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The map label for this gene is kamA [H]

Identifier: 188587476

GI number: 188587476

Start: 3116836

End: 3118086

Strand: Direct

Name: kamA [H]

Synonym: Nther_2886

Alternate gene names: 188587476

Gene position: 3116836-3118086 (Clockwise)

Preceding gene: 188587474

Following gene: 188587477

Centisome position: 98.46

GC content: 39.97

Gene sequence:

>1251_bases
ATGACTGAATTTAATCCGTTATTTAGCCATGTAAGTACTCAGGATTGGCAAGATTGGAACTGGCAGTTAAAAAACAGGAT
CACTGATTTAGAATCACTAAAAGAGATTATTAACTTAACTGACAAAGAGGAAGAAGGAATCCAGCAAGCTTTAAAAACTT
TAAGAATGGCCATCACCCCTTATTATGCATCTTTAATGGATAAGGATGATCCTAGCTGCCCCATTAGACGCCAGGCAGTT
CCAAGCTCCCTGGAGTTGAATTTTGGTGATTCTGACCTGGAAGATCCTTTGAGTGAAGATACTGACTCTCCCGTAGAAGG
TATTACTCACCGATATCCAGATCGGGTATTGTTTCTGGTAACCGATCAATGCTCCATGTACTGTCGTCACTGCACCAGAA
GAAGAATAGCCGGTACCACAGATAAAGCTGCTCCTAAAGAAGTAGTTGATAATGCTATTGAATACATTAAAAACACCCCT
CGTGTGAGGGATGTACTAATTTCCGGTGGAGATGGTTTAATAATTTCAGATGAAAGGCTAGAATATATCCTGGACCAATT
ATATAAAATTGAGCACGTAGAGATAATTAGGATTGGCACTCGCGCTCCTGTAGTACTTCCTCAGAGAATCACGGATGATC
TGGTTTCAATATTGAAAAAATATCATCCTGTTTGGCTTAATACCCATTACAATCACCCTAAAGAATTAACCTCAGAAGCG
CAAAAAGCCCTGGCAAAATTAGCGGATGCTGGTATACCTTTAGGTAATCAGTCTGTGTTGTTAAAAGGAATCAACGATTG
TCCCGGAACTATGAAAAATTTAGTTCACGAGTTAGTTAAGCATAGAGTTCGACCTTATTACATTTATCAGTGTGATCTAT
CTCAAGGTATTGAACACTTTAGAACTTCCGTATCGGCAGGTCTTGAAATTGTGGAACATCTAAGAGGGCATACTAGTGGC
TTTGCCGTGCCAACCTATGTGGTAGATGCCCCAGGAGGCGGTGGAAAGATCCCTGTAATGCCCCAATATTTAATTTCTCA
ATCTCCTGAAAGTGTTATTCTAAGAAATTATGAAGGTGTAATAGCCAAGTACTCAGAACCACAAGATAAGAGCAGAGGGT
GTGGCAAACAAAGCTGCAACGATTGTCAGTTATCTGATAATACAGCCACAGGAGTGACAGCTCTAATGGAGGATAAAGAA
ATCAGCTTAGAACCTAGAAATTTAGCACGAAGACAACGTCGAAAAAAATAA

Upstream 100 bases:

>100_bases
GATAAGTCTGATATAATATCTATAAAATAATTTATTTGAGATCTAAAATGTTAAAAAATTCAATAAAAACACAAATAAAA
ATTAAAGGAGGCGGGTTTTG

Downstream 100 bases:

>100_bases
ATTTAAAATCATAATTTAACCGGTTGCAAATCCAGTGTTAGTATTAGATAATATAAGACATGAGTGCAAGTCGTGGAATA
CTATACAGGAGGGTGCCAGA

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MTEFNPLFSHVSTQDWQDWNWQLKNRITDLESLKEIINLTDKEEEGIQQALKTLRMAITPYYASLMDKDDPSCPIRRQAV
PSSLELNFGDSDLEDPLSEDTDSPVEGITHRYPDRVLFLVTDQCSMYCRHCTRRRIAGTTDKAAPKEVVDNAIEYIKNTP
RVRDVLISGGDGLIISDERLEYILDQLYKIEHVEIIRIGTRAPVVLPQRITDDLVSILKKYHPVWLNTHYNHPKELTSEA
QKALAKLADAGIPLGNQSVLLKGINDCPGTMKNLVHELVKHRVRPYYIYQCDLSQGIEHFRTSVSAGLEIVEHLRGHTSG
FAVPTYVVDAPGGGGKIPVMPQYLISQSPESVILRNYEGVIAKYSEPQDKSRGCGKQSCNDCQLSDNTATGVTALMEDKE
ISLEPRNLARRQRRKK

Sequences:

>Translated_416_residues
MTEFNPLFSHVSTQDWQDWNWQLKNRITDLESLKEIINLTDKEEEGIQQALKTLRMAITPYYASLMDKDDPSCPIRRQAV
PSSLELNFGDSDLEDPLSEDTDSPVEGITHRYPDRVLFLVTDQCSMYCRHCTRRRIAGTTDKAAPKEVVDNAIEYIKNTP
RVRDVLISGGDGLIISDERLEYILDQLYKIEHVEIIRIGTRAPVVLPQRITDDLVSILKKYHPVWLNTHYNHPKELTSEA
QKALAKLADAGIPLGNQSVLLKGINDCPGTMKNLVHELVKHRVRPYYIYQCDLSQGIEHFRTSVSAGLEIVEHLRGHTSG
FAVPTYVVDAPGGGGKIPVMPQYLISQSPESVILRNYEGVIAKYSEPQDKSRGCGKQSCNDCQLSDNTATGVTALMEDKE
ISLEPRNLARRQRRKK
>Mature_415_residues
TEFNPLFSHVSTQDWQDWNWQLKNRITDLESLKEIINLTDKEEEGIQQALKTLRMAITPYYASLMDKDDPSCPIRRQAVP
SSLELNFGDSDLEDPLSEDTDSPVEGITHRYPDRVLFLVTDQCSMYCRHCTRRRIAGTTDKAAPKEVVDNAIEYIKNTPR
VRDVLISGGDGLIISDERLEYILDQLYKIEHVEIIRIGTRAPVVLPQRITDDLVSILKKYHPVWLNTHYNHPKELTSEAQ
KALAKLADAGIPLGNQSVLLKGINDCPGTMKNLVHELVKHRVRPYYIYQCDLSQGIEHFRTSVSAGLEIVEHLRGHTSGF
AVPTYVVDAPGGGGKIPVMPQYLISQSPESVILRNYEGVIAKYSEPQDKSRGCGKQSCNDCQLSDNTATGVTALMEDKEI
SLEPRNLARRQRRKK

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=332, Percent_Identity=33.433734939759, Blast_Score=182, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 47026; Mature: 46895

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFNPLFSHVSTQDWQDWNWQLKNRITDLESLKEIINLTDKEEEGIQQALKTLRMAITP
CCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
YYASLMDKDDPSCPIRRQAVPSSLELNFGDSDLEDPLSEDTDSPVEGITHRYPDRVLFLV
HHHHHHCCCCCCCCCHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEE
TDQCSMYCRHCTRRRIAGTTDKAAPKEVVDNAIEYIKNTPRVRDVLISGGDGLIISDERL
ECHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHEEEEECCCEEEECHHHH
EYILDQLYKIEHVEIIRIGTRAPVVLPQRITDDLVSILKKYHPVWLNTHYNHPKELTSEA
HHHHHHHHHCCCEEEEEECCCCCEECHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHH
QKALAKLADAGIPLGNQSVLLKGINDCPGTMKNLVHELVKHRVRPYYIYQCDLSQGIEHF
HHHHHHHHHCCCCCCCCHHEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
RTSVSAGLEIVEHLRGHTSGFAVPTYVVDAPGGGGKIPVMPQYLISQSPESVILRNYEGV
HHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCHHHHCCCCCC
IAKYSEPQDKSRGCGKQSCNDCQLSDNTATGVTALMEDKEISLEPRNLARRQRRKK
EECCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
TEFNPLFSHVSTQDWQDWNWQLKNRITDLESLKEIINLTDKEEEGIQQALKTLRMAITP
CCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
YYASLMDKDDPSCPIRRQAVPSSLELNFGDSDLEDPLSEDTDSPVEGITHRYPDRVLFLV
HHHHHHCCCCCCCCCHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEE
TDQCSMYCRHCTRRRIAGTTDKAAPKEVVDNAIEYIKNTPRVRDVLISGGDGLIISDERL
ECHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHEEEEECCCEEEECHHHH
EYILDQLYKIEHVEIIRIGTRAPVVLPQRITDDLVSILKKYHPVWLNTHYNHPKELTSEA
HHHHHHHHHCCCEEEEEECCCCCEECHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHH
QKALAKLADAGIPLGNQSVLLKGINDCPGTMKNLVHELVKHRVRPYYIYQCDLSQGIEHF
HHHHHHHHHCCCCCCCCHHEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHH
RTSVSAGLEIVEHLRGHTSGFAVPTYVVDAPGGGGKIPVMPQYLISQSPESVILRNYEGV
HHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCHHHHHCCCCCHHHHCCCCCC
IAKYSEPQDKSRGCGKQSCNDCQLSDNTATGVTALMEDKEISLEPRNLARRQRRKK
EECCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]