Click here to switch to the map view.

The map label for this gene is tlc1 [H]

Identifier: 189183706

GI number: 189183706

Start: 842108

End: 843583

Strand: Direct

Name: tlc1 [H]

Synonym: OTT_0799

Alternate gene names: 189183706

Gene position: 842108-843583 (Clockwise)

Preceding gene: 189183705

Following gene: 189183710

Centisome position: 41.92

GC content: 29.95

Gene sequence:

>1476_bases
ATGAATACAAATCAAACATTTAATAAGCTTCGCCAAATTTTTTGGCCTATTGAATATCATGAAAACAAGAAATTTTTGCC
TATGGCACTAATGATGTTTTTTATACTATTTAACTACTCAGCATTACGCTCTATTAAAGATAGTTTAGTAATAACAAGCA
TTGGTCCGGAAGTAATTAGTTTTTTAAAGACATACATAGTATTGCCATCAGCTATTATTGCGATGTTAATATATACAAAA
TTATGCAATGTAATGAATGTGACAAAAGTGTTCTATACTATCACATCTTTTTTTCTTGGCTATTTAATTTTATTTGTTAT
AGTACTCTATCCTAATACGCAGTTAGTACATCCAGCTCCTGAAACTATTGTAAAACTTAGTACAAATTATCCAAATTTTC
AATGGTTTATTAAAATTATAGGGCAATGGAGTTATGCAAGTTTTTATGCTATAGCTGAGTTATGGGGAAGCGTTATGCTT
ACATTACTCTTTTGGCAATTTGCGAATCAAATTACTAAAACAGAAGAAGCGAAAAGGTTTTATTCAATGTTTGGATTATT
AGGAAATTTTTCGCTTCTCTTAACTGGGTATATGCTAGAGCATTTTTTAAGCGAAAATAGCATAATTAATGCTGAGCTTA
AATATACTCCAGTAATAACTACATGTATTATAGCTGGAGTATTTATTATATTAACTTATGCATATATCAACAACTATGTT
TTATCTGATCCTAAGCTATATAACCCATCAATACAAAAAACAACTAAGAAGAAGGCTAAGTTATCAATGCTAGAAAGTAT
CAAGTTGATTTTTTCATCAAAATATCTTGGTTTGATAGTTATATTAGTGCTTTCATATGGTATATCAATTAACTTAGTAG
AAGGTGTATGGAAAGCTAAAGCTAGAGAGCTGTATCCAACGCCAGAAGCATATGGAATGTTTATGGGAAATTTTCAAAAA
TGGCAAGGAACCGTAGCAATATTATTTATGATAGTTGGTAGCAATATTTTAAGACAAGTATCATGGTATACTGCAGCAAT
ATTTACTCCTTTAATGATTTTAATTACAGGATTAGCATTTTTTGGATTTATCTTCTTAGGAGACTCAATTTCATTATATG
TTACTGGAATTGCTCCACTATCTATTGCAGTTGCTATTGGAACAATGCAAAACGTACTAAGTAAAGCTACAAAATATTCT
TTGTTTGATTCCACTAAAGAAATGGCATATATTCCTCTTGATCATGAATTAAAAACTAAAGGAAAAGCAGCTGTAGATAT
TATCGGTGGAAGGCTTGGAAAATCTGGTGGAGGAGTTATACAATCAACCTTTTTTATGTTATTGCCAAGTTTTAGTTTTG
TTGAAGCTTCTCCTTATTTTGGTGCTATATTCTTTCTAGTAGTAATACTATGGATTTATTCTGTTGCAATGTTAAATCGT
AAGTATACTGAAGCAATAGCTATATCTAGTAACTAA

Upstream 100 bases:

>100_bases
CTATTATATTTAACACTAAGTAACAATGGTTATTGTTGTTCTATTTTGTTAATTGTTATATCTTTATTGCAAAAAAATTA
AATTTAAATTGATACCCGGA

Downstream 100 bases:

>100_bases
TATCCACAAGATAGGTCAAGATAAGTATCTTGACTGATCTTAAAAATTAAAGAATCAATAAACCAATAGATAGAATCATA
TTTCAAATTTCAAATACAAG

Product: ADP,ATP carrier protein homolog

Products: NA

Alternate protein names: ADP/ATP translocase 1 [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MNTNQTFNKLRQIFWPIEYHENKKFLPMALMMFFILFNYSALRSIKDSLVITSIGPEVISFLKTYIVLPSAIIAMLIYTK
LCNVMNVTKVFYTITSFFLGYLILFVIVLYPNTQLVHPAPETIVKLSTNYPNFQWFIKIIGQWSYASFYAIAELWGSVML
TLLFWQFANQITKTEEAKRFYSMFGLLGNFSLLLTGYMLEHFLSENSIINAELKYTPVITTCIIAGVFIILTYAYINNYV
LSDPKLYNPSIQKTTKKKAKLSMLESIKLIFSSKYLGLIVILVLSYGISINLVEGVWKAKARELYPTPEAYGMFMGNFQK
WQGTVAILFMIVGSNILRQVSWYTAAIFTPLMILITGLAFFGFIFLGDSISLYVTGIAPLSIAVAIGTMQNVLSKATKYS
LFDSTKEMAYIPLDHELKTKGKAAVDIIGGRLGKSGGGVIQSTFFMLLPSFSFVEASPYFGAIFFLVVILWIYSVAMLNR
KYTEAIAISSN

