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The map label for this gene is gap [H]

Identifier: 189182910

GI number: 189182910

Start: 7705

End: 8721

Strand: Direct

Name: gap [H]

Synonym: OTT_0003

Alternate gene names: 189182910

Gene position: 7705-8721 (Clockwise)

Preceding gene: NA

Following gene: 189182911

Centisome position: 0.38

GC content: 32.25

Gene sequence:

>1017_bases
ATGAGAATTGCTGTTAACGGTCTTGGACGTATTGGAAGATTAGTAGTTAGGGCAATCACTTTGCTACAGGATAGCAGACT
TGAATTAGTGGCTGCAAATAGCCTTGCAGAGTCAGATATCATTGCTCATCTTTTGAATTATGACTCAACTCATGGCAAAT
TAACAAACAGATTTCAATATAATAATAATTATCTATTTAATAGTACAAGCAAGATTAGCCTCTTTAGGCAAAGTAAACCA
GAAACTATTCCATGGGAAAAAGAGAACATTGATATAGTTATAGAATGTTCCGGCAAATTTAATAGTAAAAATGCTGCCAC
AGCTCATTTAACAGCTGGAGCAAAAAAAGTAATTATCTCTGCCCCATGTGAAAATGCTGACGCTACAATTATAGTTGGAG
TTAATGATCATTTACTCAATTCAAATCATAACATTATATCAGTTGGATCCTGCACTACTAATGCAGTTGCTCCTATAGTT
AAAATTTTAAATGATAAATTTGGCATTCAATGTGGTCATATTACTACTGTTCATGCTTATACTAGCGATCAAAATATTTT
GGATAATAGTCATAAAGATTTTAGACGAGCAAGATCATGTTTTACATCAATAATACCAACTAAGACAGGTGTTTCAACAT
CTTTGAAAGAGGTAATACCAGAATTAGCTAACTGTTTAGATGGCTCCTCAGTTAGAGTTCCAACATCTAATGTGTCACTA
ATTGATTTTACTTTTTATAGTCATAAAACTCTTACTGTTCAATCTATCAATAATGAAATTAAAGAATCAGCTAAATTAGC
TAATATGAAGGATATTCTTGATATTGCGCCAGCTCCACTAGTTTCAGTAGATTTTAATCATTCAAAATTTAGTGCTATAT
TTGATCCATATGAAACTAAGGTAGTAGGTAAAAATCTTGGTAGAATAGTAGCATGGTATGATAATGAGTGGGGGTTTGTG
CATCGTATAATAGACATAGTTAAAACAGTTGAATTATGTTGCAGAGATGAGAAATGA

Upstream 100 bases:

>100_bases
ATCAATAAATATAACTTTAAGTAATTGTTTATCAGACACTAAATAATTATATTATAGTTTTTAGTGTAAAATTATTACTT
ATAAAAAGCAGAAGAAATTT

Downstream 100 bases:

>100_bases
AAGAAATAATATTACACTACTAGCACAGTAATTCAACTTCCTTGACTATATATGTAAACTGACACAAGTATGAAATATTT
ATGATACAGTTAAGACAACT

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRIAVNGLGRIGRLVVRAITLLQDSRLELVAANSLAESDIIAHLLNYDSTHGKLTNRFQYNNNYLFNSTSKISLFRQSKP
ETIPWEKENIDIVIECSGKFNSKNAATAHLTAGAKKVIISAPCENADATIIVGVNDHLLNSNHNIISVGSCTTNAVAPIV
KILNDKFGIQCGHITTVHAYTSDQNILDNSHKDFRRARSCFTSIIPTKTGVSTSLKEVIPELANCLDGSSVRVPTSNVSL
IDFTFYSHKTLTVQSINNEIKESAKLANMKDILDIAPAPLVSVDFNHSKFSAIFDPYETKVVGKNLGRIVAWYDNEWGFV
HRIIDIVKTVELCCRDEK

Sequences:

>Translated_338_residues
MRIAVNGLGRIGRLVVRAITLLQDSRLELVAANSLAESDIIAHLLNYDSTHGKLTNRFQYNNNYLFNSTSKISLFRQSKP
ETIPWEKENIDIVIECSGKFNSKNAATAHLTAGAKKVIISAPCENADATIIVGVNDHLLNSNHNIISVGSCTTNAVAPIV
KILNDKFGIQCGHITTVHAYTSDQNILDNSHKDFRRARSCFTSIIPTKTGVSTSLKEVIPELANCLDGSSVRVPTSNVSL
IDFTFYSHKTLTVQSINNEIKESAKLANMKDILDIAPAPLVSVDFNHSKFSAIFDPYETKVVGKNLGRIVAWYDNEWGFV
HRIIDIVKTVELCCRDEK
>Mature_338_residues
MRIAVNGLGRIGRLVVRAITLLQDSRLELVAANSLAESDIIAHLLNYDSTHGKLTNRFQYNNNYLFNSTSKISLFRQSKP
ETIPWEKENIDIVIECSGKFNSKNAATAHLTAGAKKVIISAPCENADATIIVGVNDHLLNSNHNIISVGSCTTNAVAPIV
KILNDKFGIQCGHITTVHAYTSDQNILDNSHKDFRRARSCFTSIIPTKTGVSTSLKEVIPELANCLDGSSVRVPTSNVSL
IDFTFYSHKTLTVQSINNEIKESAKLANMKDILDIAPAPLVSVDFNHSKFSAIFDPYETKVVGKNLGRIVAWYDNEWGFV
HRIIDIVKTVELCCRDEK

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=36.2537764350453, Blast_Score=228, Evalue=7e-60,
Organism=Homo sapiens, GI7669492, Length=329, Percent_Identity=36.7781155015198, Blast_Score=223, Evalue=3e-58,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=39.209726443769, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=36.890243902439, Blast_Score=239, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17534679, Length=333, Percent_Identity=39.6396396396396, Blast_Score=231, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=39.3393393393393, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=38.9380530973451, Blast_Score=222, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17568413, Length=336, Percent_Identity=38.6904761904762, Blast_Score=221, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6322468, Length=332, Percent_Identity=38.855421686747, Blast_Score=246, Evalue=5e-66,
Organism=Saccharomyces cerevisiae, GI6321631, Length=332, Percent_Identity=37.9518072289157, Blast_Score=243, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6322409, Length=332, Percent_Identity=37.3493975903614, Blast_Score=240, Evalue=2e-64,
Organism=Drosophila melanogaster, GI19922412, Length=332, Percent_Identity=39.4578313253012, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI85725000, Length=333, Percent_Identity=37.2372372372372, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI22023983, Length=333, Percent_Identity=37.2372372372372, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI17933600, Length=333, Percent_Identity=36.6366366366366, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI18110149, Length=333, Percent_Identity=36.6366366366366, Blast_Score=216, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37344; Mature: 37344

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAVNGLGRIGRLVVRAITLLQDSRLELVAANSLAESDIIAHLLNYDSTHGKLTNRFQY
CEEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEEEEE
NNNYLFNSTSKISLFRQSKPETIPWEKENIDIVIECSGKFNSKNAATAHLTAGAKKVIIS
CCCEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCEEEEEE
APCENADATIIVGVNDHLLNSNHNIISVGSCTTNAVAPIVKILNDKFGIQCGHITTVHAY
CCCCCCCEEEEEECCHHEECCCCCEEEECCCCCHHHHHHHHHHHHHCCEEECCEEEEEEE
TSDQNILDNSHKDFRRARSCFTSIIPTKTGVSTSLKEVIPELANCLDGSSVRVPTSNVSL
CCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEE
IDFTFYSHKTLTVQSINNEIKESAKLANMKDILDIAPAPLVSVDFNHSKFSAIFDPYETK
EEEEEECCCEEEHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCCHHHHHCCCHHHE
VVGKNLGRIVAWYDNEWGFVHRIIDIVKTVELCCRDEK
ECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRIAVNGLGRIGRLVVRAITLLQDSRLELVAANSLAESDIIAHLLNYDSTHGKLTNRFQY
CEEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEEEEE
NNNYLFNSTSKISLFRQSKPETIPWEKENIDIVIECSGKFNSKNAATAHLTAGAKKVIIS
CCCEEECCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCEEEEEE
APCENADATIIVGVNDHLLNSNHNIISVGSCTTNAVAPIVKILNDKFGIQCGHITTVHAY
CCCCCCCEEEEEECCHHEECCCCCEEEECCCCCHHHHHHHHHHHHHCCEEECCEEEEEEE
TSDQNILDNSHKDFRRARSCFTSIIPTKTGVSTSLKEVIPELANCLDGSSVRVPTSNVSL
CCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCEE
IDFTFYSHKTLTVQSINNEIKESAKLANMKDILDIAPAPLVSVDFNHSKFSAIFDPYETK
EEEEEECCCEEEHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCCHHHHHCCCHHHE
VVGKNLGRIVAWYDNEWGFVHRIIDIVKTVELCCRDEK
ECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8508805; 10360571; 2401296; 7877172 [H]