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The map label for this gene is hxk

Identifier: 189025735

GI number: 189025735

Start: 540494

End: 541828

Strand: Reverse

Name: hxk

Synonym: TPASS_0505

Alternate gene names: NA

Gene position: 541828-540494 (Counterclockwise)

Preceding gene: 189025740

Following gene: 189025718

Centisome position: 47.55

GC content: 53.63

Gene sequence:

>1335_bases
ATGGATCAGCATACACGTACACGCGATCTTGTTTCTGCATTTTTTGGGCGCTTTCACTTTGATGTCCAGGGACCTTCCGT
CCGCACGGTTGTCGACGTGTTGCGCGCAGATATGGTGCGCGGCTTAGAGGAAGAGGCGCAGCTTCCTCCCCGTATGGGGA
GTGCACTTGCGATGATTCCCACTTGGGTGGCGCCCCCCCGTGTATCCCCCTGCAACCGACGCGTGATAGTTATCGACGCT
GGAGGAACCAACTTTCGCTCGTGCCTCGTACGCTTCGGCGACAGTGGCACACCTCACATCGAGAATTTAGAAAAACGTCC
CATGCCCGGTACCACCCGTGAGTACTCAAGGACAGAGTTTTTTGGAGAAATTGCAGACAACCTGGCACGTCTGAAAGGTG
CAGCGGACTGCATTGGCTTTTGTTTCTCTTACCCTATTCGTATCAGACCTGACGGTGACGGTGAGGTTATTCAGTTTGCG
AAGGAAATCAAAGCTGCTGAGGTCATCGGCACGTGTGTCGGTGCTGGTTTGACAGAAGCGCTAAGTGCTCGGAACTGGCC
TGAACTCCGTTCTCTCAAAATGCTCAATGACGCAACGAGTGCGCTGCTTGCAGGTTTTTTTGCGGCACCAGAGGGGTGTT
CGTTCAGTTCATACGTAGGTTTTATTCTTGGCACTGGAATGAATTCTGCGTATCTGGAGCCAGACCCTATTCCTAAAATT
CCTGCGCATCACACACCTCAGGTGGTAGTGTGCGAATCGGGAAAAAGCAACAAAGTACCGCGCAGTGTCTTTGACGAATT
ATTCACTCAAACTACTGCCGAGCCGGATATTGCACACCTAGAGAAGATGTCCTCGGGCACCTACCTCGGTCCCCTTGCTT
CCGTTGTCGTGCGGCTTGCGGCACAAGAAGGTCTTTTCTCACACGCAGTACACGCTGCACTCAGTACGGTTTCCTTTACA
CTCGTGGATATGGATCGTTTTTTATTTGCTCCCTCTGTGTCCACCACCACGTTGGGCGCGTTGCTCGCACCGGGCACCGA
CACAGACCGAGAGATTCTCTTTCTTTTGCTCGATGCGGTAGTTGCACGTGCAGCACGCATCGCTGCGGGAGTAATCGCCG
CCTCAGTATTAAAAAGCGGTGCTGGGTATGATCCGCTTCGTCCCGTGTGCGTGCTCGCAGAAGGCACCACGTTCCAACGC
ACCTACCGCCTACGCACCCGGGTTACTTCCCACCTGCAAGCCTTTTTGACTGAGGAGCGCGGTGTGTATTTCGATATCAT
TTCACTTGAAAACGCCGTAACGCTCGGCTCTGCACTCGGAGGACTCAGTTCGTAG

Upstream 100 bases:

>100_bases
ATAAACTCCCTGCCCCATACGCCGGCACCCCTTTTTTGCAGGAACGGTTTCCTAAACGAGCTATCCGTGCTACCCTGGCA
GCCGACCAGGGAGGGCGCGT

Downstream 100 bases:

>100_bases
GCATATGCCTAAACGGACTGATGATCCTGTGAGAGATAGCGCCGTGCAGTGCTTCCTGTCATCTTCTCGTCGGCCGCGTG
TGGCTGAGCGGCCGTGCTCG

Product: hexokinase

Products: ADP; D-hexose 6-phosphate

Alternate protein names: Hexokinase Type III; Hexokinase Family Protein

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MDQHTRTRDLVSAFFGRFHFDVQGPSVRTVVDVLRADMVRGLEEEAQLPPRMGSALAMIPTWVAPPRVSPCNRRVIVIDA
GGTNFRSCLVRFGDSGTPHIENLEKRPMPGTTREYSRTEFFGEIADNLARLKGAADCIGFCFSYPIRIRPDGDGEVIQFA
KEIKAAEVIGTCVGAGLTEALSARNWPELRSLKMLNDATSALLAGFFAAPEGCSFSSYVGFILGTGMNSAYLEPDPIPKI
PAHHTPQVVVCESGKSNKVPRSVFDELFTQTTAEPDIAHLEKMSSGTYLGPLASVVVRLAAQEGLFSHAVHAALSTVSFT
LVDMDRFLFAPSVSTTTLGALLAPGTDTDREILFLLLDAVVARAARIAAGVIAASVLKSGAGYDPLRPVCVLAEGTTFQR
TYRLRTRVTSHLQAFLTEERGVYFDIISLENAVTLGSALGGLSS

Sequences:

>Translated_444_residues
MDQHTRTRDLVSAFFGRFHFDVQGPSVRTVVDVLRADMVRGLEEEAQLPPRMGSALAMIPTWVAPPRVSPCNRRVIVIDA
GGTNFRSCLVRFGDSGTPHIENLEKRPMPGTTREYSRTEFFGEIADNLARLKGAADCIGFCFSYPIRIRPDGDGEVIQFA
KEIKAAEVIGTCVGAGLTEALSARNWPELRSLKMLNDATSALLAGFFAAPEGCSFSSYVGFILGTGMNSAYLEPDPIPKI
PAHHTPQVVVCESGKSNKVPRSVFDELFTQTTAEPDIAHLEKMSSGTYLGPLASVVVRLAAQEGLFSHAVHAALSTVSFT
LVDMDRFLFAPSVSTTTLGALLAPGTDTDREILFLLLDAVVARAARIAAGVIAASVLKSGAGYDPLRPVCVLAEGTTFQR
TYRLRTRVTSHLQAFLTEERGVYFDIISLENAVTLGSALGGLSS
>Mature_444_residues
MDQHTRTRDLVSAFFGRFHFDVQGPSVRTVVDVLRADMVRGLEEEAQLPPRMGSALAMIPTWVAPPRVSPCNRRVIVIDA
GGTNFRSCLVRFGDSGTPHIENLEKRPMPGTTREYSRTEFFGEIADNLARLKGAADCIGFCFSYPIRIRPDGDGEVIQFA
KEIKAAEVIGTCVGAGLTEALSARNWPELRSLKMLNDATSALLAGFFAAPEGCSFSSYVGFILGTGMNSAYLEPDPIPKI
PAHHTPQVVVCESGKSNKVPRSVFDELFTQTTAEPDIAHLEKMSSGTYLGPLASVVVRLAAQEGLFSHAVHAALSTVSFT
LVDMDRFLFAPSVSTTTLGALLAPGTDTDREILFLLLDAVVARAARIAAGVIAASVLKSGAGYDPLRPVCVLAEGTTFQR
TYRLRTRVTSHLQAFLTEERGVYFDIISLENAVTLGSALGGLSS

Specific function: Unknown

COG id: COG5026

COG function: function code G; Hexokinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI194097330, Length=405, Percent_Identity=26.6666666666667, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI156151420, Length=314, Percent_Identity=26.4331210191083, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI15553127, Length=408, Percent_Identity=23.7745098039216, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4503951, Length=411, Percent_Identity=25.3041362530414, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI15967159, Length=411, Percent_Identity=25.3041362530414, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI15967161, Length=411, Percent_Identity=25.3041362530414, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI188497750, Length=408, Percent_Identity=24.0196078431373, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI188497754, Length=408, Percent_Identity=24.0196078431373, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI15991829, Length=408, Percent_Identity=24.0196078431373, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI15991831, Length=408, Percent_Identity=24.0196078431373, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI15991827, Length=408, Percent_Identity=24.0196078431373, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71983705, Length=328, Percent_Identity=27.1341463414634, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71983713, Length=307, Percent_Identity=27.3615635179153, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17507937, Length=310, Percent_Identity=23.8709677419355, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319809, Length=394, Percent_Identity=25.8883248730964, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6321184, Length=426, Percent_Identity=23.4741784037559, Blast_Score=93, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6321168, Length=411, Percent_Identity=25.5474452554745, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320724, Length=382, Percent_Identity=23.8219895287958, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45551986, Length=451, Percent_Identity=22.6164079822616, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24640843, Length=392, Percent_Identity=23.9795918367347, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI18079297, Length=392, Percent_Identity=23.9795918367347, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.1

Molecular weight: Translated: 47845; Mature: 47845

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQHTRTRDLVSAFFGRFHFDVQGPSVRTVVDVLRADMVRGLEEEAQLPPRMGSALAMIP
CCCCHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHCC
TWVAPPRVSPCNRRVIVIDAGGTNFRSCLVRFGDSGTPHIENLEKRPMPGTTREYSRTEF
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCHHHHHHH
FGEIADNLARLKGAADCIGFCFSYPIRIRPDGDGEVIQFAKEIKAAEVIGTCVGAGLTEA
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
LSARNWPELRSLKMLNDATSALLAGFFAAPEGCSFSSYVGFILGTGMNSAYLEPDPIPKI
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PAHHTPQVVVCESGKSNKVPRSVFDELFTQTTAEPDIAHLEKMSSGTYLGPLASVVVRLA
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHH
AQEGLFSHAVHAALSTVSFTLVDMDRFLFAPSVSTTTLGALLAPGTDTDREILFLLLDAV
HHHHHHHHHHHHHHHHHHHHEEEHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
VARAARIAAGVIAASVLKSGAGYDPLRPVCVLAEGTTFQRTYRLRTRVTSHLQAFLTEER
HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
GVYFDIISLENAVTLGSALGGLSS
CCEEEEEECCCHHHHHHHHCCCCC
>Mature Secondary Structure
MDQHTRTRDLVSAFFGRFHFDVQGPSVRTVVDVLRADMVRGLEEEAQLPPRMGSALAMIP
CCCCHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHCC
TWVAPPRVSPCNRRVIVIDAGGTNFRSCLVRFGDSGTPHIENLEKRPMPGTTREYSRTEF
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCHHHHHHH
FGEIADNLARLKGAADCIGFCFSYPIRIRPDGDGEVIQFAKEIKAAEVIGTCVGAGLTEA
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
LSARNWPELRSLKMLNDATSALLAGFFAAPEGCSFSSYVGFILGTGMNSAYLEPDPIPKI
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
PAHHTPQVVVCESGKSNKVPRSVFDELFTQTTAEPDIAHLEKMSSGTYLGPLASVVVRLA
CCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHH
AQEGLFSHAVHAALSTVSFTLVDMDRFLFAPSVSTTTLGALLAPGTDTDREILFLLLDAV
HHHHHHHHHHHHHHHHHHHHEEEHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
VARAARIAAGVIAASVLKSGAGYDPLRPVCVLAEGTTFQRTYRLRTRVTSHLQAFLTEER
HHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
GVYFDIISLENAVTLGSALGGLSS
CCEEEEEECCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-hexose

Specific reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA