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The map label for this gene is atpE

Identifier: 189025657

GI number: 189025657

Start: 453110

End: 453808

Strand: Direct

Name: atpE

Synonym: TPASS_0424

Alternate gene names: 189025657

Gene position: 453110-453808 (Clockwise)

Preceding gene: 189025656

Following gene: 189025658

Centisome position: 39.77

GC content: 56.65

Gene sequence:

>699_bases
TTGCTTGGTGAGTCGCGTGAGGAGGCAGAGCGGATTGTCCGCGCTGCGCGTGAGGAGGCAGAGCGGATTGTCCGCGCTGC
GCGTGAGGAGGCAGAGCGGATCGAGTCGTCGTCTCTTGCGGCGCTGTCGCAGGCGAGTCGCAACGTTTTATTATCCTTTC
AAGATTCGGTGACTCGCTCTCTTCGGGCTATTATTTCGATGGAGACGGCGCAAGCCTACGATGCGGGTGTTTTGCGTGAG
CTTATTCCTCGTGTCGTTTCTGCCTGGGTTCAAGCGGAGGGTGATAAGCTAGAGCTCATCCTCTCTCCTGCTGATCTTCG
GACGCTTGAGGGGGTGTTTTGTGCTGCGTTGCAGGAGCAGCTTTCGGCAGGGGTAGAGTTGAGGTCTGACGATTGCCTTA
CGGCAGGGTTTAGGATAGTCCCTGCCGAGGGCGGGTCGTACTATGATTTTTCCGCCGCCGCGGTTGCTCAGTTGTTCTCT
TCGTATGTTTCTGCGCGTGTTGCCGAGGTGCTCAGTCTGCTGCGCAGGAGCTGTGATGTCTTCCTATTGCTACCTTATAA
CGCAGCTACCATCTCTTCTATGCGGCGCGGTGCCTCCTTTGCGTTATCAGGATTTTTTGGATTGTGCGCTACGTTTCTTG
GGTCGGCAGGATGCTGCGGTGCTTGGAAATATCTCGTTGTGTCCCGTGCCGGCGCGTGA

Upstream 100 bases:

>100_bases
GAGGGCTGCGAGGAGAACGTATAGTGGAGATTCAACTGCAAGATCTGATTGACCGAATTAAGCGCGAAGCGTTGCCTCTT
CCGAGGAGCAGGCGTCTCGT

Downstream 100 bases:

>100_bases
CTCCACGGGATCGCGTGTTTTAGATAGATGGGGCGAGTTTGAGTACGCGTTACGCTGTGCGCTTGCGCGTGAGCGCGCGG
ACCGTCTGCGGTGGGATACT

Product: V-type ATP synthase subunit E

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit E

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MLGESREEAERIVRAAREEAERIVRAAREEAERIESSSLAALSQASRNVLLSFQDSVTRSLRAIISMETAQAYDAGVLRE
LIPRVVSAWVQAEGDKLELILSPADLRTLEGVFCAALQEQLSAGVELRSDDCLTAGFRIVPAEGGSYYDFSAAAVAQLFS
SYVSARVAEVLSLLRRSCDVFLLLPYNAATISSMRRGASFALSGFFGLCATFLGSAGCCGAWKYLVVSRAGA

Sequences:

>Translated_232_residues
MLGESREEAERIVRAAREEAERIVRAAREEAERIESSSLAALSQASRNVLLSFQDSVTRSLRAIISMETAQAYDAGVLRE
LIPRVVSAWVQAEGDKLELILSPADLRTLEGVFCAALQEQLSAGVELRSDDCLTAGFRIVPAEGGSYYDFSAAAVAQLFS
SYVSARVAEVLSLLRRSCDVFLLLPYNAATISSMRRGASFALSGFFGLCATFLGSAGCCGAWKYLVVSRAGA
>Mature_232_residues
MLGESREEAERIVRAAREEAERIVRAAREEAERIESSSLAALSQASRNVLLSFQDSVTRSLRAIISMETAQAYDAGVLRE
LIPRVVSAWVQAEGDKLELILSPADLRTLEGVFCAALQEQLSAGVELRSDDCLTAGFRIVPAEGGSYYDFSAAAVAQLFS
SYVSARVAEVLSLLRRSCDVFLLLPYNAATISSMRRGASFALSGFFGLCATFLGSAGCCGAWKYLVVSRAGA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG1390

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit E

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase E subunit family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VATE_TREPA (O83439)

Other databases:

- EMBL:   AE000520
- PIR:   E71325
- RefSeq:   NP_218864.1
- ProteinModelPortal:   O83439
- IntAct:   O83439
- GeneID:   2610920
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0424
- NMPDR:   fig|243276.1.peg.423
- TIGR:   TP_0424
- HOGENOM:   HBG732009
- OMA:   MQFEVKD
- BioCyc:   TPAL243276:TP_0424-MONOMER
- BRENDA:   3.6.3.14
- HAMAP:   MF_00311

Pfam domain/function: NA

EC number: 3.6.3.14

Molecular weight: Translated: 24978; Mature: 24978

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGESREEAERIVRAAREEAERIVRAAREEAERIESSSLAALSQASRNVLLSFQDSVTRS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHH
LRAIISMETAQAYDAGVLRELIPRVVSAWVQAEGDKLELILSPADLRTLEGVFCAALQEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHH
LSAGVELRSDDCLTAGFRIVPAEGGSYYDFSAAAVAQLFSSYVSARVAEVLSLLRRSCDV
HHCCCEECCCCCHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
FLLLPYNAATISSMRRGASFALSGFFGLCATFLGSAGCCGAWKYLVVSRAGA
EEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MLGESREEAERIVRAAREEAERIVRAAREEAERIESSSLAALSQASRNVLLSFQDSVTRS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHH
LRAIISMETAQAYDAGVLRELIPRVVSAWVQAEGDKLELILSPADLRTLEGVFCAALQEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHH
LSAGVELRSDDCLTAGFRIVPAEGGSYYDFSAAAVAQLFSSYVSARVAEVLSLLRRSCDV
HHCCCEECCCCCHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
FLLLPYNAATISSMRRGASFALSGFFGLCATFLGSAGCCGAWKYLVVSRAGA
EEEECCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876