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The map label for this gene is ccmA [H]

Identifier: 189183633

GI number: 189183633

Start: 751316

End: 751921

Strand: Reverse

Name: ccmA [H]

Synonym: OTT_0726

Alternate gene names: 189183633

Gene position: 751921-751316 (Counterclockwise)

Preceding gene: 189183636

Following gene: 189183632

Centisome position: 37.43

GC content: 33.5

Gene sequence:

>606_bases
GTGCTCACTTGTCAAAATATATCACTTATATCATCCAATAATACAGTAATATTTGCCAATCTAAGCATTACTTTATTACC
TGGAGCCATAGCAATAATAAGAGGGAAAAATGGTGCTGGCAAAAGTTCATTATTAAAGATAATAGGTAACATACAATCTC
CAACAGCAGGCGAAGTATATATTCATAATATTCAAACTAATAAATTACAAAAGCCTTTTTTAGGGTACATAGGGCATCAA
CTAGGGTTAAAGCTTGACTTAACTGTGGAAGACAATTTAGTTATGTGGGCAAAATTTTATGATTCTGTAACTTTAATTCC
AGCGGCCGTAACATATTTTCGATTAACAGATTTCTTATCAGAAAAAGTATATAAATTGTCTAGCGGTATGAAGAAAAAAG
TAGCACTAGCACGCCTAATGGCATGTTACTCTAAAATATGGCTTCTTGACGAGGTAGAAACTAATTTAGATGAAGGAAAT
CGTAAATTAGTTTACAACTTGATAGCCATACACACTAATTCTGGTGGTATAGTATTATGGGCGTCGCATTCTCCATCACC
ATGGCCAAATGCACTGGAAGTTAATTTAGAGCAGTATAAAAAATGA

Upstream 100 bases:

>100_bases
GATTTTCATATAATTTAGTAAATTCACAAGTTTTAAAACCTTAATACTATAAAATTACTAGTGTTTTGAATGAATTAAAA
ACTAATCAATATAGCTTATA

Downstream 100 bases:

>100_bases
ATAGACTATTACTTTTATTAAAGCATGAAATATATATCTACCATAAAGTTTATACTATACCACAATACGTATTTATTCAT
GCTATAACGGCAATTTTAGC

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MLTCQNISLISSNNTVIFANLSITLLPGAIAIIRGKNGAGKSSLLKIIGNIQSPTAGEVYIHNIQTNKLQKPFLGYIGHQ
LGLKLDLTVEDNLVMWAKFYDSVTLIPAAVTYFRLTDFLSEKVYKLSSGMKKKVALARLMACYSKIWLLDEVETNLDEGN
RKLVYNLIAIHTNSGGIVLWASHSPSPWPNALEVNLEQYKK

Sequences:

>Translated_201_residues
MLTCQNISLISSNNTVIFANLSITLLPGAIAIIRGKNGAGKSSLLKIIGNIQSPTAGEVYIHNIQTNKLQKPFLGYIGHQ
LGLKLDLTVEDNLVMWAKFYDSVTLIPAAVTYFRLTDFLSEKVYKLSSGMKKKVALARLMACYSKIWLLDEVETNLDEGN
RKLVYNLIAIHTNSGGIVLWASHSPSPWPNALEVNLEQYKK
>Mature_201_residues
MLTCQNISLISSNNTVIFANLSITLLPGAIAIIRGKNGAGKSSLLKIIGNIQSPTAGEVYIHNIQTNKLQKPFLGYIGHQ
LGLKLDLTVEDNLVMWAKFYDSVTLIPAAVTYFRLTDFLSEKVYKLSSGMKKKVALARLMACYSKIWLLDEVETNLDEGN
RKLVYNLIAIHTNSGGIVLWASHSPSPWPNALEVNLEQYKK

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI45446740, Length=173, Percent_Identity=28.3236994219653, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI47078218, Length=173, Percent_Identity=28.3236994219653, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI87082064, Length=182, Percent_Identity=34.6153846153846, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI87081782, Length=173, Percent_Identity=30.0578034682081, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1786698, Length=194, Percent_Identity=29.8969072164948, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1789873, Length=196, Percent_Identity=26.530612244898, Blast_Score=70, Evalue=7e-14,
Organism=Escherichia coli, GI1790525, Length=181, Percent_Identity=27.6243093922652, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788761, Length=163, Percent_Identity=28.8343558282209, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87081791, Length=174, Percent_Identity=25.8620689655172, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI87081709, Length=178, Percent_Identity=24.1573033707865, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 22280; Mature: 22280

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTCQNISLISSNNTVIFANLSITLLPGAIAIIRGKNGAGKSSLLKIIGNIQSPTAGEVY
CEEECCEEEEECCCEEEEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEE
IHNIQTNKLQKPFLGYIGHQLGLKLDLTVEDNLVMWAKFYDSVTLIPAAVTYFRLTDFLS
EEECCCCCCCCHHHHHHHHHHCEEEEEEEECCEEEEEEHHCCEEHHHHHHHHHHHHHHHH
EKVYKLSSGMKKKVALARLMACYSKIWLLDEVETNLDEGNRKLVYNLIAIHTNSGGIVLW
HHHHHHHCCHHHHHHHHHHHHHHHHHHEEEHHHCCCCCCCEEEEEEEEEEEECCCCEEEE
ASHSPSPWPNALEVNLEQYKK
ECCCCCCCCCCEEECHHHHCC
>Mature Secondary Structure
MLTCQNISLISSNNTVIFANLSITLLPGAIAIIRGKNGAGKSSLLKIIGNIQSPTAGEVY
CEEECCEEEEECCCEEEEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHCCCCCCCCEEE
IHNIQTNKLQKPFLGYIGHQLGLKLDLTVEDNLVMWAKFYDSVTLIPAAVTYFRLTDFLS
EEECCCCCCCCHHHHHHHHHHCEEEEEEEECCEEEEEEHHCCEEHHHHHHHHHHHHHHHH
EKVYKLSSGMKKKVALARLMACYSKIWLLDEVETNLDEGNRKLVYNLIAIHTNSGGIVLW
HHHHHHHCCHHHHHHHHHHHHHHHHHHEEEHHHCCCCCCCEEEEEEEEEEEECCCCEEEE
ASHSPSPWPNALEVNLEQYKK
ECCCCCCCCCCEEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA