BacMap

Definition	Natranaerobius thermophilus JW/NM-WN-LF, complete genome.
Accession	NC_010718
Length	3,165,557

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The map label for this gene is ucpA [C]

Identifier: 188587038

GI number: 188587038

Start: 2605943

End: 2606800

Strand: Direct

Name: ucpA [C]

Synonym: Nther_2430

Alternate gene names: 188587038

Gene position: 2605943-2606800 (Clockwise)

Preceding gene: 188587037

Following gene: 188587040

Centisome position: 82.32

GC content: 39.63

Gene sequence:

>858_bases
ATGAAAGAATTCAAAAATAAGGTGGCGGTTATCACGGGGGCGGCCAATGGAATTGGTAAAGAACTGGCCTATGAAAGTGC
CCGAAGAGAAATGAAGGTGGTACTGGTTGACATAGATGAAACTAATCTTAAAAAGGTTGAACAGGAGCTATCAGATATGG
GCACCCAGGTCCTGTCTATAACAGCTGATGTCACGTTATATGAAAATGTAGAACGAGTAAAAGACGAAACTTTAAATAAG
TTCGGACAGGTTGATTTGCTATTCAATAATGCAGGTGTGGTAGTTTCTGGTCCTGTTTGGGAAATGCCAACTAAGGAATG
GGATTACATTACCGCTTCAAATATTCATAGCGTCATATATGGAATGAAAGCTTTTATACCTGTAATGATGGAACAGGGAA
CGGATTGTCATATAGTGAATACAGCTTCAGTGGCGGGACTGCTTTCCACCCCGGGAATGCCAGCTTATCATATGTCTAAA
TTTGCTAATGTAGGACTAACAGAAGCAACAAATCACCAGTTACGGGCAATGAATTCCAATATAAAAATGTCTGTTTATTG
CCCGGGCTTTATTCAAACAGATCTACACAATTGTGATGATAGAAGGCCACAACGATTTGCTATAGATCCCGATGAACCAT
ATTATCAAAGCACTAGCTACATGCTGGGCCGAGAAAAGGCCAGGTATGTAATTGAAACAGGTATACCATCAGATTCTGTG
GGATTAGCTGTATTTACAGCTATTGAAGAAGAACGGTTCTATATCCTTACCCATCCTCAATATAACAGCGTAATTGGCAA
AAGGATTAAAGACATGCTAGAAGGAATAGAACCTGATCCATCTATGTTTATTAGATAA

Upstream 100 bases:

>100_bases
TATAAACTGTTGGTATCACCGGTATCAATACAAGTTTGAAAATTTGTGAATTTGAAACTGATTTTTTTGACTTTGACTAA
CTGATTAGGGAGGGTTAGAA

Downstream 100 bases:

>100_bases
CATTTGATGTAATAGTATAACAAAGTTATTAAATAGACAGAACAGAGACAGTGGTAGGGGGACTTAAGCAGTACCCCCTA
CCTGTTTTTTGATCAAAAAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKEFKNKVAVITGAANGIGKELAYESARREMKVVLVDIDETNLKKVEQELSDMGTQVLSITADVTLYENVERVKDETLNK
FGQVDLLFNNAGVVVSGPVWEMPTKEWDYITASNIHSVIYGMKAFIPVMMEQGTDCHIVNTASVAGLLSTPGMPAYHMSK
FANVGLTEATNHQLRAMNSNIKMSVYCPGFIQTDLHNCDDRRPQRFAIDPDEPYYQSTSYMLGREKARYVIETGIPSDSV
GLAVFTAIEEERFYILTHPQYNSVIGKRIKDMLEGIEPDPSMFIR

Sequences:

>Translated_285_residues
MKEFKNKVAVITGAANGIGKELAYESARREMKVVLVDIDETNLKKVEQELSDMGTQVLSITADVTLYENVERVKDETLNK
FGQVDLLFNNAGVVVSGPVWEMPTKEWDYITASNIHSVIYGMKAFIPVMMEQGTDCHIVNTASVAGLLSTPGMPAYHMSK
FANVGLTEATNHQLRAMNSNIKMSVYCPGFIQTDLHNCDDRRPQRFAIDPDEPYYQSTSYMLGREKARYVIETGIPSDSV
GLAVFTAIEEERFYILTHPQYNSVIGKRIKDMLEGIEPDPSMFIR
>Mature_285_residues
MKEFKNKVAVITGAANGIGKELAYESARREMKVVLVDIDETNLKKVEQELSDMGTQVLSITADVTLYENVERVKDETLNK
FGQVDLLFNNAGVVVSGPVWEMPTKEWDYITASNIHSVIYGMKAFIPVMMEQGTDCHIVNTASVAGLLSTPGMPAYHMSK
FANVGLTEATNHQLRAMNSNIKMSVYCPGFIQTDLHNCDDRRPQRFAIDPDEPYYQSTSYMLGREKARYVIETGIPSDSV
GLAVFTAIEEERFYILTHPQYNSVIGKRIKDMLEGIEPDPSMFIR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI142976729, Length=281, Percent_Identity=28.8256227758007, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI25282469, Length=241, Percent_Identity=31.5352697095436, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI210032110, Length=195, Percent_Identity=31.2820512820513, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI40807363, Length=217, Percent_Identity=31.3364055299539, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI310128830, Length=212, Percent_Identity=28.7735849056604, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI310115468, Length=212, Percent_Identity=28.7735849056604, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI31542939, Length=194, Percent_Identity=32.9896907216495, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI4503817, Length=190, Percent_Identity=32.6315789473684, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI210032112, Length=195, Percent_Identity=30.2564102564103, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=32, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI66933014, Length=196, Percent_Identity=32.1428571428571, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40254992, Length=190, Percent_Identity=26.8421052631579, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI32483357, Length=193, Percent_Identity=27.979274611399, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=27.979274611399, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI5031737, Length=193, Percent_Identity=27.979274611399, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI109715829, Length=213, Percent_Identity=23.4741784037559, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=32.7485380116959, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI7706318, Length=297, Percent_Identity=23.5690235690236, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=30.1158301158301, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787335, Length=210, Percent_Identity=30.4761904761905, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=29.6747967479675, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788459, Length=258, Percent_Identity=25.1937984496124, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786701, Length=191, Percent_Identity=30.8900523560209, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787905, Length=128, Percent_Identity=32.8125, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082160, Length=202, Percent_Identity=23.7623762376238, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=196, Percent_Identity=30.6122448979592, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=30.7291666666667, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17564282, Length=209, Percent_Identity=27.7511961722488, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17508895, Length=213, Percent_Identity=28.169014084507, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=226, Percent_Identity=30.0884955752212, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=28.9473684210526, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=28.4584980237154, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=26.3779527559055, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=201, Percent_Identity=31.3432835820896, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=26.5151515151515, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=27.037037037037, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=203, Percent_Identity=26.1083743842365, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=179, Percent_Identity=31.2849162011173, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=190, Percent_Identity=25.7894736842105, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=201, Percent_Identity=29.3532338308458, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=26.2357414448669, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=202, Percent_Identity=28.7128712871287, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=202, Percent_Identity=31.1881188118812, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71997402, Length=191, Percent_Identity=28.7958115183246, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=203, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=192, Percent_Identity=23.4375, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=235, Percent_Identity=26.3829787234043, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=171, Percent_Identity=30.9941520467836, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=204, Percent_Identity=28.4313725490196, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=25.1908396946565, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17570069, Length=189, Percent_Identity=27.5132275132275, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=187, Percent_Identity=31.0160427807487, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=27.9187817258883, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320089, Length=267, Percent_Identity=25.8426966292135, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI23397609, Length=194, Percent_Identity=31.9587628865979, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571526, Length=197, Percent_Identity=31.4720812182741, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24644339, Length=227, Percent_Identity=29.5154185022026, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281364892, Length=175, Percent_Identity=32.5714285714286, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24581726, Length=201, Percent_Identity=32.3383084577114, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357041, Length=231, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640492, Length=213, Percent_Identity=27.6995305164319, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28571387, Length=202, Percent_Identity=29.7029702970297, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355319, Length=194, Percent_Identity=30.9278350515464, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640442, Length=230, Percent_Identity=32.1739130434783, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI221510726, Length=193, Percent_Identity=32.1243523316062, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21355631, Length=175, Percent_Identity=29.1428571428571, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24639444, Length=195, Percent_Identity=27.1794871794872, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24641232, Length=203, Percent_Identity=26.6009852216749, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI116007236, Length=207, Percent_Identity=26.5700483091787, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21358495, Length=204, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24663911, Length=201, Percent_Identity=27.363184079602, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584748, Length=220, Percent_Identity=28.6363636363636, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161076933, Length=220, Percent_Identity=28.6363636363636, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584752, Length=203, Percent_Identity=30.0492610837438, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17737361, Length=203, Percent_Identity=29.064039408867, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281364494, Length=203, Percent_Identity=25.1231527093596, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24648944, Length=196, Percent_Identity=26.0204081632653, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007238, Length=193, Percent_Identity=26.4248704663212, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=24.1025641025641, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31980; Mature: 31980

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEFKNKVAVITGAANGIGKELAYESARREMKVVLVDIDETNLKKVEQELSDMGTQVLSI
CCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCEEEEE
TADVTLYENVERVKDETLNKFGQVDLLFNNAGVVVSGPVWEMPTKEWDYITASNIHSVIY
EECCHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCCCCCCCCCCCEEEHHHHHHHHH
GMKAFIPVMMEQGTDCHIVNTASVAGLLSTPGMPAYHMSKFANVGLTEATNHQLRAMNSN
HHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHEEECCC
IKMSVYCPGFIQTDLHNCDDRRPQRFAIDPDEPYYQSTSYMLGREKARYVIETGIPSDSV
CEEEEEECCHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHHCCCCCCEEEECCCCCCCC
GLAVFTAIEEERFYILTHPQYNSVIGKRIKDMLEGIEPDPSMFIR
CEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MKEFKNKVAVITGAANGIGKELAYESARREMKVVLVDIDETNLKKVEQELSDMGTQVLSI
CCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHCCEEEEE
TADVTLYENVERVKDETLNKFGQVDLLFNNAGVVVSGPVWEMPTKEWDYITASNIHSVIY
EECCHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEECCCCCCCCCCCCEEEHHHHHHHHH
GMKAFIPVMMEQGTDCHIVNTASVAGLLSTPGMPAYHMSKFANVGLTEATNHQLRAMNSN
HHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHEEECCC
IKMSVYCPGFIQTDLHNCDDRRPQRFAIDPDEPYYQSTSYMLGREKARYVIETGIPSDSV
CEEEEEECCHHHHHHCCCCCCCCCEEECCCCCCCCCCHHHHHCCCCCCEEEECCCCCCCC
GLAVFTAIEEERFYILTHPQYNSVIGKRIKDMLEGIEPDPSMFIR
CEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA