| Definition | Natranaerobius thermophilus JW/NM-WN-LF, complete genome. |
|---|---|
| Accession | NC_010718 |
| Length | 3,165,557 |
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The map label for this gene is livG [H]
Identifier: 188587331
GI number: 188587331
Start: 2955234
End: 2956040
Strand: Reverse
Name: livG [H]
Synonym: Nther_2737
Alternate gene names: 188587331
Gene position: 2956040-2955234 (Counterclockwise)
Preceding gene: 188587332
Following gene: 188587329
Centisome position: 93.38
GC content: 38.54
Gene sequence:
>807_bases ATGAAGGACCAGGGGGTTGATATTACTATGGCTTTATTATCAATTGAAAATTTAACTAAAAGCTTTGGCGGTTTAGTTGC GGTGAATGAGTTATCTATGGATGTAAACCAACAAGAGATTCACGGCTTAATTGGACCCAATGGGGCGGGGAAAACTACCG TTTTTAATTGTATCAGTAAATTCTATACACCGGATAAGGGAAAAATCCTTTTAGATAATGGGCAAAATGTTTTAAATTTA TCACCACATCAGGTAATAAGATGCGGTATTAGTAGGACATTTCAAAATGTGGAACTTTTTGATAATTTAACTGTCCTAGA GAACTTAATGGTAGGTTATCATTCCAATATGAGAAGTGGTTTACTTTTGGAAGGTTTAAGCCTACCTGGTAGTTTAAGTG ATGAATCTAAAGCCAGGGAACGAGCTGAATCCATAGCGGAATTTTTAAATATAAAGGATACTTTGAAAATGCCAGCAACC TCTCAACCCCTTGGAATTCAGAAAAAGATTGAGATGGGTCGGGCTTTAATCTCCCAGCCTAAATTGCTGTTACTTGATGA ACCGGCAGGAGGAATGAATGAAAGAGAGACTCAAAACTTGGCTGGGTTAATTACACAAGTTCAGGAAGAGTTCGGCATAT CCGTTATCCTAGTAGAACATGATATGAGCCTGGTAATGGAAATTTGCCATAAAATTACCGTGATGAACTTTGGCAGAAAA ATTGCCTGTGGCAATCCCGCAGACATCCAAAAGAACCCTAAGGTACAAGAGGCTTATCTGGGTAAAGGAGAGGATGCAAG TGCTTAA
Upstream 100 bases:
>100_bases CTGGCAATTATCGGTGTGAGCTATCAATCAGGTACAGAAAGCGCTAAATCTGACAATTCTTTTAATAGCTCAAAAGAAAA CCAAACTTCGGAATCTAAAC
Downstream 100 bases:
>100_bases ATTAGTTGATATAACAGCTTATTACGGATATATCAAAGCTTTAGAGGACATTAACATGTCTATAGAGGAGGGGGAGATCA CAGCACTTTTGGGTGCAAAC
Product: ABC transporter related
Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein G [H]
Number of amino acids: Translated: 268; Mature: 268
Protein sequence:
>268_residues MKDQGVDITMALLSIENLTKSFGGLVAVNELSMDVNQQEIHGLIGPNGAGKTTVFNCISKFYTPDKGKILLDNGQNVLNL SPHQVIRCGISRTFQNVELFDNLTVLENLMVGYHSNMRSGLLLEGLSLPGSLSDESKARERAESIAEFLNIKDTLKMPAT SQPLGIQKKIEMGRALISQPKLLLLDEPAGGMNERETQNLAGLITQVQEEFGISVILVEHDMSLVMEICHKITVMNFGRK IACGNPADIQKNPKVQEAYLGKGEDASA
Sequences:
>Translated_268_residues MKDQGVDITMALLSIENLTKSFGGLVAVNELSMDVNQQEIHGLIGPNGAGKTTVFNCISKFYTPDKGKILLDNGQNVLNL SPHQVIRCGISRTFQNVELFDNLTVLENLMVGYHSNMRSGLLLEGLSLPGSLSDESKARERAESIAEFLNIKDTLKMPAT SQPLGIQKKIEMGRALISQPKLLLLDEPAGGMNERETQNLAGLITQVQEEFGISVILVEHDMSLVMEICHKITVMNFGRK IACGNPADIQKNPKVQEAYLGKGEDASA >Mature_268_residues MKDQGVDITMALLSIENLTKSFGGLVAVNELSMDVNQQEIHGLIGPNGAGKTTVFNCISKFYTPDKGKILLDNGQNVLNL SPHQVIRCGISRTFQNVELFDNLTVLENLMVGYHSNMRSGLLLEGLSLPGSLSDESKARERAESIAEFLNIKDTLKMPAT SQPLGIQKKIEMGRALISQPKLLLLDEPAGGMNERETQNLAGLITQVQEEFGISVILVEHDMSLVMEICHKITVMNFGRK IACGNPADIQKNPKVQEAYLGKGEDASA
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0411
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI45446740, Length=235, Percent_Identity=30.2127659574468, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI47078218, Length=235, Percent_Identity=30.2127659574468, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI27881501, Length=239, Percent_Identity=30.1255230125523, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI30795238, Length=239, Percent_Identity=30.1255230125523, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI31657092, Length=256, Percent_Identity=26.5625, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI116734710, Length=241, Percent_Identity=26.5560165975104, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI21536376, Length=243, Percent_Identity=26.7489711934156, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI9961252, Length=214, Percent_Identity=27.5700934579439, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4505771, Length=200, Percent_Identity=27.5, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI6005701, Length=220, Percent_Identity=26.3636363636364, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI105990541, Length=230, Percent_Identity=28.2608695652174, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI27477115, Length=226, Percent_Identity=25.6637168141593, Blast_Score=65, Evalue=8e-11, Organism=Homo sapiens, GI42741659, Length=201, Percent_Identity=27.8606965174129, Blast_Score=65, Evalue=9e-11, Organism=Escherichia coli, GI1789864, Length=256, Percent_Identity=42.1875, Blast_Score=214, Evalue=6e-57, Organism=Escherichia coli, GI1789593, Length=253, Percent_Identity=31.2252964426877, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI87081791, Length=245, Percent_Identity=28.1632653061224, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI87081709, Length=243, Percent_Identity=28.8065843621399, Blast_Score=109, Evalue=2e-25, Organism=Escherichia coli, GI1790525, Length=245, Percent_Identity=27.3469387755102, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI1788472, Length=232, Percent_Identity=26.2931034482759, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI87082268, Length=251, Percent_Identity=27.4900398406374, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI48995001, Length=259, Percent_Identity=28.1853281853282, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1790467, Length=244, Percent_Identity=26.2295081967213, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI1787370, Length=247, Percent_Identity=27.1255060728745, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1787029, Length=249, Percent_Identity=26.5060240963855, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1787712, Length=243, Percent_Identity=25.9259259259259, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1786398, Length=249, Percent_Identity=26.5060240963855, Blast_Score=97, Evalue=7e-22, Organism=Escherichia coli, GI1788761, Length=244, Percent_Identity=26.6393442622951, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI87082267, Length=245, Percent_Identity=26.530612244898, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI48994883, Length=262, Percent_Identity=27.8625954198473, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI87081782, Length=257, Percent_Identity=27.6264591439689, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1790190, Length=246, Percent_Identity=25.2032520325203, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1788210, Length=229, Percent_Identity=26.6375545851528, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI48994943, Length=256, Percent_Identity=25, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1788225, Length=255, Percent_Identity=26.2745098039216, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1788450, Length=258, Percent_Identity=24.4186046511628, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI1789991, Length=243, Percent_Identity=27.5720164609054, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1790739, Length=238, Percent_Identity=30.2521008403361, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI1790162, Length=264, Percent_Identity=26.1363636363636, Blast_Score=84, Evalue=8e-18, Organism=Escherichia coli, GI1787792, Length=249, Percent_Identity=23.2931726907631, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1789032, Length=244, Percent_Identity=23.7704918032787, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI48994997, Length=242, Percent_Identity=26.8595041322314, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1787759, Length=260, Percent_Identity=24.6153846153846, Blast_Score=81, Evalue=9e-17, Organism=Escherichia coli, GI1786345, Length=254, Percent_Identity=24.8031496062992, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI145693107, Length=270, Percent_Identity=27.037037037037, Blast_Score=79, Evalue=5e-16, Organism=Escherichia coli, GI1789672, Length=259, Percent_Identity=23.9382239382239, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1788897, Length=224, Percent_Identity=24.5535714285714, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1789586, Length=244, Percent_Identity=25.8196721311475, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1786872, Length=257, Percent_Identity=24.124513618677, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1787500, Length=237, Percent_Identity=24.8945147679325, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1789873, Length=233, Percent_Identity=24.4635193133047, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1787089, Length=228, Percent_Identity=23.6842105263158, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1789