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The map label for this gene is flgE

Identifier: 189025952

GI number: 189025952

Start: 793394

End: 794785

Strand: Reverse

Name: flgE

Synonym: TPASS_0727

Alternate gene names: 189025952

Gene position: 794785-793394 (Counterclockwise)

Preceding gene: 189025953

Following gene: 189025951

Centisome position: 69.75

GC content: 50.65

Gene sequence:

>1392_bases
ATGATGCGGTCACTTTTTTCAGGTGTGTCTGGTATGCAGAATCATCAAACGCGCATGGATGTCATTGGGAACAACGTCGC
GAACGTTAACACTACCGGTTTTAAGCGTGGGCGTGTTAATTTTCAAGATCTTATTTCTCAGCAACTGAGTGCGGCTGCGC
GTCCGAATGAAGAAGTTGGAGGAGTGAATCCCAAGGAAGTGGGATTGGGCGTGCTGATTGCAAGCATCGATACTGTTCAC
ACGCAAGGTGCACTGCAAACGACGGGTATCAATACGGATGTGTCTATTCAGGGGAGTGGTTTTTTTGTGCTGAAAAGTGG
GGAAAAGACGTTTTTCACCCGCGCAGGTGCCTTTGGGGTTGATAATGCGGGCACTCTCGTGAACCCTGCGAATGGTATGC
GCGTTCAAGGTTGGATGGCGCAGGACGTGGCGGGGGAGCGTTTAATTAATTCCTCTGCACAGACGCAGGATCTCGTTATC
CCCATTGGGCAAAAGATAGATGCGCAGCAGACCAGCACTGTTCACTATGCCTGTAATTTAGACAAGCGTCTGCCTGAGCT
TGCTGCAGATGCGAACGAAGCGGACGTGCGTAAGTCCACGTGGACAACTGACTTTCAAGTGTATGATAGCTTCGGGCAGC
AGCATACGTTGCAGATTAACTTTTCGCGTGTGCCGGGGACGAACAATCAGTGGCAGGCCACTGTCGCAGTGGATCCGGGG
ACAGAGGTAGATACGCAAACGCGTGTAGGGGTGGGGACATCTGACGGTGCGGCAAACACCTTTATTGTAAATTTTGATAA
TTTTGGACACCTCGCTTCAGTGACTGACACTGCAGGGAACGTGACCGGTCCTACCGGACAGGTGCTCCTTGAAGCGTCGT
ACGATGTTGTCGGTGCGAATCCGGACGATGCAGGGCAGGTTACGCGCCACGCTTTCACGCTCAACTTGGGTGAAATTGGC
ACCGCGCGCAATACGATTACGCAGTTTGCTGAACGCAGTACTACCAAAGCCTACCGGCAGGACGGTTACGCGATGGGATA
TTTGGAAAATTTTAAAATAGATCAAAGCGGTGTCATCACTGGTGTGTATTCAAATGGGGTGAGCCAAGACATTGGCCAGC
TCGCACTTGCAGGATTTGCAAATCAAGGTGGTCTTGAGAAGGCAGGAGAGAACACCTACGTACAATCGAACAACTCAGGG
ATAGCGAACATTAGCACGTCGGGGGTGATGGGGAAGGGAAAGTTGATTGCAGGGACACTTGAGATGAGCAACGTAGATTT
AACCGATCAATTTACGGATATGATCATTACCCAAAAAGGGTTTCAGGCGGGCGCAAAGACGATTCAGACATCAGACACCA
TGTTGGATACGGTGTTGAGTTTGAAGCGCTGA

Upstream 100 bases:

>100_bases
AAGGTGATTGCAGATCCGAGTGCGTCGTAGCAGTTGTATGGTTTGTGAACAGAGAAAGAGAGATTAGGAAAATGAGTCAC
ATGAGGAGGACACAGAGCAT

Downstream 100 bases:

>100_bases
TGTGTCGACTGTGTGAAAATGTATCTTAAGCGGCAGGTGGCGTGATGGGGATGAGGGATGATTAAAGTGACGCGACTGAA
TGGAAATGAAAATTGGGTAA

Product: flagellar hook protein FlgE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MMRSLFSGVSGMQNHQTRMDVIGNNVANVNTTGFKRGRVNFQDLISQQLSAAARPNEEVGGVNPKEVGLGVLIASIDTVH
TQGALQTTGINTDVSIQGSGFFVLKSGEKTFFTRAGAFGVDNAGTLVNPANGMRVQGWMAQDVAGERLINSSAQTQDLVI
PIGQKIDAQQTSTVHYACNLDKRLPELAADANEADVRKSTWTTDFQVYDSFGQQHTLQINFSRVPGTNNQWQATVAVDPG
TEVDTQTRVGVGTSDGAANTFIVNFDNFGHLASVTDTAGNVTGPTGQVLLEASYDVVGANPDDAGQVTRHAFTLNLGEIG
TARNTITQFAERSTTKAYRQDGYAMGYLENFKIDQSGVITGVYSNGVSQDIGQLALAGFANQGGLEKAGENTYVQSNNSG
IANISTSGVMGKGKLIAGTLEMSNVDLTDQFTDMIITQKGFQAGAKTIQTSDTMLDTVLSLKR

Sequences:

>Translated_463_residues
MMRSLFSGVSGMQNHQTRMDVIGNNVANVNTTGFKRGRVNFQDLISQQLSAAARPNEEVGGVNPKEVGLGVLIASIDTVH
TQGALQTTGINTDVSIQGSGFFVLKSGEKTFFTRAGAFGVDNAGTLVNPANGMRVQGWMAQDVAGERLINSSAQTQDLVI
PIGQKIDAQQTSTVHYACNLDKRLPELAADANEADVRKSTWTTDFQVYDSFGQQHTLQINFSRVPGTNNQWQATVAVDPG
TEVDTQTRVGVGTSDGAANTFIVNFDNFGHLASVTDTAGNVTGPTGQVLLEASYDVVGANPDDAGQVTRHAFTLNLGEIG
TARNTITQFAERSTTKAYRQDGYAMGYLENFKIDQSGVITGVYSNGVSQDIGQLALAGFANQGGLEKAGENTYVQSNNSG
IANISTSGVMGKGKLIAGTLEMSNVDLTDQFTDMIITQKGFQAGAKTIQTSDTMLDTVLSLKR
>Mature_463_residues
MMRSLFSGVSGMQNHQTRMDVIGNNVANVNTTGFKRGRVNFQDLISQQLSAAARPNEEVGGVNPKEVGLGVLIASIDTVH
TQGALQTTGINTDVSIQGSGFFVLKSGEKTFFTRAGAFGVDNAGTLVNPANGMRVQGWMAQDVAGERLINSSAQTQDLVI
PIGQKIDAQQTSTVHYACNLDKRLPELAADANEADVRKSTWTTDFQVYDSFGQQHTLQINFSRVPGTNNQWQATVAVDPG
TEVDTQTRVGVGTSDGAANTFIVNFDNFGHLASVTDTAGNVTGPTGQVLLEASYDVVGANPDDAGQVTRHAFTLNLGEIG
TARNTITQFAERSTTKAYRQDGYAMGYLENFKIDQSGVITGVYSNGVSQDIGQLALAGFANQGGLEKAGENTYVQSNNSG
IANISTSGVMGKGKLIAGTLEMSNVDLTDQFTDMIITQKGFQAGAKTIQTSDTMLDTVLSLKR

Specific function: Unknown

COG id: COG1749

COG function: function code N; Flagellar hook protein FlgE

Gene ontology:

Cell location: Bacterial flagellum basal body

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flagella basal body rod proteins family

Homologues:

Organism=Escherichia coli, GI1787316, Length=462, Percent_Identity=31.1688311688312, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1787318, Length=138, Percent_Identity=40.5797101449275, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLGE_TREPA (O07884)

Other databases:

- EMBL:   U28219
- EMBL:   AE000520
- PIR:   C71292
- RefSeq:   NP_219164.1
- ProteinModelPortal:   O07884
- SMR:   O07884
- IntAct:   O07884
- MINT:   MINT-6480548
- GeneID:   2611034
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0727
- NMPDR:   fig|243276.1.peg.723
- TIGR:   TP_0727
- HOGENOM:   HBG579156
- OMA:   ANPNGLQ
- ProtClustDB:   PRK05682
- BioCyc:   TPAL243276:TP_0727-MONOMER
- InterPro:   IPR010930
- InterPro:   IPR011491
- InterPro:   IPR001444
- InterPro:   IPR019776
- InterPro:   IPR020013
- TIGRFAMs:   TIGR03506

Pfam domain/function: PF06429 DUF1078; PF07559 FlaE; PF00460 Flg_bb_rod

EC number: NA

Molecular weight: Translated: 49179; Mature: 49179

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00588 FLAGELLA_BB_ROD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRSLFSGVSGMQNHQTRMDVIGNNVANVNTTGFKRGRVNFQDLISQQLSAAARPNEEVG
CCHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCC
GVNPKEVGLGVLIASIDTVHTQGALQTTGINTDVSIQGSGFFVLKSGEKTFFTRAGAFGV
CCCHHHHCEEEEEEEHHHHCCCCCEEECCCCCEEEEECCCEEEEECCCEEEEEECCCCCC
DNAGTLVNPANGMRVQGWMAQDVAGERLINSSAQTQDLVIPIGQKIDAQQTSTVHYACNL
CCCCCEECCCCCCEEECEEHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEEEEECC
DKRLPELAADANEADVRKSTWTTDFQVYDSFGQQHTLQINFSRVPGTNNQWQATVAVDPG
HHHHHHHHCCCCHHHCCCCCCCCHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEEEECCC
TEVDTQTRVGVGTSDGAANTFIVNFDNFGHLASVTDTAGNVTGPTGQVLLEASYDVVGAN
CCCCCCEEECCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEECCEEEECC
PDDAGQVTRHAFTLNLGEIGTARNTITQFAERSTTKAYRQDGYAMGYLENFKIDQSGVIT
CCCCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEHCCCEECCCCEEE
GVYSNGVSQDIGQLALAGFANQGGLEKAGENTYVQSNNSGIANISTSGVMGKGKLIAGTL
EEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCEEEEEEE
EMSNVDLTDQFTDMIITQKGFQAGAKTIQTSDTMLDTVLSLKR
EECCCCCHHHHHHHHHHHCCHHHCCCEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MMRSLFSGVSGMQNHQTRMDVIGNNVANVNTTGFKRGRVNFQDLISQQLSAAARPNEEVG
CCHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHCC
GVNPKEVGLGVLIASIDTVHTQGALQTTGINTDVSIQGSGFFVLKSGEKTFFTRAGAFGV
CCCHHHHCEEEEEEEHHHHCCCCCEEECCCCCEEEEECCCEEEEECCCEEEEEECCCCCC
DNAGTLVNPANGMRVQGWMAQDVAGERLINSSAQTQDLVIPIGQKIDAQQTSTVHYACNL
CCCCCEECCCCCCEEECEEHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEEEEECC
DKRLPELAADANEADVRKSTWTTDFQVYDSFGQQHTLQINFSRVPGTNNQWQATVAVDPG
HHHHHHHHCCCCHHHCCCCCCCCHHHHHHCCCCCEEEEEEEEECCCCCCCEEEEEEECCC
TEVDTQTRVGVGTSDGAANTFIVNFDNFGHLASVTDTAGNVTGPTGQVLLEASYDVVGAN
CCCCCCEEECCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEECCEEEECC
PDDAGQVTRHAFTLNLGEIGTARNTITQFAERSTTKAYRQDGYAMGYLENFKIDQSGVIT
CCCCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEHCCCEECCCCEEE
GVYSNGVSQDIGQLALAGFANQGGLEKAGENTYVQSNNSGIANISTSGVMGKGKLIAGTL
EEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCEEEEEEE
EMSNVDLTDQFTDMIITQKGFQAGAKTIQTSDTMLDTVLSLKR
EECCCCCHHHHHHHHHHHCCHHHCCCEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755894; 9665876