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The map label for this gene is coaE

Identifier: 189025530

GI number: 189025530

Start: 310770

End: 311405

Strand: Direct

Name: coaE

Synonym: TPASS_0296

Alternate gene names: 189025530

Gene position: 310770-311405 (Clockwise)

Preceding gene: 189025529

Following gene: 189025531

Centisome position: 27.27

GC content: 51.89

Gene sequence:

>636_bases
GTGCGCGAGTTTTGTCCACTAATTGGTGTCATCGGTCGAAGTGGTGCGGGGAAGAATGTGGTCTCGCGCCTGCTTGCAGA
ACGGGGATGTTACTGTATTGACGCGGATGCGCGCACGCGTGAACTTTTGGAATCTTATGGCGACTCTATAGTAGAGCGGT
TTCAAGTGGCTGCGGCTGCGCGCGGCCTTTCGTTACGGCGTAAAGATGGCGGCCTGCACTCTGCGCATTTGGGTGTGTTA
CTGTTCTCTGAGCCTAAACTACTGCAGCAGCACGAAGAGTTTTTGTTACCGAAAGTTACCCGTCTTTTGTGTGAAGACAT
AGCGCGCGCGCAGGCTGCGCGTCCAAAAGCGATAGTACTGAATGCGCCGACATTGCATAAAACAGAACTGTTACAAGCCT
GTAGTTTTGTTTTGTACATATGGGCGCCAAGCATACTGCGCATGTGGCGATGTAAGAAACGGGAACGAGTATCTTTTACT
CACCTTTTACGCAGGTTTTCTGCGCAGAAGGGTTTCTATGCTCAAAGCATCGCGCAAAACGCCGATACCTACACGGTGGC
CAACTGTGGGCGTGTTGCGTCATTGGCGCGAAAAGTCGATTGCATTCTGACGCGCAGGGGTGTTTTAGGCGAGTAA

Upstream 100 bases:

>100_bases
GAGGCACAGGGGTAGTCAGCGCAAGATACGCAGGAATATCGGGTGTTCAGCACATTCTGAACACTTGAGGACGGTGCGTG
TTTGACGTTACGCTCTCGCT

Downstream 100 bases:

>100_bases
ATATGGAACAGAAGAGAATTTTGTGGATTGTCATCTCCCTGAGTGTGTTTATGCTCATTATTTTTGGCGTCGCGCTTTTG
TTGTACTCTCCTACCTATTC

Product: hypothetical protein

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MREFCPLIGVIGRSGAGKNVVSRLLAERGCYCIDADARTRELLESYGDSIVERFQVAAAARGLSLRRKDGGLHSAHLGVL
LFSEPKLLQQHEEFLLPKVTRLLCEDIARAQAARPKAIVLNAPTLHKTELLQACSFVLYIWAPSILRMWRCKKRERVSFT
HLLRRFSAQKGFYAQSIAQNADTYTVANCGRVASLARKVDCILTRRGVLGE

Sequences:

>Translated_211_residues
MREFCPLIGVIGRSGAGKNVVSRLLAERGCYCIDADARTRELLESYGDSIVERFQVAAAARGLSLRRKDGGLHSAHLGVL
LFSEPKLLQQHEEFLLPKVTRLLCEDIARAQAARPKAIVLNAPTLHKTELLQACSFVLYIWAPSILRMWRCKKRERVSFT
HLLRRFSAQKGFYAQSIAQNADTYTVANCGRVASLARKVDCILTRRGVLGE
>Mature_211_residues
MREFCPLIGVIGRSGAGKNVVSRLLAERGCYCIDADARTRELLESYGDSIVERFQVAAAARGLSLRRKDGGLHSAHLGVL
LFSEPKLLQQHEEFLLPKVTRLLCEDIARAQAARPKAIVLNAPTLHKTELLQACSFVLYIWAPSILRMWRCKKRERVSFT
HLLRRFSAQKGFYAQSIAQNADTYTVANCGRVASLARKVDCILTRRGVLGE

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_TREPA (O83319)

Other databases:

- EMBL:   AE000520
- PIR:   B71341
- RefSeq:   NP_218737.1
- ProteinModelPortal:   O83319
- IntAct:   O83319
- GeneID:   2611190
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0296
- NMPDR:   fig|243276.1.peg.296
- TIGR:   TP_0296
- HOGENOM:   HBG731960
- OMA:   NEITHPI
- ProtClustDB:   CLSK218632
- BioCyc:   TPAL243276:TP_0296-MONOMER
- BRENDA:   2.7.1.24
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 23584; Mature: 23584

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS51219 DPCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREFCPLIGVIGRSGAGKNVVSRLLAERGCYCIDADARTRELLESYGDSIVERFQVAAAA
CCCHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RGLSLRRKDGGLHSAHLGVLLFSEPKLLQQHEEFLLPKVTRLLCEDIARAQAARPKAIVL
HCCHHCCCCCCCCHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
NAPTLHKTELLQACSFVLYIWAPSILRMWRCKKRERVSFTHLLRRFSAQKGFYAQSIAQN
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
ADTYTVANCGRVASLARKVDCILTRRGVLGE
CCCEEHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MREFCPLIGVIGRSGAGKNVVSRLLAERGCYCIDADARTRELLESYGDSIVERFQVAAAA
CCCHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RGLSLRRKDGGLHSAHLGVLLFSEPKLLQQHEEFLLPKVTRLLCEDIARAQAARPKAIVL
HCCHHCCCCCCCCHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
NAPTLHKTELLQACSFVLYIWAPSILRMWRCKKRERVSFTHLLRRFSAQKGFYAQSIAQN
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
ADTYTVANCGRVASLARKVDCILTRRGVLGE
CCCEEHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876