Click here to switch to the map view.

The map label for this gene is ygbD [C]

Identifier: 189026144

GI number: 189026144

Start: 1000695

End: 1002032

Strand: Direct

Name: ygbD [C]

Synonym: TPASS_0921

Alternate gene names: 189026144

Gene position: 1000695-1002032 (Clockwise)

Preceding gene: 189026143

Following gene: 189026147

Centisome position: 87.82

GC content: 49.4

Gene sequence:

>1338_bases
GTGAAGATCGTCATTATCGGAGCGAACCACGCAGGAACCGCCTGTGTCAATTGCCTCACAGACCTTACCACCACGAATGA
AGTGGTAGTCTTTGACCGTAACAATAATATTAGCTTCCTTGGTTGCGGCATGGCTCTTTGGATTGGCGGACAAATCCGTG
GATCGGAGGGTCTATTCTACGCAAATAAAGAACAATTGGAAAAAAAGGGTGCACGCGTTTCCATGGAAAGCGATATCACC
CGTATCGATTTTGCCTCAAAAAAGGTGTACGGGACTGCACGAGACGGTTCTGCAATCGCAGAGTCCTACGACAAGCTTAT
TATTGCAACCGGTTCTCTGCCTATCATTCCTAAAATCGACGGCATGGATTTGGAGAATGTTCAGCGCATTAAGCTATTTC
AGGATGCTGAAGCGGTGATTAAAAAACTCGAGCAGCCTTCCATTAAGAATATTGCCGTTATCGGTGCCGGGTACATTGGC
GTGGAGCTTGCAGAGGCGTTTGAGCGCCACCAAAAAAAGGTAACGCTCATCGATGCGATGGACTCTAGTCTTTCCAATTA
TTACGACGCATCCTTCCGTGCACTCATGGATGAGAACTTGCGCAGCCATCACATCACCCTTGCGTTTGGCCAGAAAGTGC
AAAAACTCCGTGGCAGCAATGGAAAGGTAGTGGCAGTGGTGACAGATAAGGGTGAGTACCCCGCAGACATGGTTATGGTG
TGCATTGGCTTTAGCCCCAATACTGCACTGGGAAAGAACGAGGTGCGAACCTTTGCCAATGGCGCGTATGCGGTAGATTT
AAAACAAGAAACAAGTGTGAAAGACGTGTACGCAATTGGCGATTGTGCAACGGTGTTTGACAATTCGCTCGGACAAACTT
CTTACATTGCGCTTGCAACCAATGCGATGCGCAGCGGTATCGTTGCGGCGCACAACGCTGCAGGATTCCCACTTGAAGGC
ATTGGGGTGCAGGGCTCCAACGGTATCAACATATACGACTTAAAAATGGTGTCCACAGGAGTGACGCAGGAGCGCGCCGC
GCGCATGGGACTTGAGGTGGAGGTAACGGATTTTGAAGACTCACAGTTACCCGCCTTTATGGAAGTGGACAATCACCCGG
TGAAAATCCGGATTGTGTTTGATAAAAAAACGCGGGTGATTGTGGGCGCTCAAATGGCGTCACGGCACGACATGTCGATG
GGTATTCACCTGTTCTCTCTTGCAATCCAGGAGCGGGTGACCATTGATAAGTTAAAACTGCTGGACATGTTCTTTCTGCC
GCATTTTAACAAGCCGTACAACTACGTTACGATGGCGGCCTTGCGTGCGCGCTCATAA

Upstream 100 bases:

>100_bases
CCAGTTATCGCGTTTGGGAACAAAACAACCGCGGCTGTTTTCAGGCGCCTGTACAAAAATCTTTTCCCTGAACTACAATG
CCAAACGTAAGGAGGACGCC

Downstream 100 bases:

>100_bases
GTGCACCGTGCGTCTCTTACGCTTTCCCGGGGATGGCGCCGGGGGCGTGCTCCGTTTTGCTAGAAGACTTCTATGAGCGA
AACGCTCACGCTAGTTATTC

Product: NADH oxidase

Products: NA

Alternate protein names: NOXase [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKIVIIGANHAGTACVNCLTDLTTTNEVVVFDRNNNISFLGCGMALWIGGQIRGSEGLFYANKEQLEKKGARVSMESDIT
RIDFASKKVYGTARDGSAIAESYDKLIIATGSLPIIPKIDGMDLENVQRIKLFQDAEAVIKKLEQPSIKNIAVIGAGYIG
VELAEAFERHQKKVTLIDAMDSSLSNYYDASFRALMDENLRSHHITLAFGQKVQKLRGSNGKVVAVVTDKGEYPADMVMV
CIGFSPNTALGKNEVRTFANGAYAVDLKQETSVKDVYAIGDCATVFDNSLGQTSYIALATNAMRSGIVAAHNAAGFPLEG
IGVQGSNGINIYDLKMVSTGVTQERAARMGLEVEVTDFEDSQLPAFMEVDNHPVKIRIVFDKKTRVIVGAQMASRHDMSM
GIHLFSLAIQERVTIDKLKLLDMFFLPHFNKPYNYVTMAALRARS

Sequences:

>Translated_445_residues
MKIVIIGANHAGTACVNCLTDLTTTNEVVVFDRNNNISFLGCGMALWIGGQIRGSEGLFYANKEQLEKKGARVSMESDIT
RIDFASKKVYGTARDGSAIAESYDKLIIATGSLPIIPKIDGMDLENVQRIKLFQDAEAVIKKLEQPSIKNIAVIGAGYIG
VELAEAFERHQKKVTLIDAMDSSLSNYYDASFRALMDENLRSHHITLAFGQKVQKLRGSNGKVVAVVTDKGEYPADMVMV
CIGFSPNTALGKNEVRTFANGAYAVDLKQETSVKDVYAIGDCATVFDNSLGQTSYIALATNAMRSGIVAAHNAAGFPLEG
IGVQGSNGINIYDLKMVSTGVTQERAARMGLEVEVTDFEDSQLPAFMEVDNHPVKIRIVFDKKTRVIVGAQMASRHDMSM
GIHLFSLAIQERVTIDKLKLLDMFFLPHFNKPYNYVTMAALRARS
>Mature_445_residues
MKIVIIGANHAGTACVNCLTDLTTTNEVVVFDRNNNISFLGCGMALWIGGQIRGSEGLFYANKEQLEKKGARVSMESDIT
RIDFASKKVYGTARDGSAIAESYDKLIIATGSLPIIPKIDGMDLENVQRIKLFQDAEAVIKKLEQPSIKNIAVIGAGYIG
VELAEAFERHQKKVTLIDAMDSSLSNYYDASFRALMDENLRSHHITLAFGQKVQKLRGSNGKVVAVVTDKGEYPADMVMV
CIGFSPNTALGKNEVRTFANGAYAVDLKQETSVKDVYAIGDCATVFDNSLGQTSYIALATNAMRSGIVAAHNAAGFPLEG
IGVQGSNGINIYDLKMVSTGVTQERAARMGLEVEVTDFEDSQLPAFMEVDNHPVKIRIVFDKKTRVIVGAQMASRHDMSM
GIHLFSLAIQERVTIDKLKLLDMFFLPHFNKPYNYVTMAALRARS

Specific function: Catalyzes the four-electron reduction of molecular oxygen to water [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=285, Percent_Identity=26.3157894736842, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI226437568, Length=285, Percent_Identity=26.3157894736842, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI65787454, Length=285, Percent_Identity=26.3157894736842, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1789065, Length=206, Percent_Identity=29.6116504854369, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87082354, Length=398, Percent_Identity=22.3618090452261, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24639257, Length=264, Percent_Identity=26.1363636363636, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281359715, Length=264, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281359713, Length=264, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639250, Length=264, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18543267, Length=264, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639252, Length=264, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585130, Length=191, Percent_Identity=27.2251308900524, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 48645; Mature: 48645

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVIIGANHAGTACVNCLTDLTTTNEVVVFDRNNNISFLGCGMALWIGGQIRGSEGLFY
CEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEEECCEEEEECCEEECCCCEEE
ANKEQLEKKGARVSMESDITRIDFASKKVYGTARDGSAIAESYDKLIIATGSLPIIPKID
ECHHHHHHCCCEEEECCCCEEEEECCCEEEEECCCCHHHHHCCCEEEEEECCCCCEECCC
GMDLENVQRIKLFQDAEAVIKKLEQPSIKNIAVIGAGYIGVELAEAFERHQKKVTLIDAM
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHCCEEEEEEHH
DSSLSNYYDASFRALMDENLRSHHITLAFGQKVQKLRGSNGKVVAVVTDKGEYPADMVMV
HHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEE
CIGFSPNTALGKNEVRTFANGAYAVDLKQETSVKDVYAIGDCATVFDNSLGQTSYIALAT
EEECCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCEEEECCHHHHHCCCCCCCEEEEEEH
NAMRSGIVAAHNAAGFPLEGIGVQGSNGINIYDLKMVSTGVTQERAARMGLEVEVTDFED
HHHHCCEEEECCCCCCCEECCCCCCCCCCEEEEEEEEECCCCHHHHHHCCCEEEEECCCC
SQLPAFMEVDNHPVKIRIVFDKKTRVIVGAQMASRHDMSMGIHLFSLAIQERVTIDKLKL
CCCCEEEEECCCCEEEEEEECCCCEEEEEEHHHCCCCCHHHHHHHHHHHHHCCCHHHHHH
LDMFFLPHFNKPYNYVTMAALRARS
HHHHHCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MKIVIIGANHAGTACVNCLTDLTTTNEVVVFDRNNNISFLGCGMALWIGGQIRGSEGLFY
CEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEEECCEEEEECCEEECCCCEEE
ANKEQLEKKGARVSMESDITRIDFASKKVYGTARDGSAIAESYDKLIIATGSLPIIPKID
ECHHHHHHCCCEEEECCCCEEEEECCCEEEEECCCCHHHHHCCCEEEEEECCCCCEECCC
GMDLENVQRIKLFQDAEAVIKKLEQPSIKNIAVIGAGYIGVELAEAFERHQKKVTLIDAM
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHCCEEEEEEHH
DSSLSNYYDASFRALMDENLRSHHITLAFGQKVQKLRGSNGKVVAVVTDKGEYPADMVMV
HHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEE
CIGFSPNTALGKNEVRTFANGAYAVDLKQETSVKDVYAIGDCATVFDNSLGQTSYIALAT
EEECCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCEEEECCHHHHHCCCCCCCEEEEEEH
NAMRSGIVAAHNAAGFPLEGIGVQGSNGINIYDLKMVSTGVTQERAARMGLEVEVTDFED
HHHHCCEEEECCCCCCCEECCCCCCCCCCEEEEEEEEECCCCHHHHHHCCCEEEEECCCC
SQLPAFMEVDNHPVKIRIVFDKKTRVIVGAQMASRHDMSMGIHLFSLAIQERVTIDKLKL
CCCCEEEEECCCCEEEEEEECCCCEEEEEEHHHCCCCCHHHHHHHHHHHHHCCCHHHHHH
LDMFFLPHFNKPYNYVTMAALRARS
HHHHHCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA