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The map label for this gene is mnaA [H]

Identifier: 188587445

GI number: 188587445

Start: 3086788

End: 3087969

Strand: Reverse

Name: mnaA [H]

Synonym: Nther_2855

Alternate gene names: 188587445

Gene position: 3087969-3086788 (Counterclockwise)

Preceding gene: 188587446

Following gene: 188587442

Centisome position: 97.55

GC content: 38.75

Gene sequence:

>1182_bases
ATGAAACACCGGGTTGTTAGCGTCTTTGGAACAAGGCCAGAAGCTATCAAAATGGCCCCCCTGGTTTCCGCCATTGAATC
TTCTCCTAATCTGACATCTTCAGTGGTGGTAACAGCCCAGCACAGAGAAATGCTGGACCAGGTGCTAGATCTTTTTAAAA
TTGAGCCCGATTACGATTTGGACATAATGAAAACTAGACAAAGCCTCTCAGAAATCACTTCTAATGTAATTTTAAAATTA
GAACAAATTCTCCAAGATATGAACCCTCATCTGCTACTAGTACACGGAGATACTACTACTACTTTTGCCTCGGCCTTATC
TGCATATTACCAAAAGATTTCTATAGGACATGTGGAAGCGGGATTGAGAACATGGGACAAATATGCTCCATTTCCAGAAG
AAATGAACAGAAATTTGGTAGGTCCCTTGGCTGATCTTCATTTTGCACCCACAAGTAAGGCGAAGAACAATTTATTAACT
GAAGGGATTTCCGAAAATAAGATTTTTGTGACTGGAAATACTGTCGTAGATGCTTTGAAGACATCAGTTCAACCCCAATA
CCAATTTCAAGATCCTAAACTTGCCAGCTTAGATTTACCTTCTCTCTCTAATCGCACAACAGCTAATAAAAAACTTATAA
CTTTAGAAGTTCATCGCCGAGAAAACTGGGGTGCACCTATGAAAAATATATTTAAAGGAATTAAGAAATTAGTAGATGAA
TTTCAAGATGTTATGGTAGTATTTCCCGTTCATCGAAATCCTGCGGTGAGAGAAACAGCATACGAAATTCTTGGAAATCA
TGATCGGATAATATTAACTGATCCTTTACCAACAAGAGACTTCCATAATCTAATCGCTAGAAGTTATCTGGTGTTAACTG
ATTCAGGTGGAATTCAAGAAGAAGCACCTTCCTTTGGAGTTCCTGTCTTAGTAGTGAGAGAAAAAACAGAACGAGAAGAG
GGATTGAAACAGGGGACTGTTATGCTCATAGGACGTGAACAAGAGCGAATATATCAAGAATCCAAGAAATTGCTAACAGA
TAAAGAACTTTATGAAACCATGCGCAAACAAGACAATCCTTATGGAGACGGTTTTGCCTCTTCAAGAATTGTTTCTGCTA
TTGAACATTATTATGGCCATAAAGATGCCCCAGAACCAGATTACAAAGTCAGCCCGGTATAA

Upstream 100 bases:

>100_bases
AATGCCGGCGTGAGTGAAATAGTAGCTGAACGGAGCTATCCAGATGAACTTTCAAAAGAAGTACTTGCCGAAGCAGGTAT
TAAAGTCAGGAGGTATGGTA

Downstream 100 bases:

>100_bases
TTGTTATCCGGGCTGACTTTTTTAATCTAGTTTTTCTTTAATTTTTTGTCCTGTAGGTGTAATAGCCAGGCCACCTTCAG
CTGTTTCTCGTAAAGTTGGA

Product: UDP-N-Acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKHRVVSVFGTRPEAIKMAPLVSAIESSPNLTSSVVVTAQHREMLDQVLDLFKIEPDYDLDIMKTRQSLSEITSNVILKL
EQILQDMNPHLLLVHGDTTTTFASALSAYYQKISIGHVEAGLRTWDKYAPFPEEMNRNLVGPLADLHFAPTSKAKNNLLT
EGISENKIFVTGNTVVDALKTSVQPQYQFQDPKLASLDLPSLSNRTTANKKLITLEVHRRENWGAPMKNIFKGIKKLVDE
FQDVMVVFPVHRNPAVRETAYEILGNHDRIILTDPLPTRDFHNLIARSYLVLTDSGGIQEEAPSFGVPVLVVREKTEREE
GLKQGTVMLIGREQERIYQESKKLLTDKELYETMRKQDNPYGDGFASSRIVSAIEHYYGHKDAPEPDYKVSPV

Sequences:

>Translated_393_residues
MKHRVVSVFGTRPEAIKMAPLVSAIESSPNLTSSVVVTAQHREMLDQVLDLFKIEPDYDLDIMKTRQSLSEITSNVILKL
EQILQDMNPHLLLVHGDTTTTFASALSAYYQKISIGHVEAGLRTWDKYAPFPEEMNRNLVGPLADLHFAPTSKAKNNLLT
EGISENKIFVTGNTVVDALKTSVQPQYQFQDPKLASLDLPSLSNRTTANKKLITLEVHRRENWGAPMKNIFKGIKKLVDE
FQDVMVVFPVHRNPAVRETAYEILGNHDRIILTDPLPTRDFHNLIARSYLVLTDSGGIQEEAPSFGVPVLVVREKTEREE
GLKQGTVMLIGREQERIYQESKKLLTDKELYETMRKQDNPYGDGFASSRIVSAIEHYYGHKDAPEPDYKVSPV
>Mature_393_residues
MKHRVVSVFGTRPEAIKMAPLVSAIESSPNLTSSVVVTAQHREMLDQVLDLFKIEPDYDLDIMKTRQSLSEITSNVILKL
EQILQDMNPHLLLVHGDTTTTFASALSAYYQKISIGHVEAGLRTWDKYAPFPEEMNRNLVGPLADLHFAPTSKAKNNLLT
EGISENKIFVTGNTVVDALKTSVQPQYQFQDPKLASLDLPSLSNRTTANKKLITLEVHRRENWGAPMKNIFKGIKKLVDE
FQDVMVVFPVHRNPAVRETAYEILGNHDRIILTDPLPTRDFHNLIARSYLVLTDSGGIQEEAPSFGVPVLVVREKTEREE
GLKQGTVMLIGREQERIYQESKKLLTDKELYETMRKQDNPYGDGFASSRIVSAIEHYYGHKDAPEPDYKVSPV

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=373, Percent_Identity=50.6702412868633, Blast_Score=351, Evalue=5e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 44367; Mature: 44367

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHRVVSVFGTRPEAIKMAPLVSAIESSPNLTSSVVVTAQHREMLDQVLDLFKIEPDYDL
CCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCH
DIMKTRQSLSEITSNVILKLEQILQDMNPHLLLVHGDTTTTFASALSAYYQKISIGHVEA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
GLRTWDKYAPFPEEMNRNLVGPLADLHFAPTSKAKNNLLTEGISENKIFVTGNTVVDALK
HHHHHHHCCCCHHHHCCCCCCCHHHCCCCCCCHHHHHHHHCCCCCCEEEEECHHHHHHHH
TSVQPQYQFQDPKLASLDLPSLSNRTTANKKLITLEVHRRENWGAPMKNIFKGIKKLVDE
HCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
FQDVMVVFPVHRNPAVRETAYEILGNHDRIILTDPLPTRDFHNLIARSYLVLTDSGGIQE
HHCEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHEEEEEECCCCCCC
EAPSFGVPVLVVREKTEREEGLKQGTVMLIGREQERIYQESKKLLTDKELYETMRKQDNP
CCCCCCCCEEEEECHHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHHHCCCC
YGDGFASSRIVSAIEHYYGHKDAPEPDYKVSPV
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKHRVVSVFGTRPEAIKMAPLVSAIESSPNLTSSVVVTAQHREMLDQVLDLFKIEPDYDL
CCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCH
DIMKTRQSLSEITSNVILKLEQILQDMNPHLLLVHGDTTTTFASALSAYYQKISIGHVEA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
GLRTWDKYAPFPEEMNRNLVGPLADLHFAPTSKAKNNLLTEGISENKIFVTGNTVVDALK
HHHHHHHCCCCHHHHCCCCCCCHHHCCCCCCCHHHHHHHHCCCCCCEEEEECHHHHHHHH
TSVQPQYQFQDPKLASLDLPSLSNRTTANKKLITLEVHRRENWGAPMKNIFKGIKKLVDE
HCCCCCEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
FQDVMVVFPVHRNPAVRETAYEILGNHDRIILTDPLPTRDFHNLIARSYLVLTDSGGIQE
HHCEEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHEEEEEECCCCCCC
EAPSFGVPVLVVREKTEREEGLKQGTVMLIGREQERIYQESKKLLTDKELYETMRKQDNP
CCCCCCCCEEEEECHHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCHHHHHHHHHHCCCC
YGDGFASSRIVSAIEHYYGHKDAPEPDYKVSPV
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]