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The map label for this gene is fabZ

Identifier: 188586940

GI number: 188586940

Start: 2478568

End: 2478996

Strand: Reverse

Name: fabZ

Synonym: Nther_2332

Alternate gene names: 188586940

Gene position: 2478996-2478568 (Counterclockwise)

Preceding gene: 188586941

Following gene: 188586938

Centisome position: 78.31

GC content: 42.66

Gene sequence:

>429_bases
TTGAAGGATATTAATGAAATCAAAGAACTGATTCCCCATCGCTATCCCATCTTAATGGTAGATAGATTGGAAGAATTGGA
ACCAGGACATAGGGCTAAAGGTGTTAAAAACGTATCTGCTAACGAACCTTTTTTACAGGGACATTTCCCAGATCGTCCTT
TGATGCCTGGAGTTTTACAAATAGAAGCCATGGCCCAGGTAGGGGCCTGTGCTCTGATGAGCCTTCCAGAAAACGAAGGA
AAACTTGCCGTTTTCGGTGGTGTGGATAAAGTTAAATTTAAAAGACAAGTACAACCAGGGGATGTGCTCAGTATAGAGGT
TGAGCTAACCCGGGTTAAAGGTAGTATCGGAAAAGGTGAAGGAAAGGTATATGTAGGAGATGAACTAGCGGCCCAAGGTC
AGCTCACTTTTGCTCTTGTGGAAAAATAA

Upstream 100 bases:

>100_bases
TATGAGATAGAAGAATACATCTAACACTCTCGAACAGTCGTATTAGAGCTTTATAATCAACTATTCATCATTATTAAATC
TGAACGAAGGAGGTTTTATT

Downstream 100 bases:

>100_bases
GACGGGCTCGGCGAATAGCATCGTCACCAAATTTTTCTCGCATTTCATCAAGGGTCCATTGTAGCTGCTGTTCTTTTTCG
TACTGTTCATTAGACATATC

Product: 3-hydroxyacyl-(acyl-carrier-protein) dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MKDINEIKELIPHRYPILMVDRLEELEPGHRAKGVKNVSANEPFLQGHFPDRPLMPGVLQIEAMAQVGACALMSLPENEG
KLAVFGGVDKVKFKRQVQPGDVLSIEVELTRVKGSIGKGEGKVYVGDELAAQGQLTFALVEK

Sequences:

>Translated_142_residues
MKDINEIKELIPHRYPILMVDRLEELEPGHRAKGVKNVSANEPFLQGHFPDRPLMPGVLQIEAMAQVGACALMSLPENEG
KLAVFGGVDKVKFKRQVQPGDVLSIEVELTRVKGSIGKGEGKVYVGDELAAQGQLTFALVEK
>Mature_142_residues
MKDINEIKELIPHRYPILMVDRLEELEPGHRAKGVKNVSANEPFLQGHFPDRPLMPGVLQIEAMAQVGACALMSLPENEG
KLAVFGGVDKVKFKRQVQPGDVLSIEVELTRVKGSIGKGEGKVYVGDELAAQGQLTFALVEK

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=137, Percent_Identity=43.7956204379562, Blast_Score=117, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_NATTJ (B2A8L3)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001918485.1
- ProteinModelPortal:   B2A8L3
- SMR:   B2A8L3
- GeneID:   6315925
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_2332
- HOGENOM:   HBG433282
- OMA:   NVSANES
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 15545; Mature: 15545

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDINEIKELIPHRYPILMVDRLEELEPGHRAKGVKNVSANEPFLQGHFPDRPLMPGVLQ
CCCHHHHHHHCCCCCCEEEECCHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHH
IEAMAQVGACALMSLPENEGKLAVFGGVDKVKFKRQVQPGDVLSIEVELTRVKGSIGKGE
HHHHHHHCCEEEEECCCCCCCEEEECCCCCEEHEECCCCCCEEEEEEEEEEECCCCCCCC
GKVYVGDELAAQGQLTFALVEK
CEEEECCCCCCCCCEEEEEECC
>Mature Secondary Structure
MKDINEIKELIPHRYPILMVDRLEELEPGHRAKGVKNVSANEPFLQGHFPDRPLMPGVLQ
CCCHHHHHHHCCCCCCEEEECCHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHH
IEAMAQVGACALMSLPENEGKLAVFGGVDKVKFKRQVQPGDVLSIEVELTRVKGSIGKGE
HHHHHHHCCEEEEECCCCCCCEEEECCCCCEEHEECCCCCCEEEEEEEEEEECCCCCCCC
GKVYVGDELAAQGQLTFALVEK
CEEEECCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA