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The map label for this gene is motA

Identifier: 189025950

GI number: 189025950

Start: 792344

End: 793123

Strand: Reverse

Name: motA

Synonym: TPASS_0725

Alternate gene names: 189025950

Gene position: 793123-792344 (Counterclockwise)

Preceding gene: 189025951

Following gene: 189025949

Centisome position: 69.61

GC content: 51.28

Gene sequence:

>780_bases
ATGGACATCGCATCGTTTATCGGGCTTTTCGGCGGTTTTGCCATCATTATCTTTGGTGCGGTGCTCGGTGGTTCTGCGAG
GGGGCTCTTTCACGTACCGTCATTGTTGATCACCGTGGGGGGCTCGTACTTAACGCTTTTTCTCACCTATCCGCTTTCGT
ATGCCGTGGGTGTTTTTCGGGTAATTGCGCGCGTTTTTCATGCGGCGGATTTTCACGAACGGGAGATTGTCCAGCGGCTC
TACGCGCTTGCTGAGAAAAGTCGGCGCACCGGTTTACTTGCGCTCGAAGAAGAAATTCAGGACTTTGACGATGACTTCGT
GCGCACTGGTTTGCGGAACGTGGTAGACGGTGTGGACGGAGATGCGATCAAGGCACTGATGGAAAGCGAGTTGACGCACA
TGGAGGATCGGCACAATACGTGGATTTCCCTTTTGAACTCCTGGGCTGCGCTCGCGCCCGGATATGGTATGCTGGGCACC
GTTATGGGGCTTATCGGTATGCTTGCAACGCTTGAAGACAAGTCCTCGCTGGGATCTAACATGGCAACTGCGCTTATCAC
TACTTTCTATGGTTCGCTGGTGCAAAATTGGTTCATTACTCCTGTCGCTACTAAGTTGCAGTATCAGCACGATTTGGAGG
TAAAGTCCAAGGAAATGGTAATAGAAGGGGTGCTTTCTATCCAGGCAGGGGATCATCCACGTGTTCTTGCGCAGCGATTG
CTGACGTACTTGAGTCCAAAGATGCGCAAGGAACTGGAAATGGAACTGATTAAGGATTAA

Upstream 100 bases:

>100_bases
TGTGGTGAGGGAAAGTGTGCAAGAAGTTATCGATAAAATTGTCTCCTATCGGCGCAGCATCGGCTGCCTCAACGACGAGA
CCTAAGACACGGGGGAAGCG

Downstream 100 bases:

>100_bases
TGCTCATGGCAAGGAAGAGGCGTGCTCCGCGCGGGGCGGCACAAGGGTGGCTAACGACATACTCAGATATGGTCACGCTT
ATGCTCTGTTTTTTTGTCAT

Product: flagellar motor rotation protein

Products: NA

Alternate protein names: Chemotaxis protein MotA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MDIASFIGLFGGFAIIIFGAVLGGSARGLFHVPSLLITVGGSYLTLFLTYPLSYAVGVFRVIARVFHAADFHEREIVQRL
YALAEKSRRTGLLALEEEIQDFDDDFVRTGLRNVVDGVDGDAIKALMESELTHMEDRHNTWISLLNSWAALAPGYGMLGT
VMGLIGMLATLEDKSSLGSNMATALITTFYGSLVQNWFITPVATKLQYQHDLEVKSKEMVIEGVLSIQAGDHPRVLAQRL
LTYLSPKMRKELEMELIKD

Sequences:

>Translated_259_residues
MDIASFIGLFGGFAIIIFGAVLGGSARGLFHVPSLLITVGGSYLTLFLTYPLSYAVGVFRVIARVFHAADFHEREIVQRL
YALAEKSRRTGLLALEEEIQDFDDDFVRTGLRNVVDGVDGDAIKALMESELTHMEDRHNTWISLLNSWAALAPGYGMLGT
VMGLIGMLATLEDKSSLGSNMATALITTFYGSLVQNWFITPVATKLQYQHDLEVKSKEMVIEGVLSIQAGDHPRVLAQRL
LTYLSPKMRKELEMELIKD
>Mature_259_residues
MDIASFIGLFGGFAIIIFGAVLGGSARGLFHVPSLLITVGGSYLTLFLTYPLSYAVGVFRVIARVFHAADFHEREIVQRL
YALAEKSRRTGLLALEEEIQDFDDDFVRTGLRNVVDGVDGDAIKALMESELTHMEDRHNTWISLLNSWAALAPGYGMLGT
VMGLIGMLATLEDKSSLGSNMATALITTFYGSLVQNWFITPVATKLQYQHDLEVKSKEMVIEGVLSIQAGDHPRVLAQRL
LTYLSPKMRKELEMELIKD

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi- pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family

Homologues:

Organism=Escherichia coli, GI1788199, Length=249, Percent_Identity=24.0963855421687, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): MOTA_TREPA (O07886)

Other databases:

- EMBL:   U28219
- EMBL:   AE000520
- PIR:   A71292
- RefSeq:   NP_219162.1
- ProteinModelPortal:   O07886
- IntAct:   O07886
- MINT:   MINT-6480176
- GeneID:   2611028
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0725
- NMPDR:   fig|243276.1.peg.721
- TIGR:   TP_0725
- HOGENOM:   HBG691813
- OMA:   ADKLHGK
- ProtClustDB:   CLSK218832
- BioCyc:   TPAL243276:TP_0725-MONOMER
- GO:   GO:0006935
- InterPro:   IPR000540
- InterPro:   IPR002898

Pfam domain/function: PF01618 MotA_ExbB

EC number: NA

Molecular weight: Translated: 28646; Mature: 28646

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x20f7d198)-; HASH(0x212393f8)-; HASH(0x20b42464)-; HASH(0x20bcaad0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCHHHHHHHHHHHHCH
>Mature Secondary Structure
MDIASFIGLFGGFAIIIFGAVLGGSARGLFHVPSLLITVGGSYLTLFLTYPLSYAVGVFR
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VIARVFHAADFHEREIVQRLYALAEKSRRTGLLALEEEIQDFDDDFVRTGLRNVVDGVDG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCH
DAIKALMESELTHMEDRHNTWISLLNSWAALAPGYGMLGTVMGLIGMLATLEDKSSLGSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MATALITTFYGSLVQNWFITPVATKLQYQHDLEVKSKEMVIEGVLSIQAGDHPRVLAQRL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LTYLSPKMRKELEMELIKD
HHHHCHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8755894; 9665876