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The map label for this gene is sdaAA [H]

Identifier: 188587444

GI number: 188587444

Start: 3085852

End: 3086766

Strand: Direct

Name: sdaAA [H]

Synonym: Nther_2854

Alternate gene names: 188587444

Gene position: 3085852-3086766 (Clockwise)

Preceding gene: 188587443

Following gene: 188587453

Centisome position: 97.48

GC content: 41.2

Gene sequence:

>915_bases
ATGAGCCATAACAATATCAGAGAAAGTTACAAAAACGGAAAGGACTTCGAATTTAATTCTTTAAGAACCTTGAAAGACTT
GGCCAATCAGCATAATAAAAATATATCTTGGATAGTTAAACATTATGAAGCCCAAACTGCACAACAGGATGTTAAAAAAC
TTGAGAAATTAATGGATGACCGTATTAGGATTATGGAAGATTCTGTAACAAAGGGGATTGAAGATCCGAAGCGCTCCTTA
GGAGGATTAATAGGTGGAGAAGGTAATAAAATGACTCAATATATAGAGCAGAACACTCCTCTAATGGGTAGCTTAGGCGG
CCTCGCTTTATCTAGGGCCCTAGCAGTTTCAGAGGTTAATGCATCTATGGGAAAAATTGTGGCCTCTCCTACTGCAGGTG
CCTGCGGAATTTTACCAGGAGTTTTATTGACAGTATCTGAACACAAAAATCTTAGCCGGAAACAATTAATTGACGGCTTC
TTTACGGCCTCTGGCATTGGAATGGTTGTTGCTGAGAAAGCAACAGTAGCTGGAGCCGAAGGAGGATGTCAAGCCGAATG
TGGTGTTGGTGGTGCCATGGCAGCTGGTGCAGCAGTTGAACTAATGGGAGGTAGCCCAGAAATGGTTTTAAATGCTGTAG
CTATTAGCTTAAAAGGTGTTTTAGGTCTAGTTTGCGACCCTGTGGGGGGATTAGTGGAGGTGCCCTGCCAAAAGAGAAAT
ACCATGGCTGTATCTCAAGCTTTAGCTTCTGCTGATATGGCTTTAGCTGATATAAAGAGCGTAATACCAGCTGATGAAGT
AATTGAAGCTATGTATGATATTGGTAAAAGTCTGCCTCCAACTTTACGAGAAACAGCTGAAGGTGGCCTGGCTATTACAC
CTACAGGACAAAAAATTAAAGAAAAACTAGATTAA

Upstream 100 bases:

>100_bases
CTATTAAAGATAACTTAACCCAGGACGATGATATAGAACAAGCAAGAATTATTCAGCCGCTATAGATTTAACTAGAACTC
AATGATTAGGAGGGATAAAT

Downstream 100 bases:

>100_bases
AAAAGTCAGCCCGGATAACAATTATACCGGGCTGACTTTGTAATCTGGTTCTGGGGCATCTTTATGGCCATAATAATGTT
CAATAGCAGAAACAATTCTT

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSHNNIRESYKNGKDFEFNSLRTLKDLANQHNKNISWIVKHYEAQTAQQDVKKLEKLMDDRIRIMEDSVTKGIEDPKRSL
GGLIGGEGNKMTQYIEQNTPLMGSLGGLALSRALAVSEVNASMGKIVASPTAGACGILPGVLLTVSEHKNLSRKQLIDGF
FTASGIGMVVAEKATVAGAEGGCQAECGVGGAMAAGAAVELMGGSPEMVLNAVAISLKGVLGLVCDPVGGLVEVPCQKRN
TMAVSQALASADMALADIKSVIPADEVIEAMYDIGKSLPPTLRETAEGGLAITPTGQKIKEKLD

Sequences:

>Translated_304_residues
MSHNNIRESYKNGKDFEFNSLRTLKDLANQHNKNISWIVKHYEAQTAQQDVKKLEKLMDDRIRIMEDSVTKGIEDPKRSL
GGLIGGEGNKMTQYIEQNTPLMGSLGGLALSRALAVSEVNASMGKIVASPTAGACGILPGVLLTVSEHKNLSRKQLIDGF
FTASGIGMVVAEKATVAGAEGGCQAECGVGGAMAAGAAVELMGGSPEMVLNAVAISLKGVLGLVCDPVGGLVEVPCQKRN
TMAVSQALASADMALADIKSVIPADEVIEAMYDIGKSLPPTLRETAEGGLAITPTGQKIKEKLD
>Mature_303_residues
SHNNIRESYKNGKDFEFNSLRTLKDLANQHNKNISWIVKHYEAQTAQQDVKKLEKLMDDRIRIMEDSVTKGIEDPKRSLG
GLIGGEGNKMTQYIEQNTPLMGSLGGLALSRALAVSEVNASMGKIVASPTAGACGILPGVLLTVSEHKNLSRKQLIDGFF
TASGIGMVVAEKATVAGAEGGCQAECGVGGAMAAGAAVELMGGSPEMVLNAVAISLKGVLGLVCDPVGGLVEVPCQKRNT
MAVSQALASADMALADIKSVIPADEVIEAMYDIGKSLPPTLRETAEGGLAITPTGQKIKEKLD

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=182, Percent_Identity=45.0549450549451, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788116, Length=182, Percent_Identity=45.6043956043956, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1789161, Length=182, Percent_Identity=43.956043956044, Blast_Score=141, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 31879; Mature: 31748

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNNIRESYKNGKDFEFNSLRTLKDLANQHNKNISWIVKHYEAQTAQQDVKKLEKLMDD
CCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RIRIMEDSVTKGIEDPKRSLGGLIGGEGNKMTQYIEQNTPLMGSLGGLALSRALAVSEVN
HHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ASMGKIVASPTAGACGILPGVLLTVSEHKNLSRKQLIDGFFTASGIGMVVAEKATVAGAE
HHHHHEEECCCCCHHHHHHHHHEEEHHHCCCHHHHHHHHHHHHCCCCEEEECCHHCCCCC
GGCQAECGVGGAMAAGAAVELMGGSPEMVLNAVAISLKGVLGLVCDPVGGLVEVPCQKRN
CCCCCCCCCCHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCH
TMAVSQALASADMALADIKSVIPADEVIEAMYDIGKSLPPTLRETAEGGLAITPTGQKIK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHCCCCEEECCCCHHHH
EKLD
HHCC
>Mature Secondary Structure 
SHNNIRESYKNGKDFEFNSLRTLKDLANQHNKNISWIVKHYEAQTAQQDVKKLEKLMDD
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RIRIMEDSVTKGIEDPKRSLGGLIGGEGNKMTQYIEQNTPLMGSLGGLALSRALAVSEVN
HHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ASMGKIVASPTAGACGILPGVLLTVSEHKNLSRKQLIDGFFTASGIGMVVAEKATVAGAE
HHHHHEEECCCCCHHHHHHHHHEEEHHHCCCHHHHHHHHHHHHCCCCEEEECCHHCCCCC
GGCQAECGVGGAMAAGAAVELMGGSPEMVLNAVAISLKGVLGLVCDPVGGLVEVPCQKRN
CCCCCCCCCCHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCH
TMAVSQALASADMALADIKSVIPADEVIEAMYDIGKSLPPTLRETAEGGLAITPTGQKIK
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHCCCCEEECCCCHHHH
EKLD
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]