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The map label for this gene is secD

Identifier: 189025643

GI number: 189025643

Start: 436637

End: 438388

Strand: Direct

Name: secD

Synonym: TPASS_0410

Alternate gene names: 189025643

Gene position: 436637-438388 (Clockwise)

Preceding gene: 189025642

Following gene: 189025644

Centisome position: 38.32

GC content: 53.6

Gene sequence:

>1752_bases
GTGAGTAAGAAGGCTCGGTTTGGGGTCGTGCTTGTTGTTCTTGCTGCGTGCTCTGGGTTTTTGTTCCCTACACTCCAGTG
GTATTTTCTGACCGACGCACAAACGCGGCAGCGTGCGCTCAGCTCGCGCGAGCAGATAAAAGAGTACGCTGTGCAGAGTG
CTGAGCGTGATCTTGCGGATTTAACCCGTCTTGCGCGTGCGGGGTCGGATGAGGATATCTCAGCGCGTTATGCACCGCTT
GTTGCCGCTGCGCGCCAGAATCTTTCTTATTCGGGCAGACCGGCCCCTTCTCGCTGGACCGCTGCGGCACTCGTTTCTGC
ATTCCCCGTAAAAAGCGAGCAGGGTTTTGTTCTTTACGCGCGACCGTTGATGGAGCAGACGTACCGGGAAGCCGTCCTGA
AGATGAAAAGGAGACAGGCCCAAGCTGTCAAGCTCGGGCTTGATCTTTCCGGCGGCACTAGCGTGGTGATTAAAGCTGAT
TTGAGCGAAGTTACCAAGGGAGTTCCGGATGCAGAGCGCGCCGCAATACGCAGCGAAGCGATGGCGCTGGTGCTTAGTAC
CCTTGAGAATCGTATTAATCGCTTTGGTCTTTCTGAGCCCGTTATTCGGAGGCAAGGGGAAGATCGCGTGTATGTGGAGA
TTCCTGGTCTTACTGACCGTGACCGTGTTCATTCTATCGTCATGGGTCGTGGTGTCCTGGCGTTTCATCTCGTGGATGAT
GATGCGACTCAAAAGCTTCTCGATCACTATCGCAATAACCCGCAGGGTACCTTCGACGCTGCGCATCAGTTGCACGATCT
GTCTCTGGTTCCTGAGCACACCAGTGTGCTCGGAGTATATCGCAAGGATTCCTACGGACTTGATGTGCGCGACGGGTTTC
TGGTTGTTAAGAAGGAGCCTGCGCTTGAAGGAAGACATATTCGTGATGCAACGGTGAGCTCAGGTCGCGCGAACGAGCCG
TTGGTGCTGTTTGACCTGGACCATGAAGGAGCGCGTATTTTTTCGGAACTTACCACTAAGGAGATAGGGCGTCGCCTTGC
AATTGTCTCTGACGGTAAAATTAGGTCTGCCCCTGCTATCCGGGAGCCGATAACAGCGGGCTCAGGGAGTATCAGTGGAT
TCAGTGCAGAAGAGGCGCAAAATCTGAAAACCGCGCTGCGCAGCGCCTGGTTAAACGTTGCGCTTGAAATAGAAAATCAG
CAGGTTGTCGGGGCGAGTATGGGGGAAGAGAGTATTCGGCAGGGTACGCGCGCGCTGGTGTGGGGGCTGTGCGCGGTGCT
CTTATTTATGCTGGTGTGGTATCAAGAAGCGGGCGTAAACGCTTGTGTCGCGCAGCTTTTGAATCTGTATATCATGTTCG
GTGTGCTTTCAGCGTTTAATTTGACGCTTACGCTTTCGAGTATCGCGGGGATGATTCTCACTATTGGTATGGCAGTGGAT
GCGAATGTCGTTGTCTTTGAGCGTATACGGGAAGAACTTGCGCTGGGCAAAAGCCGCGGGGCTGCTGTGTGTAGCGGCTT
TGAGCGTGCGTTTTGGGCAATTATGGATTCAAACGTGACGACGTTTATAGCAGCGCTTTTCCTTTCGGTGCTCGGTACCG
GTCCTATTAAGGGTTTCGCATACAGTTTGGCTATCGGGGTGGTGTCCTCCGTATTTACGGCATTGTTCGTTTCCCGTCTG
ATGTTTGACTACGGGACGGAGGTTTTACACAAAAAGACCGTGCGCATTGGATGGAGGATTGCTCGCGTATGA

Upstream 100 bases:

>100_bases
TTGCGCGCATAAACGACAGGAGAGGTGTTTCGAATCCTAAGACAGATTGCGATTCGAAGCCCGGCGTGCCCCTGACAGGT
GTGGACAAGGAGATCGCCAG

Downstream 100 bases:

>100_bases
GACAGGTGGTGCGTTTCAGTTTGCTGTTCCTGCCATGCGCGATACTCAGTGTAGTTCTCATTGGTGCGGGAGTGCTCCGT
TGGGCATTGTGGGGGATGAG

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 582

Protein sequence:

>583_residues
MSKKARFGVVLVVLAACSGFLFPTLQWYFLTDAQTRQRALSSREQIKEYAVQSAERDLADLTRLARAGSDEDISARYAPL
VAAARQNLSYSGRPAPSRWTAAALVSAFPVKSEQGFVLYARPLMEQTYREAVLKMKRRQAQAVKLGLDLSGGTSVVIKAD
LSEVTKGVPDAERAAIRSEAMALVLSTLENRINRFGLSEPVIRRQGEDRVYVEIPGLTDRDRVHSIVMGRGVLAFHLVDD
DATQKLLDHYRNNPQGTFDAAHQLHDLSLVPEHTSVLGVYRKDSYGLDVRDGFLVVKKEPALEGRHIRDATVSSGRANEP
LVLFDLDHEGARIFSELTTKEIGRRLAIVSDGKIRSAPAIREPITAGSGSISGFSAEEAQNLKTALRSAWLNVALEIENQ
QVVGASMGEESIRQGTRALVWGLCAVLLFMLVWYQEAGVNACVAQLLNLYIMFGVLSAFNLTLTLSSIAGMILTIGMAVD
ANVVVFERIREELALGKSRGAAVCSGFERAFWAIMDSNVTTFIAALFLSVLGTGPIKGFAYSLAIGVVSSVFTALFVSRL
MFDYGTEVLHKKTVRIGWRIARV

Sequences:

>Translated_583_residues
MSKKARFGVVLVVLAACSGFLFPTLQWYFLTDAQTRQRALSSREQIKEYAVQSAERDLADLTRLARAGSDEDISARYAPL
VAAARQNLSYSGRPAPSRWTAAALVSAFPVKSEQGFVLYARPLMEQTYREAVLKMKRRQAQAVKLGLDLSGGTSVVIKAD
LSEVTKGVPDAERAAIRSEAMALVLSTLENRINRFGLSEPVIRRQGEDRVYVEIPGLTDRDRVHSIVMGRGVLAFHLVDD
DATQKLLDHYRNNPQGTFDAAHQLHDLSLVPEHTSVLGVYRKDSYGLDVRDGFLVVKKEPALEGRHIRDATVSSGRANEP
LVLFDLDHEGARIFSELTTKEIGRRLAIVSDGKIRSAPAIREPITAGSGSISGFSAEEAQNLKTALRSAWLNVALEIENQ
QVVGASMGEESIRQGTRALVWGLCAVLLFMLVWYQEAGVNACVAQLLNLYIMFGVLSAFNLTLTLSSIAGMILTIGMAVD
ANVVVFERIREELALGKSRGAAVCSGFERAFWAIMDSNVTTFIAALFLSVLGTGPIKGFAYSLAIGVVSSVFTALFVSRL
MFDYGTEVLHKKTVRIGWRIARV
>Mature_582_residues
SKKARFGVVLVVLAACSGFLFPTLQWYFLTDAQTRQRALSSREQIKEYAVQSAERDLADLTRLARAGSDEDISARYAPLV
AAARQNLSYSGRPAPSRWTAAALVSAFPVKSEQGFVLYARPLMEQTYREAVLKMKRRQAQAVKLGLDLSGGTSVVIKADL
SEVTKGVPDAERAAIRSEAMALVLSTLENRINRFGLSEPVIRRQGEDRVYVEIPGLTDRDRVHSIVMGRGVLAFHLVDDD
ATQKLLDHYRNNPQGTFDAAHQLHDLSLVPEHTSVLGVYRKDSYGLDVRDGFLVVKKEPALEGRHIRDATVSSGRANEPL
VLFDLDHEGARIFSELTTKEIGRRLAIVSDGKIRSAPAIREPITAGSGSISGFSAEEAQNLKTALRSAWLNVALEIENQQ
VVGASMGEESIRQGTRALVWGLCAVLLFMLVWYQEAGVNACVAQLLNLYIMFGVLSAFNLTLTLSSIAGMILTIGMAVDA
NVVVFERIREELALGKSRGAAVCSGFERAFWAIMDSNVTTFIAALFLSVLGTGPIKGFAYSLAIGVVSSVFTALFVSRLM
FDYGTEVLHKKTVRIGWRIARV

Specific function: Involved in protein export

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily

Homologues:

Organism=Escherichia coli, GI1786609, Length=428, Percent_Identity=32.4766355140187, Blast_Score=209, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECD_TREPA (O83425)

Other databases:

- EMBL:   AE000520
- PIR:   H71326
- RefSeq:   NP_218850.1
- ProteinModelPortal:   O83425
- IntAct:   O83425
- GeneID:   2610862
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0410
- NMPDR:   fig|243276.1.peg.409
- TIGR:   TP_0410
- HOGENOM:   HBG354469
- OMA:   EIVETNT
- ProtClustDB:   PRK05812
- BioCyc:   TPAL243276:TP_0410-MONOMER
- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- TIGRFAMs:   TIGR00916
- TIGRFAMs:   TIGR01129

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF

EC number: NA

Molecular weight: Translated: 63861; Mature: 63730

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x20d50044)-; HASH(0x2083aac8)-; HASH(0x1f88f5b4)-; HASH(0x206468dc)-; HASH(0x1fff7554)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKARFGVVLVVLAACSGFLFPTLQWYFLTDAQTRQRALSSREQIKEYAVQSAERDLAD
CCCCHHHHHHHHHHHHHCCHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTRLARAGSDEDISARYAPLVAAARQNLSYSGRPAPSRWTAAALVSAFPVKSEQGFVLYA
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEE
RPLMEQTYREAVLKMKRRQAQAVKLGLDLSGGTSVVIKADLSEVTKGVPDAERAAIRSEA
HHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECHHHHHCCCCCHHHHHHHHHH
MALVLSTLENRINRFGLSEPVIRRQGEDRVYVEIPGLTDRDRVHSIVMGRGVLAFHLVDD
HHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECC
DATQKLLDHYRNNPQGTFDAAHQLHDLSLVPEHTSVLGVYRKDSYGLDVRDGFLVVKKEP
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHEEEEEECCCCCCCCCCCEEEEECCC
ALEGRHIRDATVSSGRANEPLVLFDLDHEGARIFSELTTKEIGRRLAIVSDGKIRSAPAI
CCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCH
REPITAGSGSISGFSAEEAQNLKTALRSAWLNVALEIENQQVVGASMGEESIRQGTRALV
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCHHHHHHHHHHHH
WGLCAVLLFMLVWYQEAGVNACVAQLLNLYIMFGVLSAFNLTLTLSSIAGMILTIGMAVD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANVVVFERIREELALGKSRGAAVCSGFERAFWAIMDSNVTTFIAALFLSVLGTGPIKGFA
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHH
YSLAIGVVSSVFTALFVSRLMFDYGTEVLHKKTVRIGWRIARV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECH
>Mature Secondary Structure 
SKKARFGVVLVVLAACSGFLFPTLQWYFLTDAQTRQRALSSREQIKEYAVQSAERDLAD
CCCHHHHHHHHHHHHHCCHHHHCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTRLARAGSDEDISARYAPLVAAARQNLSYSGRPAPSRWTAAALVSAFPVKSEQGFVLYA
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEE
RPLMEQTYREAVLKMKRRQAQAVKLGLDLSGGTSVVIKADLSEVTKGVPDAERAAIRSEA
HHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECHHHHHCCCCCHHHHHHHHHH
MALVLSTLENRINRFGLSEPVIRRQGEDRVYVEIPGLTDRDRVHSIVMGRGVLAFHLVDD
HHHHHHHHHHHHHHCCCCCHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEECC
DATQKLLDHYRNNPQGTFDAAHQLHDLSLVPEHTSVLGVYRKDSYGLDVRDGFLVVKKEP
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHEEEEEECCCCCCCCCCCEEEEECCC
ALEGRHIRDATVSSGRANEPLVLFDLDHEGARIFSELTTKEIGRRLAIVSDGKIRSAPAI
CCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCH
REPITAGSGSISGFSAEEAQNLKTALRSAWLNVALEIENQQVVGASMGEESIRQGTRALV
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCEEECCCCCHHHHHHHHHHHH
WGLCAVLLFMLVWYQEAGVNACVAQLLNLYIMFGVLSAFNLTLTLSSIAGMILTIGMAVD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANVVVFERIREELALGKSRGAAVCSGFERAFWAIMDSNVTTFIAALFLSVLGTGPIKGFA
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHH
YSLAIGVVSSVFTALFVSRLMFDYGTEVLHKKTVRIGWRIARV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876