| Definition | Orientia tsutsugamushi str. Ikeda, complete genome. |
|---|---|
| Accession | NC_010793 |
| Length | 2,008,987 |
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The map label for this gene is fabG [H]
Identifier: 189183946
GI number: 189183946
Start: 1079592
End: 1080317
Strand: Reverse
Name: fabG [H]
Synonym: OTT_1039
Alternate gene names: 189183946
Gene position: 1080317-1079592 (Counterclockwise)
Preceding gene: 189183947
Following gene: 189183945
Centisome position: 53.77
GC content: 32.37
Gene sequence:
>726_bases GTGTTAAATTTTACTAACCAACACGTACTTATTACAGGAGCATCAGGCAGCATAGGAAGAGCGTGCAGTCAGTTATTTCA TCAACTAGGAGCTACAGTAATAATTTCCGGGACTAAAGAAGAAAAACTTGCTAAATTAAAAGCAGATTTAACAGAAAGAT GCATTGTTCGCAAATGTAATATCTTAGACTATCAAGATTGCAATAATATGATTGAAGAAATACCAAAACTTGATGTATTA ATATGTTGCGCTGGCATTACTAATGATCAATTAGCAATTAAAATGGAAGTTGCAAAATTTGAAACAGTGATCTCTACAAA TCTAACAGCCACATTCATTTTAAATAAAGCAGCAATAAAAAAAATGATTAAAGAGCGATATGGTAGAATAATAAATATAT CTTCAGTTGTAGCTATTAGTGGAAACCAAGGCCAATCAAATTATTGTGCATCTAAAGCTGGCATTATTGGAATGAGTAAA GCATTAGCATTAGAAGTAGCAAGTCGAAATATAACTGTTAATGTTATTGCACCAGGATTTATTATATCCAATATGACAAA TCTGCTTAATGAACAACAAAAAAATACTATACTATCTAAAATTCCAGTAAATAGATTTGGAAATCCAAACGATATTGCAA CCGCGGCAGCATTCTTAGCTAGTAGGCAAGCAGCATATATTTCTGGACAAACTTTACATGTAAATGGCGGCATGGTTATG GTATGA
Upstream 100 bases:
>100_bases AAAAATCTGATATTATACAAAATAGCCTAGTTATCCCTAATGAGAATGAACATGAAGCTAATCTAGATAATATATCTATA GCAACAGAAGAAAAGAACAA
Downstream 100 bases:
>100_bases AATTAAGAATTTTAGTAGCATTAATTCATAAAGTATGGTAAAAGAATATTAATTTTACTAAAGTAAAATACTTTTAGTAA TGCATAATTGTTTCTTTAAT
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 241; Mature: 241
Protein sequence:
>241_residues MLNFTNQHVLITGASGSIGRACSQLFHQLGATVIISGTKEEKLAKLKADLTERCIVRKCNILDYQDCNNMIEEIPKLDVL ICCAGITNDQLAIKMEVAKFETVISTNLTATFILNKAAIKKMIKERYGRIINISSVVAISGNQGQSNYCASKAGIIGMSK ALALEVASRNITVNVIAPGFIISNMTNLLNEQQKNTILSKIPVNRFGNPNDIATAAAFLASRQAAYISGQTLHVNGGMVM V
Sequences:
>Translated_241_residues MLNFTNQHVLITGASGSIGRACSQLFHQLGATVIISGTKEEKLAKLKADLTERCIVRKCNILDYQDCNNMIEEIPKLDVL ICCAGITNDQLAIKMEVAKFETVISTNLTATFILNKAAIKKMIKERYGRIINISSVVAISGNQGQSNYCASKAGIIGMSK ALALEVASRNITVNVIAPGFIISNMTNLLNEQQKNTILSKIPVNRFGNPNDIATAAAFLASRQAAYISGQTLHVNGGMVM V >Mature_241_residues MLNFTNQHVLITGASGSIGRACSQLFHQLGATVIISGTKEEKLAKLKADLTERCIVRKCNILDYQDCNNMIEEIPKLDVL ICCAGITNDQLAIKMEVAKFETVISTNLTATFILNKAAIKKMIKERYGRIINISSVVAISGNQGQSNYCASKAGIIGMSK ALALEVASRNITVNVIAPGFIISNMTNLLNEQQKNTILSKIPVNRFGNPNDIATAAAFLASRQAAYISGQTLHVNGGMVM V
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=235, Percent_Identity=35.3191489361702, Blast_Score=149, Evalue=2e-36, Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=35.9683794466403, Blast_Score=145, Evalue=3e-35, Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=29.3877551020408, Blast_Score=114, Evalue=7e-26, Organism=Homo sapiens, GI19923817, Length=247, Percent_Identity=31.5789473684211, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI126723750, Length=247, Percent_Identity=28.3400809716599, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=25.4032258064516, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=32.1052631578947, Blast_Score=91, Evalue=6e-19, Organism=Homo sapiens, GI66933014, Length=222, Percent_Identity=25.6756756756757, Blast_Score=88, Evalue=6e-18, Organism=Homo sapiens, GI10190704, Length=242, Percent_Identity=26.0330578512397, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=26.7206477732794, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI4503817, Length=207, Percent_Identity=29.951690821256, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI59889578, Length=223, Percent_Identity=29.5964125560538, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI4758504, Length=248, Percent_Identity=25.4032258064516, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=25.5102040816327, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=28.3505154639175, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI31542939, Length=186, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI33667109, Length=199, Percent_Identity=26.1306532663317, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=27.4725274725275, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI157739938, Length=191, Percent_Identity=25.6544502617801, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=46.3114754098361, Blast_Score=217, Evalue=6e-58, Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=28.1124497991968, Blast_Score=118, Evalue=3e-28, Organism=Escherichia coli, GI1789208, Length=175, Percent_Identity=34.2857142857143, Blast_Score=115, Evalue=2e-27, Organism=Escherichia coli, GI87082160, Length=259, Percent_Identity=29.3436293436293, Blast_Score=111, Evalue=5e-26, Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=29.2181069958848, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=28.968253968254, Blast_Score=105, Evalue=2e-24, Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=30.9917355371901, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=28.8617886178862, Blast_Score=95, Evalue=4e-21, Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=29.6296296296296, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=28.2868525896414, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=25, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1787526, Length=182, Percent_Identity=31.8681318681319, Blast_Score=81, Evalue=5e-17, Organism=Escherichia coli, GI1789057, Length=184, Percent_Identity=28.804347826087, Blast_Score=80, Evalue=9e-17, Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=28.0898876404494, Blast_Score=79, Evalue=3e-16, Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=34.5833333333333, Blast_Score=137, Evalue=5e-33, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=31.8367346938775, Blast_Score=130, Evalue=6e-31, Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=31.4741035856574, Blast_Score=120, Evalue=7e-28, Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=28.7313432835821, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=30.2238805970149, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=28.3582089552239, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=27.3764258555133, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=28.4552845528455, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=29.3233082706767, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI72000259, Length=272, Percent_Identity=30.5147058823529, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17538182, Length=248, Percent_Identity=26.6129032258064, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=27.0676691729323, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=27.7153558052434, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=26.4, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=27.3408239700375, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17538486, Length=272, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560220, Length=273, Percent_Identity=26.7399267399267, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=28.030303030303, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=26.1363636363636, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=27.9245283018868, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=26.3940520446097, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=25.3061224489796, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=25, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17568967, Length=190, Percent_Identity=25.7894736842105, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=28.1481481481481, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=27.7153558052434, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=26.5060240963855, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=25.6505576208178, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=26.9035532994924, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=29.8429319371728, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI193203115, Length=191, Percent_Identity=27.2251308900524, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17508651, Length=177, Percent_Identity=28.8135593220339, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17561272, Length=233, Percent_Identity=24.8927038626609, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17536025, Length=243, Percent_Identity=24.6913580246914, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=34.7150259067358, Blast_Score=100, Evalue=2e-22, Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=27.4193548387097, Blast_Score=94, Evalue=3e-20, Organism=Saccharomyces cerevisiae, GI6323882, Length=242, Percent_Identity=25.2066115702479, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI24639444, Length=237, Percent_Identity=33.3333333333333, Blast_Score=131, Evalue=5e-31, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=30.1204819277108, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=30.8, Blast_Score=103, Evalue=8e-23, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=27.710843373494, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI24643142, Length=231, Percent_Identity=26.8398268398268, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=28.2945736434109, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=32.1052631578947, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=25.4901960784314, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=28.6852589641434, Blast_Score=88, Evalue=7e-18, Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=29.3436293436293, Blast_Score=84, Evalue=7e-17, Organism=Drosophila melanogaster, GI21358495, Length=204, Percent_Identity=27.9411764705882, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI24584748, Length=238, Percent_Identity=23.109243697479, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI161076933, Length=238, Percent_Identity=23.109243697479, Blast_Score=71, Evalue=7e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25992; Mature: 25992
Theoretical pI: Translated: 9.32; Mature: 9.32
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.9 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 6.2 %Cys+Met (Translated Protein) 2.9 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 6.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLNFTNQHVLITGASGSIGRACSQLFHQLGATVIISGTKEEKLAKLKADLTERCIVRKCN CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCC ILDYQDCNNMIEEIPKLDVLICCAGITNDQLAIKMEVAKFETVISTNLTATFILNKAAIK CCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEHHHHHHHHHCCCEEEEEECHHHHH KMIKERYGRIINISSVVAISGNQGQSNYCASKAGIIGMSKALALEVASRNITVNVIAPGF HHHHHHCCCEEEEEEEEEEECCCCCCCHHHHHCCCEEHHHHHEEEEECCCEEEEEEECCH IISNMTNLLNEQQKNTILSKIPVNRFGNPNDIATAAAFLASRQAAYISGQTLHVNGGMVM HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEECCCEEEECCCEEE V C >Mature Secondary Structure MLNFTNQHVLITGASGSIGRACSQLFHQLGATVIISGTKEEKLAKLKADLTERCIVRKCN CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCC ILDYQDCNNMIEEIPKLDVLICCAGITNDQLAIKMEVAKFETVISTNLTATFILNKAAIK CCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEHHHHHHHHHCCCEEEEEECHHHHH KMIKERYGRIINISSVVAISGNQGQSNYCASKAGIIGMSKALALEVASRNITVNVIAPGF HHHHHHCCCEEEEEEEEEEECCCCCCCHHHHHCCCEEHHHHHEEEEECCCEEEEEEECCH IISNMTNLLNEQQKNTILSKIPVNRFGNPNDIATAAAFLASRQAAYISGQTLHVNGGMVM HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCEEECCCEEEECCCEEE V C
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11557893 [H]