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The map label for this gene is sppA [C]

Identifier: 189182992

GI number: 189182992

Start: 89738

End: 90646

Strand: Direct

Name: sppA [C]

Synonym: OTT_0085

Alternate gene names: 189182992

Gene position: 89738-90646 (Clockwise)

Preceding gene: 189182991

Following gene: 189182993

Centisome position: 4.47

GC content: 31.9

Gene sequence:

>909_bases
ATGATAATTGATCCTGATTACTTAATTGAAAGAAAGTATTATAAAAGCCAATTAAAAAAGTGGAAGATTCTTACTTTGTT
GTTAATTACTGCTATAGTAGTGCTGTTTATTTTTCGAAATCGAGTAGGATATAGTCCATCATTAGCTACAGGTGATTATA
TTGCCAATATTCAAATTGATGATCTTATATATGATGATATAAAACTAAACAATTTATTACATCAAATTAAAAATGATGAT
AAAGCTAAAGCTTTAATATTACATGTAGATTCACCAGGTGGTACAGTAGCAGGTTCAGAAAAAATATATGGTATATTAAG
ATCCATTAGTAATAGCAAGCCTGTAGTTGCAGTATTAGGAACTGTCGCAGCCTCAGGTGGATATCTGGTTGCATTAGCAG
CAGATTATATTATTGCGCAAAAATCTACAGTAACTGGCTCTATAGGTATTGTGCATTTTTCTCCTGAAATTACTGAATTT
GGAGAAAAAATTGGAATAAAATTTCATACCTTTAAGTCTGGTGAGTTAAAAGCAGCACCTAGTTTAACTGAAAAAGTTAC
ACCAGCAGTTCATGAGGCCACTATGACGCTAATAAATGATATGTATGATTTTTTTGTTGAACTAGTAGCAGAGCGTAGAC
AAATGAGTCCAGAACAAGTATTAAAAGTTGCTGATGGCAAAGCATATACTGGTCGTCAAGCTTTATCTTTGAACTTAATT
GACGCATTAGGTACTACAGAGGATGCTTTAACCTGGCTGCAACAGGAAAAAAAGCTTTCTCTTGATCTTAGAGTAATAGA
ATTACATACGCAAACTAAGCTAGACAGCTATATTGAGTTATTTCAAAATAACATACGTAAATTGTTTTTTGGTAGTAAAA
TAAATGGTGTAATGGCATTGTATTGTTAA

Upstream 100 bases:

>100_bases
AAACAATATGATAAGCGTTATGCTATTAAAGAACAAGAATGGAAAAAACAACAAGCAAGAATAATGAGAAATAAGTTTTA
GTGGATGAAAAAAGTTTTAA

Downstream 100 bases:

>100_bases
GTTATTAATTATGTGTAGCGATAAGAATATTACAGCTACAGCCTTAGTAAGGCCTAGCTGGTTAAGAGTTAAAGCTCCTT
TTTCTGATGAGTATCAAAGT

Product: protease IV

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MIIDPDYLIERKYYKSQLKKWKILTLLLITAIVVLFIFRNRVGYSPSLATGDYIANIQIDDLIYDDIKLNNLLHQIKNDD
KAKALILHVDSPGGTVAGSEKIYGILRSISNSKPVVAVLGTVAASGGYLVALAADYIIAQKSTVTGSIGIVHFSPEITEF
GEKIGIKFHTFKSGELKAAPSLTEKVTPAVHEATMTLINDMYDFFVELVAERRQMSPEQVLKVADGKAYTGRQALSLNLI
DALGTTEDALTWLQQEKKLSLDLRVIELHTQTKLDSYIELFQNNIRKLFFGSKINGVMALYC

Sequences:

>Translated_302_residues
MIIDPDYLIERKYYKSQLKKWKILTLLLITAIVVLFIFRNRVGYSPSLATGDYIANIQIDDLIYDDIKLNNLLHQIKNDD
KAKALILHVDSPGGTVAGSEKIYGILRSISNSKPVVAVLGTVAASGGYLVALAADYIIAQKSTVTGSIGIVHFSPEITEF
GEKIGIKFHTFKSGELKAAPSLTEKVTPAVHEATMTLINDMYDFFVELVAERRQMSPEQVLKVADGKAYTGRQALSLNLI
DALGTTEDALTWLQQEKKLSLDLRVIELHTQTKLDSYIELFQNNIRKLFFGSKINGVMALYC
>Mature_302_residues
MIIDPDYLIERKYYKSQLKKWKILTLLLITAIVVLFIFRNRVGYSPSLATGDYIANIQIDDLIYDDIKLNNLLHQIKNDD
KAKALILHVDSPGGTVAGSEKIYGILRSISNSKPVVAVLGTVAASGGYLVALAADYIIAQKSTVTGSIGIVHFSPEITEF
GEKIGIKFHTFKSGELKAAPSLTEKVTPAVHEATMTLINDMYDFFVELVAERRQMSPEQVLKVADGKAYTGRQALSLNLI
DALGTTEDALTWLQQEKKLSLDLRVIELHTQTKLDSYIELFQNNIRKLFFGSKINGVMALYC

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=211, Percent_Identity=35.5450236966825, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787527, Length=170, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 33574; Mature: 33574

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIDPDYLIERKYYKSQLKKWKILTLLLITAIVVLFIFRNRVGYSPSLATGDYIANIQID
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEC
DLIYDDIKLNNLLHQIKNDDKAKALILHVDSPGGTVAGSEKIYGILRSISNSKPVVAVLG
CEEECHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE
TVAASGGYLVALAADYIIAQKSTVTGSIGIVHFSPEITEFGEKIGIKFHTFKSGELKAAP
HHHCCCCEEEEEEHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHCCEEEEECCCCCCCCC
SLTEKVTPAVHEATMTLINDMYDFFVELVAERRQMSPEQVLKVADGKAYTGRQALSLNLI
CHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEEHH
DALGTTEDALTWLQQEKKLSLDLRVIELHTQTKLDSYIELFQNNIRKLFFGSKINGVMAL
HHCCCCHHHHHHHHHHCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
YC
EC
>Mature Secondary Structure
MIIDPDYLIERKYYKSQLKKWKILTLLLITAIVVLFIFRNRVGYSPSLATGDYIANIQID
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEC
DLIYDDIKLNNLLHQIKNDDKAKALILHVDSPGGTVAGSEKIYGILRSISNSKPVVAVLG
CEEECHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEE
TVAASGGYLVALAADYIIAQKSTVTGSIGIVHFSPEITEFGEKIGIKFHTFKSGELKAAP
HHHCCCCEEEEEEHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHCCEEEEECCCCCCCCC
SLTEKVTPAVHEATMTLINDMYDFFVELVAERRQMSPEQVLKVADGKAYTGRQALSLNLI
CHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEEHH
DALGTTEDALTWLQQEKKLSLDLRVIELHTQTKLDSYIELFQNNIRKLFFGSKINGVMAL
HHCCCCHHHHHHHHHHCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
YC
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]