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The map label for this gene is betT [H]

Identifier: 189025340

GI number: 189025340

Start: 118828

End: 120360

Strand: Reverse

Name: betT [H]

Synonym: TPASS_0106

Alternate gene names: 189025340

Gene position: 120360-118828 (Counterclockwise)

Preceding gene: 189025341

Following gene: 189025336

Centisome position: 10.56

GC content: 49.18

Gene sequence:

>1533_bases
ATGCAGAAAGAAAAATGTGACTTCAGCGTCTCTCTCATCCCATTGGGAATCGTGATCTCGTGCGCACTCCTATTTATTTC
CTTTCCTGACATTTCTCATCGGGTAATCGGTACCCTCTTGAATATACTGGTAAACAAACTGGGCTTTTTCTATATCCTTA
CCGGACTGTTTTTTTTAGGAACGACGCTGACTATTGCTTTTTCACGGTATGGTGCGGTGTATCTGGGTACTACGCGCACC
GCACGCTATTCCAACTTTACGTGGGGCTCCATGATTTTTACGTCCACCATGGCGGCGGATATTTTGTATTGGTCGCTCAT
CGAATGGGCGCACTACTTCACTCAAGCTCCGTTTATAGCAGAACACTCCCCTCCCACGGAAAGACAAGAATGGGCGGCAG
CGTATCCCCTTTTCCATTGGGGCATCATACCTTGGTCTTTTTACGTTCTTCTCGCAGTGGCCTTCGGCTACATGTTGCAT
GTAAAGAAGCGACACACACACAAAATTTCTGAAGCCTGTCGTCCGCTGCTGGGCGCGTACGTAGACGGAATAATAGGAGA
AGCAATCGATATCTGTTCTGTAGTGGGATTGCTTCTAGGCGTTGCAACCACGTTTTCCTTAGCAACGCCCCTCCTTTCGC
TCATGGTTTCTCTCTTGTTCGGTATTTCTAACACCCAGCTGCTCGCTTTAGCGTTGCTCTGCGTTATTGCGTTGGTGTAC
ACCACAGCAGTACTGCTGGGTACCCAGGGGATCTCAAAGCTCTCGCGTGCCGCGGTGTACTGCTTTAGTACCGTTCTTGT
TTTCTTCTTGTGTGCAGGACCAACCGTGTATCTTATCGAGACGGGTATCACCGCGATAGGGAAAATGCTACAAAACTTCT
TTCTTATGGCAACGTGGATGGATCCTTCTCGTATTTCATTACAGGAAACGGATGGGACGCTTGGATTTCCACAGCGGTGG
ACTATCTTTTACTGGGCGTATTGGATCACGTGGTCTGTTGCAACCCCATTCTTCATCGGCGCGATATCCGAAGGGAGAAC
CATCCGGAATACCATCGTCGGAGGGCTCTGCTGGGGTATCGCAGGTACGTACGGCTCCTTCATCGTCTTAGGGAACTACG
GGCTCTATTTACAAACGCACCACCTCCTTCCTGCCGCGTACTTCGTGCGCGCGGGGAATACACCCGCTGAGGTGATTATC
GCAATTATTCAGACACTGCCCTGCGCGTACATCGTTATGGCGCTGTTGGCAGCTACCATGATCGCCTTTTATGCAAGTAC
TTTTGACGCATTAACGCTCATCATCGCTTCCTATTCGCAAAAAAGCGTTGCACCGGGAGAAGAACCACGTCAAATAATGA
AATCGTTTTGGGCGGTTGCGTGCATTCTCCTTCCCGCTTCTCTCATATTCTCCCAGTCCACACTCATGCACCTGAAAAGT
TTAGCCATCATTGCGGCATTTCCTTTAGCGCTGATTATGTTGTGCGTGGTAGCATCATTTTTTAAGGAACTACGCGCCGA
GGTAACCTCATAA

Upstream 100 bases:

>100_bases
CTTGGTATCTCGTTTGGAGATTATGGACTGAAAATGTACCGATATGCAAAAGAATATTACGAAGCAGTTCAGACGCTCCT
GAAAACACATAGGGCAGATC

Downstream 100 bases:

>100_bases
CGTGCCCTGTTGCATCCCTCAGATGGGTATGCTAATGAAAATCACCCCAACTATTTCCAGACTCCACGTGTATACGCAGC
GGGATCGAGAGCTCAACAGC

Product: carnitine transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MQKEKCDFSVSLIPLGIVISCALLFISFPDISHRVIGTLLNILVNKLGFFYILTGLFFLGTTLTIAFSRYGAVYLGTTRT
ARYSNFTWGSMIFTSTMAADILYWSLIEWAHYFTQAPFIAEHSPPTERQEWAAAYPLFHWGIIPWSFYVLLAVAFGYMLH
VKKRHTHKISEACRPLLGAYVDGIIGEAIDICSVVGLLLGVATTFSLATPLLSLMVSLLFGISNTQLLALALLCVIALVY
TTAVLLGTQGISKLSRAAVYCFSTVLVFFLCAGPTVYLIETGITAIGKMLQNFFLMATWMDPSRISLQETDGTLGFPQRW
TIFYWAYWITWSVATPFFIGAISEGRTIRNTIVGGLCWGIAGTYGSFIVLGNYGLYLQTHHLLPAAYFVRAGNTPAEVII
AIIQTLPCAYIVMALLAATMIAFYASTFDALTLIIASYSQKSVAPGEEPRQIMKSFWAVACILLPASLIFSQSTLMHLKS
LAIIAAFPLALIMLCVVASFFKELRAEVTS

Sequences:

>Translated_510_residues
MQKEKCDFSVSLIPLGIVISCALLFISFPDISHRVIGTLLNILVNKLGFFYILTGLFFLGTTLTIAFSRYGAVYLGTTRT
ARYSNFTWGSMIFTSTMAADILYWSLIEWAHYFTQAPFIAEHSPPTERQEWAAAYPLFHWGIIPWSFYVLLAVAFGYMLH
VKKRHTHKISEACRPLLGAYVDGIIGEAIDICSVVGLLLGVATTFSLATPLLSLMVSLLFGISNTQLLALALLCVIALVY
TTAVLLGTQGISKLSRAAVYCFSTVLVFFLCAGPTVYLIETGITAIGKMLQNFFLMATWMDPSRISLQETDGTLGFPQRW
TIFYWAYWITWSVATPFFIGAISEGRTIRNTIVGGLCWGIAGTYGSFIVLGNYGLYLQTHHLLPAAYFVRAGNTPAEVII
AIIQTLPCAYIVMALLAATMIAFYASTFDALTLIIASYSQKSVAPGEEPRQIMKSFWAVACILLPASLIFSQSTLMHLKS
LAIIAAFPLALIMLCVVASFFKELRAEVTS
>Mature_510_residues
MQKEKCDFSVSLIPLGIVISCALLFISFPDISHRVIGTLLNILVNKLGFFYILTGLFFLGTTLTIAFSRYGAVYLGTTRT
ARYSNFTWGSMIFTSTMAADILYWSLIEWAHYFTQAPFIAEHSPPTERQEWAAAYPLFHWGIIPWSFYVLLAVAFGYMLH
VKKRHTHKISEACRPLLGAYVDGIIGEAIDICSVVGLLLGVATTFSLATPLLSLMVSLLFGISNTQLLALALLCVIALVY
TTAVLLGTQGISKLSRAAVYCFSTVLVFFLCAGPTVYLIETGITAIGKMLQNFFLMATWMDPSRISLQETDGTLGFPQRW
TIFYWAYWITWSVATPFFIGAISEGRTIRNTIVGGLCWGIAGTYGSFIVLGNYGLYLQTHHLLPAAYFVRAGNTPAEVII
AIIQTLPCAYIVMALLAATMIAFYASTFDALTLIIASYSQKSVAPGEEPRQIMKSFWAVACILLPASLIFSQSTLMHLKS
LAIIAAFPLALIMLCVVASFFKELRAEVTS

Specific function: High-affinity uptake of choline driven by a proton- motive force [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=508, Percent_Identity=26.5748031496063, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1788102, Length=455, Percent_Identity=25.2747252747253, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1786224, Length=515, Percent_Identity=26.7961165048544, Blast_Score=155, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 56168; Mature: 56168

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKEKCDFSVSLIPLGIVISCALLFISFPDISHRVIGTLLNILVNKLGFFYILTGLFFLG
CCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTLTIAFSRYGAVYLGTTRTARYSNFTWGSMIFTSTMAADILYWSLIEWAHYFTQAPFIA
HHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EHSPPTERQEWAAAYPLFHWGIIPWSFYVLLAVAFGYMLHVKKRHTHKISEACRPLLGAY
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDGIIGEAIDICSVVGLLLGVATTFSLATPLLSLMVSLLFGISNTQLLALALLCVIALVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TTAVLLGTQGISKLSRAAVYCFSTVLVFFLCAGPTVYLIETGITAIGKMLQNFFLMATWM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHEEC
DPSRISLQETDGTLGFPQRWTIFYWAYWITWSVATPFFIGAISEGRTIRNTIVGGLCWGI
CCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AGTYGSFIVLGNYGLYLQTHHLLPAAYFVRAGNTPAEVIIAIIQTLPCAYIVMALLAATM
HHCCCCEEEEECCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
IAFYASTFDALTLIIASYSQKSVAPGEEPRQIMKSFWAVACILLPASLIFSQSTLMHLKS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIIAAFPLALIMLCVVASFFKELRAEVTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKEKCDFSVSLIPLGIVISCALLFISFPDISHRVIGTLLNILVNKLGFFYILTGLFFLG
CCCCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTLTIAFSRYGAVYLGTTRTARYSNFTWGSMIFTSTMAADILYWSLIEWAHYFTQAPFIA
HHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EHSPPTERQEWAAAYPLFHWGIIPWSFYVLLAVAFGYMLHVKKRHTHKISEACRPLLGAY
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDGIIGEAIDICSVVGLLLGVATTFSLATPLLSLMVSLLFGISNTQLLALALLCVIALVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
TTAVLLGTQGISKLSRAAVYCFSTVLVFFLCAGPTVYLIETGITAIGKMLQNFFLMATWM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHEEC
DPSRISLQETDGTLGFPQRWTIFYWAYWITWSVATPFFIGAISEGRTIRNTIVGGLCWGI
CCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AGTYGSFIVLGNYGLYLQTHHLLPAAYFVRAGNTPAEVIIAIIQTLPCAYIVMALLAATM
HHCCCCEEEEECCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
IAFYASTFDALTLIIASYSQKSVAPGEEPRQIMKSFWAVACILLPASLIFSQSTLMHLKS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAIIAAFPLALIMLCVVASFFKELRAEVTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]