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The map label for this gene is trkA [H]

Identifier: 189025743

GI number: 189025743

Start: 550377

End: 551777

Strand: Direct

Name: trkA [H]

Synonym: TPASS_0513

Alternate gene names: 189025743

Gene position: 550377-551777 (Clockwise)

Preceding gene: 189025742

Following gene: 189025744

Centisome position: 48.3

GC content: 50.96

Gene sequence:

>1401_bases
ATGAGGGTTATTGTTGTTGGATGCGGTACGAATGGGCGTGAACTTACGCGTCGTTTGAGCGCGAGGGGACATCAGGTTAC
GCTTGTTGCTGCCGCGCATGAGCCTGTCCCCCGTAAAATTCCCGCGGGGGCACAAGCGCTCGTGCGTCATCAAAAAGATC
ACCGCGCTACCCTGGGTGAGGCAGGTATCGCAAAGGCACAGGCGTTTGTTGCGGTCACCGAGGTTGACGAACTTAACATA
GTACTGTGTGGTATAGCCGCCGACTTGAATGCCGGAGTGATTAAAATAGCCCAAACGCACGATGACCACTACGCTCACGC
GGTGTGTCGTGAGTCGCGCTGTATTTTTGGTATTGACTTTCTCATATCTGCGGATAAGGAAGCGATGCGTGCGGTAGTGA
GCACCGTCGAGCAGGGTGCCATCAGCGATGTCATCCCATTGAAAAATGCACCGTATGAAATTGCCCGTTTTCCTATTGCA
AAGGGCAGCGGCCTCGATGGTATCACGCTCTCTGATATGCGTCGTCTGGTAAAAATTTCTTTTGTTGCCGTTGCTTTTGA
AGTTCGGGGGAGGAGTGTAATTCCCTCAGGGGAGACCATGCTCGCTTCTGGTATGCGCCTGTCAGTACTCTGTGCGCCTG
AACATATGGGACGTTTTTATGAGCTGGCGGGTTTTAAAATACATCCGGTAAAAAAAATTGCACTCATTGGCATGAGCGCG
GTAGGTACGCTCGTGGCACAGGATGTAGCAGAAAAATGCAAGCCGCACTTTTTCAGTAGTGCCTTCAGTCTTTCTCCAAG
GGAGCGTGCGAGTCTTGTATTGGTTGATAAGAGTGAAACGGCAACCCAGGCAGTGTGTGCTCAATTTCCGCACGTTACTG
CCTATCATGGTGATGTCACAGATGAGGCTTTTTTCGCAGAGATTACGCCGGACACGTTTGATCTGGTGATTACCACCACT
AATAACTATGAGCTGAATATGATTACAGCCGCATACATGAAGACGCTCGGAGTGCCTCGGGCTGTTGCATTGGTACACAG
CTCCCTTATGGAGGATATTGCGGGGAAAATTGGCATCGATGTTGCTGTTTCTTATCAAGACGTAGTGGTTGACGCTATTA
TGAGCCATTTGGCCGGTTCCCACGTCACTGGCATACATACTATCGGCGACGGATCGCTAGAAATCGTTGAGTTCGCTATT
TCCGCGCAGTCCCCCCTGGTAGGCAAGCGCCTGAAGGATATCGCTGTGCACGGAAGCTTCTTGGTGCTGCTCATCTCAAC
GGTGCGTGGCTCTTTCATTCCTTCAGGAGATACGGTTCTGCTTGAGGGAAGTGTGCTGATGTTCATCGTACAGTCTGCGC
AGAGTGAAAAAATTGTCGCGTTGCTTGGAGGAACGGTGTAA

Upstream 100 bases:

>100_bases
GTAGTGGTACTTTTGAAAAAGATATGAGTGGCAGGCGTTGTGCGCCGTGTTCTGCGCGCTGGCCATGCAAAAAAATTTCG
TGCTACTATGGCCTTCGGAC

Downstream 100 bases:

>100_bases
TGCGGTCTGCCGCGAAGGGAGTGGAATTGCATAAAGCATAAAAATTGCGCATAGTCTGCCCTCTTATGGATGGGGATCGC
GTAGAAAGGGAGAACGTGTC

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA homolog 1 [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MRVIVVGCGTNGRELTRRLSARGHQVTLVAAAHEPVPRKIPAGAQALVRHQKDHRATLGEAGIAKAQAFVAVTEVDELNI
VLCGIAADLNAGVIKIAQTHDDHYAHAVCRESRCIFGIDFLISADKEAMRAVVSTVEQGAISDVIPLKNAPYEIARFPIA
KGSGLDGITLSDMRRLVKISFVAVAFEVRGRSVIPSGETMLASGMRLSVLCAPEHMGRFYELAGFKIHPVKKIALIGMSA
VGTLVAQDVAEKCKPHFFSSAFSLSPRERASLVLVDKSETATQAVCAQFPHVTAYHGDVTDEAFFAEITPDTFDLVITTT
NNYELNMITAAYMKTLGVPRAVALVHSSLMEDIAGKIGIDVAVSYQDVVVDAIMSHLAGSHVTGIHTIGDGSLEIVEFAI
SAQSPLVGKRLKDIAVHGSFLVLLISTVRGSFIPSGDTVLLEGSVLMFIVQSAQSEKIVALLGGTV

Sequences:

>Translated_466_residues
MRVIVVGCGTNGRELTRRLSARGHQVTLVAAAHEPVPRKIPAGAQALVRHQKDHRATLGEAGIAKAQAFVAVTEVDELNI
VLCGIAADLNAGVIKIAQTHDDHYAHAVCRESRCIFGIDFLISADKEAMRAVVSTVEQGAISDVIPLKNAPYEIARFPIA
KGSGLDGITLSDMRRLVKISFVAVAFEVRGRSVIPSGETMLASGMRLSVLCAPEHMGRFYELAGFKIHPVKKIALIGMSA
VGTLVAQDVAEKCKPHFFSSAFSLSPRERASLVLVDKSETATQAVCAQFPHVTAYHGDVTDEAFFAEITPDTFDLVITTT
NNYELNMITAAYMKTLGVPRAVALVHSSLMEDIAGKIGIDVAVSYQDVVVDAIMSHLAGSHVTGIHTIGDGSLEIVEFAI
SAQSPLVGKRLKDIAVHGSFLVLLISTVRGSFIPSGDTVLLEGSVLMFIVQSAQSEKIVALLGGTV
>Mature_466_residues
MRVIVVGCGTNGRELTRRLSARGHQVTLVAAAHEPVPRKIPAGAQALVRHQKDHRATLGEAGIAKAQAFVAVTEVDELNI
VLCGIAADLNAGVIKIAQTHDDHYAHAVCRESRCIFGIDFLISADKEAMRAVVSTVEQGAISDVIPLKNAPYEIARFPIA
KGSGLDGITLSDMRRLVKISFVAVAFEVRGRSVIPSGETMLASGMRLSVLCAPEHMGRFYELAGFKIHPVKKIALIGMSA
VGTLVAQDVAEKCKPHFFSSAFSLSPRERASLVLVDKSETATQAVCAQFPHVTAYHGDVTDEAFFAEITPDTFDLVITTT
NNYELNMITAAYMKTLGVPRAVALVHSSLMEDIAGKIGIDVAVSYQDVVVDAIMSHLAGSHVTGIHTIGDGSLEIVEFAI
SAQSPLVGKRLKDIAVHGSFLVLLISTVRGSFIPSGDTVLLEGSVLMFIVQSAQSEKIVALLGGTV

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=462, Percent_Identity=23.5930735930736, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 49642; Mature: 49642

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIVVGCGTNGRELTRRLSARGHQVTLVAAAHEPVPRKIPAGAQALVRHQKDHRATLGE
CEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCC
AGIAKAQAFVAVTEVDELNIVLCGIAADLNAGVIKIAQTHDDHYAHAVCRESRCIFGIDF
CCHHHHHEEEEEEECCCCEEEEEEEECCCCCCEEEEEECCCCHHHHHHHHCCCEEEEEEE
LISADKEAMRAVVSTVEQGAISDVIPLKNAPYEIARFPIAKGSGLDGITLSDMRRLVKIS
EEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHH
FVAVAFEVRGRSVIPSGETMLASGMRLSVLCAPEHMGRFYELAGFKIHPVKKIALIGMSA
HEEEEEEECCCEECCCCCHHHHCCCEEEEEECHHHHCCHHHHCCCEECCHHHEEEECHHH
VGTLVAQDVAEKCKPHFFSSAFSLSPRERASLVLVDKSETATQAVCAQFPHVTAYHGDVT
HHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEECCCCC
DEAFFAEITPDTFDLVITTTNNYELNMITAAYMKTLGVPRAVALVHSSLMEDIAGKIGID
CCCEEEEECCCCEEEEEEECCCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCE
VAVSYQDVVVDAIMSHLAGSHVTGIHTIGDGSLEIVEFAISAQSPLVGKRLKDIAVHGSF
EEECHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHCCHH
LVLLISTVRGSFIPSGDTVLLEGSVLMFIVQSAQSEKIVALLGGTV
HHHHHHHHCCCCCCCCCEEEEECCEEEEEECCCCCCEEEEEECCCC
>Mature Secondary Structure
MRVIVVGCGTNGRELTRRLSARGHQVTLVAAAHEPVPRKIPAGAQALVRHQKDHRATLGE
CEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCC
AGIAKAQAFVAVTEVDELNIVLCGIAADLNAGVIKIAQTHDDHYAHAVCRESRCIFGIDF
CCHHHHHEEEEEEECCCCEEEEEEEECCCCCCEEEEEECCCCHHHHHHHHCCCEEEEEEE
LISADKEAMRAVVSTVEQGAISDVIPLKNAPYEIARFPIAKGSGLDGITLSDMRRLVKIS
EEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHH
FVAVAFEVRGRSVIPSGETMLASGMRLSVLCAPEHMGRFYELAGFKIHPVKKIALIGMSA
HEEEEEEECCCEECCCCCHHHHCCCEEEEEECHHHHCCHHHHCCCEECCHHHEEEECHHH
VGTLVAQDVAEKCKPHFFSSAFSLSPRERASLVLVDKSETATQAVCAQFPHVTAYHGDVT
HHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCEEEECCCCC
DEAFFAEITPDTFDLVITTTNNYELNMITAAYMKTLGVPRAVALVHSSLMEDIAGKIGID
CCCEEEEECCCCEEEEEEECCCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCE
VAVSYQDVVVDAIMSHLAGSHVTGIHTIGDGSLEIVEFAISAQSPLVGKRLKDIAVHGSF
EEECHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHCCHH
LVLLISTVRGSFIPSGDTVLLEGSVLMFIVQSAQSEKIVALLGGTV
HHHHHHHHCCCCCCCCCEEEEECCEEEEEECCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8268235; 12125824 [H]