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The map label for this gene is mtnX [H]

Identifier: 188587367

GI number: 188587367

Start: 2996132

End: 2996821

Strand: Reverse

Name: mtnX [H]

Synonym: Nther_2774

Alternate gene names: 188587367

Gene position: 2996821-2996132 (Counterclockwise)

Preceding gene: 188587368

Following gene: 188587366

Centisome position: 94.67

GC content: 32.9

Gene sequence:

>690_bases
ATGTCAAAAGATATGGATTTAAATCAACTAGCCGTTATAACAGATTTCGATGGCACAATTACTTCTCAAGATACAAATGA
TCTGATTATTGATAACTTTGGTACTGAAACAAACCAGGAAGTTGAGCGACTTTTTCAAAATAGCAAGATTGGCACCCGGG
AGGCCATGAAAAGACATTTTAAAGAAATTAAAATTTTGGAAAATCAATACAGTGAATTTCTATTACAGAACACAGAAGTT
CGAACTGGCTTTAAAAGTTTTACCCAAATATGTATGAAGCATAAAATTCCCCTATATGTGGTCAGTGGCGGTTTTACAAA
TATTATCGAGAAAATATTACACAGTGTTGATCCATTGATTAACTCCTATGCCAGAATTTATGCCAATCAATTACACTTCA
ATAAAAATAATATCAGCATTACTTTTTATCATGATTCTGTCAACTGCATTAAAGATTTTGGCCCCTGCGGGAATTGTAAA
CGCAGTCATGTAAAGAATTTACAAGCACAGCATAAGCAGGTTATATTTATAGGAGATGGACTGACAGATAGATGTGGTGC
AGAAACTTCTGATTTAGTTTTTGCTCGTAGCAACCTAGCTGAATTTTGTAGAGAGCATGGGATATCTTTTTATAATTTTA
AAGACTTTAATGATGTACAGAGACAAATCTTTAACATATTTCTTAACTGA

Upstream 100 bases:

>100_bases
TTATAATAATCGTAGTCGTTGGTATAAACACAGATAAACAGATATTTTGTCTATATTTCCCGGGAAATGTCGGGAGTAGC
TTTACTGGGGTGATAAAAAA

Downstream 100 bases:

>100_bases
TCTGAAATAGCAGTCTAAGAACTAACCTAGAGATAGAAAAGGCTTGTTAAAGCTGGAAGGGAAGTGGTACTTTACCTTCC
AGCTTTTTTTCTTTTAGTTG

Product: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Products: L-serine; D-serine; phosphate

Alternate protein names: HK-MTPenyl-1-P phosphatase [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSKDMDLNQLAVITDFDGTITSQDTNDLIIDNFGTETNQEVERLFQNSKIGTREAMKRHFKEIKILENQYSEFLLQNTEV
RTGFKSFTQICMKHKIPLYVVSGGFTNIIEKILHSVDPLINSYARIYANQLHFNKNNISITFYHDSVNCIKDFGPCGNCK
RSHVKNLQAQHKQVIFIGDGLTDRCGAETSDLVFARSNLAEFCREHGISFYNFKDFNDVQRQIFNIFLN

Sequences:

>Translated_229_residues
MSKDMDLNQLAVITDFDGTITSQDTNDLIIDNFGTETNQEVERLFQNSKIGTREAMKRHFKEIKILENQYSEFLLQNTEV
RTGFKSFTQICMKHKIPLYVVSGGFTNIIEKILHSVDPLINSYARIYANQLHFNKNNISITFYHDSVNCIKDFGPCGNCK
RSHVKNLQAQHKQVIFIGDGLTDRCGAETSDLVFARSNLAEFCREHGISFYNFKDFNDVQRQIFNIFLN
>Mature_228_residues
SKDMDLNQLAVITDFDGTITSQDTNDLIIDNFGTETNQEVERLFQNSKIGTREAMKRHFKEIKILENQYSEFLLQNTEVR
TGFKSFTQICMKHKIPLYVVSGGFTNIIEKILHSVDPLINSYARIYANQLHFNKNNISITFYHDSVNCIKDFGPCGNCKR
SHVKNLQAQHKQVIFIGDGLTDRCGAETSDLVFARSNLAEFCREHGISFYNFKDFNDVQRQIFNIFLN

Specific function: Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) [H]

COG id: COG4359

COG function: function code E; Uncharacterized conserved protein, possibly involved in methylthioadenosine recycling

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MtnX family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324318, Length=234, Percent_Identity=26.4957264957265, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR017718
- InterPro:   IPR006383
- InterPro:   IPR006384 [H]

Pfam domain/function: NA

EC number: 3.1.3.3

Molecular weight: Translated: 26426; Mature: 26295

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDMDLNQLAVITDFDGTITSQDTNDLIIDNFGTETNQEVERLFQNSKIGTREAMKRHF
CCCCCCCCCEEEEEECCCEECCCCCCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHH
KEIKILENQYSEFLLQNTEVRTGFKSFTQICMKHKIPLYVVSGGFTNIIEKILHSVDPLI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
NSYARIYANQLHFNKNNISITFYHDSVNCIKDFGPCGNCKRSHVKNLQAQHKQVIFIGDG
HHHHHHHHHHHEECCCCEEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECC
LTDRCGAETSDLVFARSNLAEFCREHGISFYNFKDFNDVQRQIFNIFLN
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKDMDLNQLAVITDFDGTITSQDTNDLIIDNFGTETNQEVERLFQNSKIGTREAMKRHF
CCCCCCCCEEEEEECCCEECCCCCCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHH
KEIKILENQYSEFLLQNTEVRTGFKSFTQICMKHKIPLYVVSGGFTNIIEKILHSVDPLI
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
NSYARIYANQLHFNKNNISITFYHDSVNCIKDFGPCGNCKRSHVKNLQAQHKQVIFIGDG
HHHHHHHHHHHEECCCCEEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEEECC
LTDRCGAETSDLVFARSNLAEFCREHGISFYNFKDFNDVQRQIFNIFLN
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-O-phosphoserine; D-O-phosphoserine; H2O

Specific reaction: L(or D)-O-phosphoserine + H2O = L(or D)-serine + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921; 14551435 [H]