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The map label for this gene is atpA [H]

Identifier: 189183875

GI number: 189183875

Start: 1014660

End: 1016198

Strand: Direct

Name: atpA [H]

Synonym: OTT_0968

Alternate gene names: 189183875

Gene position: 1014660-1016198 (Clockwise)

Preceding gene: 189183874

Following gene: 189183876

Centisome position: 50.51

GC content: 33.66

Gene sequence:

>1539_bases
ATGCAACTAAAAGCCTCAGAGGTTTACGAAGCGTTAAAAAAACAGTTAGAAGATTTTGATGAATTATCAGAATTATCTGA
AGTAGGATATGTAATATCTATTGGTGATGGAATAGCTAAAGTTTATGGTCTTAGTAATGCTTACTCAGGGGAGATTTTAC
AGTTTTCTACAGGAACCAAAGGTATAGTTTTTAGTTTAAAGGATAATTTGATAGAAGCAGTAGTTATTGGTAGTGATGAT
CAGATTAAGCAAGGAAGTCAAGTAAAACGCACTCAAACATCTTTAAAAGTACCTACTGGAAAAGAGTTACTAGGAAGAGT
AGTTGATGCTGTTGGTAATCCTATAGATGGTAAAGGTGAATTTATTAATCCTACATATTTAGATGTTGAAGTCAAAGCTC
CAAGCGTTATGTGTAGGGATAGTGTTAATGAGCCTATGTATACTGGTATTAAAGCTATTGATGCTTTAATACCTATTGGT
AAAGGGCAAAGAGAATTAATTATTGGAGATAGGCAGACAGGCAAAACTGCTATAGCTATCGATATCATTCTTAACCAAAA
AAGATTTCATCTTTCAGATCAGGAAAGAGAAAAGGTTTATTGTATATATGTAGCAATTGGGCAAAAACGTTCAACTGTTG
CTCAGTTAGTTAAAAAATTACAAGAAACAGGCGCAATGGCTTACACTACAGTTGTATTATCTAGTGCATCCGATGCTGCT
TCATTACAATATTTAGCCCCTTATACTGGTTGTGCTATTGGAGAATATTTTAGGGATAACGGTATGCATGCTTTAGTTAT
TTATGATGATTTAAGTAAGCATGCTATAGCTTATCGACAAATATCCTTGTTATTAAGAAGGCCTCCAGCTCGGGAAGCTT
ACCCTGGTGATGTATTTTATCTTCATTCAAGACTGTTAGAAAGAGCAGCAAAATTGAATAAAGCTAAGGGGGAGGGGTCA
TTGACTGCATTACCTATTGTTGAAACCCAAAATAGTGATGTGTCTGCTTATATTCCTACTAATATTATTTCTATTACTGA
TGGACAAATTTTCTTAGAGAGTGAATTATTTTATAAAGGTACAAAACCAGCATTAAATGTTGGTATCTCTGTTAGCAGAG
TTGGAGCTGCAGCTCAAATTAAGGCTATGAAGGATATAGCTGGTACTGTTAAGCTGGAACTTGCGCAATATCATGAAATG
GAAGCTTTTTCTCAGTTTGGTGCAGATCTTGATTCTAGTAGTATGCAATTAATAAATAGGGGACGAAGGTTAAGTGAATT
GCTAAAGCAGTCGCAATATTGTCCATTTTCAGTCGAAGAACAAATTATTGTATTGTTTGCAGGAATCAATGGTTATTTGG
ATAAGGTAGCAGTAAGTAAAGTGAAAGAATTTGAGAGTAATATGTTGGAACATTTTAGAATACACAATCCAGATATTATG
AATGAAATTATCAGCACAAAAAAAATTACTGAAATTATTAGTAGCAAATTACACCAGATTTTGCAAGAATTTGTAAAATC
TATTGAACAGTATAGTTAG

Upstream 100 bases:

>100_bases
TCTTTCTATGCTAGGAGCTATCAATAGGTTTAAATCTCGTATTAAGTTAAATTATTAGATTAGTACAAAAAAAGTTATTT
TAATAAAGAATAGGTATTAA

Downstream 100 bases:

>100_bases
GAGCAAAAGCTTGCATGACAGTTCTTAAGCAATTGAGGGATAGAATTAAAGCTGTTCGATCTACTCAAAAAGTTACTAAA
GCAATGCAGTTAATTGCTAG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MQLKASEVYEALKKQLEDFDELSELSEVGYVISIGDGIAKVYGLSNAYSGEILQFSTGTKGIVFSLKDNLIEAVVIGSDD
QIKQGSQVKRTQTSLKVPTGKELLGRVVDAVGNPIDGKGEFINPTYLDVEVKAPSVMCRDSVNEPMYTGIKAIDALIPIG
KGQRELIIGDRQTGKTAIAIDIILNQKRFHLSDQEREKVYCIYVAIGQKRSTVAQLVKKLQETGAMAYTTVVLSSASDAA
SLQYLAPYTGCAIGEYFRDNGMHALVIYDDLSKHAIAYRQISLLLRRPPAREAYPGDVFYLHSRLLERAAKLNKAKGEGS
LTALPIVETQNSDVSAYIPTNIISITDGQIFLESELFYKGTKPALNVGISVSRVGAAAQIKAMKDIAGTVKLELAQYHEM
EAFSQFGADLDSSSMQLINRGRRLSELLKQSQYCPFSVEEQIIVLFAGINGYLDKVAVSKVKEFESNMLEHFRIHNPDIM
NEIISTKKITEIISSKLHQILQEFVKSIEQYS

Sequences:

>Translated_512_residues
MQLKASEVYEALKKQLEDFDELSELSEVGYVISIGDGIAKVYGLSNAYSGEILQFSTGTKGIVFSLKDNLIEAVVIGSDD
QIKQGSQVKRTQTSLKVPTGKELLGRVVDAVGNPIDGKGEFINPTYLDVEVKAPSVMCRDSVNEPMYTGIKAIDALIPIG
KGQRELIIGDRQTGKTAIAIDIILNQKRFHLSDQEREKVYCIYVAIGQKRSTVAQLVKKLQETGAMAYTTVVLSSASDAA
SLQYLAPYTGCAIGEYFRDNGMHALVIYDDLSKHAIAYRQISLLLRRPPAREAYPGDVFYLHSRLLERAAKLNKAKGEGS
LTALPIVETQNSDVSAYIPTNIISITDGQIFLESELFYKGTKPALNVGISVSRVGAAAQIKAMKDIAGTVKLELAQYHEM
EAFSQFGADLDSSSMQLINRGRRLSELLKQSQYCPFSVEEQIIVLFAGINGYLDKVAVSKVKEFESNMLEHFRIHNPDIM
NEIISTKKITEIISSKLHQILQEFVKSIEQYS
>Mature_512_residues
MQLKASEVYEALKKQLEDFDELSELSEVGYVISIGDGIAKVYGLSNAYSGEILQFSTGTKGIVFSLKDNLIEAVVIGSDD
QIKQGSQVKRTQTSLKVPTGKELLGRVVDAVGNPIDGKGEFINPTYLDVEVKAPSVMCRDSVNEPMYTGIKAIDALIPIG
KGQRELIIGDRQTGKTAIAIDIILNQKRFHLSDQEREKVYCIYVAIGQKRSTVAQLVKKLQETGAMAYTTVVLSSASDAA
SLQYLAPYTGCAIGEYFRDNGMHALVIYDDLSKHAIAYRQISLLLRRPPAREAYPGDVFYLHSRLLERAAKLNKAKGEGS
LTALPIVETQNSDVSAYIPTNIISITDGQIFLESELFYKGTKPALNVGISVSRVGAAAQIKAMKDIAGTVKLELAQYHEM
EAFSQFGADLDSSSMQLINRGRRLSELLKQSQYCPFSVEEQIIVLFAGINGYLDKVAVSKVKEFESNMLEHFRIHNPDIM
NEIISTKKITEIISSKLHQILQEFVKSIEQYS

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=61.5079365079365, Blast_Score=645, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=61.5079365079365, Blast_Score=645, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=335, Percent_Identity=27.4626865671642, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI19913426, Length=335, Percent_Identity=26.865671641791, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI32189394, Length=398, Percent_Identity=24.1206030150754, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI19913424, Length=248, Percent_Identity=28.6290322580645, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1790172, Length=516, Percent_Identity=52.7131782945737, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI1790170, Length=423, Percent_Identity=24.113475177305, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788251, Length=290, Percent_Identity=29.3103448275862, Blast_Score=112, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI71988063, Length=505, Percent_Identity=60.1980198019802, Blast_Score=639, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=505, Percent_Identity=60.1980198019802, Blast_Score=638, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=505, Percent_Identity=56.4356435643564, Blast_Score=588, Evalue=1e-168,
Organism=Caenorhabditis elegans, GI17510931, Length=293, Percent_Identity=28.6689419795222, Blast_Score=118, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=287, Percent_Identity=27.1777003484321, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=396, Percent_Identity=24.2424242424242, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17565854, Length=260, Percent_Identity=28.0769230769231, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=70, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319370, Length=505, Percent_Identity=56.2376237623762, Blast_Score=617, Evalue=1e-177,
Organism=Saccharomyces cerevisiae, GI6319603, Length=298, Percent_Identity=29.5302013422819, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6322581, Length=397, Percent_Identity=25.4408060453401, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24658560, Length=506, Percent_Identity=59.6837944664032, Blast_Score=644, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=336, Percent_Identity=26.4880952380952, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646341, Length=336, Percent_Identity=26.4880952380952, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136796, Length=336, Percent_Identity=26.4880952380952, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28574560, Length=412, Percent_Identity=25.9708737864078, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24638766, Length=398, Percent_Identity=23.8693467336683, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24583992, Length=274, Percent_Identity=28.1021897810219, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583988, Length=274, Percent_Identity=28.1021897810219, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24583986, Length=274, Percent_Identity=28.1021897810219, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24583984, Length=274, Percent_Identity=28.1021897810219, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI20129479, Length=262, Percent_Identity=28.2442748091603, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 56531; Mature: 56531

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKASEVYEALKKQLEDFDELSELSEVGYVISIGDGIAKVYGLSNAYSGEILQFSTGTK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHCCCCCCCCCEEEECCCCC
GIVFSLKDNLIEAVVIGSDDQIKQGSQVKRTQTSLKVPTGKELLGRVVDAVGNPIDGKGE
CEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
FINPTYLDVEVKAPSVMCRDSVNEPMYTGIKAIDALIPIGKGQRELIIGDRQTGKTAIAI
CCCCEEEEEEECCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEE
DIILNQKRFHLSDQEREKVYCIYVAIGQKRSTVAQLVKKLQETGAMAYTTVVLSSASDAA
EEEECCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCC
SLQYLAPYTGCAIGEYFRDNGMHALVIYDDLSKHAIAYRQISLLLRRPPAREAYPGDVFY
CEEEECCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
LHSRLLERAAKLNKAKGEGSLTALPIVETQNSDVSAYIPTNIISITDGQIFLESELFYKG
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEECCEEEEEECCEEEEECCCEECC
TKPALNVGISVSRVGAAAQIKAMKDIAGTVKLELAQYHEMEAFSQFGADLDSSSMQLINR
CCCHHCCCEEHHHCCCHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCCCCCHHHHHHHC
GRRLSELLKQSQYCPFSVEEQIIVLFAGINGYLDKVAVSKVKEFESNMLEHFRIHNPDIM
CHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
NEIISTKKITEIISSKLHQILQEFVKSIEQYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLKASEVYEALKKQLEDFDELSELSEVGYVISIGDGIAKVYGLSNAYSGEILQFSTGTK
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHCCCCCCCCCEEEECCCCC
GIVFSLKDNLIEAVVIGSDDQIKQGSQVKRTQTSLKVPTGKELLGRVVDAVGNPIDGKGE
CEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
FINPTYLDVEVKAPSVMCRDSVNEPMYTGIKAIDALIPIGKGQRELIIGDRQTGKTAIAI
CCCCEEEEEEECCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEE
DIILNQKRFHLSDQEREKVYCIYVAIGQKRSTVAQLVKKLQETGAMAYTTVVLSSASDAA
EEEECCCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCC
SLQYLAPYTGCAIGEYFRDNGMHALVIYDDLSKHAIAYRQISLLLRRPPAREAYPGDVFY
CEEEECCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
LHSRLLERAAKLNKAKGEGSLTALPIVETQNSDVSAYIPTNIISITDGQIFLESELFYKG
HHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEECCEEEEEECCEEEEECCCEECC
TKPALNVGISVSRVGAAAQIKAMKDIAGTVKLELAQYHEMEAFSQFGADLDSSSMQLINR
CCCHHCCCEEHHHCCCHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCCCCCHHHHHHHC
GRRLSELLKQSQYCPFSVEEQIIVLFAGINGYLDKVAVSKVKEFESNMLEHFRIHNPDIM
CHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
NEIISTKKITEIISSKLHQILQEFVKSIEQYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA