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The map label for this gene is flhF

Identifier: 189025938

GI number: 189025938

Start: 781613

End: 782926

Strand: Reverse

Name: flhF

Synonym: TPASS_0713

Alternate gene names: 189025938

Gene position: 782926-781613 (Counterclockwise)

Preceding gene: 189025939

Following gene: 189025937

Centisome position: 68.71

GC content: 42.85

Gene sequence:

>1314_bases
GTGGAGTTATTAGTAGAAGTTGCCCCAACGAAGGAAAAAGCGATAGAGAAAATTCGGAAAAAGTATGGAGATCGAGTTAA
TATCCTGCGCACGCAGAGGAATAATAGGAGTTTCTTTTTTGGTCTCATAGAACGAGTCTCGGTAGAGATTTTTTTTTCTG
TCAATAGTGGATCGCAATCATCAGTACACGAGATACCCTCAGTGCAATCGCGTACGCGTGTGTCCGCTGCTCGGGTAGAG
GATACTGAAGCAGAAAAAATAAAGATACTTGAATCTGCGCAGCGTATTAATGCGAAGATAGCACAGCAGGTAGAGCCCTT
AATTTCAGCGGCAAAAGAGAAGAAAACTGAAAAAGTGCCAACTTCCCCTGAAGCGGTGCATGCGCTCACTCAAACGCTAG
AGGGTATGATCCAGAAGATCACGAATAGTGCGCCGGTGGTGATAGCACAGGAGTTGCAGTCGATTCAAAGAATCGAACTT
CTTTTAGAGGAAAATGATTTTAGTTTTTCATTTATAAGAAAAAGTATTGCTCGTCTAAAGGACGAACTCAGTTATCATGA
TTTAGAGTCTTTCGAAAAAGTTGAATCAACAGTCCTGCGATGGATTATAGAATCAGTCCACATTCAAGTTCCCCCTATTT
GTACCGGAACAAGAAACATTGTATTAGTAGGACCGACTGGTGTGGGAAAAACCACTACCCTCGCAAAGCTTGCCGCGTTC
TATTTTGTTACAGAACCGAAGCGAACTGGTATTCAGCCACGAGTAAAAATCATTACAACGGACAATTTTCGTATTGGTGC
AGCGTTTCAAATGGAACGTTATTGCGAGCTTATGGGACTCGATCTGTGTGTAGTGCAAGCACCGGTTGAGTTTTTGACGT
ACATGACACTGTATCAGCAGGAGACCGATGTGGTCTTTGTGGACACGGAAGGGAGGAGTCCGGTTGATGGACAGAATATA
GAGCGGATGGTGGAATACTTTCGTGCGGTAAAAAATTTTGAACTGGAAGTGTACCTTACCATTGACGCTGGATCGAAGGC
GAACGACTTGCGCGAGGTGTTTAAGCAATATGCGCTTTTTGAGTATCGTGCGCTGATAGTAACCAAACTTGATGAAACAA
CAAGTATTGGAAACCTCATTAGTGCGTTGAGTGAGGCAAGGACTCCTATCACCTATATTACGACAGGACAAACGGTTCCA
AGCAATTTAGAAAAGGCGTCAGTAAATTTACTACTTTCTAAATTAAAAGGTTTTAAACTTCTTGCTGAGGAGATGGGCAA
CGACTATGGTGATTACGGTAGCAAAGAGAGATAA

Upstream 100 bases:

>100_bases
ATTGAAACAGTGGGAGTAGTAAGGATAGAAGAGAGTGATGTGGATGCTTTTGTGAGAAAGCAGTAGTCTTCGGGCACAAG
ATGGGTGGAGGGTTTGATAG

Downstream 100 bases:

>100_bases
GCGCATAGCAGACCAGGCAGAAGAGCTGAGGGATTTGATGCAGGAAAAAAATGCGCGGGAGCGTGTTGAACGTCATCAGC
ATAGAACGCGTGTTGTCGTG

Product: flagellar-associated GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MELLVEVAPTKEKAIEKIRKKYGDRVNILRTQRNNRSFFFGLIERVSVEIFFSVNSGSQSSVHEIPSVQSRTRVSAARVE
DTEAEKIKILESAQRINAKIAQQVEPLISAAKEKKTEKVPTSPEAVHALTQTLEGMIQKITNSAPVVIAQELQSIQRIEL
LLEENDFSFSFIRKSIARLKDELSYHDLESFEKVESTVLRWIIESVHIQVPPICTGTRNIVLVGPTGVGKTTTLAKLAAF
YFVTEPKRTGIQPRVKIITTDNFRIGAAFQMERYCELMGLDLCVVQAPVEFLTYMTLYQQETDVVFVDTEGRSPVDGQNI
ERMVEYFRAVKNFELEVYLTIDAGSKANDLREVFKQYALFEYRALIVTKLDETTSIGNLISALSEARTPITYITTGQTVP
SNLEKASVNLLLSKLKGFKLLAEEMGNDYGDYGSKER

Sequences:

>Translated_437_residues
MELLVEVAPTKEKAIEKIRKKYGDRVNILRTQRNNRSFFFGLIERVSVEIFFSVNSGSQSSVHEIPSVQSRTRVSAARVE
DTEAEKIKILESAQRINAKIAQQVEPLISAAKEKKTEKVPTSPEAVHALTQTLEGMIQKITNSAPVVIAQELQSIQRIEL
LLEENDFSFSFIRKSIARLKDELSYHDLESFEKVESTVLRWIIESVHIQVPPICTGTRNIVLVGPTGVGKTTTLAKLAAF
YFVTEPKRTGIQPRVKIITTDNFRIGAAFQMERYCELMGLDLCVVQAPVEFLTYMTLYQQETDVVFVDTEGRSPVDGQNI
ERMVEYFRAVKNFELEVYLTIDAGSKANDLREVFKQYALFEYRALIVTKLDETTSIGNLISALSEARTPITYITTGQTVP
SNLEKASVNLLLSKLKGFKLLAEEMGNDYGDYGSKER
>Mature_437_residues
MELLVEVAPTKEKAIEKIRKKYGDRVNILRTQRNNRSFFFGLIERVSVEIFFSVNSGSQSSVHEIPSVQSRTRVSAARVE
DTEAEKIKILESAQRINAKIAQQVEPLISAAKEKKTEKVPTSPEAVHALTQTLEGMIQKITNSAPVVIAQELQSIQRIEL
LLEENDFSFSFIRKSIARLKDELSYHDLESFEKVESTVLRWIIESVHIQVPPICTGTRNIVLVGPTGVGKTTTLAKLAAF
YFVTEPKRTGIQPRVKIITTDNFRIGAAFQMERYCELMGLDLCVVQAPVEFLTYMTLYQQETDVVFVDTEGRSPVDGQNI
ERMVEYFRAVKNFELEVYLTIDAGSKANDLREVFKQYALFEYRALIVTKLDETTSIGNLISALSEARTPITYITTGQTVP
SNLEKASVNLLLSKLKGFKLLAEEMGNDYGDYGSKER

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family

Homologues:

Organism=Caenorhabditis elegans, GI17539958, Length=258, Percent_Identity=27.1317829457364, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325345, Length=215, Percent_Identity=28.3720930232558, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FLHF_TREPA (Q56339)

Other databases:

- EMBL:   U36839
- EMBL:   AE000520
- PIR:   E71290
- RefSeq:   NP_219150.1
- ProteinModelPortal:   Q56339
- SMR:   Q56339
- IntAct:   Q56339
- MINT:   MINT-6480084
- GeneID:   2610982
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0713
- NMPDR:   fig|243276.1.peg.709
- TIGR:   TP_0713
- HOGENOM:   HBG732082
- OMA:   TYANILN
- ProtClustDB:   CLSK218827
- BioCyc:   TPAL243276:TP_0713-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006
- SMART:   SM00382
- SMART:   SM00962
- TIGRFAMs:   TIGR03499

Pfam domain/function: PF00448 SRP54

EC number: NA

Molecular weight: Translated: 49284; Mature: 49284

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLVEVAPTKEKAIEKIRKKYGDRVNILRTQRNNRSFFFGLIERVSVEIFFSVNSGSQS
CCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHEEEEEEEEECCCCCC
SVHEIPSVQSRTRVSAARVEDTEAEKIKILESAQRINAKIAQQVEPLISAAKEKKTEKVP
HHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TSPEAVHALTQTLEGMIQKITNSAPVVIAQELQSIQRIELLLEENDFSFSFIRKSIARLK
CCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DELSYHDLESFEKVESTVLRWIIESVHIQVPPICTGTRNIVLVGPTGVGKTTTLAKLAAF
HHHCHHHHHHHHHHHHHHHHHHHHHHCEECCCEECCCCCEEEECCCCCCCHHHHHHHHHH
YFVTEPKRTGIQPRVKIITTDNFRIGAAFQMERYCELMGLDLCVVQAPVEFLTYMTLYQQ
HHEECCHHCCCCCEEEEEEECCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
ETDVVFVDTEGRSPVDGQNIERMVEYFRAVKNFELEVYLTIDAGSKANDLREVFKQYALF
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHH
EYRALIVTKLDETTSIGNLISALSEARTPITYITTGQTVPSNLEKASVNLLLSKLKGFKL
HHHHHHEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LAEEMGNDYGDYGSKER
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MELLVEVAPTKEKAIEKIRKKYGDRVNILRTQRNNRSFFFGLIERVSVEIFFSVNSGSQS
CCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHEEEEEEEEECCCCCC
SVHEIPSVQSRTRVSAARVEDTEAEKIKILESAQRINAKIAQQVEPLISAAKEKKTEKVP
HHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TSPEAVHALTQTLEGMIQKITNSAPVVIAQELQSIQRIELLLEENDFSFSFIRKSIARLK
CCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DELSYHDLESFEKVESTVLRWIIESVHIQVPPICTGTRNIVLVGPTGVGKTTTLAKLAAF
HHHCHHHHHHHHHHHHHHHHHHHHHHCEECCCEECCCCCEEEECCCCCCCHHHHHHHHHH
YFVTEPKRTGIQPRVKIITTDNFRIGAAFQMERYCELMGLDLCVVQAPVEFLTYMTLYQQ
HHEECCHHCCCCCEEEEEEECCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
ETDVVFVDTEGRSPVDGQNIERMVEYFRAVKNFELEVYLTIDAGSKANDLREVFKQYALF
CCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHH
EYRALIVTKLDETTSIGNLISALSEARTPITYITTGQTVPSNLEKASVNLLLSKLKGFKL
HHHHHHEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
LAEEMGNDYGDYGSKER
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9063647; 9665876