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The map label for this gene is secA2 [H]

Identifier: 189183925

GI number: 189183925

Start: 1061976

End: 1063418

Strand: Direct

Name: secA2 [H]

Synonym: OTT_1018

Alternate gene names: 189183925

Gene position: 1061976-1063418 (Clockwise)

Preceding gene: 189183924

Following gene: 189183926

Centisome position: 52.86

GC content: 31.46

Gene sequence:

>1443_bases
ATGCTAATTGACGAACTTGATCAAACAGCGAGATTAGCTCGATCTGTGCCTGGAATGGAGCATATAGCACCTATATTATG
CGGAGTAGCAAGTGAATTATCCAATTTAAATAAAAAAATAATACAGCAAGGCGATAAAACAATATATATAAATGGAGAGT
TCGAATATAAAGATGGAGAACTAATTTTAGGAAAAGATAGTAGTGAATATTATATCAGTGATCACTATGCTTTTGTTATT
GGAATTTTAAAGGATCTGATTCAAGAGATGGTTACTGGCGGTGAACTGCAAGTACCTAATTTCTTAAAAGATTTTATTCT
ATATCAGTCGGAAGTTATTGCATCTTCAGCATTTCAAGCACAGTTTTTCAAAGAGAATGAAGATTATATAATTGCTAAGA
GAGATAATGATAATTTAGATATTATTCCAGTTGATTATGTAAGTACAGGAATAATAAGATCAAATTGCCATTGGAATAAT
TTTTTTCATCAATTTCTTCAGATAAAGCATGGGTTAAAACTAACATCAGAAAATTTAGTCACAAGTTTTATTTCTAATTT
AGGATATTTCAAACATTATGGACAAAAGATATATGGTATGACAGGTACCATTGGGTCTGATTCTGCTCAAGAACTAGTAC
GTTCTGTATATGGAGTAAATATTGGGTTTATGCCAACTTATAAACCAAAACAATTTGAAGAAATTGATGGAGATATACAA
AACAATGAAACAACATGGCATGGTAGAATAACAAGTAGCATACTTGATGAAGCTGAAAAAGGAAGAGCTGTACTTGTTAT
TTGTGCAACAATCAAAGATGCGATAGAGATTCGTGAACGCTTCATTTCAGTTGTTGGCTATGATTCAGATAAAGTAAGAT
TATATTCTCGAAATGATAATGATGAGTATTTAGCAGTCAAAGATGAAGTGAATTCAGGAGATGTAATAGTAGCAACAAAT
TTAGCAGGACGAGGTACAGATATAAAGACGAGTGAAGAAGTTGAAAAGAATGGTGGTTTACATGTAATAGTTACTTTTTT
GCCTGAAAATTTGAGAGTAGAAGAACAAGCATTTGGTAGAACTGCAAGACAGGGAGCAAAAGGTACAGCACAACTAATAA
TATCTGAACCGAATGTTGCTCATAAATTCGAGATAAAATCGTATTCATATAATAGCATAAATGAATTTAAAGTATTGAGA
AACTGTAAGGAGTATATCAAAACACAAGAGACCAAATTATACGTGGTAGAAAAAATAAAATTACAAGATTTATTATTTGA
GGAGTATTTAAAGATTGAGTGCAATGTGCGTAATGCAATACAAAATCGGTGGCAAGTTTTGCAATTAGAAGACATTTGGG
AAATAGAGTTAACCAAACTAGGAAATTTAGTATATAAGAATCATAAAGCACAAAAAGGATTACAAAATATGGCCTCCCAG
TAA

Upstream 100 bases:

>100_bases
ACATGAATTTCAGTTCGATTGGTTAAGGCATGAACATAAGAAATATGGTACACGAGGTGATAGAGAATTTGGAGTAGTAA
TTGTAGACGAAGTGGATAGC

Downstream 100 bases:

>100_bases
GTTACAAAAGACAATAGTAAGTTCATGCAAAACCCTAACTACTTGGTTAGAGAAGCATAATAAGTGGGTATAAAGACAAT
GAATATAGCAAGTCATTCAT

Product: preprotein translocase SecA subunit-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MLIDELDQTARLARSVPGMEHIAPILCGVASELSNLNKKIIQQGDKTIYINGEFEYKDGELILGKDSSEYYISDHYAFVI
GILKDLIQEMVTGGELQVPNFLKDFILYQSEVIASSAFQAQFFKENEDYIIAKRDNDNLDIIPVDYVSTGIIRSNCHWNN
FFHQFLQIKHGLKLTSENLVTSFISNLGYFKHYGQKIYGMTGTIGSDSAQELVRSVYGVNIGFMPTYKPKQFEEIDGDIQ
NNETTWHGRITSSILDEAEKGRAVLVICATIKDAIEIRERFISVVGYDSDKVRLYSRNDNDEYLAVKDEVNSGDVIVATN
LAGRGTDIKTSEEVEKNGGLHVIVTFLPENLRVEEQAFGRTARQGAKGTAQLIISEPNVAHKFEIKSYSYNSINEFKVLR
NCKEYIKTQETKLYVVEKIKLQDLLFEEYLKIECNVRNAIQNRWQVLQLEDIWEIELTKLGNLVYKNHKAQKGLQNMASQ

Sequences:

>Translated_480_residues
MLIDELDQTARLARSVPGMEHIAPILCGVASELSNLNKKIIQQGDKTIYINGEFEYKDGELILGKDSSEYYISDHYAFVI
GILKDLIQEMVTGGELQVPNFLKDFILYQSEVIASSAFQAQFFKENEDYIIAKRDNDNLDIIPVDYVSTGIIRSNCHWNN
FFHQFLQIKHGLKLTSENLVTSFISNLGYFKHYGQKIYGMTGTIGSDSAQELVRSVYGVNIGFMPTYKPKQFEEIDGDIQ
NNETTWHGRITSSILDEAEKGRAVLVICATIKDAIEIRERFISVVGYDSDKVRLYSRNDNDEYLAVKDEVNSGDVIVATN
LAGRGTDIKTSEEVEKNGGLHVIVTFLPENLRVEEQAFGRTARQGAKGTAQLIISEPNVAHKFEIKSYSYNSINEFKVLR
NCKEYIKTQETKLYVVEKIKLQDLLFEEYLKIECNVRNAIQNRWQVLQLEDIWEIELTKLGNLVYKNHKAQKGLQNMASQ
>Mature_480_residues
MLIDELDQTARLARSVPGMEHIAPILCGVASELSNLNKKIIQQGDKTIYINGEFEYKDGELILGKDSSEYYISDHYAFVI
GILKDLIQEMVTGGELQVPNFLKDFILYQSEVIASSAFQAQFFKENEDYIIAKRDNDNLDIIPVDYVSTGIIRSNCHWNN
FFHQFLQIKHGLKLTSENLVTSFISNLGYFKHYGQKIYGMTGTIGSDSAQELVRSVYGVNIGFMPTYKPKQFEEIDGDIQ
NNETTWHGRITSSILDEAEKGRAVLVICATIKDAIEIRERFISVVGYDSDKVRLYSRNDNDEYLAVKDEVNSGDVIVATN
LAGRGTDIKTSEEVEKNGGLHVIVTFLPENLRVEEQAFGRTARQGAKGTAQLIISEPNVAHKFEIKSYSYNSINEFKVLR
NCKEYIKTQETKLYVVEKIKLQDLLFEEYLKIECNVRNAIQNRWQVLQLEDIWEIELTKLGNLVYKNHKAQKGLQNMASQ

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=291, Percent_Identity=26.8041237113402, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 54670; Mature: 54670

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDELDQTARLARSVPGMEHIAPILCGVASELSNLNKKIIQQGDKTIYINGEFEYKDGE
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCC
LILGKDSSEYYISDHYAFVIGILKDLIQEMVTGGELQVPNFLKDFILYQSEVIASSAFQA
EEEECCCCCEEECCHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHH
QFFKENEDYIIAKRDNDNLDIIPVDYVSTGIIRSNCHWNNFFHQFLQIKHGLKLTSENLV
HHHCCCCCEEEEECCCCCEEEEEECHHCCCEEECCCCHHHHHHHHHHHHCCCEECHHHHH
TSFISNLGYFKHYGQKIYGMTGTIGSDSAQELVRSVYGVNIGFMPTYKPKQFEEIDGDIQ
HHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCC
NNETTWHGRITSSILDEAEKGRAVLVICATIKDAIEIRERFISVVGYDSDKVRLYSRNDN
CCCEEEECHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
DEYLAVKDEVNSGDVIVATNLAGRGTDIKTSEEVEKNGGLHVIVTFLPENLRVEEQAFGR
CCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCHHHHHCH
TARQGAKGTAQLIISEPNVAHKFEIKSYSYNSINEFKVLRNCKEYIKTQETKLYVVEKIK
HHHCCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHH
LQDLLFEEYLKIECNVRNAIQNRWQVLQLEDIWEIELTKLGNLVYKNHKAQKGLQNMASQ
HHHHHHHHHHEEEECHHHHHHCCEEEEEECCCCEEHHHHHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MLIDELDQTARLARSVPGMEHIAPILCGVASELSNLNKKIIQQGDKTIYINGEFEYKDGE
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCC
LILGKDSSEYYISDHYAFVIGILKDLIQEMVTGGELQVPNFLKDFILYQSEVIASSAFQA
EEEECCCCCEEECCHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHH
QFFKENEDYIIAKRDNDNLDIIPVDYVSTGIIRSNCHWNNFFHQFLQIKHGLKLTSENLV
HHHCCCCCEEEEECCCCCEEEEEECHHCCCEEECCCCHHHHHHHHHHHHCCCEECHHHHH
TSFISNLGYFKHYGQKIYGMTGTIGSDSAQELVRSVYGVNIGFMPTYKPKQFEEIDGDIQ
HHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCC
NNETTWHGRITSSILDEAEKGRAVLVICATIKDAIEIRERFISVVGYDSDKVRLYSRNDN
CCCEEEECHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCC
DEYLAVKDEVNSGDVIVATNLAGRGTDIKTSEEVEKNGGLHVIVTFLPENLRVEEQAFGR
CCEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHCCCEEEEEEECCCCCCCHHHHHCH
TARQGAKGTAQLIISEPNVAHKFEIKSYSYNSINEFKVLRNCKEYIKTQETKLYVVEKIK
HHHCCCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEHHH
LQDLLFEEYLKIECNVRNAIQNRWQVLQLEDIWEIELTKLGNLVYKNHKAQKGLQNMASQ
HHHHHHHHHHEEEECHHHHHHCCEEEEEECCCCEEHHHHHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA