Click here to switch to the map view.

The map label for this gene is nusG

Identifier: 189025469

GI number: 189025469

Start: 243682

End: 244239

Strand: Direct

Name: nusG

Synonym: TPASS_0236

Alternate gene names: 189025469

Gene position: 243682-244239 (Clockwise)

Preceding gene: 189025468

Following gene: 189025470

Centisome position: 21.39

GC content: 52.87

Gene sequence:

>558_bases
ATGGCGAAAGAGTGGTATATTCTGCACACATTCTCGGGTCGCGAGGCAAGGGTGGAGCGGGCTGTCCGTATGCTCGTGGA
GCATGCGAGGATTCCAACGAACGTTATCTTTGATATAAAAATCCCTGAGGAACTGCTTACCGAGGTGAAAGATGGTAAGA
AGAGGGTGGTTAGGCGTAAGTTTTTCCCTGGTTACTTGTTGGTGGAAATGGATTTGCCCGAGGTTGACTGGAGGATAGTG
TGTAACGAGGTGCGCAGGATTCCTGGTGTTTCCGGTTTTTTGGGTTCTTCGGGCAATGCGAAGCCTCAGGCGGTTTCTGC
GGATGAAGCTCGGCGTATTTTGCAGAAGGCGGGGGAAATTAAGGGGGATAGGACTCCTCGTATCGCTCAGACTTTTTTGG
TTGGACAACAGGTGAGGATCGTTGAGGGGCCGTTTGCTACTTTCTCGGGTGAGGTGGAGGAGGTGATGAGTGAACGCAAC
AAGGTGCGTGTGGCAGTCACCATCTTTGGCCGCGCTACTCCTGTGGAGTTGGAGCTAGTCCAGGTGGAGGCGCTCTGA

Upstream 100 bases:

>100_bases
TAAGGTAGTGCTCGTCTCTACCGTTGTCATGGCGCTTTTCCTCGGGCTTATCGATGCTCTGTTCGTGGCGTTGCTGAGTT
TCTTCTTCTGAGGGGATAGA

Downstream 100 bases:

>100_bases
TTTTCTTCTTCCAGGGTGGAGAGTGTTGCAATGCGCATGATTGCCTGCCGCTTACGCGTTGGTTTCGGGTGTTTTGTTGT
TTTTTACGTCATAAGGAGAG

Product: transcription antitermination protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MAKEWYILHTFSGREARVERAVRMLVEHARIPTNVIFDIKIPEELLTEVKDGKKRVVRRKFFPGYLLVEMDLPEVDWRIV
CNEVRRIPGVSGFLGSSGNAKPQAVSADEARRILQKAGEIKGDRTPRIAQTFLVGQQVRIVEGPFATFSGEVEEVMSERN
KVRVAVTIFGRATPVELELVQVEAL

Sequences:

>Translated_185_residues
MAKEWYILHTFSGREARVERAVRMLVEHARIPTNVIFDIKIPEELLTEVKDGKKRVVRRKFFPGYLLVEMDLPEVDWRIV
CNEVRRIPGVSGFLGSSGNAKPQAVSADEARRILQKAGEIKGDRTPRIAQTFLVGQQVRIVEGPFATFSGEVEEVMSERN
KVRVAVTIFGRATPVELELVQVEAL
>Mature_184_residues
AKEWYILHTFSGREARVERAVRMLVEHARIPTNVIFDIKIPEELLTEVKDGKKRVVRRKFFPGYLLVEMDLPEVDWRIVC
NEVRRIPGVSGFLGSSGNAKPQAVSADEARRILQKAGEIKGDRTPRIAQTFLVGQQVRIVEGPFATFSGEVEEVMSERNK
VRVAVTIFGRATPVELELVQVEAL

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain

Homologues:

Organism=Escherichia coli, GI1790414, Length=183, Percent_Identity=39.8907103825137, Blast_Score=133, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUSG_TREPA (O83264)

Other databases:

- EMBL:   AE000520
- PIR:   F71349
- RefSeq:   NP_218676.1
- ProteinModelPortal:   O83264
- SMR:   O83264
- IntAct:   O83264
- MINT:   MINT-6481297
- GeneID:   2611480
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0236
- NMPDR:   fig|243276.1.peg.235
- TIGR:   TP_0236
- HOGENOM:   HBG751162
- OMA:   VASGCEK
- ProtClustDB:   CLSK218604
- BioCyc:   TPAL243276:TP_0236-MONOMER
- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.30.30.30
- Gene3D:   G3DSA:3.30.70.940
- PRINTS:   PR00338
- SMART:   SM00739
- SMART:   SM00738
- TIGRFAMs:   TIGR00922

Pfam domain/function: PF00467 KOW; PF02357 NusG; SSF82679 Transcrpt_antiterm_NusG_N; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20929; Mature: 20797

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEWYILHTFSGREARVERAVRMLVEHARIPTNVIFDIKIPEELLTEVKDGKKRVVRRK
CCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCHHHHHHHHH
FFPGYLLVEMDLPEVDWRIVCNEVRRIPGVSGFLGSSGNAKPQAVSADEARRILQKAGEI
CCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
KGDRTPRIAQTFLVGQQVRIVEGPFATFSGEVEEVMSERNKVRVAVTIFGRATPVELELV
CCCCCCHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEEECCCCCEEEEEE
QVEAL
EEECC
>Mature Secondary Structure 
AKEWYILHTFSGREARVERAVRMLVEHARIPTNVIFDIKIPEELLTEVKDGKKRVVRRK
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCHHHHHHHHH
FFPGYLLVEMDLPEVDWRIVCNEVRRIPGVSGFLGSSGNAKPQAVSADEARRILQKAGEI
CCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
KGDRTPRIAQTFLVGQQVRIVEGPFATFSGEVEEVMSERNKVRVAVTIFGRATPVELELV
CCCCCCHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEEECCCCCEEEEEE
QVEAL
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876