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The map label for this gene is sstT [H]

Identifier: 189025783

GI number: 189025783

Start: 602363

End: 603553

Strand: Reverse

Name: sstT [H]

Synonym: TPASS_0555

Alternate gene names: 189025783

Gene position: 603553-602363 (Counterclockwise)

Preceding gene: 189025784

Following gene: 189025780

Centisome position: 52.97

GC content: 54.49

Gene sequence:

>1191_bases
ATGGCCGGGAGTGCGGGGTTTTGGCTGCTCGCAAAGCTCAGTGGGGGGATGGTCTGTGGCGTTGCGCTCGGGCTGTGCGT
TAATGAGTCGGTCATGGCCATTATCCACACGGGGAAAACGCTTATCGGCGGGGTTGTTTTTTTTGTTATTCCCCTAGTTA
TTTTTGGTTTTATTGCCCCTACTGTCCTGAGTCTGAAAGCGAGTGCCGGTAGGATGCTAGGCTCGTTTCTGGTACTTTCC
TATCTCTCTTCGGTGGGTGCCTCCCTTTTTGCCACCGCGATGGGGCGTGTTGTTATCCCGTATCTTCGGATCCCGCGCAC
GGTGGAGGGTTTGCGTACAATCCCTAAGGTTATCTTTACCCTTGAGATTCCGTCTCTTATGCCCGTGGTCACTGCACTTG
CTTTTGCTCTCTTGGTGGGGCTGTCTGCCCTCTGGGTAAAAGCACGTGCGGTGGAGCAGGTGCTGTATGAATTTCGTCGC
ATGATGGGTGAAGCTATTAGCCGAGTGTTGGTGCCGCTGCTTCCCTTTTTTGTGGCGGCTACCTTCGCAGAACTTGCGTA
CAGCGGGAGTTTAACTCGTCAGCTGCCGCTTTTTGCCAAAGTGGTAGCGGTCGTCATTGTGGGTCATCTCCTGTGGCTGT
GCGTGTTGTACCTGGTGGGGTGGATACTGTCACGCAAAAATCCGTTCGAGGTACTTCGTCATTATGGAGCGGCGTATGCG
ACTGCGCTGGGCACGATGTCGAGTGCAGCAACACTGCCGGTTTCGTTACAATGTGCGCACAAGTCACGGGCACTGCCTGC
AGAAATTGTGGATTTTGCGATCCCGCTGGGTGCAACCACACATCTGTGCGGGTCTGTTCTGACGGAGACCTTTTTTTGTC
TAACGATAGCGCAGATGTTGTACGGGTCCATGCCCTCTCTTGCAGATATGGTGCTGTTCTCCTGTTTGTTCGGCATTTTT
GCCGTAGGTGCGCCGGGGGTTCCAGGGGGTACGGTGCTTGCGTCGCTCGGGCTGGTGCTTGATGTGTTGCACTTTGATAC
CACAGGAACCGGTTTGCTCATTGCGATATTTGCTTTGCAAGACAGTTTTGGGACTGCGTGTAACATCACTGGGGATGGCG
CCCTGGCACTGATGCTGCGTGGACTTCGCTATACCCTGCGGGCGAACTGCGTTGGGCGTGAAGAGAAGTAG

Upstream 100 bases:

>100_bases
CGCCTTCGAGGTTGGTTCTATGACATAAAAAGACCGCTGACCTGTTATCAGAGGATAGTCTTTTTGGTATACTGCCGGCG
CGTGTGCGGAGGAGGACGCT

Downstream 100 bases:

>100_bases
CGGCTCGTGCCCTGCAGGGATCCGGGAGCGTCGTGCGCTCCGTCTGAGTTTGTACCCGCGAGTCTAGAAAGAAAGGTGCT
GGAGTAACTCGGCGGGCGTC

Product: glutamate/aspartate transporter

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MAGSAGFWLLAKLSGGMVCGVALGLCVNESVMAIIHTGKTLIGGVVFFVIPLVIFGFIAPTVLSLKASAGRMLGSFLVLS
YLSSVGASLFATAMGRVVIPYLRIPRTVEGLRTIPKVIFTLEIPSLMPVVTALAFALLVGLSALWVKARAVEQVLYEFRR
MMGEAISRVLVPLLPFFVAATFAELAYSGSLTRQLPLFAKVVAVVIVGHLLWLCVLYLVGWILSRKNPFEVLRHYGAAYA
TALGTMSSAATLPVSLQCAHKSRALPAEIVDFAIPLGATTHLCGSVLTETFFCLTIAQMLYGSMPSLADMVLFSCLFGIF
AVGAPGVPGGTVLASLGLVLDVLHFDTTGTGLLIAIFALQDSFGTACNITGDGALALMLRGLRYTLRANCVGREEK

Sequences:

>Translated_396_residues
MAGSAGFWLLAKLSGGMVCGVALGLCVNESVMAIIHTGKTLIGGVVFFVIPLVIFGFIAPTVLSLKASAGRMLGSFLVLS
YLSSVGASLFATAMGRVVIPYLRIPRTVEGLRTIPKVIFTLEIPSLMPVVTALAFALLVGLSALWVKARAVEQVLYEFRR
MMGEAISRVLVPLLPFFVAATFAELAYSGSLTRQLPLFAKVVAVVIVGHLLWLCVLYLVGWILSRKNPFEVLRHYGAAYA
TALGTMSSAATLPVSLQCAHKSRALPAEIVDFAIPLGATTHLCGSVLTETFFCLTIAQMLYGSMPSLADMVLFSCLFGIF
AVGAPGVPGGTVLASLGLVLDVLHFDTTGTGLLIAIFALQDSFGTACNITGDGALALMLRGLRYTLRANCVGREEK
>Mature_395_residues
AGSAGFWLLAKLSGGMVCGVALGLCVNESVMAIIHTGKTLIGGVVFFVIPLVIFGFIAPTVLSLKASAGRMLGSFLVLSY
LSSVGASLFATAMGRVVIPYLRIPRTVEGLRTIPKVIFTLEIPSLMPVVTALAFALLVGLSALWVKARAVEQVLYEFRRM
MGEAISRVLVPLLPFFVAATFAELAYSGSLTRQLPLFAKVVAVVIVGHLLWLCVLYLVGWILSRKNPFEVLRHYGAAYAT
ALGTMSSAATLPVSLQCAHKSRALPAEIVDFAIPLGATTHLCGSVLTETFFCLTIAQMLYGSMPSLADMVLFSCLFGIFA
VGAPGVPGGTVLASLGLVLDVLHFDTTGTGLLIAIFALQDSFGTACNITGDGALALMLRGLRYTLRANCVGREEK

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI169790839, Length=272, Percent_Identity=28.3088235294118, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI223468566, Length=224, Percent_Identity=31.25, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI223468564, Length=224, Percent_Identity=31.25, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI5032093, Length=224, Percent_Identity=31.25, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI21314632, Length=201, Percent_Identity=31.8407960199005, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI66773030, Length=251, Percent_Identity=28.6852589641434, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI40254478, Length=180, Percent_Identity=32.7777777777778, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI4827012, Length=252, Percent_Identity=30.1587301587302, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI262359914, Length=178, Percent_Identity=30.8988764044944, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI194239697, Length=198, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71983106, Length=261, Percent_Identity=26.8199233716475, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71983099, Length=261, Percent_Identity=26.8199233716475, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71996953, Length=203, Percent_Identity=31.5270935960591, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193206505, Length=165, Percent_Identity=32.7272727272727, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17537407, Length=200, Percent_Identity=30.5, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17541374, Length=151, Percent_Identity=32.4503311258278, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193206654, Length=161, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583025, Length=235, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17137668, Length=235, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24583023, Length=235, Percent_Identity=27.6595744680851, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 41916; Mature: 41785

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AGSAGFWLLAKLSGGMVCGVALGLCVNESVMAIIHTGKTLIGGVVFFVIPLVIFGFIAP
CCCCHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
TVLSLKASAGRMLGSFLVLSYLSSVGASLFATAMGRVVIPYLRIPRTVEGLRTIPKVIFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LEIPSLMPVVTALAFALLVGLSALWVKARAVEQVLYEFRRMMGEAISRVLVPLLPFFVAA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFAELAYSGSLTRQLPLFAKVVAVVIVGHLLWLCVLYLVGWILSRKNPFEVLRHYGAAYA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TALGTMSSAATLPVSLQCAHKSRALPAEIVDFAIPLGATTHLCGSVLTETFFCLTIAQML
HHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
YGSMPSLADMVLFSCLFGIFAVGAPGVPGGTVLASLGLVLDVLHFDTTGTGLLIAIFALQ
HCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
DSFGTACNITGDGALALMLRGLRYTLRANCVGREEK
HCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]