Click here to switch to the map view.

The map label for this gene is comFA [H]

Identifier: 188586868

GI number: 188586868

Start: 2401400

End: 2403550

Strand: Reverse

Name: comFA [H]

Synonym: Nther_2259

Alternate gene names: 188586868

Gene position: 2403550-2401400 (Counterclockwise)

Preceding gene: 188586869

Following gene: 188586866

Centisome position: 75.93

GC content: 41.98

Gene sequence:

>2151_bases
ATGTTTAAATTAGTTATGATTCACTTGGATCATAAATCGGTCGGTTTAATTGACAATGGGAGAGGTGGCACAACTAAAGT
GAAGCCAAAGATGAAGGCCCCAAGGATATTTCGCTTTGATTGCCAAATTAGGCCTCTGTGTTTATCTTATACCGAGATTC
CATCTCAGGGATATGATATTAACCAGGCTTGGCGACTTTGTGATTCGGGACAGGCCTTTTGGGAGCTGTTACCCTTCGCC
CCAAGTACAAAACTACAAGGACATAATCAGGTGAGAACCGACTACAACAGCGCCTTACAGGGAAGGGCGCTGTTTTTTAA
TGAAATATTGTCTGAAATACAACCCGATCTCGCTTTATTGAAAGGCCGAAACCAGGATTTAGGCCCAAAGGTATTAGAAC
GGGAAATAGAAGAAATATTTAAAAGCTTAATCTATTTAAATCCAATAATTGTTCCAGGAGTCATATCAGCCCATCATCCA
GCTTATCAGAAATTGCTTGATATAGTTTTTCAAACAGATAAGCCTTCTATGGCGAAAAAGAGAAAGGGTGAAAGTTCTGA
TCTAAAACATATCATTCTAAAACATACTTTTTTCACAAAAATTAAATCCTTCAGCAAAAACCTCAGTAACAAAATCTTCC
TCGACAATTCAACTAAGGGCATATGCCTACGCTGTGGCTCCGATAAGCTATCAAATATCGAGGGAATCGAGGAATTAGAA
GATCCCTGTCCCAGATGTGGTAGATACTGTCACTCCTGTCGAGAATGTTATCAGATGGGCGAGTCCACAGAATGCACACC
CCTGTTTCTTTTCCCAGAAAGCTGTCTTGTCAACAACAATGGAGAAGATTCACATGTTTTAAACCTGGATTTTAAGCTGA
CACCGGCACAAAAGCGAGCCTATGAAAAGGCCCAGAAATTTGTGGGATTCAATTCTTATCGCTTTGATACTTCCTATTCC
TATTCCTGTTCCTCCTCTTCCTCTTCCTCCTCCTCTTCTTCTTCTTCTTCGCCCCTTACTGCCCTAATCTACGCCGTCTG
CGGTGCTGGTAAGACAGAAACCGTCTTTGGGGCAGTACTATCTGTATTAAACCGGGGAGGCAAGGTATTGTATGCCACTC
CCCGGAGGGACTTGGTACGGGAATTATCGGAGCGGCTGCAAAATGCTTTCCCCCGGACCAAGATTTTAGCTATTTATGGT
GGCAGCAAAAACAAATTTTCTGATGGTGAACTAATAATTGCCACTACTCATCAGGTTATGAGGTTTTATGATGCCTTTGA
GTTGGTGATTTTAGATGAGGTAGATGCTTTTCCTTATCACGGGAGTGATCGATTACCCTTATTAATTCGTAGGGCTCGCA
AAAAAAGCCAATATCCTAAAAGGGAGAGTTGGAATTATTCTGGGCCAGAAGCAAAAATTATCTACATAACGGCAACACCT
CATAAAGATCTAATCCAGGGAAAGGGACGTGAACTTTCTAATCATACCAATCACACAAATTTTTCTAATCCTTTTAATCC
TATCATGAAAGAAAATCCACCGGAATTGATTACAATCCCGGCCAGGTATCATGGCTATCCAGCACCGGAACCAAAATTGT
TAAAAGGCACCAAAAAAACCCTGTTTCTAAATGATCAACTAGAGAAATTATTATTAAAAAACACTGGTGTAAAGCCAATC
TTTGTGTTTGTCCCTTCTGTTTATATGGTGGAAAAAGTTTGCCGGGCTCTGTCCCACTGGCTTAAATTAAAAGCCCATCA
GCAGCCTCACTGGGAACAAATTTCCGAACAAAGGACCAAGAAAATTTCACAGGCCGTGGTTTCCGGGGTGTCCTCTCAAG
ACCCTGACAGGGACCAAAAGCGCCTGGATTTTCATAATGGCGAAATAGATATTTTGGTGACAACTACGATCATGGAGCGG
GGGATTACAGTTACAGGAGTTCAAGTGGTGGTTCTGTTTGCAGATCATGAAATATTCGATAGTCGAACCTTGATTCAAAT
GGCGGGACGAGCCGGCAGAAAAAAACAGGACCCTACTGGAGAGGTCCTGTTTATAGGCGAGAAAATCACTAAAGATATGA
AAACTGCCAGGGCCGCCATTGTCAAGTTAAACCGCGAAGGACGCAGACTGGGTTTTTTAATTGATCCCTAA

Upstream 100 bases:

>100_bases
AAACTACAAGGTGACATGAATTTAAATTAAGTAAAATAATAAAAAGAGGATATTTCCATTTTAGGGAGAATATTAAATTT
AGATTAATTTTAAAAAGTTT

Downstream 100 bases:

>100_bases
TCAAAGACTGATGATACCATTGTGCTGTTGTAATGCTATTCGTAATCAAATACATTTTGGAATTCTTCCGGGAATTCATT
TAAAAAGTAAACTGATAAAG

Product: helicase domain protein

Products: NA

Alternate protein names: ATP-dependent helicase ComFA [H]

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MFKLVMIHLDHKSVGLIDNGRGGTTKVKPKMKAPRIFRFDCQIRPLCLSYTEIPSQGYDINQAWRLCDSGQAFWELLPFA
PSTKLQGHNQVRTDYNSALQGRALFFNEILSEIQPDLALLKGRNQDLGPKVLEREIEEIFKSLIYLNPIIVPGVISAHHP
AYQKLLDIVFQTDKPSMAKKRKGESSDLKHIILKHTFFTKIKSFSKNLSNKIFLDNSTKGICLRCGSDKLSNIEGIEELE
DPCPRCGRYCHSCRECYQMGESTECTPLFLFPESCLVNNNGEDSHVLNLDFKLTPAQKRAYEKAQKFVGFNSYRFDTSYS
YSCSSSSSSSSSSSSSSPLTALIYAVCGAGKTETVFGAVLSVLNRGGKVLYATPRRDLVRELSERLQNAFPRTKILAIYG
GSKNKFSDGELIIATTHQVMRFYDAFELVILDEVDAFPYHGSDRLPLLIRRARKKSQYPKRESWNYSGPEAKIIYITATP
HKDLIQGKGRELSNHTNHTNFSNPFNPIMKENPPELITIPARYHGYPAPEPKLLKGTKKTLFLNDQLEKLLLKNTGVKPI
FVFVPSVYMVEKVCRALSHWLKLKAHQQPHWEQISEQRTKKISQAVVSGVSSQDPDRDQKRLDFHNGEIDILVTTTIMER
GITVTGVQVVVLFADHEIFDSRTLIQMAGRAGRKKQDPTGEVLFIGEKITKDMKTARAAIVKLNREGRRLGFLIDP

Sequences:

>Translated_716_residues
MFKLVMIHLDHKSVGLIDNGRGGTTKVKPKMKAPRIFRFDCQIRPLCLSYTEIPSQGYDINQAWRLCDSGQAFWELLPFA
PSTKLQGHNQVRTDYNSALQGRALFFNEILSEIQPDLALLKGRNQDLGPKVLEREIEEIFKSLIYLNPIIVPGVISAHHP
AYQKLLDIVFQTDKPSMAKKRKGESSDLKHIILKHTFFTKIKSFSKNLSNKIFLDNSTKGICLRCGSDKLSNIEGIEELE
DPCPRCGRYCHSCRECYQMGESTECTPLFLFPESCLVNNNGEDSHVLNLDFKLTPAQKRAYEKAQKFVGFNSYRFDTSYS
YSCSSSSSSSSSSSSSSPLTALIYAVCGAGKTETVFGAVLSVLNRGGKVLYATPRRDLVRELSERLQNAFPRTKILAIYG
GSKNKFSDGELIIATTHQVMRFYDAFELVILDEVDAFPYHGSDRLPLLIRRARKKSQYPKRESWNYSGPEAKIIYITATP
HKDLIQGKGRELSNHTNHTNFSNPFNPIMKENPPELITIPARYHGYPAPEPKLLKGTKKTLFLNDQLEKLLLKNTGVKPI
FVFVPSVYMVEKVCRALSHWLKLKAHQQPHWEQISEQRTKKISQAVVSGVSSQDPDRDQKRLDFHNGEIDILVTTTIMER
GITVTGVQVVVLFADHEIFDSRTLIQMAGRAGRKKQDPTGEVLFIGEKITKDMKTARAAIVKLNREGRRLGFLIDP
>Mature_716_residues
MFKLVMIHLDHKSVGLIDNGRGGTTKVKPKMKAPRIFRFDCQIRPLCLSYTEIPSQGYDINQAWRLCDSGQAFWELLPFA
PSTKLQGHNQVRTDYNSALQGRALFFNEILSEIQPDLALLKGRNQDLGPKVLEREIEEIFKSLIYLNPIIVPGVISAHHP
AYQKLLDIVFQTDKPSMAKKRKGESSDLKHIILKHTFFTKIKSFSKNLSNKIFLDNSTKGICLRCGSDKLSNIEGIEELE
DPCPRCGRYCHSCRECYQMGESTECTPLFLFPESCLVNNNGEDSHVLNLDFKLTPAQKRAYEKAQKFVGFNSYRFDTSYS
YSCSSSSSSSSSSSSSSPLTALIYAVCGAGKTETVFGAVLSVLNRGGKVLYATPRRDLVRELSERLQNAFPRTKILAIYG
GSKNKFSDGELIIATTHQVMRFYDAFELVILDEVDAFPYHGSDRLPLLIRRARKKSQYPKRESWNYSGPEAKIIYITATP
HKDLIQGKGRELSNHTNHTNFSNPFNPIMKENPPELITIPARYHGYPAPEPKLLKGTKKTLFLNDQLEKLLLKNTGVKPI
FVFVPSVYMVEKVCRALSHWLKLKAHQQPHWEQISEQRTKKISQAVVSGVSSQDPDRDQKRLDFHNGEIDILVTTTIMER
GITVTGVQVVVLFADHEIFDSRTLIQMAGRAGRKKQDPTGEVLFIGEKITKDMKTARAAIVKLNREGRRLGFLIDP

Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]

COG id: COG4098

COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 80946; Mature: 80946

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKLVMIHLDHKSVGLIDNGRGGTTKVKPKMKAPRIFRFDCQIRPLCLSYTEIPSQGYDI
CEEEEEEEECCCCCCEEECCCCCCEECCCCCCCCEEEEEECCCCEEEEEHHHCCCCCCCH
NQAWRLCDSGQAFWELLPFAPSTKLQGHNQVRTDYNSALQGRALFFNEILSEIQPDLALL
HHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHH
KGRNQDLGPKVLEREIEEIFKSLIYLNPIIVPGVISAHHPAYQKLLDIVFQTDKPSMAKK
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCHHCCCHHHHHHHHHHHCCCCCHHHHH
RKGESSDLKHIILKHTFFTKIKSFSKNLSNKIFLDNSTKGICLRCGSDKLSNIEGIEELE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCHHCCCCCHHHHH
DPCPRCGRYCHSCRECYQMGESTECTPLFLFPESCLVNNNGEDSHVLNLDFKLTPAQKRA
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHEECCCCCCCEEEEEEEEECCHHHHH
YEKAQKFVGFNSYRFDTSYSYSCSSSSSSSSSSSSSSPLTALIYAVCGAGKTETVFGAVL
HHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
SVLNRGGKVLYATPRRDLVRELSERLQNAFPRTKILAIYGGSKNKFSDGELIIATTHQVM
HHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEEHHHHH
RFYDAFELVILDEVDAFPYHGSDRLPLLIRRARKKSQYPKRESWNYSGPEAKIIYITATP
HHHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECC
HKDLIQGKGRELSNHTNHTNFSNPFNPIMKENPPELITIPARYHGYPAPEPKLLKGTKKT
CHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCEEEECHHHCCCCCCCCHHHCCCCCE
LFLNDQLEKLLLKNTGVKPIFVFVPSVYMVEKVCRALSHWLKLKAHQQPHWEQISEQRTK
EEECHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KISQAVVSGVSSQDPDRDQKRLDFHNGEIDILVTTTIMERGITVTGVQVVVLFADHEIFD
HHHHHHHHCCCCCCCCCHHHHHCCCCCEEEEEEEEEHHHCCCEEEEEEEEEEEECCHHHC
SRTLIQMAGRAGRKKQDPTGEVLFIGEKITKDMKTARAAIVKLNREGRRLGFLIDP
CHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHEECCCCCEEEEEECC
>Mature Secondary Structure
MFKLVMIHLDHKSVGLIDNGRGGTTKVKPKMKAPRIFRFDCQIRPLCLSYTEIPSQGYDI
CEEEEEEEECCCCCCEEECCCCCCEECCCCCCCCEEEEEECCCCEEEEEHHHCCCCCCCH
NQAWRLCDSGQAFWELLPFAPSTKLQGHNQVRTDYNSALQGRALFFNEILSEIQPDLALL
HHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHH
KGRNQDLGPKVLEREIEEIFKSLIYLNPIIVPGVISAHHPAYQKLLDIVFQTDKPSMAKK
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCHHCCCHHHHHHHHHHHCCCCCHHHHH
RKGESSDLKHIILKHTFFTKIKSFSKNLSNKIFLDNSTKGICLRCGSDKLSNIEGIEELE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCHHCCCCCHHHHH
DPCPRCGRYCHSCRECYQMGESTECTPLFLFPESCLVNNNGEDSHVLNLDFKLTPAQKRA
CCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHEECCCCCCCEEEEEEEEECCHHHHH
YEKAQKFVGFNSYRFDTSYSYSCSSSSSSSSSSSSSSPLTALIYAVCGAGKTETVFGAVL
HHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHH
SVLNRGGKVLYATPRRDLVRELSERLQNAFPRTKILAIYGGSKNKFSDGELIIATTHQVM
HHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEEHHHHH
RFYDAFELVILDEVDAFPYHGSDRLPLLIRRARKKSQYPKRESWNYSGPEAKIIYITATP
HHHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECC
HKDLIQGKGRELSNHTNHTNFSNPFNPIMKENPPELITIPARYHGYPAPEPKLLKGTKKT
CHHHHCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCEEEECHHHCCCCCCCCHHHCCCCCE
LFLNDQLEKLLLKNTGVKPIFVFVPSVYMVEKVCRALSHWLKLKAHQQPHWEQISEQRTK
EEECHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
KISQAVVSGVSSQDPDRDQKRLDFHNGEIDILVTTTIMERGITVTGVQVVVLFADHEIFD
HHHHHHHHCCCCCCCCCHHHHHCCCCCEEEEEEEEEHHHCCCEEEEEEEEEEEECCHHHC
SRTLIQMAGRAGRKKQDPTGEVLFIGEKITKDMKTARAAIVKLNREGRRLGFLIDP
CHHHHHHHCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412657; 9384377 [H]