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The map label for this gene is aprE [H]

Identifier: 189184014

GI number: 189184014

Start: 1136871

End: 1138409

Strand: Reverse

Name: aprE [H]

Synonym: OTT_1107

Alternate gene names: 189184014

Gene position: 1138409-1136871 (Counterclockwise)

Preceding gene: 189184015

Following gene: 189184010

Centisome position: 56.67

GC content: 32.23

Gene sequence:

>1539_bases
ATGTCTCAGCTTTGGAATGATAATAATAATGGCATAAAGGGAGTAATACCTAAAATGTCGCCTCAGGATCGAAAAAATAT
AATGGATGTGTTATTGCAAAATCAGCAAAAACAACAAAAACTAGAAAAGAGTAAATGGCTAAAATCATTGCTTAAAGCAA
TATTGTTACAGTTAACACGATTGATTTATGGTATAGGTAATGCTGTAGATAGCTTTATTAGTTTTATTATTAACTCAAAA
GGTACAGCAAAAAATATTGTAGTTCAGACTGCAAGAGGGCCAATATTGTTTGGAGTTTGGGTCATGATTATTTTTATTGT
AGTAGGTGGTTTATGGAGTGCATTAGCTCCACTTGACAGTGCTGCAGTAGCTGTTGGAACTGTGATATCAAGTACTGAAA
ATAAAATTATACAGCATCAGGAAGGTGGTATTGTTAAAGAAATTTTTGTTAAACAAGGTGATTACGTTAAGACAGGTGAT
CCTATAATAGCATTGGACGATACTAAAATTAGAGCTAGTGTAGAAATTAAGCTAGGTCAATATAGAACATTATTAGCTAA
TCAGGCTAGGTTAACTGCTGAACTAGAGCAACAAGAAGAAATAATATTTTCTGAATTTTTGGTTAATAATAACCATATAC
CAGAAGTAGCAAAAATAATGTCAATTCAGCAGCATCTATTTCAAGCAAGAAAGAAAGGCTTAAATGCAAGAATCATGCAA
TTTGAAAAAAGAATTGATTCTTTAGAGGCTAAAGTAGTAGCATCCAAAAAGCAGCTTGAGTATGTTAGAAAGCTTATTAA
GAACGCTGAAAGCCTAATTGCTCAAGGTTTTGGACAAAAAACAGAGCTGGATAAATTGTTGGTTGAAGAATCAAGCTTGG
TAGGTAATATCATAATTACTGAACTTGAGATAAACAGTACTCAGCAAGATATCGAACGAACAAAGTCTGAAGCAATAGAT
CGTACATTATCTGAACTTAAAGAAGTTGAACATGCTGTCATTGAAGCTCAAGAAAGCTATAACTCTTTGATTGATATATT
AAGCAGAACCTTAGTAAAATCTCCAGTTGATGGTATAATTAAGGTTTTGGATGTTAATACTCAAGGTGGAGTTATTGGAT
CTGGACAAAGGATTGCAGAAATTACACCTAGTAATGATTCTCTGATAATTAAAGCTAAAATTCCTCAAAAGAATATTGAT
TCAGTCAAGGTAGGATTGAAGGCTAAAATAAGATTTGGTGCTTTCAAATATAGAACTACACCAGTGTTTACTGGGAGGGT
AGTGCTAGTATCGCCTGATACAGTTCAAGATCAACAATCAGCAATGCAGTTTAATAATGCAATGATAGGTGATACCTTTT
ATATTGCTAAAATAGAAATAGATATGGATGAATTTAATAAAGTAGCAAAAGTTAAAAATTTAAAACTATTTCCAGGAATG
CAAGCTGATATTCAAATTATTACTGGCACTAGAACTTTATTAAGATACTTGCTTGATCCAATAACTGATAACATGTTTAG
AGCATTTACTGAGAAATAA

Upstream 100 bases:

>100_bases
TTTGGAGATAGAGAAGAAGTTATGAATCAGCTTAATAATCATAAAAGAAGTATTCATAAATAGGATAGTAATATAATTAA
TTAAAGATTTGGGTAAAAAA

Downstream 100 bases:

>100_bases
AAAATGCCTTTGTATGCCTTTTATTAAGAAGTAAAGGTTTTATAGGATGAATTACTTTTTCTTTCATGTTAGAGCTGATT
TTTAAAATTAGCTCTAACCC

Product: alkaline protease secretion protein AprE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MSQLWNDNNNGIKGVIPKMSPQDRKNIMDVLLQNQQKQQKLEKSKWLKSLLKAILLQLTRLIYGIGNAVDSFISFIINSK
GTAKNIVVQTARGPILFGVWVMIIFIVVGGLWSALAPLDSAAVAVGTVISSTENKIIQHQEGGIVKEIFVKQGDYVKTGD
PIIALDDTKIRASVEIKLGQYRTLLANQARLTAELEQQEEIIFSEFLVNNNHIPEVAKIMSIQQHLFQARKKGLNARIMQ
FEKRIDSLEAKVVASKKQLEYVRKLIKNAESLIAQGFGQKTELDKLLVEESSLVGNIIITELEINSTQQDIERTKSEAID
RTLSELKEVEHAVIEAQESYNSLIDILSRTLVKSPVDGIIKVLDVNTQGGVIGSGQRIAEITPSNDSLIIKAKIPQKNID
SVKVGLKAKIRFGAFKYRTTPVFTGRVVLVSPDTVQDQQSAMQFNNAMIGDTFYIAKIEIDMDEFNKVAKVKNLKLFPGM
QADIQIITGTRTLLRYLLDPITDNMFRAFTEK

Sequences:

>Translated_512_residues
MSQLWNDNNNGIKGVIPKMSPQDRKNIMDVLLQNQQKQQKLEKSKWLKSLLKAILLQLTRLIYGIGNAVDSFISFIINSK
GTAKNIVVQTARGPILFGVWVMIIFIVVGGLWSALAPLDSAAVAVGTVISSTENKIIQHQEGGIVKEIFVKQGDYVKTGD
PIIALDDTKIRASVEIKLGQYRTLLANQARLTAELEQQEEIIFSEFLVNNNHIPEVAKIMSIQQHLFQARKKGLNARIMQ
FEKRIDSLEAKVVASKKQLEYVRKLIKNAESLIAQGFGQKTELDKLLVEESSLVGNIIITELEINSTQQDIERTKSEAID
RTLSELKEVEHAVIEAQESYNSLIDILSRTLVKSPVDGIIKVLDVNTQGGVIGSGQRIAEITPSNDSLIIKAKIPQKNID
SVKVGLKAKIRFGAFKYRTTPVFTGRVVLVSPDTVQDQQSAMQFNNAMIGDTFYIAKIEIDMDEFNKVAKVKNLKLFPGM
QADIQIITGTRTLLRYLLDPITDNMFRAFTEK
>Mature_511_residues
SQLWNDNNNGIKGVIPKMSPQDRKNIMDVLLQNQQKQQKLEKSKWLKSLLKAILLQLTRLIYGIGNAVDSFISFIINSKG
TAKNIVVQTARGPILFGVWVMIIFIVVGGLWSALAPLDSAAVAVGTVISSTENKIIQHQEGGIVKEIFVKQGDYVKTGDP
IIALDDTKIRASVEIKLGQYRTLLANQARLTAELEQQEEIIFSEFLVNNNHIPEVAKIMSIQQHLFQARKKGLNARIMQF
EKRIDSLEAKVVASKKQLEYVRKLIKNAESLIAQGFGQKTELDKLLVEESSLVGNIIITELEINSTQQDIERTKSEAIDR
TLSELKEVEHAVIEAQESYNSLIDILSRTLVKSPVDGIIKVLDVNTQGGVIGSGQRIAEITPSNDSLIIKAKIPQKNIDS
VKVGLKAKIRFGAFKYRTTPVFTGRVVLVSPDTVQDQQSAMQFNNAMIGDTFYIAKIEIDMDEFNKVAKVKNLKLFPGMQ
ADIQIITGTRTLLRYLLDPITDNMFRAFTEK

Specific function: Involved in the secretion of alkaline protease [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 57190; Mature: 57059

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLWNDNNNGIKGVIPKMSPQDRKNIMDVLLQNQQKQQKLEKSKWLKSLLKAILLQLTR
CCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIYGIGNAVDSFISFIINSKGTAKNIVVQTARGPILFGVWVMIIFIVVGGLWSALAPLDS
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
AAVAVGTVISSTENKIIQHQEGGIVKEIFVKQGDYVKTGDPIIALDDTKIRASVEIKLGQ
HHHHHHHHHHCCHHHHHHHCCCCHHHHHHHCCCCEEECCCCEEEECCCEEEEEEEEEECH
YRTLLANQARLTAELEQQEEIIFSEFLVNNNHIPEVAKIMSIQQHLFQARKKGLNARIMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
FEKRIDSLEAKVVASKKQLEYVRKLIKNAESLIAQGFGQKTELDKLLVEESSLVGNIIIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEE
ELEINSTQQDIERTKSEAIDRTLSELKEVEHAVIEAQESYNSLIDILSRTLVKSPVDGII
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHE
KVLDVNTQGGVIGSGQRIAEITPSNDSLIIKAKIPQKNIDSVKVGLKAKIRFGAFKYRTT
EEEEECCCCCEEECCCEEEEECCCCCCEEEEEECCCCCCCCEEECEEEEEEECEEEEECC
PVFTGRVVLVSPDTVQDQQSAMQFNNAMIGDTFYIAKIEIDMDEFNKVAKVKNLKLFPGM
CEEECEEEEECCCCCHHHHHHHHHCCCEECCEEEEEEEEECHHHHHHHHHHCCCEECCCC
QADIQIITGTRTLLRYLLDPITDNMFRAFTEK
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQLWNDNNNGIKGVIPKMSPQDRKNIMDVLLQNQQKQQKLEKSKWLKSLLKAILLQLTR
CCCCCCCCCCCEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LIYGIGNAVDSFISFIINSKGTAKNIVVQTARGPILFGVWVMIIFIVVGGLWSALAPLDS
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
AAVAVGTVISSTENKIIQHQEGGIVKEIFVKQGDYVKTGDPIIALDDTKIRASVEIKLGQ
HHHHHHHHHHCCHHHHHHHCCCCHHHHHHHCCCCEEECCCCEEEECCCEEEEEEEEEECH
YRTLLANQARLTAELEQQEEIIFSEFLVNNNHIPEVAKIMSIQQHLFQARKKGLNARIMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
FEKRIDSLEAKVVASKKQLEYVRKLIKNAESLIAQGFGQKTELDKLLVEESSLVGNIIIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEE
ELEINSTQQDIERTKSEAIDRTLSELKEVEHAVIEAQESYNSLIDILSRTLVKSPVDGII
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHE
KVLDVNTQGGVIGSGQRIAEITPSNDSLIIKAKIPQKNIDSVKVGLKAKIRFGAFKYRTT
EEEEECCCCCEEECCCEEEEECCCCCCEEEEEECCCCCCCCEEECEEEEEEECEEEEECC
PVFTGRVVLVSPDTVQDQQSAMQFNNAMIGDTFYIAKIEIDMDEFNKVAKVKNLKLFPGM
CEEECEEEEECCCCCHHHHHHHHHCCCEECCEEEEEEEEECHHHHHHHHHHCCCEECCCC
QADIQIITGTRTLLRYLLDPITDNMFRAFTEK
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]