Click here to switch to the map view.

The map label for this gene is 189025613

Identifier: 189025613

GI number: 189025613

Start: 406441

End: 408261

Strand: Reverse

Name: 189025613

Synonym: TPASS_0380

Alternate gene names: NA

Gene position: 408261-406441 (Counterclockwise)

Preceding gene: 189025614

Following gene: 189025612

Centisome position: 35.83

GC content: 54.81

Gene sequence:

>1821_bases
GTGACTTCTGTACCAAAACCGCTTATCATCCAAGCAGACCGCTCCATTTTACTTGATGTGCACGCTCCTGAGGCGGTAGC
AGCACGCAAGGCGCTCGTTTCCTTTGCAGAACTGGAAAAATCTCCAGAGCATCTACACAGCTACCGACTCACTCCTCTTT
CTCTGTGGAACGCCGCGAGCGCAGGATTCAGCCCCCAGATGATTGCACAAACACTGACGCGTTTCTCACGCTTCACTCCC
CCGCAAACAGTACTCGACTGGGTAGTGGATATCATGAGCCGCTATGGCAAAATTCGCCTTCGCGAGGATACGACGCACAG
CACCCTACTGCGCCTTCAGGTACGCGACGCACACATCGCAAGAGAAATTGCCGCCTCAAAAAGTCTTGCATCGCACCTTT
CCCCCACAACCGCTTGCCTGCAGGACGGTCCGCTGCCCACACCGGACACTGCGCGCATTGCCCAGCCGGATACGACACCT
CAGGTGCAGGGTGCACAGACTGGATGCAGTTACGACTTTCTATTGCCACGCCTCCACCGAGGCACCGTTAAACAATTACT
CTTGCGCCACGGATGGCCGGTGCATGATGAAGTGCCTCTCCGCGAGGGAACTCCCCTATCCTTGCGCTTACGCATCTCTC
CGGCTTCGTGTCCTCCTCCTTCTACTGCGTATCCGTGTTGTCACACGCCAGGGACACCCTCGTTTGTGCCACGTGACTAC
CAGTGGGAAGCAGCCGATGCCTTCGTCGGGAATCGCACACAAGGGAGCGGATTTGGTGTGGTAGTTTTGCCGTGTGGCGC
GGGAAAAACGGTTGTCGGTTTACTCGTTATGGGTCTGTTGCAAACGGATACCCTGATTCTGACTCCTAATAGCGCAGCTG
CACAGCAATGGAAACGTGAATTGTGTGAAAAAACCGACCTGGACGGGACATCCATCGGTATCTATTCAGGAGAATGCAAG
GAAATCAGACCAGTGACTATCGCAACCTACCAGATACTCACCTGGCGTGCGCATGCAGACGCTCCCTTTTCCCATTTCCG
TCTCTTTATGGAACGCAGTTGGGGTTTGATTATTTACGATGAGGTGCACTTGCTCCCTGCACCGCTTTTCCGTATCACCG
CAGAACTTCAGGTGGTACGACGCTTGGGATTAACTGCAACGCTCGTGCGAGAAGATGGCTGTGCGCAGGATGTGTTCAGC
CTCGTAGGACCGAAGCGGTATGACGTGCCGTGGAAGGATTTAGAAGCACGCGGCTGGATCGCACGGGTGCGGTGCGTAGA
AGTTCGGGTAACGATGGACCGGTCACTCCAGTACCAGTACATGACAGCTCCTGTGCGCCTGCGACATCGCCTTGCCAGCG
AGAACGAAGCAAAAGTAGCGGTGGTACAGCGTCTATTGCGCGCACATGCAGGTGCGCCTACACTGATTATTGGGCAATAC
GTGCAGCAGTTATTACATCTCGCACACGTACTGCAGGTGCCACTGGTGAGCGGAAGACAAACTTATGCGGCGCGTGAAGC
CATCTATCAGCGTTTTCGCGAGGGCACGCTCCAGGTGCTCGTTGTATCAAAGGTGGCAAATTGTGCGCTTGATCTTCCTG
ACGCGTCGGTTGCAATTCAAGTTTCCGGGACATTTGGCAGCCGTCAGGAGGAGGCGCAACGCCTCGGACGCCTCTTACGG
CCAAAGATATGCGACGCCCATTTTTACTCGTTAGTTACAGAACAAACGGTGGAAGAAGACTGTGCACTGCGTCGCCAGCG
GTTTTTGGTAGAGCAGGGTTACACGTACGAAACCCTTCGCGTAAGCGAAGTACACGAATAA

Upstream 100 bases:

>100_bases
CAGAGGGCACGCGTGCCGTTGGGACATCGTGGTGGAGTTGCAGCGCGCTTGCGTCACACGGCCTTACTCCGCGGTCAACG
CGAACGTATAATGGTGCGCT

Downstream 100 bases:

>100_bases
AGGATACTCCGTGCAGAGTCCTCCCTGTGTGTGTGAGGGGGGGGGGAGGAGGGGGTGACCGTGCGGTCTCCCTTGTTTTT
TTGGTTCAAGACCGCTACAG

Product: DNA repair helicase

Products: NA

Alternate protein names: DNA Repair Helicase; Type III Restriction Res Subunit; Helicase Domain Protein; ATP-Dependent DNA Helicase; DNA Repair Helicase RAD; Helicase Domain-Containing Protein; DNA Repair Helicase Rad; Superfamily II DNA/RNA Helicase; DNA/RNA Helicase; Type III Restriction Res Subunit Family; Helicase; DNA Helicase; DNA Repair Protein Rad; DNA Repair Protein; DNA/RNA Helicase Superfamily II; DNA Repair Protein RAD; Helicase-Like Protein; Helicase Protein; ATP-Dependent Helicase; DNA Or RNA Helicase Of Superfamily II; Helicase ATP-Dependent; Helicase DNA Repair; DNA Or RNA Helicase; Helicase DNA Repair Rad; RAD25-Type DNA Repair Helicase; Restriction Endonuclease Family Protein; XPB/RAD25-Related Helicase; DEAD/DEAH Box Helicase-Like; DNA-Helicase; DNA Or RNA Helicase Of Superfamily Protein II

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MTSVPKPLIIQADRSILLDVHAPEAVAARKALVSFAELEKSPEHLHSYRLTPLSLWNAASAGFSPQMIAQTLTRFSRFTP
PQTVLDWVVDIMSRYGKIRLREDTTHSTLLRLQVRDAHIAREIAASKSLASHLSPTTACLQDGPLPTPDTARIAQPDTTP
QVQGAQTGCSYDFLLPRLHRGTVKQLLLRHGWPVHDEVPLREGTPLSLRLRISPASCPPPSTAYPCCHTPGTPSFVPRDY
QWEAADAFVGNRTQGSGFGVVVLPCGAGKTVVGLLVMGLLQTDTLILTPNSAAAQQWKRELCEKTDLDGTSIGIYSGECK
EIRPVTIATYQILTWRAHADAPFSHFRLFMERSWGLIIYDEVHLLPAPLFRITAELQVVRRLGLTATLVREDGCAQDVFS
LVGPKRYDVPWKDLEARGWIARVRCVEVRVTMDRSLQYQYMTAPVRLRHRLASENEAKVAVVQRLLRAHAGAPTLIIGQY
VQQLLHLAHVLQVPLVSGRQTYAAREAIYQRFREGTLQVLVVSKVANCALDLPDASVAIQVSGTFGSRQEEAQRLGRLLR
PKICDAHFYSLVTEQTVEEDCALRRQRFLVEQGYTYETLRVSEVHE

Sequences:

>Translated_606_residues
MTSVPKPLIIQADRSILLDVHAPEAVAARKALVSFAELEKSPEHLHSYRLTPLSLWNAASAGFSPQMIAQTLTRFSRFTP
PQTVLDWVVDIMSRYGKIRLREDTTHSTLLRLQVRDAHIAREIAASKSLASHLSPTTACLQDGPLPTPDTARIAQPDTTP
QVQGAQTGCSYDFLLPRLHRGTVKQLLLRHGWPVHDEVPLREGTPLSLRLRISPASCPPPSTAYPCCHTPGTPSFVPRDY
QWEAADAFVGNRTQGSGFGVVVLPCGAGKTVVGLLVMGLLQTDTLILTPNSAAAQQWKRELCEKTDLDGTSIGIYSGECK
EIRPVTIATYQILTWRAHADAPFSHFRLFMERSWGLIIYDEVHLLPAPLFRITAELQVVRRLGLTATLVREDGCAQDVFS
LVGPKRYDVPWKDLEARGWIARVRCVEVRVTMDRSLQYQYMTAPVRLRHRLASENEAKVAVVQRLLRAHAGAPTLIIGQY
VQQLLHLAHVLQVPLVSGRQTYAAREAIYQRFREGTLQVLVVSKVANCALDLPDASVAIQVSGTFGSRQEEAQRLGRLLR
PKICDAHFYSLVTEQTVEEDCALRRQRFLVEQGYTYETLRVSEVHE
>Mature_605_residues
TSVPKPLIIQADRSILLDVHAPEAVAARKALVSFAELEKSPEHLHSYRLTPLSLWNAASAGFSPQMIAQTLTRFSRFTPP
QTVLDWVVDIMSRYGKIRLREDTTHSTLLRLQVRDAHIAREIAASKSLASHLSPTTACLQDGPLPTPDTARIAQPDTTPQ
VQGAQTGCSYDFLLPRLHRGTVKQLLLRHGWPVHDEVPLREGTPLSLRLRISPASCPPPSTAYPCCHTPGTPSFVPRDYQ
WEAADAFVGNRTQGSGFGVVVLPCGAGKTVVGLLVMGLLQTDTLILTPNSAAAQQWKRELCEKTDLDGTSIGIYSGECKE
IRPVTIATYQILTWRAHADAPFSHFRLFMERSWGLIIYDEVHLLPAPLFRITAELQVVRRLGLTATLVREDGCAQDVFSL
VGPKRYDVPWKDLEARGWIARVRCVEVRVTMDRSLQYQYMTAPVRLRHRLASENEAKVAVVQRLLRAHAGAPTLIIGQYV
QQLLHLAHVLQVPLVSGRQTYAAREAIYQRFREGTLQVLVVSKVANCALDLPDASVAIQVSGTFGSRQEEAQRLGRLLRP
KICDAHFYSLVTEQTVEEDCALRRQRFLVEQGYTYETLRVSEVHE

Specific function: Unknown

COG id: COG1061

COG function: function code KL; DNA or RNA helicases of superfamily II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557563, Length=643, Percent_Identity=29.5489891135303, Blast_Score=240, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17556358, Length=387, Percent_Identity=35.1421188630491, Blast_Score=217, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6322048, Length=632, Percent_Identity=29.1139240506329, Blast_Score=243, Evalue=6e-65,
Organism=Drosophila melanogaster, GI221331068, Length=399, Percent_Identity=35.0877192982456, Blast_Score=227, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24662247, Length=399, Percent_Identity=35.0877192982456, Blast_Score=227, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 67599; Mature: 67467

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVPKPLIIQADRSILLDVHAPEAVAARKALVSFAELEKSPEHLHSYRLTPLSLWNAAS
CCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHCCCC
AGFSPQMIAQTLTRFSRFTPPQTVLDWVVDIMSRYGKIRLREDTTHSTLLRLQVRDAHIA
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEHHHHHH
REIAASKSLASHLSPTTACLQDGPLPTPDTARIAQPDTTPQVQGAQTGCSYDFLLPRLHR
HHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
GTVKQLLLRHGWPVHDEVPLREGTPLSLRLRISPASCPPPSTAYPCCHTPGTPSFVPRDY
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
QWEAADAFVGNRTQGSGFGVVVLPCGAGKTVVGLLVMGLLQTDTLILTPNSAAAQQWKRE
CCCHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHH
LCEKTDLDGTSIGIYSGECKEIRPVTIATYQILTWRAHADAPFSHFRLFMERSWGLIIYD
HHHHCCCCCCEEEEECCCCCCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEE
EVHLLPAPLFRITAELQVVRRLGLTATLVREDGCAQDVFSLVGPKRYDVPWKDLEARGWI
CCHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCCCCCCHHHCCCCCE
ARVRCVEVRVTMDRSLQYQYMTAPVRLRHRLASENEAKVAVVQRLLRAHAGAPTLIIGQY
EEEEEEEEEEEECCCCEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
VQQLLHLAHVLQVPLVSGRQTYAAREAIYQRFREGTLQVLVVSKVANCALDLPDASVAIQ
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHEECCCCCEEEEE
VSGTFGSRQEEAQRLGRLLRPKICDAHFYSLVTEQTVEEDCALRRQRFLVEQGYTYETLR
EECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
VSEVHE
ECCCCC
>Mature Secondary Structure 
TSVPKPLIIQADRSILLDVHAPEAVAARKALVSFAELEKSPEHLHSYRLTPLSLWNAAS
CCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHCCCC
AGFSPQMIAQTLTRFSRFTPPQTVLDWVVDIMSRYGKIRLREDTTHSTLLRLQVRDAHIA
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEHHHHHH
REIAASKSLASHLSPTTACLQDGPLPTPDTARIAQPDTTPQVQGAQTGCSYDFLLPRLHR
HHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
GTVKQLLLRHGWPVHDEVPLREGTPLSLRLRISPASCPPPSTAYPCCHTPGTPSFVPRDY
HHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
QWEAADAFVGNRTQGSGFGVVVLPCGAGKTVVGLLVMGLLQTDTLILTPNSAAAQQWKRE
CCCHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHH
LCEKTDLDGTSIGIYSGECKEIRPVTIATYQILTWRAHADAPFSHFRLFMERSWGLIIYD
HHHHCCCCCCEEEEECCCCCCCCCEEEEEEEEEEEEECCCCCHHHHHHHHHCCCCEEEEE
EVHLLPAPLFRITAELQVVRRLGLTATLVREDGCAQDVFSLVGPKRYDVPWKDLEARGWI
CCHHCCCHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCCCCCCHHHCCCCCE
ARVRCVEVRVTMDRSLQYQYMTAPVRLRHRLASENEAKVAVVQRLLRAHAGAPTLIIGQY
EEEEEEEEEEEECCCCEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
VQQLLHLAHVLQVPLVSGRQTYAAREAIYQRFREGTLQVLVVSKVANCALDLPDASVAIQ
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHEECCCCCEEEEE
VSGTFGSRQEEAQRLGRLLRPKICDAHFYSLVTEQTVEEDCALRRQRFLVEQGYTYETLR
EECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
VSEVHE
ECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA