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The map label for this gene is dacC [H]

Identifier: 189026025

GI number: 189026025

Start: 868279

End: 869751

Strand: Direct

Name: dacC [H]

Synonym: TPASS_0800

Alternate gene names: 189026025

Gene position: 868279-869751 (Clockwise)

Preceding gene: 189026024

Following gene: 189026027

Centisome position: 76.2

GC content: 57.88

Gene sequence:

>1473_bases
GTGCCGGGACACCCGGTACACGCGTGTACTGCCCGTTTGAAAGACCACTCATCGCGCTCCCTGCGCGCCGTGGCACGGCG
GCGTGGGCAGCGCGCGCTGTATGCGTTAGGTGCGTGCGTAGTCGGGGCAGGGGCGCTGCAGTGGCACGCGCAGCGAGTAC
TCCACCCTTCCTTTCTTTTCTCCCCAACACTGCGTTTTTCTCCGTCGTCCCGTAATCCCTTTTCTGCTCACCCTATCCGT
ACGCTTCAATTTACCAATCTATCTGCAGGATCCACMCCACCCCCCATCAGTGCCCGCGCGTACGCCATCGCCGAAGGAGG
AAGCGGCACACTCCTTGCCTCCTTCTGCGCAGACCTACCCCTCCCCCCGGCGTCCTTGGCAAAACTGGTTACCTGTGCAG
TGGTCATGGAAGCACTCGAGCGTGGAGAACTCCACTGGCAACAGCGTATACGCGTACCGCTTGCAGGTAGCGCGCAGGCC
TTTGCACCGGGCAGCTCGCTTATATTTTTACGTACAGGTGAGTACATCAGCGTACACGACTTACTCGCAGGTATGAACAT
CGCTTCGGGGAACGATGCAGCCTACACCCTCGCTTATGCAGTTGCAGGCAGTATACCGGCGTTCTGCACGCGCATGAACA
CGCTTGTACAGAAATGGGGTCTTACGCGCACACGCTTTGTGGAACCAAGCGGTCTGAGCGAACACAATGTAACTACTGCG
CGTGACTTTGTGCTCTTTTGTTGCCAGTATGTGCGCCGATGGCCTGAAAACCTTGCACGCTTTCATGCGCGCAGCTACTT
TCAGCGTAGTAACTCTCCCGCTACTTCGAGAATACCCCCACACACACGTTTCCCTGCAACCAACACCCTGCTTGCAGCAA
CCGCAGCGCGCGGAAACGTTTCCACAGCAGTGCCCGGCTGCGACGGATTAAAAACTGGCTATATCCGCGAATCCGGTTTT
AACGTCGCGCTCAGCAGTCTGCGCGGAGACACCCGCATCATTGCAGTTATCTTAGGCGGCGCAGGGAATTCCATTCCCGA
AGGAAAGCGCATCCGCGCGCGTGACGGCGCTACCCTTCTATACTGGGCGTTCACCCATTTCCAGTGCACCGATGTACGCA
CGGCTATCAGTGATGCGCTTCCCTGTGCTATTCCCGTCCTGGGCAGTAAGCGCCCTGGGGCACTGCGACCAATCCTCCAC
CCCTCGTGTACATCGTGCCCAGTTCTGAATACGCCCGGTACGCGCATCAGCATAACGTTCGCACTCCCTCCCCTTTTGCG
CGCACCGCTACAAGAAACGGACGTTATCGGTTTTGCGCATGTTCTTGACGAATCAAATGGAATGGTGCTCGCTCGCGTTC
CGCTCGTTTCAGGCACCACTCTCACTGCCGGTGGGAACGCACGCAGGATCATAGACGAGGTGGCGGTATGGAGTGTAGAG
CTTTGGCGGAAGATAAGAGAGAAACGCGTTTGA

Upstream 100 bases:

>100_bases
GTGGTGTTTTCTGTGATACACAGGACGTGTCGCGGCGTGCTTTTCAAGGGGTGACGCATGTGCGGTCGGCCCGTGCCGTA
CGCTCTGTCCCTAATACGGT

Downstream 100 bases:

>100_bases
ATAACTCAGTGCACGTGCACTGCCTACCACACGGATACACCGTTACCGTGCCACGCATCATCACCCCAGCGCGTCTTGGA
TACTCCCCGAATACGAAGAC

Product: serine-type D-Ala-D-Ala carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 5; PBP-5 [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MPGHPVHACTARLKDHSSRSLRAVARRRGQRALYALGACVVGAGALQWHAQRVLHPSFLFSPTLRFSPSSRNPFSAHPIR
TLQFTNLSAGSTPPPISARAYAIAEGGSGTLLASFCADLPLPPASLAKLVTCAVVMEALERGELHWQQRIRVPLAGSAQA
FAPGSSLIFLRTGEYISVHDLLAGMNIASGNDAAYTLAYAVAGSIPAFCTRMNTLVQKWGLTRTRFVEPSGLSEHNVTTA
RDFVLFCCQYVRRWPENLARFHARSYFQRSNSPATSRIPPHTRFPATNTLLAATAARGNVSTAVPGCDGLKTGYIRESGF
NVALSSLRGDTRIIAVILGGAGNSIPEGKRIRARDGATLLYWAFTHFQCTDVRTAISDALPCAIPVLGSKRPGALRPILH
PSCTSCPVLNTPGTRISITFALPPLLRAPLQETDVIGFAHVLDESNGMVLARVPLVSGTTLTAGGNARRIIDEVAVWSVE
LWRKIREKRV

Sequences:

>Translated_490_residues
MPGHPVHACTARLKDHSSRSLRAVARRRGQRALYALGACVVGAGALQWHAQRVLHPSFLFSPTLRFSPSSRNPFSAHPIR
TLQFTNLSAGSTPPPISARAYAIAEGGSGTLLASFCADLPLPPASLAKLVTCAVVMEALERGELHWQQRIRVPLAGSAQA
FAPGSSLIFLRTGEYISVHDLLAGMNIASGNDAAYTLAYAVAGSIPAFCTRMNTLVQKWGLTRTRFVEPSGLSEHNVTTA
RDFVLFCCQYVRRWPENLARFHARSYFQRSNSPATSRIPPHTRFPATNTLLAATAARGNVSTAVPGCDGLKTGYIRESGF
NVALSSLRGDTRIIAVILGGAGNSIPEGKRIRARDGATLLYWAFTHFQCTDVRTAISDALPCAIPVLGSKRPGALRPILH
PSCTSCPVLNTPGTRISITFALPPLLRAPLQETDVIGFAHVLDESNGMVLARVPLVSGTTLTAGGNARRIIDEVAVWSVE
LWRKIREKRV
>Mature_489_residues
PGHPVHACTARLKDHSSRSLRAVARRRGQRALYALGACVVGAGALQWHAQRVLHPSFLFSPTLRFSPSSRNPFSAHPIRT
LQFTNLSAGSTPPPISARAYAIAEGGSGTLLASFCADLPLPPASLAKLVTCAVVMEALERGELHWQQRIRVPLAGSAQAF
APGSSLIFLRTGEYISVHDLLAGMNIASGNDAAYTLAYAVAGSIPAFCTRMNTLVQKWGLTRTRFVEPSGLSEHNVTTAR
DFVLFCCQYVRRWPENLARFHARSYFQRSNSPATSRIPPHTRFPATNTLLAATAARGNVSTAVPGCDGLKTGYIRESGFN
VALSSLRGDTRIIAVILGGAGNSIPEGKRIRARDGATLLYWAFTHFQCTDVRTAISDALPCAIPVLGSKRPGALRPILHP
SCTSCPVLNTPGTRISITFALPPLLRAPLQETDVIGFAHVLDESNGMVLARVPLVSGTTLTAGGNARRIIDEVAVWSVEL
WRKIREKRV

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=390, Percent_Identity=30.7692307692308, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786851, Length=390, Percent_Identity=26.4102564102564, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87082022, Length=285, Percent_Identity=28.7719298245614, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082054, Length=190, Percent_Identity=30.5263157894737, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 52810; Mature: 52679

Theoretical pI: Translated: 10.77; Mature: 10.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGHPVHACTARLKDHSSRSLRAVARRRGQRALYALGACVVGAGALQWHAQRVLHPSFLF
CCCCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHC
SPTLRFSPSSRNPFSAHPIRTLQFTNLSAGSTPPPISARAYAIAEGGSGTLLASFCADLP
CCCEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCC
LPPASLAKLVTCAVVMEALERGELHWQQRIRVPLAGSAQAFAPGSSLIFLRTGEYISVHD
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEHHH
LLAGMNIASGNDAAYTLAYAVAGSIPAFCTRMNTLVQKWGLTRTRFVEPSGLSEHNVTTA
HHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHH
RDFVLFCCQYVRRWPENLARFHARSYFQRSNSPATSRIPPHTRFPATNTLLAATAARGNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
STAVPGCDGLKTGYIRESGFNVALSSLRGDTRIIAVILGGAGNSIPEGKRIRARDGATLL
CCCCCCCCCCCCCCEECCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEEECCCCEEE
YWAFTHFQCTDVRTAISDALPCAIPVLGSKRPGALRPILHPSCTSCPVLNTPGTRISITF
EEEEEEEEEHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
ALPPLLRAPLQETDVIGFAHVLDESNGMVLARVPLVSGTTLTAGGNARRIIDEVAVWSVE
ECCHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECEECCCEEECCCCHHHHHHHHHHHHHH
LWRKIREKRV
HHHHHHHCCC
>Mature Secondary Structure 
PGHPVHACTARLKDHSSRSLRAVARRRGQRALYALGACVVGAGALQWHAQRVLHPSFLF
CCCCHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHC
SPTLRFSPSSRNPFSAHPIRTLQFTNLSAGSTPPPISARAYAIAEGGSGTLLASFCADLP
CCCEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCC
LPPASLAKLVTCAVVMEALERGELHWQQRIRVPLAGSAQAFAPGSSLIFLRTGEYISVHD
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEEHHH
LLAGMNIASGNDAAYTLAYAVAGSIPAFCTRMNTLVQKWGLTRTRFVEPSGLSEHNVTTA
HHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHH
RDFVLFCCQYVRRWPENLARFHARSYFQRSNSPATSRIPPHTRFPATNTLLAATAARGNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
STAVPGCDGLKTGYIRESGFNVALSSLRGDTRIIAVILGGAGNSIPEGKRIRARDGATLL
CCCCCCCCCCCCCCEECCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEEECCCCEEE
YWAFTHFQCTDVRTAISDALPCAIPVLGSKRPGALRPILHPSCTSCPVLNTPGTRISITF
EEEEEEEEEHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
ALPPLLRAPLQETDVIGFAHVLDESNGMVLARVPLVSGTTLTAGGNARRIIDEVAVWSVE
ECCHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECEECCCEEECCCCHHHHHHHHHHHHHH
LWRKIREKRV
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]