Definition Treponema pallidum subsp. pallidum SS14, complete genome.
Accession NC_010741
Length 1,139,457

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The map label for this gene is infA

Identifier: 189025331

GI number: 189025331

Start: 106438

End: 106656

Strand: Direct

Name: infA

Synonym: TPASS_0097

Alternate gene names: 189025331

Gene position: 106438-106656 (Clockwise)

Preceding gene: 189025329

Following gene: 189025334

Centisome position: 9.34

GC content: 54.79

Gene sequence:

>219_bases
GTGACGAAAGAAGAAGCAATCGAGGTGGACGGAGTGGTTAAGGAAGCGCTGCCGAACACCACCTTTAGAGTGCAATTGCA
GAATGGGCACGAGATCCTTGCGTATCTTTCAGGTCGGATGCGCAAGCACTACATCCGTATCGTGCCCGGAGACTCGGTGA
AGGTCGCGCTCTCACCCTACGACCTCTCCCGCGGCAGAATTATGTTTCGTGAGCGTTAG

Upstream 100 bases:

>100_bases
CGTAGACTGCTGGARGGACCGCTCCGTCCATTATACGGACGATGGAGGGAAAAGGCAATGTTCTGCCCGGCAGGTTGCGT
CCGGTGCACGTGGAGGGTCA

Downstream 100 bases:

>100_bases
ATTCCTCTCTCGCAGGAGAGAGGTGCTTGCTCCTCTTTAGCAGCGGGGTTGCTCATCCTTCAAGGAGGATTGAGAGTCCT
GCCCTCAGGGTGTGCACTCC

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 72; Mature: 71

Protein sequence:

>72_residues
MTKEEAIEVDGVVKEALPNTTFRVQLQNGHEILAYLSGRMRKHYIRIVPGDSVKVALSPYDLSRGRIMFRER

Sequences:

>Translated_72_residues
MTKEEAIEVDGVVKEALPNTTFRVQLQNGHEILAYLSGRMRKHYIRIVPGDSVKVALSPYDLSRGRIMFRER
>Mature_71_residues
TKEEAIEVDGVVKEALPNTTFRVQLQNGHEILAYLSGRMRKHYIRIVPGDSVKVALSPYDLSRGRIMFRER

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=72, Percent_Identity=62.5, Blast_Score=100, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1_TREPA (O83135)

Other databases:

- EMBL:   AE000520
- PIR:   E71366
- RefSeq:   NP_218537.1
- ProteinModelPortal:   O83135
- SMR:   O83135
- IntAct:   O83135
- GeneID:   2610769
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0097
- NMPDR:   fig|243276.1.peg.96
- TIGR:   TP_0097
- HOGENOM:   HBG286099
- OMA:   VQLDAGH
- ProtClustDB:   PRK00276
- BioCyc:   TPAL243276:TP_0097-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 8288; Mature: 8157

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEEAIEVDGVVKEALPNTTFRVQLQNGHEILAYLSGRMRKHYIRIVPGDSVKVALSPY
CCCCCEEEECCHHHHHCCCCEEEEEECCCCEEEEHHHCCCCEEEEEEECCCCEEEEECCC
DLSRGRIMFRER
CCCCCEEEEECC
>Mature Secondary Structure 
TKEEAIEVDGVVKEALPNTTFRVQLQNGHEILAYLSGRMRKHYIRIVPGDSVKVALSPY
CCCCEEEECCHHHHHCCCCEEEEEECCCCEEEEHHHCCCCEEEEEEECCCCEEEEECCC
DLSRGRIMFRER
CCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876