Sequences:

>Translated_491_residues
MNTNQTFNKLRQIFWPIEYHENKKFLPMALMMFFILFNYSALRSIKDSLVITSIGPEVISFLKTYIVLPSAIIAMLIYTK
LCNVMNVTKVFYTITSFFLGYLILFVIVLYPNTQLVHPAPETIVKLSTNYPNFQWFIKIIGQWSYASFYAIAELWGSVML
TLLFWQFANQITKTEEAKRFYSMFGLLGNFSLLLTGYMLEHFLSENSIINAELKYTPVITTCIIAGVFIILTYAYINNYV
LSDPKLYNPSIQKTTKKKAKLSMLESIKLIFSSKYLGLIVILVLSYGISINLVEGVWKAKARELYPTPEAYGMFMGNFQK
WQGTVAILFMIVGSNILRQVSWYTAAIFTPLMILITGLAFFGFIFLGDSISLYVTGIAPLSIAVAIGTMQNVLSKATKYS
LFDSTKEMAYIPLDHELKTKGKAAVDIIGGRLGKSGGGVIQSTFFMLLPSFSFVEASPYFGAIFFLVVILWIYSVAMLNR
KYTEAIAISSN
>Mature_491_residues
MNTNQTFNKLRQIFWPIEYHENKKFLPMALMMFFILFNYSALRSIKDSLVITSIGPEVISFLKTYIVLPSAIIAMLIYTK
LCNVMNVTKVFYTITSFFLGYLILFVIVLYPNTQLVHPAPETIVKLSTNYPNFQWFIKIIGQWSYASFYAIAELWGSVML
TLLFWQFANQITKTEEAKRFYSMFGLLGNFSLLLTGYMLEHFLSENSIINAELKYTPVITTCIIAGVFIILTYAYINNYV
LSDPKLYNPSIQKTTKKKAKLSMLESIKLIFSSKYLGLIVILVLSYGISINLVEGVWKAKARELYPTPEAYGMFMGNFQK
WQGTVAILFMIVGSNILRQVSWYTAAIFTPLMILITGLAFFGFIFLGDSISLYVTGIAPLSIAVAIGTMQNVLSKATKYS
LFDSTKEMAYIPLDHELKTKGKAAVDIIGGRLGKSGGGVIQSTFFMLLPSFSFVEASPYFGAIFFLVVILWIYSVAMLNR
KYTEAIAISSN

Specific function: Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism [H]

COG id: COG3202

COG function: function code C; ATP/ADP translocase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADP/ATP translocase tlc family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004667
- InterPro:   IPR016196 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 55529; Mature: 55529

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00310 LAMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTNQTFNKLRQIFWPIEYHENKKFLPMALMMFFILFNYSALRSIKDSLVITSIGPEVIS
CCCCHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHH
FLKTYIVLPSAIIAMLIYTKLCNVMNVTKVFYTITSFFLGYLILFVIVLYPNTQLVHPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCC
ETIVKLSTNYPNFQWFIKIIGQWSYASFYAIAELWGSVMLTLLFWQFANQITKTEEAKRF
HHHEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSMFGLLGNFSLLLTGYMLEHFLSENSIINAELKYTPVITTCIIAGVFIILTYAYINNYV
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCEE
LSDPKLYNPSIQKTTKKKAKLSMLESIKLIFSSKYLGLIVILVLSYGISINLVEGVWKAK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEHHHHHHHHH
ARELYPTPEAYGMFMGNFQKWQGTVAILFMIVGSNILRQVSWYTAAIFTPLMILITGLAF
HHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGFIFLGDSISLYVTGIAPLSIAVAIGTMQNVLSKATKYSLFDSTKEMAYIPLDHELKTK
HHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHCC
GKAAVDIIGGRLGKSGGGVIQSTFFMLLPSFSFVEASPYFGAIFFLVVILWIYSVAMLNR
CCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
KYTEAIAISSN
HHHHEEEECCC
>Mature Secondary Structure
MNTNQTFNKLRQIFWPIEYHENKKFLPMALMMFFILFNYSALRSIKDSLVITSIGPEVIS
CCCCHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHH
FLKTYIVLPSAIIAMLIYTKLCNVMNVTKVFYTITSFFLGYLILFVIVLYPNTQLVHPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCC
ETIVKLSTNYPNFQWFIKIIGQWSYASFYAIAELWGSVMLTLLFWQFANQITKTEEAKRF
HHHEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YSMFGLLGNFSLLLTGYMLEHFLSENSIINAELKYTPVITTCIIAGVFIILTYAYINNYV
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCEE
LSDPKLYNPSIQKTTKKKAKLSMLESIKLIFSSKYLGLIVILVLSYGISINLVEGVWKAK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEHHHHHHHHH
ARELYPTPEAYGMFMGNFQKWQGTVAILFMIVGSNILRQVSWYTAAIFTPLMILITGLAF
HHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGFIFLGDSISLYVTGIAPLSIAVAIGTMQNVLSKATKYSLFDSTKEMAYIPLDHELKTK
HHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHCC
GKAAVDIIGGRLGKSGGGVIQSTFFMLLPSFSFVEASPYFGAIFFLVVILWIYSVAMLNR
CCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
KYTEAIAISSN
HHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA