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The map label for this gene is murI

Identifier: 189025639

GI number: 189025639

Start: 431206

End: 432012

Strand: Direct

Name: murI

Synonym: TPASS_0406

Alternate gene names: 189025639

Gene position: 431206-432012 (Clockwise)

Preceding gene: 189025636

Following gene: 189025640

Centisome position: 37.84

GC content: 53.16

Gene sequence:

>807_bases
ATGTCGGACCGACGTGAGCAATTTCAATACGCATTTTTGGATTCAGGTATAGGAGGATTGCCCTACGCACACGCCTTACG
CGTGCGTGTGCCTGAGGCCTCACTGGTGTACGTGGCGGACCGTGTATACTTTCCTTATGGGAATAAAAGTTCTGCACAGA
TTATTGCGCGTGCGTCTGCAGTTTTGCAGAAAGTGCAGACGAATTTTTCACCACACATAGTGGTACTCGCGTGTAACAGC
ATGTCTGTCAATGCACTTGAGTTTTTGCGTGCGCAGGTTTCGGTTCCAGTGGTGGGGGTGGTGCCTGCAATTAAGCAGGC
GGTGGCGTGCAGTCATAAAAAGCACATTGGTGTCTTAGCTACACAATGCACGATTACGCATCCGTACACAGCGTGTTTGA
GAGCACAGTTTGGTGCAGGGTGTGTGTTTCAGATGCGTGCGGATGCACGCCTTATTGAGTGTCTTGAGCGCGGGTTAATT
TTTGAAGTCGAAGACATGCAGCGGGAGGCAGTGGCGCGCTCAGTTATGCCCTTCCAGGAAGCGGGGGTGGATGTGCTCGT
GCTCGCGTGCACCCATTTTGTGCACGTGCGTCATCTTTTTCAGGACTGTGTTGGTACCTCGTGTACGGTGGTAGATTCGC
TAGAAGGTGTGGTACGCAGGACGTTACGTCTGTGTCCACCGCAATCTCAATTGCGTGGGAACGCCGCCTGTTACGTAACT
GGTGCGCGCGATGCAGTGTGCGCGGCACGATACGCACGGTATGCGCAGCACTTTGGATTGCGCTGGGCGGGTTTTTTGGA
CGTATGA

Upstream 100 bases:

>100_bases
ACGGGCTGGACGGGTGTGGTGTCAATGTATGCGGTGTGCAGGACCTGGGGATAACACGGTTCCTGTGAAATTTTTCAAAG
AACAGGCTAGGATGATGTCT

Downstream 100 bases:

>100_bases
ACACGGCACTGGATATCGGGTGCGTGCACTGTGTGTGTTTGTGTGGAGGCGGTAGATAAGAGAGGCTGATAGACAGCGCG
GTGCTGCGTGCGTACAATGG

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSDRREQFQYAFLDSGIGGLPYAHALRVRVPEASLVYVADRVYFPYGNKSSAQIIARASAVLQKVQTNFSPHIVVLACNS
MSVNALEFLRAQVSVPVVGVVPAIKQAVACSHKKHIGVLATQCTITHPYTACLRAQFGAGCVFQMRADARLIECLERGLI
FEVEDMQREAVARSVMPFQEAGVDVLVLACTHFVHVRHLFQDCVGTSCTVVDSLEGVVRRTLRLCPPQSQLRGNAACYVT
GARDAVCAARYARYAQHFGLRWAGFLDV

Sequences:

>Translated_268_residues
MSDRREQFQYAFLDSGIGGLPYAHALRVRVPEASLVYVADRVYFPYGNKSSAQIIARASAVLQKVQTNFSPHIVVLACNS
MSVNALEFLRAQVSVPVVGVVPAIKQAVACSHKKHIGVLATQCTITHPYTACLRAQFGAGCVFQMRADARLIECLERGLI
FEVEDMQREAVARSVMPFQEAGVDVLVLACTHFVHVRHLFQDCVGTSCTVVDSLEGVVRRTLRLCPPQSQLRGNAACYVT
GARDAVCAARYARYAQHFGLRWAGFLDV
>Mature_267_residues
SDRREQFQYAFLDSGIGGLPYAHALRVRVPEASLVYVADRVYFPYGNKSSAQIIARASAVLQKVQTNFSPHIVVLACNSM
SVNALEFLRAQVSVPVVGVVPAIKQAVACSHKKHIGVLATQCTITHPYTACLRAQFGAGCVFQMRADARLIECLERGLIF
EVEDMQREAVARSVMPFQEAGVDVLVLACTHFVHVRHLFQDCVGTSCTVVDSLEGVVRRTLRLCPPQSQLRGNAACYVTG
ARDAVCAARYARYAQHFGLRWAGFLDV

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=214, Percent_Identity=35.981308411215, Blast_Score=124, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_TREPA (O83421)

Other databases:

- EMBL:   AE000520
- PIR:   E71329
- RefSeq:   NP_218846.1
- ProteinModelPortal:   O83421
- SMR:   O83421
- GeneID:   2610846
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0406
- NMPDR:   fig|243276.1.peg.405
- TIGR:   TP_0406
- HOGENOM:   HBG731640
- OMA:   YTNINAL
- ProtClustDB:   CLSK218687
- BioCyc:   TPAL243276:TP_0406-MONOMER
- BRENDA:   5.1.1.3
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 29449; Mature: 29318

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRREQFQYAFLDSGIGGLPYAHALRVRVPEASLVYVADRVYFPYGNKSSAQIIARASA
CCCHHHHHHHHHHHCCCCCCCCHHEEEEECCCCEEEEEEEEEEECCCCCCHHHHHHHHHH
VLQKVQTNFSPHIVVLACNSMSVNALEFLRAQVSVPVVGVVPAIKQAVACSHKKHIGVLA
HHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEE
TQCTITHPYTACLRAQFGAGCVFQMRADARLIECLERGLIFEVEDMQREAVARSVMPFQE
EEEEECCHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCEEEHHHHHHHHHHHHCCCHHH
AGVDVLVLACTHFVHVRHLFQDCVGTSCTVVDSLEGVVRRTLRLCPPQSQLRGNAACYVT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEE
GARDAVCAARYARYAQHFGLRWAGFLDV
CCCHHHHHHHHHHHHHHCCCCEEEECCC
>Mature Secondary Structure 
SDRREQFQYAFLDSGIGGLPYAHALRVRVPEASLVYVADRVYFPYGNKSSAQIIARASA
CCHHHHHHHHHHHCCCCCCCCHHEEEEECCCCEEEEEEEEEEECCCCCCHHHHHHHHHH
VLQKVQTNFSPHIVVLACNSMSVNALEFLRAQVSVPVVGVVPAIKQAVACSHKKHIGVLA
HHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEE
TQCTITHPYTACLRAQFGAGCVFQMRADARLIECLERGLIFEVEDMQREAVARSVMPFQE
EEEEECCHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCEEEHHHHHHHHHHHHCCCHHH
AGVDVLVLACTHFVHVRHLFQDCVGTSCTVVDSLEGVVRRTLRLCPPQSQLRGNAACYVT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEE
GARDAVCAARYARYAQHFGLRWAGFLDV
CCCHHHHHHHHHHHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876