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The map label for this gene is crp [C]

Identifier: 189025323

GI number: 189025323

Start: 97422

End: 98657

Strand: Reverse

Name: crp [C]

Synonym: TPASS_0089

Alternate gene names: 189025323

Gene position: 98657-97422 (Counterclockwise)

Preceding gene: 189025324

Following gene: 189025322

Centisome position: 8.66

GC content: 45.39

Gene sequence:

>1236_bases
TTGTTACAGCTGACGTTTGTTAACTTCAAGAAGGGTTCTTACATACTAGTAGAGGGGAAAGCTGACGCAGATCTTTTCTA
TATCATTCACAGCGGTCAGGTATGTATTGCAAAACAAGTAGAGATAGTTGCAGAGGAGGAAGGAAACGTCCTAACCGCGG
GTAACTTTTTAGGTGTAGTTGCCTGCATGTCGCGGCATAATCAGATTGAAACTGCAGTTGCGCTCACTGATGTCGTGCTT
ATTGCAATTCGTTATGAGCAGTTCCCCCAGCTCATTGAAAAGAACGCGGCGATTGCTATGAAAATCATCCTTTCCTTCAC
AAAGAAAATGCGCTACCTCAATGAGGCGCTTACCCAATTGACATTGAAAAAACACACTGATGTGGATGTCTCGCATCTTT
TCGCTATTGGCGAATACTACGTCAAAATGACGAAGTTTGAACTTGCGCTCTATGCGTACTATCATTATCTCAAGGAAAGT
CCCAAGGGGACGTATGCAGAGGAAGCACGCAAACGATTTGTTGCGATTAAATCCACAGGAGTTAAGGTACCAGTAGAAAT
ACTCGAACCTAACATACTTGAAGCCACGCGCTGCTACGATCGAGAGGCGATGGTGTTCTGTGAGTGTCAATTGGGAAATG
AGTTTTACATCATTCAAAAAGGACATGTAAAAATTACTAAGATTGTTGATAACAATGAGGTAGTGCTGGCGATTTTAAAA
GAAGGAGATATGTTTGGGGAAATGGCGTTGCTGGAGAACAAGCCGCGTTCTGCAAGCGCCATTGTTATGTCTGATGGTTG
CCAGCTTTTGGCCGTGAACCGAAAGAACTTCCAACAGCTGGTAGCCACACAACCGCAATTGACTGCGCGTCTTACCACCA
CGCTCGCAGATCGCATCTGGTCGATGTACCGACAGCTCGCAAATACTTTGCTTCCGGAACCGACTGAAAAAATGTACGAT
ATGTTGGCCATCCAGTTAGAAAAGATTCGCTACATACCTAGCACCGGCAAGGCCTACGATTTTGAATTCGGTCCCATAGA
ACTCGCACACATGTGCGGTTTCCCTAAAGACATCGTCTCTCAGGTAACCGAAGACTTTTTACGAGAACCTATTGTCCGCT
GTGTCGATAACAAAATATCTGTCACCGACGACCTAGAATTGGTGAAGCGCGTTGCCTATTTTAAGAAAAAGCGTACCCTC
GCCAAGGCACGCAAGGACCCACACAACAGGCAGTAG

Upstream 100 bases:

>100_bases
AGTTCGCGAGACTCATGAGGCGGGCACCTGTGCACTGCAAGACGTACGGGTTGTCTTGTAAACAGAGCATAGAGCGACGA
TTAGGAAGGAGTGGGATACT

Downstream 100 bases:

>100_bases
ATGTATCCACACAAGGAGAGGAAAACGGCATGAATTATGCTAAAAATTGTATGGCGCTTGCGTTGGGCGGGGTGTTGCAT
ATGCAGTCTTATTTATGTTC

Product: cyclic nucleotide binding protein

Products: NA

Alternate protein names: Transcriptional Regulatory Protein; Catabolite Gene Activator; CAMP-Dependent Protein Kinase

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MLQLTFVNFKKGSYILVEGKADADLFYIIHSGQVCIAKQVEIVAEEEGNVLTAGNFLGVVACMSRHNQIETAVALTDVVL
IAIRYEQFPQLIEKNAAIAMKIILSFTKKMRYLNEALTQLTLKKHTDVDVSHLFAIGEYYVKMTKFELALYAYYHYLKES
PKGTYAEEARKRFVAIKSTGVKVPVEILEPNILEATRCYDREAMVFCECQLGNEFYIIQKGHVKITKIVDNNEVVLAILK
EGDMFGEMALLENKPRSASAIVMSDGCQLLAVNRKNFQQLVATQPQLTARLTTTLADRIWSMYRQLANTLLPEPTEKMYD
MLAIQLEKIRYIPSTGKAYDFEFGPIELAHMCGFPKDIVSQVTEDFLREPIVRCVDNKISVTDDLELVKRVAYFKKKRTL
AKARKDPHNRQ

Sequences:

>Translated_411_residues
MLQLTFVNFKKGSYILVEGKADADLFYIIHSGQVCIAKQVEIVAEEEGNVLTAGNFLGVVACMSRHNQIETAVALTDVVL
IAIRYEQFPQLIEKNAAIAMKIILSFTKKMRYLNEALTQLTLKKHTDVDVSHLFAIGEYYVKMTKFELALYAYYHYLKES
PKGTYAEEARKRFVAIKSTGVKVPVEILEPNILEATRCYDREAMVFCECQLGNEFYIIQKGHVKITKIVDNNEVVLAILK
EGDMFGEMALLENKPRSASAIVMSDGCQLLAVNRKNFQQLVATQPQLTARLTTTLADRIWSMYRQLANTLLPEPTEKMYD
MLAIQLEKIRYIPSTGKAYDFEFGPIELAHMCGFPKDIVSQVTEDFLREPIVRCVDNKISVTDDLELVKRVAYFKKKRTL
AKARKDPHNRQ
>Mature_411_residues
MLQLTFVNFKKGSYILVEGKADADLFYIIHSGQVCIAKQVEIVAEEEGNVLTAGNFLGVVACMSRHNQIETAVALTDVVL
IAIRYEQFPQLIEKNAAIAMKIILSFTKKMRYLNEALTQLTLKKHTDVDVSHLFAIGEYYVKMTKFELALYAYYHYLKES
PKGTYAEEARKRFVAIKSTGVKVPVEILEPNILEATRCYDREAMVFCECQLGNEFYIIQKGHVKITKIVDNNEVVLAILK
EGDMFGEMALLENKPRSASAIVMSDGCQLLAVNRKNFQQLVATQPQLTARLTTTLADRIWSMYRQLANTLLPEPTEKMYD
MLAIQLEKIRYIPSTGKAYDFEFGPIELAHMCGFPKDIVSQVTEDFLREPIVRCVDNKISVTDDLELVKRVAYFKKKRTL
AKARKDPHNRQ

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46822; Mature: 46822

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLTFVNFKKGSYILVEGKADADLFYIIHSGQVCIAKQVEIVAEEEGNVLTAGNFLGVV
CEEEEEEEECCCCEEEEECCCCCEEEEEEECCCEEEEEEEEEEEECCCCEEEECHHHHHH
ACMSRHNQIETAVALTDVVLIAIRYEQFPQLIEKNAAIAMKIILSFTKKMRYLNEALTQL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TLKKHTDVDVSHLFAIGEYYVKMTKFELALYAYYHYLKESPKGTYAEEARKRFVAIKSTG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEECCC
VKVPVEILEPNILEATRCYDREAMVFCECQLGNEFYIIQKGHVKITKIVDNNEVVLAILK
CEEEHHHCCCCHHHHHHHCCCCEEEEEEEECCCEEEEEEECCEEEEEEECCCCEEEEEEE
EGDMFGEMALLENKPRSASAIVMSDGCQLLAVNRKNFQQLVATQPQLTARLTTTLADRIW
CCCCHHHHHHHCCCCCCCEEEEEECCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHH
SMYRQLANTLLPEPTEKMYDMLAIQLEKIRYIPSTGKAYDFEFGPIELAHMCGFPKDIVS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCEEECCCCCCHHHHHCCCCHHHHH
QVTEDFLREPIVRCVDNKISVTDDLELVKRVAYFKKKRTLAKARKDPHNRQ
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLQLTFVNFKKGSYILVEGKADADLFYIIHSGQVCIAKQVEIVAEEEGNVLTAGNFLGVV
CEEEEEEEECCCCEEEEECCCCCEEEEEEECCCEEEEEEEEEEEECCCCEEEECHHHHHH
ACMSRHNQIETAVALTDVVLIAIRYEQFPQLIEKNAAIAMKIILSFTKKMRYLNEALTQL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TLKKHTDVDVSHLFAIGEYYVKMTKFELALYAYYHYLKESPKGTYAEEARKRFVAIKSTG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEECCC
VKVPVEILEPNILEATRCYDREAMVFCECQLGNEFYIIQKGHVKITKIVDNNEVVLAILK
CEEEHHHCCCCHHHHHHHCCCCEEEEEEEECCCEEEEEEECCEEEEEEECCCCEEEEEEE
EGDMFGEMALLENKPRSASAIVMSDGCQLLAVNRKNFQQLVATQPQLTARLTTTLADRIW
CCCCHHHHHHHCCCCCCCEEEEEECCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHH
SMYRQLANTLLPEPTEKMYDMLAIQLEKIRYIPSTGKAYDFEFGPIELAHMCGFPKDIVS
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCEEECCCCCCHHHHHCCCCHHHHH
QVTEDFLREPIVRCVDNKISVTDDLELVKRVAYFKKKRTLAKARKDPHNRQ
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA