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The map label for this gene is gcp [H]

Identifier: 189183651

GI number: 189183651

Start: 769299

End: 770333

Strand: Reverse

Name: gcp [H]

Synonym: OTT_0744

Alternate gene names: 189183651

Gene position: 770333-769299 (Counterclockwise)

Preceding gene: 189183652

Following gene: 189183650

Centisome position: 38.34

GC content: 33.62

Gene sequence:

>1035_bases
GTGAATGTTATTGGTATTGAGTCTAGTTGTGATGATACAGCTATTGCTATAGTTAATAGTAATAGAGAGATAATTGCTAA
TGTAGTAATTTCCCAATATACTGAACATCTTCCTTATAGCGGTGTAGTACCTGAAATTGCAGCTAGGGCTCATCTGAAAA
ATTTGCAATATGCTATGAAAGAGACTTTAAATCAAGCAAAGATTAATTTCACAGATATTGATGTAATTGCAGCTACATCT
GGGCCTGGTTTAATTGGAGGGGTAATAGTAGGCTCAGTATTTGGGCAGGCAATTGCATGTGCCTTAGGCAAAGATTTCAT
TGCAGTAAATCATTTAGAAGGGCATATACTAGCAGTGCGACTAAATGAGAACATTAGTTTCCCTTATTTGGTATTGCTTG
TTTCTGGAGGGCATTGCCAATTTATTGCAGTATTAGGAGTTGGTAAATATAAGATTTTAGGACAAACGATTGATGATGCT
GTTGGTGAAGCATTTGATAAAACAGCTAGACTATTAAAACTTGGATATCCTGGAGGACCAATCATTGAAAAATTAGCTAG
TAAAGGTGATCCTCACAAATATTCTTTACCATTGTCAATGACAAAGAAATCTGGCTGTGATCTATCATTTTCTGGATTAA
AAACAGCAGTTAAGCAATTAATATTTAGTATAGAATCTTTATCTGAAAAAGTAATTTGTGATATATGCGCTTCGTTTCAA
TACACTGTAGTTCAGATTCTACTGTGCCGTAGTATTAATGCTATTAAATTGTTTGAAAGTTATTGTAGCAATAATTTTAA
AATTAATAGGAAGAATTATTTTGTTATATCAGGAGGAGTAGCAGCTAATCAATATCTGAGACAAGAAATATTTAATTTAG
CTAGTACATATGGCTATTGCGGTGTTGCTCCGCCTAGCAATTTGTGTACTGATAATGCAGCAATGATAGCTTGGGCAGGA
ATAGAAAGATTAAACGCTAATCTATTTAGTAGTAATTTTGTTCCAAGAGCTAAATGGAGTGTTGAAGAACTTTAA

Upstream 100 bases:

>100_bases
CTATCTTGGAATCTTTAAAATATGAAGAAATAATTGAAAAGCTAACTGAAATCTTGAAAAATAGAAATACTGTATAATCA
ACATACATAAGAAGTTTATT

Downstream 100 bases:

>100_bases
TTTAATAGCCTCATGAATGTAAAGAACATAAGATATTTTACTTCTAACTTAGCTAGGTCTGCACAGATAGCAAATGAATT
ACAACAAAAATATAATATTC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNVIGIESSCDDTAIAIVNSNREIIANVVISQYTEHLPYSGVVPEIAARAHLKNLQYAMKETLNQAKINFTDIDVIAATS
GPGLIGGVIVGSVFGQAIACALGKDFIAVNHLEGHILAVRLNENISFPYLVLLVSGGHCQFIAVLGVGKYKILGQTIDDA
VGEAFDKTARLLKLGYPGGPIIEKLASKGDPHKYSLPLSMTKKSGCDLSFSGLKTAVKQLIFSIESLSEKVICDICASFQ
YTVVQILLCRSINAIKLFESYCSNNFKINRKNYFVISGGVAANQYLRQEIFNLASTYGYCGVAPPSNLCTDNAAMIAWAG
IERLNANLFSSNFVPRAKWSVEEL

Sequences:

>Translated_344_residues
MNVIGIESSCDDTAIAIVNSNREIIANVVISQYTEHLPYSGVVPEIAARAHLKNLQYAMKETLNQAKINFTDIDVIAATS
GPGLIGGVIVGSVFGQAIACALGKDFIAVNHLEGHILAVRLNENISFPYLVLLVSGGHCQFIAVLGVGKYKILGQTIDDA
VGEAFDKTARLLKLGYPGGPIIEKLASKGDPHKYSLPLSMTKKSGCDLSFSGLKTAVKQLIFSIESLSEKVICDICASFQ
YTVVQILLCRSINAIKLFESYCSNNFKINRKNYFVISGGVAANQYLRQEIFNLASTYGYCGVAPPSNLCTDNAAMIAWAG
IERLNANLFSSNFVPRAKWSVEEL
>Mature_344_residues
MNVIGIESSCDDTAIAIVNSNREIIANVVISQYTEHLPYSGVVPEIAARAHLKNLQYAMKETLNQAKINFTDIDVIAATS
GPGLIGGVIVGSVFGQAIACALGKDFIAVNHLEGHILAVRLNENISFPYLVLLVSGGHCQFIAVLGVGKYKILGQTIDDA
VGEAFDKTARLLKLGYPGGPIIEKLASKGDPHKYSLPLSMTKKSGCDLSFSGLKTAVKQLIFSIESLSEKVICDICASFQ
YTVVQILLCRSINAIKLFESYCSNNFKINRKNYFVISGGVAANQYLRQEIFNLASTYGYCGVAPPSNLCTDNAAMIAWAG
IERLNANLFSSNFVPRAKWSVEEL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=341, Percent_Identity=36.6568914956012, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI8923380, Length=326, Percent_Identity=31.9018404907975, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1789445, Length=347, Percent_Identity=40.9221902017291, Blast_Score=264, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI17557464, Length=350, Percent_Identity=32.2857142857143, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71995670, Length=327, Percent_Identity=32.1100917431193, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=374, Percent_Identity=31.8181818181818, Blast_Score=151, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322891, Length=321, Percent_Identity=32.398753894081, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI20129063, Length=342, Percent_Identity=36.8421052631579, Blast_Score=214, Evalue=6e-56,
Organism=Drosophila melanogaster, GI21357207, Length=332, Percent_Identity=30.1204819277108, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37199; Mature: 37199

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIGIESSCDDTAIAIVNSNREIIANVVISQYTEHLPYSGVVPEIAARAHLKNLQYAMK
CCEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ETLNQAKINFTDIDVIAATSGPGLIGGVIVGSVFGQAIACALGKDFIAVNHLEGHILAVR
HHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEE
LNENISFPYLVLLVSGGHCQFIAVLGVGKYKILGQTIDDAVGEAFDKTARLLKLGYPGGP
ECCCCCCCEEEEEEECCCEEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHEEECCCCCH
IIEKLASKGDPHKYSLPLSMTKKSGCDLSFSGLKTAVKQLIFSIESLSEKVICDICASFQ
HHHHHHCCCCCCEEECCEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTVVQILLCRSINAIKLFESYCSNNFKINRKNYFVISGGVAANQYLRQEIFNLASTYGYC
HHHHHHHHHCCCCHHHHHHHHHCCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHHCCCC
GVAPPSNLCTDNAAMIAWAGIERLNANLFSSNFVPRAKWSVEEL
CCCCCCCCCCCCCCEEEEHHHHHHCCHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNVIGIESSCDDTAIAIVNSNREIIANVVISQYTEHLPYSGVVPEIAARAHLKNLQYAMK
CCEECCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ETLNQAKINFTDIDVIAATSGPGLIGGVIVGSVFGQAIACALGKDFIAVNHLEGHILAVR
HHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEE
LNENISFPYLVLLVSGGHCQFIAVLGVGKYKILGQTIDDAVGEAFDKTARLLKLGYPGGP
ECCCCCCCEEEEEEECCCEEEEEEEECCCCEEECCHHHHHHHHHHHHHHHHEEECCCCCH
IIEKLASKGDPHKYSLPLSMTKKSGCDLSFSGLKTAVKQLIFSIESLSEKVICDICASFQ
HHHHHHCCCCCCEEECCEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTVVQILLCRSINAIKLFESYCSNNFKINRKNYFVISGGVAANQYLRQEIFNLASTYGYC
HHHHHHHHHCCCCHHHHHHHHHCCCEEEECCEEEEEECCHHHHHHHHHHHHHHHHHCCCC
GVAPPSNLCTDNAAMIAWAGIERLNANLFSSNFVPRAKWSVEEL
CCCCCCCCCCCCCCEEEEHHHHHHCCHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA