BacMap

Definition	Orientia tsutsugamushi str. Ikeda, complete genome.
Accession	NC_010793
Length	2,008,987

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The map label for this gene is fabG [H]

Identifier: 189183438

GI number: 189183438

Start: 553506

End: 554243

Strand: Reverse

Name: fabG [H]

Synonym: OTT_0531

Alternate gene names: 189183438

Gene position: 554243-553506 (Counterclockwise)

Preceding gene: 189183446

Following gene: 189183437

Centisome position: 27.59

GC content: 42.82

Gene sequence:

>738_bases
ATGCAACTATTTGATCTAAAAGGTAAAACAGCATTAATTACAGGAGCTTCAAGTGGTTTTGGGGAACAATTTGCCCGTTG
CCTATCTGGTGCAGTAGCACGCGTGATCTTGGCTGCTCGCAGGATTGATAAGTTGAACGACTTGGCTGCTGAGCTTAATA
ACGCTAGGGCAATCCAGATGGATGTATCAGACAAACAATCCGTAAAAAGTTGCTTTGCTGAGTTAGAAAAGGATGGTGAG
AAGATCGACATCTGCGTTAATAACGCTGGGATTGCAGCGCTTACTCCTATTTTTGAAGAAGATGATAACGATAATTTTGA
GTCCATTGTTCAAACGAACCTGATGGGCGTGTGGTACGTCACTAAGGCAGTGACAAACCACATGAAAAACCATGGCATTC
ATGGGGCAATTATTAATATCGGCAGTGTTAACGGTGATGCAATACCAGCAAAAAGAGGCGCTGCCTATTGTATCAGTAAG
GCTGCAGTCATTCACTTAACCAAAACCCTGGTTGGTGAACTATCTCCGCATAAGATAAGAGTCAACTGCATATCTCCAGG
CTGGTTTAGAACGCCCATGAATGGACCGGATATAGAACAAATCATTCCGTTTATTCCTTATGTGGATATTGCAGAACCTA
GGTACCTTGATGGACTGATACTATATCTTGCATCCAAAAATGCGTCTAAATATGTCACCGGTGCTACCTTCACTATAGAT
GGTGGCATGTCATGGTGA

Upstream 100 bases:

>100_bases
ATAACATGATTATACATATTATAGTTGTACAAAATATAGTTTTATGTCAAGATAAAGCTGTGGAAATCTCATAATTTTGT
CATCTGATGGAAAATTGAAC

Downstream 100 bases:

>100_bases
GGTAAATCGTAATGGATATAAAGATCAAACAAGTATGGTCTTACATAATAAGATCCGCCAAGCCATTCCCATTATCAATT
TTTGTTATGTTTCTCGTAGC

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: 3-dehydro-2-deoxy-D-gluconate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MQLFDLKGKTALITGASSGFGEQFARCLSGAVARVILAARRIDKLNDLAAELNNARAIQMDVSDKQSVKSCFAELEKDGE
KIDICVNNAGIAALTPIFEEDDNDNFESIVQTNLMGVWYVTKAVTNHMKNHGIHGAIINIGSVNGDAIPAKRGAAYCISK
AAVIHLTKTLVGELSPHKIRVNCISPGWFRTPMNGPDIEQIIPFIPYVDIAEPRYLDGLILYLASKNASKYVTGATFTID
GGMSW

Sequences:

>Translated_245_residues
MQLFDLKGKTALITGASSGFGEQFARCLSGAVARVILAARRIDKLNDLAAELNNARAIQMDVSDKQSVKSCFAELEKDGE
KIDICVNNAGIAALTPIFEEDDNDNFESIVQTNLMGVWYVTKAVTNHMKNHGIHGAIINIGSVNGDAIPAKRGAAYCISK
AAVIHLTKTLVGELSPHKIRVNCISPGWFRTPMNGPDIEQIIPFIPYVDIAEPRYLDGLILYLASKNASKYVTGATFTID
GGMSW
>Mature_245_residues
MQLFDLKGKTALITGASSGFGEQFARCLSGAVARVILAARRIDKLNDLAAELNNARAIQMDVSDKQSVKSCFAELEKDGE
KIDICVNNAGIAALTPIFEEDDNDNFESIVQTNLMGVWYVTKAVTNHMKNHGIHGAIINIGSVNGDAIPAKRGAAYCISK
AAVIHLTKTLVGELSPHKIRVNCISPGWFRTPMNGPDIEQIIPFIPYVDIAEPRYLDGLILYLASKNASKYVTGATFTID
GGMSW

Specific function: Proposed to modify Nod factor fatty acyl chain [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=30.6451612903226, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=28.9473684210526, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=30, Blast_Score=95, Evalue=5e-20,
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=27.9352226720648, Blast_Score=88, Evalue=5e-18,
Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=28.099173553719, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI59889578, Length=227, Percent_Identity=29.5154185022026, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI109715829, Length=236, Percent_Identity=27.9661016949153, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI31542939, Length=198, Percent_Identity=31.3131313131313, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4758504, Length=213, Percent_Identity=30.5164319248826, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=30.3482587064677, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=28.7937743190661, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI150247226, Length=199, Percent_Identity=30.6532663316583, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI50726952, Length=189, Percent_Identity=31.2169312169312, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=31.3953488372093, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI225579078, Length=206, Percent_Identity=28.1553398058252, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=25.609756097561, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI40548397, Length=199, Percent_Identity=29.1457286432161, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI214010158, Length=199, Percent_Identity=29.1457286432161, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI214010156, Length=199, Percent_Identity=29.1457286432161, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI22758144, Length=199, Percent_Identity=29.1457286432161, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4503301, Length=254, Percent_Identity=27.5590551181102, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI19743808, Length=192, Percent_Identity=27.6041666666667, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=26.8421052631579, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI186928839, Length=207, Percent_Identity=28.9855072463768, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI142976729, Length=209, Percent_Identity=25.8373205741627, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI87082100, Length=253, Percent_Identity=38.3399209486166, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=33.8645418326693, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=31.8367346938775, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=31.9502074688797, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787820, Length=177, Percent_Identity=35.5932203389831, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=29.9595141700405, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=30.3149606299213, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=28.2352941176471, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=28.8617886178862, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787905, Length=248, Percent_Identity=31.0483870967742, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1786812, Length=254, Percent_Identity=26.3779527559055, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=25.8196721311475, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=29.0983606557377, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=32.2834645669291, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=31.3207547169811, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=28.030303030303, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=27.6515151515151, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=29.8507462686567, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=29.5454545454545, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=31.8725099601594, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=26.4, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=27.2030651340996, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=29.9625468164794, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=28.0155642023346, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=27.1375464684015, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=27.4900398406374, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=26.9230769230769, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=25.6603773584906, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=28.125, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=28.125, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=26.1538461538462, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=26.0223048327138, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=30.859375, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=26.9961977186312, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=25.9541984732824, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=27.4436090225564, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=25.8687258687259, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=26.2172284644195, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=24.5967741935484, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=23.574144486692, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=258, Percent_Identity=27.5193798449612, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=36.1809045226131, Blast_Score=93, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320089, Length=195, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319635, Length=196, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=33.4661354581673, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=32.9411764705882, Blast_Score=103, Evalue=7e-23,
Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=32.6771653543307, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI23397609, Length=252, Percent_Identity=31.7460317460317, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281364494, Length=201, Percent_Identity=34.3283582089552, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=30.1960784313725, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI116007236, Length=214, Percent_Identity=31.7757009345794, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=28, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21358495, Length=199, Percent_Identity=34.1708542713568, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=30.7392996108949, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28571387, Length=199, Percent_Identity=33.6683417085427, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24584752, Length=193, Percent_Identity=31.0880829015544, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=28.7937743190661, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI116007238, Length=182, Percent_Identity=32.4175824175824, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24663911, Length=220, Percent_Identity=28.6363636363636, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=28.2722513089005, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=28.2722513089005, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24647946, Length=258, Percent_Identity=27.1317829457364, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI45553409, Length=258, Percent_Identity=27.1317829457364, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24647948, Length=258, Percent_Identity=27.1317829457364, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641388, Length=212, Percent_Identity=31.6037735849057, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641232, Length=210, Percent_Identity=30.4761904761905, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24644337, Length=173, Percent_Identity=33.5260115606936, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI116007234, Length=217, Percent_Identity=31.7972350230415, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24648693, Length=190, Percent_Identity=30, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355889, Length=190, Percent_Identity=30, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574402, Length=244, Percent_Identity=26.6393442622951, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24584744, Length=244, Percent_Identity=26.6393442622951, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=27.5510204081633, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28573296, Length=254, Percent_Identity=25.5905511811024, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007232, Length=185, Percent_Identity=30.8108108108108, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581726, Length=260, Percent_Identity=23.8461538461538, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.125

Molecular weight: Translated: 26544; Mature: 26544

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLFDLKGKTALITGASSGFGEQFARCLSGAVARVILAARRIDKLNDLAAELNNARAIQM
CCEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
DVSDKQSVKSCFAELEKDGEKIDICVNNAGIAALTPIFEEDDNDNFESIVQTNLMGVWYV
ECCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHH
TKAVTNHMKNHGIHGAIINIGSVNGDAIPAKRGAAYCISKAAVIHLTKTLVGELSPHKIR
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
VNCISPGWFRTPMNGPDIEQIIPFIPYVDIAEPRYLDGLILYLASKNASKYVTGATFTID
EEEECCCCEECCCCCCCHHHHHHHCCCCCCCCCCHHCEEEEEEECCCCCCEEECEEEEEC
GGMSW
CCCCC
>Mature Secondary Structure
MQLFDLKGKTALITGASSGFGEQFARCLSGAVARVILAARRIDKLNDLAAELNNARAIQM
CCEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
DVSDKQSVKSCFAELEKDGEKIDICVNNAGIAALTPIFEEDDNDNFESIVQTNLMGVWYV
ECCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHH
TKAVTNHMKNHGIHGAIINIGSVNGDAIPAKRGAAYCISKAAVIHLTKTLVGELSPHKIR
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEE
VNCISPGWFRTPMNGPDIEQIIPFIPYVDIAEPRYLDGLILYLASKNASKYVTGATFTID
EEEECCCCEECCCCCCCHHHHHHHCCCCCCCCCCHHCEEEEEEECCCCCCEEECEEEEEC
GGMSW
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-deoxy-D-gluconate; NAD+

Specific reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9100384 [H]