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The map label for this gene is pyrR

Identifier: 188587359

GI number: 188587359

Start: 2986827

End: 2987375

Strand: Reverse

Name: pyrR

Synonym: Nther_2766

Alternate gene names: 188587359

Gene position: 2987375-2986827 (Counterclockwise)

Preceding gene: 188587361

Following gene: 188587358

Centisome position: 94.37

GC content: 38.25

Gene sequence:

>549_bases
GTGGTTCAAGAAAAAGCGGAGATCATGGATCAAGAAAAATTTAATCGTACTTTGACTCGCATTTCCCACGAAATTATTGA
GAAAAATAAAGGTATAGATGATCTTGTTCTGATCGGCATTAGAACTCGAGGAGTACCACTGGCAGAACGACTGGCTCATA
AAATTGAGGAAATAGAAGGGGAAAGTATAGCTACTGGCTTACTTGATATTACACTCTACCGGGATGATTTAAGCACTTTA
TCTGAAAAACCTATTTTAAATAAAACTGAGGTTCCCTTTTCCATTAAAAATAAGAAAGTTGTATTAGTCGACGATGTCCT
TTACACTGGTAGGACGGCCAGAGCAGCTCTGGATGCTGTAATTGATTTGGGTAGACCTAAGTATATCCAACTGGCAGTAA
TTGTAGACAGGGGACACCGAGAACTGCCAATTAGAGCTGACTATGTTGGGAAGAATGTTCCTACATCTAAAAAAGAATTA
ATTTCAGTTAGATTATCTGAAATTGACGGAGAAGACAGAGTCATGATCGAAGAGACGGTAAAGGAATAA

Upstream 100 bases:

>100_bases
GTATACTTTGGATAAGTTTGCTAATATTCCTGTCTCACTGAGATAGGAATTTTTTATAAACAAATATTTTAATGGGGCTG
AGTTCCAGGGAGGTGTTAAA

Downstream 100 bases:

>100_bases
AGGATTTTTAATTTACAAGATTAAGTTCCCTTGAAATTAGTCCCGTGAGGCTAATAAGGGAGGTGATGCTAGGCGTATTG
TGTCAAATTATGTCCAATTA

Product: Uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MVQEKAEIMDQEKFNRTLTRISHEIIEKNKGIDDLVLIGIRTRGVPLAERLAHKIEEIEGESIATGLLDITLYRDDLSTL
SEKPILNKTEVPFSIKNKKVVLVDDVLYTGRTARAALDAVIDLGRPKYIQLAVIVDRGHRELPIRADYVGKNVPTSKKEL
ISVRLSEIDGEDRVMIEETVKE

Sequences:

>Translated_182_residues
MVQEKAEIMDQEKFNRTLTRISHEIIEKNKGIDDLVLIGIRTRGVPLAERLAHKIEEIEGESIATGLLDITLYRDDLSTL
SEKPILNKTEVPFSIKNKKVVLVDDVLYTGRTARAALDAVIDLGRPKYIQLAVIVDRGHRELPIRADYVGKNVPTSKKEL
ISVRLSEIDGEDRVMIEETVKE
>Mature_182_residues
MVQEKAEIMDQEKFNRTLTRISHEIIEKNKGIDDLVLIGIRTRGVPLAERLAHKIEEIEGESIATGLLDITLYRDDLSTL
SEKPILNKTEVPFSIKNKKVVLVDDVLYTGRTARAALDAVIDLGRPKYIQLAVIVDRGHRELPIRADYVGKNVPTSKKEL
ISVRLSEIDGEDRVMIEETVKE

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_NATTJ (B2A2U8)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001918904.1
- ProteinModelPortal:   B2A2U8
- SMR:   B2A2U8
- GeneID:   6315751
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_2766
- HOGENOM:   HBG641958
- OMA:   ILDITLY
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 20571; Mature: 20571

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQEKAEIMDQEKFNRTLTRISHEIIEKNKGIDDLVLIGIRTRGVPLAERLAHKIEEIEG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCC
ESIATGLLDITLYRDDLSTLSEKPILNKTEVPFSIKNKKVVLVDDVLYTGRTARAALDAV
CHHHHHHEEEEEECCHHHHHHCCCCCCCCCCCEEECCCEEEEEECHHHCCCHHHHHHHHH
IDLGRPKYIQLAVIVDRGHRELPIRADYVGKNVPTSKKELISVRLSEIDGEDRVMIEETV
HHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEHHHHH
KE
CC
>Mature Secondary Structure
MVQEKAEIMDQEKFNRTLTRISHEIIEKNKGIDDLVLIGIRTRGVPLAERLAHKIEEIEG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCC
ESIATGLLDITLYRDDLSTLSEKPILNKTEVPFSIKNKKVVLVDDVLYTGRTARAALDAV
CHHHHHHEEEEEECCHHHHHHCCCCCCCCCCCEEECCCEEEEEECHHHCCCHHHHHHHHH
IDLGRPKYIQLAVIVDRGHRELPIRADYVGKNVPTSKKELISVRLSEIDGEDRVMIEETV
HHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCEEHHHHH
KE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA