDDAPAISISAIRSRARRLKRTHNLAILFIDYLQ
ECCCCCHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LIKIDSRGSQYNRVQEISEITQSLKALAKELNIPVVEQRSDKKHILSDMRESGSIEQDAD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCHH
IVMLIYRIVGILNLAILLKTLSKVNKR
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA