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The map label for this gene is acpS

Identifier: 189026052

GI number: 189026052

Start: 896820

End: 897197

Strand: Direct

Name: acpS

Synonym: TPASS_0828

Alternate gene names: 189026052

Gene position: 896820-897197 (Clockwise)

Preceding gene: 189026051

Following gene: 189026053

Centisome position: 78.71

GC content: 49.21

Gene sequence:

>378_bases
ATGATCATTGGCGTGGGAATAGACATAGTAGAAATAGAACGATTCGTATCTTGGACACACAACGTGCGCCTGCTCCGTCG
CTTCTTTCATCAAGAGGAGATTGTAGACTTTTTTAAAAACCACATGCGAGCGCAGTTTCTTGCCACGCGCTTTGCCGCAA
AGGAAGCATTTGGAAAGGCACTCGGTACGGGACTCAGAAACATGGAGCTAAGGAATATTCGGGTGTGTCAAAATGGATGG
GGTAAGCCGAGACTAGAAGTCTACGGTGCTGCACAGGCTATGTTGGCTGCAACAGGAGGCACGCATATACAGGTGTCGCT
AACGCATGAGAGAGAAGTCGCCTCAGCCATCGTGATTATCGAGGGAGAACCGCTATGA

Upstream 100 bases:

>100_bases
TCCTCTCGCTGCCCGAACACGTGCGTATGGTACAGTACAGTCCCAAAGAGGTTCACGTTCATGTGCGCGAAGCGCAGTCA
GTCCCGGCGGACGGACATGA

Downstream 100 bases:

>100_bases
CCCGGTCATCTACAAAGAAAACAGACAAAAAAGAAAGCACTGTGTCTTTCTATTCAAAAGAGCGCATCGAGTGTCCGGTG
TGCACAACCGTCTTCCAAAG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MIIGVGIDIVEIERFVSWTHNVRLLRRFFHQEEIVDFFKNHMRAQFLATRFAAKEAFGKALGTGLRNMELRNIRVCQNGW
GKPRLEVYGAAQAMLAATGGTHIQVSLTHEREVASAIVIIEGEPL

Sequences:

>Translated_125_residues
MIIGVGIDIVEIERFVSWTHNVRLLRRFFHQEEIVDFFKNHMRAQFLATRFAAKEAFGKALGTGLRNMELRNIRVCQNGW
GKPRLEVYGAAQAMLAATGGTHIQVSLTHEREVASAIVIIEGEPL
>Mature_125_residues
MIIGVGIDIVEIERFVSWTHNVRLLRRFFHQEEIVDFFKNHMRAQFLATRFAAKEAFGKALGTGLRNMELRNIRVCQNGW
GKPRLEVYGAAQAMLAATGGTHIQVSLTHEREVASAIVIIEGEPL

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=124, Percent_Identity=41.1290322580645, Blast_Score=79, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_TREPA (O83800)

Other databases:

- EMBL:   AE000520
- PIR:   F71276
- RefSeq:   NP_219264.1
- ProteinModelPortal:   O83800
- SMR:   O83800
- GeneID:   2610945
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0828
- NMPDR:   fig|243276.1.peg.823
- TIGR:   TP_0828
- HOGENOM:   HBG734479
- OMA:   DYAIAFI
- ProtClustDB:   PRK00070
- BioCyc:   TPAL243276:TP_0828-MONOMER
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14119; Mature: 14119

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGVGIDIVEIERFVSWTHNVRLLRRFFHQEEIVDFFKNHMRAQFLATRFAAKEAFGKA
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGTGLRNMELRNIRVCQNGWGKPRLEVYGAAQAMLAATGGTHIQVSLTHEREVASAIVII
HHCCCCCCEECEEEEECCCCCCCCEEEHHHHHHHHEECCCCEEEEEECCCCCCEEEEEEE
EGEPL
ECCCC
>Mature Secondary Structure
MIIGVGIDIVEIERFVSWTHNVRLLRRFFHQEEIVDFFKNHMRAQFLATRFAAKEAFGKA
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGTGLRNMELRNIRVCQNGWGKPRLEVYGAAQAMLAATGGTHIQVSLTHEREVASAIVII
HHCCCCCCEECEEEEECCCCCCCCEEEHHHHHHHHEECCCCEEEEEECCCCCCEEEEEEE
EGEPL
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876