963, Length=264, Percent_Identity=25, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1786253, Length=232, Percent_Identity=23.7068965517241, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787758, Length=238, Percent_Identity=23.9495798319328, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1788506, Length=235, Percent_Identity=25.9574468085106, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787547, Length=256, Percent_Identity=25, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786319, Length=236, Percent_Identity=24.5762711864407, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1788644, Length=256, Percent_Identity=25.390625, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786563, Length=259, Percent_Identity=23.5521235521236, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1787164, Length=252, Percent_Identity=21.8253968253968, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1789962, Length=251, Percent_Identity=24.3027888446215, Blast_Score=69, Evalue=5e-13, Organism=Escherichia coli, GI1786803, Length=254, Percent_Identity=23.2283464566929, Blast_Score=68, Evalue=6e-13, Organism=Escherichia coli, GI1789891, Length=241, Percent_Identity=25.7261410788382, Blast_Score=65, Evalue=3e-12, Organism=Escherichia coli, GI87081834, Length=242, Percent_Identity=25.2066115702479, Blast_Score=65, Evalue=3e-12, Organism=Escherichia coli, GI1786703, Length=234, Percent_Identity=23.9316239316239, Blast_Score=63, Evalue=3e-11, Organism=Caenorhabditis elegans, GI115533608, Length=236, Percent_Identity=29.6610169491525, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17565938, Length=232, Percent_Identity=28.448275862069, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17543740, Length=222, Percent_Identity=27.9279279279279, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI212646699, Length=186, Percent_Identity=26.8817204301075, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI25146777, Length=220, Percent_Identity=29.0909090909091, Blast_Score=64, Evalue=6e-11, Organism=Drosophila melanogaster, GI24643674, Length=224, Percent_Identity=26.7857142857143, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI116007184, Length=238, Percent_Identity=26.0504201680672, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI221500365, Length=238, Percent_Identity=26.0504201680672, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24666092, Length=213, Percent_Identity=26.7605633802817, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI85726357, Length=219, Percent_Identity=27.3972602739726, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 29237; Mature: 29237
Theoretical pI: Translated: 5.17; Mature: 5.17
Prosite motif: PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 4.1 %Met (Translated Protein) 5.6 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 4.1 %Met (Mature Protein) 5.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKDQGVDITMALLSIENLTKSFGGLVAVNELSMDVNQQEIHGLIGPNGAGKTTVFNCISK CCCCCCCHHHHHHHHHHHHHHHCCEEEEEHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHH FYTPDKGKILLDNGQNVLNLSPHQVIRCGISRTFQNVELFDNLTVLENLMVGYHSNMRSG HCCCCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC LLLEGLSLPGSLSDESKARERAESIAEFLNIKDTLKMPATSQPLGIQKKIEMGRALISQP EEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCC KLLLLDEPAGGMNERETQNLAGLITQVQEEFGISVILVEHDMSLVMEICHKITVMNFGRK CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCE IACGNPADIQKNPKVQEAYLGKGEDASA EECCCCCCCCCCCCHHHHHCCCCCCCCC >Mature Secondary Structure MKDQGVDITMALLSIENLTKSFGGLVAVNELSMDVNQQEIHGLIGPNGAGKTTVFNCISK CCCCCCCHHHHHHHHHHHHHHHCCEEEEEHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHH FYTPDKGKILLDNGQNVLNLSPHQVIRCGISRTFQNVELFDNLTVLENLMVGYHSNMRSG HCCCCCCEEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC LLLEGLSLPGSLSDESKARERAESIAEFLNIKDTLKMPATSQPLGIQKKIEMGRALISQP EEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCC KLLLLDEPAGGMNERETQNLAGLITQVQEEFGISVILVEHDMSLVMEICHKITVMNFGRK CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCE IACGNPADIQKNPKVQEAYLGKGEDASA EECCCCCCCCCCCCHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]
Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]