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The map label for this gene is rlmH

Identifier: 188587484

GI number: 188587484

Start: 3126184

End: 3126663

Strand: Reverse

Name: rlmH

Synonym: Nther_2894

Alternate gene names: 188587484

Gene position: 3126663-3126184 (Counterclockwise)

Preceding gene: 188587485

Following gene: 188587483

Centisome position: 98.77

GC content: 31.46

Gene sequence:

>480_bases
ATGAAATTTAGAGTGGTAGCAGTAGGGAAGATTAAGGAAAAATATTTAATCCGAGGTATTGAAGAATATCAAAAACGATT
GCGACCGTATACGGGTCTAGAAATAACTGAAGTTAAAGATTCAGTTCTTCCCAATAAATTATATCAAGCAGAAATTGAAA
AGGTTTTAATAGAAGAAGAAAACCGAATTAAATCAAAATTGTCCTCAAGGGATTATATTATTGCTTTAGATTCGGAAGGT
TCCCAATTCACATCCGAAAATTTTGCTCAACAAATAGAAAACCTAACTCTAGAAGGAATTAACCAATTTACTTTTATCAT
TGGAGGCACCTTGGGTTTATCGAATTCATTAAAAAAGGAAGCTAATATGCTATTATCTTTTTCTAAGTTTACATTCCCTC
ATCAGTTAATGAGACTAATTTTGACTGAACAACTTTATCGAGCTATTAAGATAATCCACAATGAACCGTATCATTACTGA

Upstream 100 bases:

>100_bases
TATTTATTTTTATCAAACTCGCATGATGCGTTCAATTGAAAATTCTACAGTACCAATAAATAAATATAACAGCTTTTTTT
ATTAAAATGGGGGATTGAGG

Downstream 100 bases:

>100_bases
AAATTTAATATATACTCAAATAAGGAGGGAAACCCATGTCCGATCAATTAAATAATTATATTTTATTAATTACCGATGAA
TCTTTTGGTGAATCTGACAG

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKFRVVAVGKIKEKYLIRGIEEYQKRLRPYTGLEITEVKDSVLPNKLYQAEIEKVLIEEENRIKSKLSSRDYIIALDSEG
SQFTSENFAQQIENLTLEGINQFTFIIGGTLGLSNSLKKEANMLLSFSKFTFPHQLMRLILTEQLYRAIKIIHNEPYHY

Sequences:

>Translated_159_residues
MKFRVVAVGKIKEKYLIRGIEEYQKRLRPYTGLEITEVKDSVLPNKLYQAEIEKVLIEEENRIKSKLSSRDYIIALDSEG
SQFTSENFAQQIENLTLEGINQFTFIIGGTLGLSNSLKKEANMLLSFSKFTFPHQLMRLILTEQLYRAIKIIHNEPYHY
>Mature_159_residues
MKFRVVAVGKIKEKYLIRGIEEYQKRLRPYTGLEITEVKDSVLPNKLYQAEIEKVLIEEENRIKSKLSSRDYIIALDSEG
SQFTSENFAQQIENLTLEGINQFTFIIGGTLGLSNSLKKEANMLLSFSKFTFPHQLMRLILTEQLYRAIKIIHNEPYHY

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=158, Percent_Identity=31.0126582278481, Blast_Score=88, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_NATTJ (B2A3L2)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001919029.1
- ProteinModelPortal:   B2A3L2
- SMR:   B2A3L2
- GeneID:   6315109
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_2894
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 18535; Mature: 18535

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRVVAVGKIKEKYLIRGIEEYQKRLRPYTGLEITEVKDSVLPNKLYQAEIEKVLIEEE
CCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
NRIKSKLSSRDYIIALDSEGSQFTSENFAQQIENLTLEGINQFTFIIGGTLGLSNSLKKE
HHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCHHCCCHHHHEEECHHCCCHHHHHH
ANMLLSFSKFTFPHQLMRLILTEQLYRAIKIIHNEPYHY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKFRVVAVGKIKEKYLIRGIEEYQKRLRPYTGLEITEVKDSVLPNKLYQAEIEKVLIEEE
CCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
NRIKSKLSSRDYIIALDSEGSQFTSENFAQQIENLTLEGINQFTFIIGGTLGLSNSLKKE
HHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCHHCCCHHHHEEECHHCCCHHHHHH
ANMLLSFSKFTFPHQLMRLILTEQLYRAIKIIHNEPYHY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA